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Beet Root RED

Irwin Naturals
4.6
★ ★ ★ ★ ★
(200 ratings)
Citrulline 1500 mg
Vitamin B12 139 mcg
Protein 5 Gram(s)
Product Image
Score68
The formula combines citrulline with beet and red spinach for circulation support, but key blood-flow amounts are modest or incompletely defined. A crowded ingredient list and four-softgel serving further weaken value.
How scoring works
Quantity:60 Softgel(s) • (15 servings)
Goals:
General Health
Cardiovascular Support
Hair Health

Score 68

The formula combines citrulline with beet and red spinach for circulation support, but key blood-flow amounts are modest or incompletely defined. A crowded ingredient list and four-softgel serving further weaken value.
How scoring works
$24.99($1.66 per serving)
iHerb
$ 24.99
Pure Formulas
$ 24.99
Vitacost
$ 24.99
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Analysis

The main purpose is circulation support, led by 1,500 mg of L-citrulline with beet and red-spinach extracts. Citrulline is present at a useful maintenance amount, but it remains below common performance amounts and the plant extracts do not disclose their nitrate yield.

Flaxseed oil, pomegranate, red ginseng, cayenne, vitamin C, and methylcobalamin add nutritional breadth. Many of these additions are supplied at modest amounts, so the crowded formula does not provide the depth expected from a focused cardiovascular or general-health supplement.

Most active ingredients have separate amounts, which makes the formula easier to assess. Even so, the four-softgel full serving is cumbersome, and the limited citrulline and undisclosed nitrate content make the serving value difficult to justify.

Who is it for
  • Adults seeking mild daily circulation support
  • Users who prefer softgels over drink powders
  • People who value separately disclosed active amounts
Best for
  • Entry-level citrulline support
  • Combining citrulline with beet and red-spinach extracts
  • A broad circulation-oriented ingredient mix

Pros

  • Provides 1,500 mg of free-form L-citrulline
  • Uses methylcobalamin as the vitamin B12 form
  • Discloses separate amounts for most active ingredients
  • Combines several ingredients aimed at blood flow

Cons

  • Citrulline is below common performance amounts
  • Beet and red-spinach extracts do not disclose nitrate yield
  • Several secondary ingredients are present at modest amounts
  • The full serving requires four softgels and offers weak value

Warnings

  • Citrulline, beet, and red spinach may add to the effects of nitrates or blood-pressure medicines and could increase lightheadedness in susceptible users.
  • The 6 mg BioPerine complex can change how some medicines are absorbed or metabolized; people taking prescription medicines should check the specific combination with a pharmacist.
  • Cayenne and the multi-softgel oil serving may aggravate heartburn or stomach discomfort in sensitive users.

Nutrient quality

72 High impact

Methylcobalamin is a favorable vitamin B12 form, and free-form citrulline fits the circulation focus. Citrulline remains modest for performance use, while several plant extracts lack standardized active amounts or appear lightly dosed.

Ingredient transparency

81 Highest impact

All listed active ingredients have separate amounts and no proprietary blend hides the formula. Branded extracts and variable serving guidance remain harder to interpret, while complete softgel excipients are not supplied.

Customer satisfaction

74 High impact

The high average rating and useful review count suggest broad customer satisfaction. No review excerpts show recurring complaints or experiences tied to circulation support, so those conclusions remain uncertain.

Value for money

41 Lower impact

The formula includes several useful actives, but the core citrulline amount and lightly dosed extracts do not fully justify the premium. Prior ingredient comparisons also indicate poor value for both citrulline and vitamin B12.

Report analysis

Goals

Impact
Moderate effect
C Goal FitC Strength of SupportC CoverageC+ Formula Quality
Vitamin B12 · 139 mcgVitamin C · 90 mg

Methylcobalamin, vitamin C, vitamin B6, citrulline, flaxseed oil, and beet-related extracts offer a mix of foundational and circulation-oriented support. B12 uses a favorable active form, while citrulline provides the main performance dose.

The beet and red-spinach extracts are modest and do not disclose nitrate yield, making the circulation effect uncertain. A variable two- or four-softgel serving also makes the dose pattern less straightforward.

