Studies

Explore research connecting ingredients and health goals.

12 ingredient–goal connections

GoalReported findings
SupportiveMixedNo effectAdverseUnclassified

Testosterone SupportandVitamin D

56published studies

SupportiveNot rated

Some observational studies link higher vitamin D levels with higher testosterone in men, and genetic and laboratory research suggests a possible biological connection. However, associations between blood levels do not establish that taking vitamin D raises testosterone. Randomized trials in healthy and vitamin D-deficient men, along with research in male infertility, generally show no clear increase in testosterone despite improved vitamin D status.

Some findings suggest effects on the fraction of testosterone available to tissues, but these are inconsistent and do not establish a reliable hormone benefit. Improvements in sperm movement or other reproductive measures also should not be interpreted as evidence of increased testosterone. Research in women with polycystic ovary syndrome addresses a different problem: vitamin D sometimes reduces elevated androgen levels rather than raising them, and those results are also mixed. Overall, the supplied evidence supports neither a dependable testosterone boost nor the assumption that correcting low vitamin D will normalize low testosterone.

56 linked studies · 26 sampled for detail · Sep 27, 2026

Study types

  • Cross-sectional study14
  • Randomized trial11
  • Meta-analysis7
  • Systematic review6
  • Narrative review5
  • Observational study4
  • Single-arm trial4
  • Case-control study2
  • Other2
  • Cohort study1

Published by year

  • 12010
  • 12011
  • 22012
  • 02013
  • 32014
  • 22015
  • 22016
  • 42017
  • 42018
  • 22019
  • 42020
  • 72021
  • 72022
  • 42023
  • 62024
  • 42025
  • 32026

Findings over time

Numbers above bars show study counts.

20263 studies

  • Supportive0
  • Mixed1
  • No effect2
  • Adverse0
  • Unclassified0

Population over time

Reported participants by publication year. Select a year to see the total and reporting coverage.

— Participant count not reported.

20252,725 reported participants

Counts reported by 2 of 4 studies. 2 without a reported count.

Totals sum reported counts across studies and reviews; participants may overlap between sources.

Explore this goal

Showing 5 top-ranked studies for Vitamin D and Testosterone Support.

Top studies

Vitamin D · Testosterone SupportHighest ranked first
  1. Effect of Two Different Doses of Vitamin D Supplementation on Metabolic Profiles of Insulin-Resistant Patients with Polycystic Ovary Syndrome.
    2018Randomized trial90 participants

    Nutrients

    Finding Compared with low-dose vitamin D and placebo, 4000 IU reduced total testosterone, free androgen index, hirsutism, and hs-CRP in insulin-resistant women with PCOS.

    SupportiveView source for Effect of Two Different Doses of Vitamin D Supplementation on Metabolic Profiles of Insulin-Resistant Patients with Polycystic Ovary Syndrome. (opens in a new tab)
  2. Androgens and hirsutism score of overweight women with polycystic ovary syndrome improved after vitamin D treatment: A randomized placebo controlled clinical trial.
    2021Randomized trial60 participants

    Clinical nutrition (Edinburgh, Scotland)

    Finding After 12 weeks, total testosterone and free androgen index decreased significantly, while sex hormone-binding globulin increased significantly.

    SupportiveView source for Androgens and hirsutism score of overweight women with polycystic ovary syndrome improved after vitamin D treatment: A randomized placebo controlled clinical trial. (opens in a new tab)
  3. Association between plasma 25-OH vitamin D and testosterone levels in men.
    2012Case-control study1,362 participants

    Clinical endocrinology

    Finding Higher plasma 25(OH)D was associated with higher total and free testosterone levels in these men; the cross-sectional design cannot show that vitamin D raises testosterone.

    SupportiveView source for Association between plasma 25-OH vitamin D and testosterone levels in men. (opens in a new tab)
  4. Causal Link Between Vitamin D and Total Testosterone in Men: A Mendelian Randomization Analysis.
    2020Other4,254 participants

    The Journal of clinical endocrinology and metabolism

    Finding Lower 25(OH)D was associated with lower total testosterone, and the MR estimate for genetically determined higher 25(OH)D on total testosterone was 0.12 (95% CI 0.02-0.22).

    SupportiveView source for Causal Link Between Vitamin D and Total Testosterone in Men: A Mendelian Randomization Analysis. (opens in a new tab)
  5. Associations of vitamin D status and vitamin D-related polymorphisms with sex hormones in older men.
    2017Cohort study643 participants

    The Journal of steroid biochemistry and molecular biology

    Finding Higher serum 25(OH)D was associated with higher total and bioavailable testosterone in the cohort.

    SupportiveView source for Associations of vitamin D status and vitamin D-related polymorphisms with sex hormones in older men. (opens in a new tab)

Counts reflect published studies in our database, not the strength of a benefit. A study may appear in more than one connection.