Ultra Potent-C 1000

Ultra Potent-C 1000

Metagenics4.7 (109 ratings)
Format:Tablet Quantity: 90 Tablet(s) · 90 servings
Goals
$39.95 $0.44 per serving

Product analysis

47 out of 100

Ultra Potent-C 1000 supplies vitamin C for normal immune function and collagen formation, especially when intake is low. Most ingredient forms are unspecified, making the broader mix hard to compare.

AI assessment of the formula, label and price. How scoring works

Nutrient Quality20

Most ingredient forms are unclear, leaving absorption quality uncertain across the blend. Niacinamide ascorbate can be identified elsewhere on the label, but that does not settle the other forms.

Ingredient Transparency63

All ingredient amounts are stated, allowing serving comparisons. The main ingredient declarations omit forms, though niacinamide ascorbate is identifiable elsewhere on the label.

Value For Money40

The cost for vitamin C is moderate, while niacin is costly for what it supplies. Value remains uncertain for most of the additional ingredients.

Customer Satisfaction71

Customer ratings are generally positive. Feedback from 109 ratings gives a moderate picture of satisfaction.

Product Focus66

Vitamin C supplies the clearest support for normal immune and skin functions. The added ingredients do not establish routine cosmetic or inflammation benefits in adequately nourished adults.

Format
Tablet
Container
90 Tablet(s)
Per serving
$0.44
Customer rating
4.7 · 109 ratings
Report analysis

Goals

Immunity
Impact
High effect
C Ingredient FitC PathwaysA+ EvidenceA+ Formulation Logic
Vitamin C · 1000 mg
Study evidence
Lysine Supportive 2 studies
Vitamin C Supportive 53 studies
Everyday Health
Impact
High effect
C+ Ingredient FitB- PathwaysB- EvidenceA+ Formulation Logic
Vitamin C · 1000 mg
Study evidence
Vitamin C Supportive 56 studies
Impact
High effect
C Ingredient FitD+ PathwaysA- EvidenceA+ Formulation Logic
Vitamin C · 1000 mg
Study evidence
Vitamin C Supportive 50 studies
Skin Health
Impact
Moderate effect
C Ingredient FitF PathwaysA+ EvidenceA+ Formulation Logic
Vitamin C · 1000 mgGluthathione · 5 mg
Study evidence
Niacin Supportive 61 studies
Vitamin C Supportive 53 studies

Ingredients

IngredientAmount per servingScore
Vitamin C
1000 mg 65
Niacin
70 mg 65
Calcium
40 mg
Sodium
10 mg
L-Lysine
33 mg
Citrus Bioflavonoid Complex
32 mg
Tetrasodium Pyrophosphate
14 mg
Alpha D-Ribofuranose
13 mg
Xylitol
9 mg
L-Cysteine
8 mg
L-Glutathione
5 mg
Gluten Free Adults 18–50 Vegetarian
Report overview
Vitamin C · 1000 mg OverallScore65
C+ Active Ingredient Quality & BioavailabilityB- Dose, Safety & Label TransparencyD+ Value
Each serving provides 1000 mg of vitamin C at a moderate cost per gram. The product is described as non-acidic, but its vitamin C row does not name a source. Several forms appear under Other Ingredients, with proportions unknown, and sweeteners are present.
How this ingredient is rated

Active Ingredient Quality & Bioavailability67

The main vitamin C row does not name a source, though several forms appear in Other Ingredients. The product is described as non-acidic and gentle on the stomach.
Vitamin C Chemical Form & Delivery System
The vitamin C row does not name a source. Other Ingredients lists Niacinamide Ascorbate, Ascorbic Acid, Sodium Ascorbate, Magnesium Ascorbate, Ascorbyl Palmitate and Potassium Ascorbate; their proportions are unknown.
Gastric Comfort & pH Balance
The product is described as non-acidic and gentle on the stomach; that claim does not establish complete buffering.

Dose, Safety & Label Transparency71

Each serving provides 1000 mg of vitamin C. Sweeteners are present, and some mineral amounts are not stated.
Optimal Dosage Targeting
Each serving provides 1000 mg of vitamin C.
Purity & Excipient Quality
The other-ingredient panel includes sweeteners.
Mineral & Source Transparency
The vitamin C amount is stated, but the main row does not name its source and the matching mineral amounts are incomplete.

