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UltraClear Plus pH Vanilla Flavor

Metagenics
4.8
★ ★ ★ ★ ★
(23 ratings)
Alanine 235 mg
Phosphorus 300 mg
Lysine 505 mg
Sulfur 20 mg
Cysteine 85 mg
Green Tea 25 mg
Product Image
Score66
A broad nutrition shake with protein, glycine, lysine, hair-relevant vitamins, and meaningful minerals. High cost, carbohydrate, low vitamin D, and modest cysteine make it an inefficient dedicated hair product.
How scoring works
Quantity:2 lb(s) • (21 servings)
Goals:
Hair Health

Score 66

A broad nutrition shake with protein, glycine, lysine, hair-relevant vitamins, and meaningful minerals. High cost, carbohydrate, low vitamin D, and modest cysteine make it an inefficient dedicated hair product.
How scoring works
$121.95($5.80 per serving)
iHerb
$ 121.95
Pure Formulas
$ 121.95
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Analysis

Ten grams of protein, 1.6 g glycine, 505 mg lysine, methionine, cysteine, threonine, and alanine provide structural amino acids relevant to hair. Zinc, copper, biotin, vitamin C, active folate, methylcobalamin, and other vitamins add useful cofactor coverage.

Magnesium, potassium, calcium, and phosphorus make the powder nutritionally substantial, but the vitamin D amount is very low. Cysteine is present at only 85 mg, so the hair-support profile depends more on the overall protein and nutrient blend than on a strong sulfur-amino-acid dose.

The shake requires mixing, adds 21 g carbohydrate, and provides only a limited number of premium servings. It fits someone using a practitioner-guided nutrition plan, not a shopper who wants a compact and economical hair supplement.

Who is it for
  • Adults using a structured nutrition shake
  • Users seeking protein plus hair-related nutrients
  • People who need broad fortified nutrition
Best for
  • Protein and amino-acid support
  • Broad hair-related nutrient coverage
  • Practitioner-guided nutritional programs

Pros

  • Provides 10 g protein
  • Strong glycine and useful lysine amounts
  • Uses methylfolate and methylcobalamin
  • Meaningful magnesium and potassium
  • Includes zinc, copper, biotin, and vitamin C

Cons

  • Premium serving cost
  • Adds 21 g carbohydrate
  • Vitamin D amount is very low
  • Cysteine amount is modest
  • Only twenty-one servings

Warnings

  • Potassium and magnesium amounts require review in people with impaired kidney function.
  • Chromium may lower blood glucose and can add to diabetes medicines.
  • Retinyl palmitate is preformed vitamin A and needs attention during pregnancy and with liver conditions.
  • The formula is a substantial nutrition powder, so it should be counted toward daily calories, carbohydrate, and protein rather than added without adjustment.

Nutrient quality

74 High impact

Methylfolate, methylcobalamin, citrate minerals, and lysine hydrochloride support good form quality. Protein, glycine, lysine, and several minerals are useful, while cysteine, green tea, and vitamin D are modest.

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Ingredient transparency

83 Highest impact

Every listed active has a specific amount. Serving count is available, but complete preparation and daily use directions are not supplied.

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Customer satisfaction

65 High impact

The aggregate rating is strong and supported by limited rating volume. No specific feedback was supplied to judge repeated complaints or fit with the intended use.

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Value for money

35 Lower impact

The broad formula does not fully justify the very high asking price. Each serving is costly relative to the depth of its specialty actives.

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Goals

Impact
High effect
B Goal FitB- Strength of SupportB CoverageB+ Formula Quality
Biotin · 135 mcgVitamin D · 0.8 mcgZinc · 10 mgIron · 0.5 mgLysine · 505 mgVitamin C · 300 mg

Complete protein, lysine, methionine, cysteine, glycine, vitamin C, zinc, and copper provide broad building blocks for hair. The protein and lysine amounts are meaningful, while several sulfur amino acids and biotin are more modest.

Micronutrients and antioxidant support complement the structural protein base. The variable powder serving makes exact daily dosing less straightforward.

Study evidence
Biotin Supportive 4 studies
Copper Adverse 4 studies
Lysine Supportive 1 study
Vitamin C Mixed 5 studies
Vitamin D Disputed 34 studies
Zinc Supportive 22 studies