Study evidence
Vitamin B12 Adverse 66 studies
Vitamin C Supportive 56 studies
Cardiovascular Support
Impact
Moderate effect
B- Goal FitC- Strength of SupportC CoverageC- Formula Quality
Vitamin B12 · 139 mcgVitamin B6 · 10 mgVitamin C · 90 mgCitrulline · 1500 mg

L-citrulline, beet extract, and red spinach target nitric oxide and blood flow, while flaxseed oil and pomegranate add secondary support. The citrulline amount is below common vascular research doses, and nitrate content is not disclosed for the plant extracts.

Named extracts and separate amounts improve transparency, but many additions are too small to create a balanced cardiovascular formula. Citrulline may add to the blood-pressure-lowering effects of nitrates or antihypertensive medicines and can cause lightheadedness in susceptible users.

Study evidence
Citrulline Supportive 33 studies
Hair Health
Impact
Moderate effect
D- Goal FitB- Strength of SupportD CoverageD- Formula Quality
Vitamin C · 90 mg

The formula may support general circulation and nutrient status. No structural or deficiency-focused hair active makes the connection indirect.

Ingredient amounts are mostly transparent. Circulation ingredients provide weakly supported breadth and substantial goal mismatch.

Study evidence
Vitamin B12 Disputed 17 studies
Vitamin C Mixed 5 studies

Ingredients

IngredientAmount per serving
Calories
45 Calorie(s)
Total Fat
2.5 Gram(s)
Protein
5 Gram(s)
Vitamin C (Ascorbic Acid)
90 mg
Vitamin B6 (Pyridoxine Hydrochloride)
10 mg
Vitamin B12 (Methylcobalamin)
139 mcg
Sodium
10 mg
Flaxseed Oil
1800 mg
L-Citrulline
1500 mg
Medium Chain Triglyceride Oil
1000 mg
Sabeet (Beet root extract)
150 mg
Cayenne, Powder
60 mg
Pomegranate extract
50 mg
Oxystorm (Red Spinach Leaf Extract)
20 mg
Red Ginseng Root Extract (Panax ginseng Root Extract)
20 mg
BioPerine Complex
6 mg
Adults 18–50
Report overview
Citrulline · 1500 mg OverallScore62
B- Active Ingredient Quality & BioavailabilityA- Dose, Safety & Label TransparencyF Value

The formula clearly provides 1,500 mg of free-form L-citrulline, a useful maintenance amount that remains below the usual performance range. No fermentation, branded sourcing, grade, or purity-testing marker is provided. The multi-ingredient softgel carries a high cost relative to its citrulline content.

A- Active Ingredient Quality & BioavailabilityF Dose, Safety & Label TransparencyF Value

Methylcobalamin provides a clearly identified bioactive B12 form. The 139 mcg serving is better aligned with basic maintenance than higher needs. The multi-softgel serving is cumbersome, and cost efficiency is very poor for the B12 supplied.

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Sources

Published studies used for the product analysis and the top-ranked studies for each ingredient and goal.