Value50

The cost per gram of vitamin C is moderate.
Price per Gram of Vitamin C
The cost per gram of vitamin C is moderate.
Niacin · 70 mg OverallScore65
A- Active Ingredient Quality & BioavailabilityC+ Dose, Safety & Label TransparencyF Value
70 mg of niacin per serving comes at a high serving cost. The niacin entry names no source; niacinamide ascorbate appears in Other Ingredients.
How this ingredient is rated

Active Ingredient Quality & Bioavailability86

The niacin entry names no source; niacinamide ascorbate appears in Other Ingredients.
Niacin Form & Goal Alignment
The niacin entry names no source; niacinamide ascorbate appears in Other Ingredients.
Precursor Source Quality
niacinamide ascorbate is listed in Other Ingredients.

Dose, Safety & Label Transparency67

The niacin entry names no source; niacinamide ascorbate appears in Other Ingredients.
Clarity of Chemical Form
The niacin entry names no source; niacinamide ascorbate appears in Other Ingredients.
Form-Specific Dosage Efficacy
70 mg per serving is the amount used; its suitability for the intended purpose remains uncertain.
Flush Risk & Safety Labeling
No no-flush claim is recorded.

Value20

The cost per serving is high.
Price Per Effective Serving
The cost per serving is high.
Report alternatives

Sources

Published studies used for the product analysis and the top-ranked studies for each ingredient and goal.