Ingredients

IngredientAmount per serving
Calories
180 Calorie(s)
Total Fat
5 Gram(s)
Total Carbohydrates
21 Gram(s)
Protein
10 Gram(s)
Vitamin A (Beta-Carotene, Retinyl Palmitate)
1500 mcg
Vitamin C (Ascorbic Acid)
300 mg
Vitamin D (Cholecalciferol)
0.8 mcg
Vitamin E (D-Alpha-Tocopheryl Acetate)
28.1 mg
Thiamine (Thiamine Hydrochloride)
2 mg
Riboflavin
2 mg
Niacin (Niacinamide)
9.4 mg
Vitamin B6 (Pyridoxine Hydrochloride)
3.4 mg
Metafolin (Folate)
135 mcg DFE
Vitamin B12 (Methylcobalamin)
3.6 mcg
Biotin
135 mcg
Pantothenic Acid (Calcium D-Pantothenate)
36 mg
Calcium (Calcium Citrate, Dicalcium Phosphate)
230 mg
Iron
0.5 mg
Phosphorus (Dicalcium Phosphate, Dipotassium Phosphate)
300 mg
Iodine (Potassium Iodide)
53 mcg
Magnesium (Magnesium Citrate, Magnesium Sulfate)
230 mg
Zinc (Zinc Gluconate)
10 mg
Copper (Copper Gluconate)
1 mg
Manganese
1 mg
Chromium (Chromium Picolinate)
50 mcg
Sodium
100 mg
Potassium (Dipotassium Phosphate, Potassium Citrate)
750 mg
Glycine
1.6 Gram(s)
L-Lysine (L-Lysine Hydrochloride)
505 mg
L-Threonine
285 mg
L-Alanine
235 mg
DL-Methionine
170 mg
L-Glutamine
100 mg
L-Cysteine (L-Cysteine Hydrochloride)
85 mg
Green Tea Leaf Extract, Decaffeinated (Camellia sinensis Leaf Extract, Decaffeinated)
25 mg
Sulfate (Magnesium Sulfate)
20 mg
Gluten Free Adults 18–50
Report overview
Alanine · 235 mg OverallScore79
A- Active Ingredient Quality & BioavailabilityA- Dose, Safety & Label TransparencyD+ Value

The 235 mg L-Alanine amount provides an above-median supportive dose. L-Alanine is clearly identified and listed separately, although free-form status is not stated. Neutral value is appropriate because alanine is secondary to the broader formula.

B- Active Ingredient Quality & BioavailabilityA+ Dose, Safety & Label TransparencyF Value

Reliable dicalcium phosphate is mixed with less bone-specific dipotassium phosphate. The 300 mg amount reaches the upper end of the targeted range in an adjustable powder serving. A very high serving cost results in poor price efficiency.

B- Active Ingredient Quality & BioavailabilityB- Dose, Safety & Label TransparencyF Value

The hydrochloride form and clinically aligned lysine amount provide a sound active base. A variable powder serving is less convenient than a small scoop, while purity claims and non-active ingredient details are missing. Vitamin C and zinc add relevant support, but the very high cost per unit of lysine makes the formula poor targeted value.

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Sources

Published studies used for the product analysis and the top-ranked studies for each ingredient and goal.