  1. Does l-citrulline supplementation and watermelon intake reduce blood pressure in middle-aged and older adults? A systematic review and meta-analysis of randomized controlled trials.
    Luo P; Chen J; Liu K; Zhang J · Clinical nutrition ESPEN · 2025
    Meta-analysis415 participants15 studies pooledCardiovascular Support forCitrulline
  2. Oral citrulline supplementation in pregnancies with preeclampsia: a multicenter, randomized, double-blind clinical trial.
    Winer N; Misbert E; Masson D; Girault A; Alexandre-Gouabau MC; Ducarme G; Dochez V; Thubert T; Boivin M; Ferchaud-Roucher V; Péré M; Darmaun D · The American journal of clinical nutrition · 2025
    Randomized trial115 participantsCardiovascular Support forCitrulline
  3. Effects of l-citrulline supplementation and watermelon consumption on longer-term and postprandial vascular function and cardiometabolic risk markers: a meta-analysis of randomised controlled trials in adults.
    Smeets ETHC; Mensink RP; Joris PJ · The British journal of nutrition · 2026
    Meta-analysis17 studies pooledCardiovascular Support forCitrulline
  4. Micronutrient Supplementation to Reduce Cardiovascular Risk.
    An P; Wan S; Luo Y; Luo J; Zhang X; Zhou S; Xu T; He J; Mechanick JI; Wu WC; Ren F; Liu S · Journal of the American College of Cardiology · 2022
    Meta-analysis883,627 participants884 studies pooledCardiovascular Support forCitrulline
  5. l-Citrulline supplementation improves O2 uptake kinetics and high-intensity exercise performance in humans.
    Bailey SJ; Blackwell JR; Lord T; Vanhatalo A; Winyard PG; Jones AM · Journal of applied physiology (Bethesda, Md. : 1985) · 2016
    Randomized trial10 participantsCardiovascular Support forCitrulline
  6. Effects of L-Citrulline Supplementation on Endothelial Function and Blood Pressure in Hypertensive Postmenopausal Women.
    Maharaj A; Fischer SM; Dillon KN; Kang Y; Martinez MA; Figueroa A · Nutrients · 2022
    Randomized trial25 participantsCardiovascular Support forCitrulline
  7. Short-term effects of L-citrulline supplementation on arterial stiffness in middle-aged men.
    Ochiai M; Hayashi T; Morita M; Ina K; Maeda M; Watanabe F; Morishita K · International journal of cardiology · 2012
    Randomized trial15 participantsCardiovascular Support forCitrulline
  8. Oral Vitamin B12 versus Placebo for the Prevention of Chemotherapy-Induced Peripheral Neuropathy in Gynecological Cancer Patients: A Randomized, Double-Blind, Placebo-Controlled Trial.
    Insin P; Chaiwongsa T; Prueksaritanond N · Asian Pacific journal of cancer prevention : APJCP · 2026
    Randomized trial40 participantsGeneral Health forVitamin B12
  9. Vitamin B12 Supplementation in Diabetic Neuropathy: A 1-Year, Randomized, Double-Blind, Placebo-Controlled Trial.
    Didangelos T; Karlafti E; Kotzakioulafi E; Margariti E; Giannoulaki P; Batanis G; Tesfaye S; Kantartzis K · Nutrients · 2021
    Randomized trial90 participantsGeneral Health forVitamin B12
  10. A single-center randomized controlled trial of local methylcobalamin injection for subacute herpetic neuralgia.
    Xu G; Lv ZW; Feng Y; Tang WZ; Xu GX · Pain medicine (Malden, Mass.) · 2014
    Randomized trial98 participantsGeneral Health forVitamin B12
  11. Local Injection of Methylcobalamin Combined with Lidocaine for Acute Herpetic Neuralgia.
    Xǔ G; Xu S; Tang WZ; Xú G; Cheng C; Xu J · Pain medicine (Malden, Mass.) · 2017
    Randomized trial204 participantsGeneral Health forVitamin B12
  12. The Effect of Vitamin B12 and Folic Acid Supplementation on Serum Homocysteine, Anemia Status and Quality of Life of Patients with Multiple Sclerosis.
    Nozari E; Ghavamzadeh S; Razazian N · Clinical nutrition research · 2022
    Clinical trial50 participantsGeneral Health forVitamin B12
  13. Dietary intake and blood concentrations of antioxidants and the risk of cardiovascular disease, total cancer, and all-cause mortality: a systematic review and dose-response meta-analysis of prospective studies.
    Aune D; Keum N; Giovannucci E; Fadnes LT; Boffetta P; Greenwood DC; Tonstad S; Vatten LJ; Riboli E; Norat T · The American journal of clinical nutrition · 2019