  1. Glutathione reduces the toxicity and improves quality of life of women diagnosed with ovarian cancer treated with cisplatin: results of a double-blind, randomised trial.
    Smyth JF; Bowman A; Perren T; Wilkinson P; Prescott RJ; Quinn KJ; Tedeschi M · Annals of oncology : official journal of the European Society for Medical Oncology · 1997
    Randomized trial151 participantsEveryday Health forGluthathione
  2. Glutathione and morbidity in a community-based sample of elderly.
    Julius M; Lang CA; Gleiberman L; Harburg E; DiFranceisco W; Schork A · Journal of clinical epidemiology · 1995
    Cross-sectional study33 participantsEveryday Health forGluthathione
  3. The role of zinc, copper, plasma glutathione peroxidase enzyme, and vitamins in the development of allergic diseases in early childhood: The Polish mother and child cohort study.
    Stelmach I; Grzelewski T; Bobrowska-Korzeniowska M; Kopka M; Majak P; Jerzynska J; Stelmach W; Polańska K; Sobala W; Gromadzińska J; Wąsowicz W; Hanke W · Allergy and asthma proceedings · 2014
    Cohort study240 participantsEveryday Health forGluthathione
  4. Status of glutathione and other thiols and disulfides in human plasma.
    Kleinman WA; Richie JP · Biochemical pharmacology · 2000
    Cross-sectional studyEveryday Health forGluthathione
  5. Impact of a tailored exercise regimen on physical capacity and plasma proteome profile in post-COVID-19 condition.
    Chowdhury MMH; Fontaine MN; Lord SE; Quenum AJI; Limoges MA; Rioux-Perreault C; Lucier JF; Cliche DO; Levesque D; Boisvert FM; Cantin AM; Allard-Chamard H; Menendez A; Ilangumaran S; Piché A; Dionne IJ; Ramanathan S · Frontiers in physiology · 2024
    Single-arm trialEveryday Health forGluthathione
  6. Dietary intake and blood concentrations of antioxidants and the risk of cardiovascular disease, total cancer, and all-cause mortality: a systematic review and dose-response meta-analysis of prospective studies.
    Aune D; Keum N; Giovannucci E; Fadnes LT; Boffetta P; Greenwood DC; Tonstad S; Vatten LJ; Riboli E; Norat T · The American journal of clinical nutrition · 2019
    Meta-analysis69 studies pooledEveryday Health forVitamin C
  7. Scientific Opinion on the substantiation of a health claim related to vitamin C and increasing non haem iron absorption pursuant to Article 14 of Regulation (EC) No 1924/2006.
    EFSA Panel on Dietetic Products, Nutrition and Allergies (NDA) · EFSA journal. European Food Safety Authority · 2026
    Guideline / consensusEveryday Health forVitamin C
  8. Vitamin C Depletion and All-Cause Mortality in Renal Transplant Recipients.
    Sotomayor CG; Eisenga MF; Gomes Neto AW; Ozyilmaz A; Gans ROB; Jong WHA; Zelle DM; Berger SP; Gaillard CAJM; Navis GJ; Bakker SJ · Nutrients · 2018
    Cohort study598 participantsEveryday Health forVitamin C
  9. Associations of Serum Biomarkers of Fruit and Vegetable Intake With the Risk of Cause-Specific Mortality and All-Cause Mortality: A National Prospective Cohort Study.
    Pu L; Zhang R; Wang X; Zhao T; Sun H; Han L · Frontiers in nutrition · 2022
    Cohort study12,530 participantsEveryday Health forVitamin C
  10. Relation between plasma ascorbic acid and mortality in men and women in EPIC-Norfolk prospective study: a prospective population study. European Prospective Investigation into Cancer and Nutrition.
    Khaw KT; Bingham S; Welch A; Luben R; Wareham N; Oakes S; Day N · Lancet (London, England) · 2001
    Cohort study19,496 participantsEveryday Health forVitamin C
  11. Lysine-fortified wheat flour improves the nutritional and immunological status of wheat-eating families in northern China.
    Zhao W; Zhai F; Zhang D; An Y; Liu Y; He Y; Ge K; Scrimshaw NS · Food and nutrition bulletin · 2004
    Clinical trial264 participantsImmunity forLysine
  12. Success of L-lysine therapy in frequently recurrent herpes simplex infection. Treatment and prophylaxis
    R S Griffith, D E Walsh, K H Myrmel, R W Thompson, A Behforooz · Dermatologica · 1987
    Non-randomized trial52 participantsImmunity forLysine
  13. Vitamin C and contribution to the normal function of the immune system: evaluation of a health claim pursuant to Article 14 of Regulation (EC) No 1924/2006.
    EFSA Panel on Dietetic Products, Nutrition and Allergies (NDA) · EFSA journal. European Food Safety Authority · 2026
    Guideline / consensusImmunity forVitamin C
  14. Therapeutic effects of high-dose vitamin C supplementation in patients with COVID-19: a meta-analysis.
    Sun L; Zhao JH; Fan WY; Feng B; Liu WW; Chen RQ; Ban C; Dang AG; Wang M; Luo KT; Zhou GY; Yu FF; Ba Y · Nutrition reviews · 2024
    Meta-analysis2,334 participants14 studies pooledImmunity forVitamin C
  15. Effect of micronutrient supplements on influenza and other respiratory tract infections among adults: a systematic review and meta-analysis.
    Abioye AI; Bromage S; Fawzi W · BMJ global health · 2021
    Meta-analysisImmunity forVitamin C
  16. New evidence for antioxidant properties of vitamin C.
    Vojdani A; Bazargan M; Vojdani E; Wright J · Cancer detection and prevention · 2001
    Randomized trial20 participantsImmunity forVitamin C
  17. Enhanced Vitamin C Delivery: A Systematic Literature Review Assessing the Efficacy and Safety of Alternative Supplement Forms in Healthy Adults.
    Calder PC; Kreider RB; McKay DL · Nutrients · 2025
    Systematic review13 studies pooledImmunity forVitamin C
  18. Serum type III procollagen, procollagen V, tumour necrosis factor-a, interleukin-6 in liver cirrhosis after antiviral treatment.
    Li W; Liu X; Bi F · Journal of medical biochemistry · 2025
    Randomized trial92 participantsInflammation forGlutathione
  19. Evaluation of the antioxidant and anti-inflammatory effect of sublingual glutathione on COPD patients.
    Farag A; Abass W; Qassem H · Journal of medicine and life · 2024
    Cohort study50 participantsInflammation forGlutathione
  20. Efficacy of Vitamin C as Glucocorticoid Substitute for Reducing Pain and Inflammation After Total Hip Arthroplasty: A Randomized Controlled Trial.
    Jiang W; Xu H; Jiang X; Zhan Y; Ju Y; Xie J; Huang Z; Huang Q; Pei F · The Journal of bone and joint surgery. American volume · 2025
    Randomized trial107 participantsInflammation forVitamin C