  1. Causes of hair loss and the developments in hair rejuvenation.
    Rushton DH; Norris MJ; Dover R; Busuttil N · International journal of cosmetic science · 2010
    Narrative reviewHair Health forLysine
  2. The Role of Sesbania grandiflora-Derived Biotin and Bambusa arundinacea-Derived Silica Extracts in Promoting Hair, Skin, and Nail Health: A Randomized, Double-Blind, Placebo-Controlled Clinical Study.
    Patel MN; Maheshvari J; Patel N · Cureus · 2025
    Randomized trial105 participantsHair Health forBiotin
  3. Low serum biotinidase activity in children with valproic acid monotherapy.
    Schulpis KH; Karikas GA; Tjamouranis J; Regoutas S; Tsakiris S · Epilepsia · 2001
    Clinical trial125 participantsHair Health forBiotin
  4. Vitamins A, B, C, and D: A Short Review for the Dermatologist.
    Coerdt KM; Goggins CA; Khachemoune A · Alternative therapies in health and medicine · 2021
    Narrative reviewHair Health forBiotin
  5. The Infatuation With Biotin Supplementation: Is There Truth Behind Its Rising Popularity? A Comparative Analysis of Clinical Efficacy versus Social Popularity.
    Soleymani T; Lo Sicco K; Shapiro J · Journal of drugs in dermatology : JDD · 2018
    Narrative reviewHair Health forBiotin
  6. Menkes disease and response to copper histidine: An Indian case series.
    Yoganathan S; Sudhakar SV; Arunachal G; Thomas M; Subramanian A; George R; Danda S · Annals of Indian Academy of Neurology · 2022
    Case series4 participantsHair Health forCopper
  7. Trace element levels in alopecia areata.
    Bhat YJ; Manzoor S; Khan AR; Qayoom S · Indian journal of dermatology, venereology and leprology · 2009
    Case-control study100 participantsHair Health forCopper
  8. UV damage to hair and the effect of antioxidants and metal chelators.
    Millington KR; Marsh JM · International journal of cosmetic science · 2021
    In vitro / ex vivo studyHair Health forCopper
  9. Preserving fibre health: reducing oxidative stress throughout the life of the hair fibre.
    Marsh JM; Davis MG; Lucas RL; Reilman R; Styczynski PB; Li C; Mamak M; McComb DW; Williams RE; Godfrey S; Navqi KR; Chechik V · International journal of cosmetic science · 2016
    In vitro / ex vivo studyHair Health forCopper
  10. Management of hair loss associated with endocrine therapy in patients with breast cancer: an overview.
    Karatas F; Sahin S; Sever AR; Altundag K · SpringerPlus · 2016
    Narrative reviewHair Health forVitamin C
  11. Elucidating causal relationships of diet-derived circulating antioxidants and the risk of non-scarring alopecia: A Mendelian randomization study.
    Ba Y; Shen L; Peng X; Zhang Y; Wang J · Medicine · 2024
    Methods validation study201,019 participantsHair Health forVitamin C
  12. Alterations of plasma antioxidants and mitochondrial DNA mutation in hair follicles of smokers.
    Liu CS; Chen HW; Lii CK; Tsai CS; Kuo CL; Wei YH · Environmental and molecular mutagenesis · 2002
    Observational studyHair Health forVitamin C
  13. Removal of synthetic hair dye using formamidine sulfinic acid and other sulfinate precursors.
    Hawkes JA; Lewis DM; Mama J; Murray J · International journal of cosmetic science · 2026
    Methods validation studyHair Health forVitamin C
  14. A Zinc Sulphate-Resistant Acrodermatitis Enteropathica Patient with a Novel Mutation in SLC39A4 Gene.
    Kilic M; Taskesen M; Coskun T; Gürakan F; Tokatli A; Sivri HS; Dursun A; Schmitt S; Küry S · JIMD reports · 2013
    Case reportHair Health forVitamin C
  15. Increased prevalence of vitamin D deficiency in patients with alopecia areata: a systematic review and meta-analysis.
    Lee S; Kim BJ; Lee CH; Lee WS · Journal of the European Academy of Dermatology and Venereology : JEADV · 2018
    Meta-analysis2,039 participants14 studies pooledHair Health forVitamin D
  16. Intralesional vitamin D3 in treatment of alopecia areata: A randomized controlled clinical trial.
    Rashad AF; Elgamal E; Fouda I · Journal of cosmetic dermatology · 2022
    Randomized trial60 participantsHair Health forVitamin D
  17. Vitamin D and its Analogs in Treatment of Mild to Moderate Alopecia Areata: Systematic Review and Meta-Analysis.
    Alsaati AA; Kaliyadan F; Alsaadoun D; Alzakry LM; Alzabadin RA; Hakami TH; Rubaian NFB · Indian dermatology online journal · 2025
    Meta-analysisHair Health forVitamin D
  18. Topical calcipotriol vs narrowband ultraviolet B in treatment of alopecia areata: a randomized-controlled trial.
    El Taieb MA; Hegazy EM; Ibrahim HM; Osman AB; Abualhamd M · Archives of dermatological research · 2020
    Randomized trial60 participantsHair Health forVitamin D
  19. Serum 25 hydroxyvitamin D in non-scarring alopecia: A systematic review and meta-analysis.
    Chen Y; Dong X; Wang Y; Li Y; Xiong L; Li L · Journal of cosmetic dermatology · 2024
    Meta-analysis10,670 participants23 studies pooledHair Health forVitamin D
  20. The effects of minoxidil, 1% pyrithione zinc and a combination of both on hair density: a randomized controlled trial.
    Berger RS; Fu JL; Smiles KA; Turner CB; Schnell BM; Werchowski KM; Lammers KM · The British journal of dermatology · 2003
    Randomized trial200 participantsHair Health forZinc
  21. Incubatory environment of the scalp impacts pre-emergent hair to affect post-emergent hair cuticle integrity.
    Schwartz JR; Henry JP; Kerr KM; Flagler MJ; Page SH; Redman-Furey N · Journal of cosmetic dermatology · 2018
    Randomized trialHair Health forZinc
  22. A comparison of hair quality and cosmetic acceptance following the use of two anti-dandruff shampoos.
    Draelos ZD; Kenneally DC; Hodges LT; Billhimer W; Copas M; Margraf C · The journal of investigative dermatology. Symposium proceedings · 2006
    Randomized trial40 participantsHair Health forZinc
  23. BMI and levels of zinc, copper in hair, serum and urine of Turkish male patients with androgenetic alopecia.
    Ozturk P; Kurutas E; Ataseven A; Dokur N; Gumusalan Y; Gorur A; Tamer L; Inaloz S · Journal of trace elements in medicine and biology : organ of the Society for Minerals and Trace Elements (GMS) · 2015
    Case-control study216 participantsHair Health forZinc
  24. Analysis of serum zinc and copper concentrations in hair loss.
    Kil MS; Kim CW; Kim SS · Annals of dermatology · 2013
    Case-control study342 participantsHair Health forZinc