    Meta-analysis69 studies pooledGeneral Health forVitamin C
  14. Scientific Opinion on the substantiation of a health claim related to vitamin C and increasing non haem iron absorption pursuant to Article 14 of Regulation (EC) No 1924/2006.
    EFSA Panel on Dietetic Products, Nutrition and Allergies (NDA) · EFSA journal. European Food Safety Authority · 2026
    Guideline / consensusGeneral Health forVitamin C
  15. Vitamin C Depletion and All-Cause Mortality in Renal Transplant Recipients.
    Sotomayor CG; Eisenga MF; Gomes Neto AW; Ozyilmaz A; Gans ROB; Jong WHA; Zelle DM; Berger SP; Gaillard CAJM; Navis GJ; Bakker SJ · Nutrients · 2018
    Cohort study598 participantsGeneral Health forVitamin C
  16. Associations of Serum Biomarkers of Fruit and Vegetable Intake With the Risk of Cause-Specific Mortality and All-Cause Mortality: A National Prospective Cohort Study.
    Pu L; Zhang R; Wang X; Zhao T; Sun H; Han L · Frontiers in nutrition · 2022
    Cohort study12,530 participantsGeneral Health forVitamin C
  17. Relation between plasma ascorbic acid and mortality in men and women in EPIC-Norfolk prospective study: a prospective population study. European Prospective Investigation into Cancer and Nutrition.
    Khaw KT; Bingham S; Welch A; Luben R; Wareham N; Oakes S; Day N · Lancet (London, England) · 2001
    Cohort study19,496 participantsGeneral Health forVitamin C
  18. Quantitative Analysis of Selected Circulating Hematological Biomarkers, Essential Minerals, Vitamins, and Thyroid Hormones in Females Affected by Hair Loss.
    Al-Fawaeir S; Al-Odat I · Diseases (Basel, Switzerland) · 2025
    Case-control study200 participantsHair Health forVitamin B12
  19. Factors Associated with Premature Hair Graying in a Young Indian Population.
    Chakrabarty S; Krishnappa PG; Gowda DG; Hiremath J · International journal of trichology · 2016
    Case-control study74 participantsHair Health forVitamin B12
  20. Risk Factors for Pediatric Alopecia Areata: Clinical and Biochemical Findings from a Case - Control Study.
    İritaş SY · Dermatology practical & conceptual · 2026
    Case-control study600 participantsHair Health forVitamin B12
  21. Hair Loss After Laparoscopic Sleeve Gastrectomy.
    Katsogridaki G; Tzovaras G; Sioka E; Perivoliotis K; Zachari E; Magouliotis D; Tasiopoulou V; Chatedaki C; Zacharoulis D · Obesity surgery · 2019
    Cohort study50 participantsHair Health forVitamin B12
  22. Demographic Characteristics and Association of Serum Vitamin B12, Ferritin and Thyroid Function with Premature Canities in Indian Patients from an Urban Skin Clinic of North India: A Retrospective Analysis of 71 Cases.
    Sonthalia S; Priya A; Tobin DJ · Indian journal of dermatology · 2022
    Cross-sectional study71 participantsHair Health forVitamin B12
  23. Management of hair loss associated with endocrine therapy in patients with breast cancer: an overview.
    Karatas F; Sahin S; Sever AR; Altundag K · SpringerPlus · 2016
    Narrative reviewHair Health forVitamin C
  24. Elucidating causal relationships of diet-derived circulating antioxidants and the risk of non-scarring alopecia: A Mendelian randomization study.
    Ba Y; Shen L; Peng X; Zhang Y; Wang J · Medicine · 2024
    Methods validation study201,019 participantsHair Health forVitamin C
  25. Alterations of plasma antioxidants and mitochondrial DNA mutation in hair follicles of smokers.
    Liu CS; Chen HW; Lii CK; Tsai CS; Kuo CL; Wei YH · Environmental and molecular mutagenesis · 2002
    Observational studyHair Health forVitamin C
  26. Removal of synthetic hair dye using formamidine sulfinic acid and other sulfinate precursors.
    Hawkes JA; Lewis DM; Mama J; Murray J · International journal of cosmetic science · 2026
    Methods validation studyHair Health forVitamin C
  27. A Zinc Sulphate-Resistant Acrodermatitis Enteropathica Patient with a Novel Mutation in SLC39A4 Gene.
    Kilic M; Taskesen M; Coskun T; Gürakan F; Tokatli A; Sivri HS; Dursun A; Schmitt S; Küry S · JIMD reports · 2013
    Case reportHair Health forVitamin C