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L-Glutamine Powder

Bluebonnet
4.7
★ ★ ★ ★ ★
(232 ratings)
Glutamine 5000 mg
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Score82
A practical gram-level powder avoids pill burden, with missing purity and micronization details as the main trade-offs.
How scoring works
Quantity:8 Ounce(s) • (45 servings)
Goals:
Digestive Health
Immunity

Score 82

A practical gram-level powder avoids pill burden, with missing purity and micronization details as the main trade-offs.
How scoring works
$31.16($0.69 per serving)
Daily Vita
$ 31.96
iHerb
$ 31.96
Vitacost
$ 31.96
Amazon
$ 31.16
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Analysis

A 5000 mg serving reaches a meaningful gram-level intake that may support intestinal-cell fuel during physiological stress. The focused powder is easy to scale and contains no competing active ingredients.

The supplied data do not identify a premium purity grade or micronized processing. Those omissions do not change the disclosed amount but limit comparison with higher-specification powders.

The 45-serving package is practical but shorter than some bulk powders. The disclosed serving offers competitive dose efficiency. The product supports one gut-barrier and metabolic pathway rather than fiber, enzymes, motility, or microbiome diversity.

Who is it for
  • Adults seeking gram-level L-glutamine
  • People who prefer powders to multiple capsules
  • Users focused on a single amino acid
Best for
  • Gut-barrier support during physiological stress
  • Flexible gram-level dosing
  • Mixing into water or another drink

Pros

  • 5000 mg serving
  • Single-ingredient powder
  • Easy to scale

Cons

  • No premium purity grade
  • Micronization is not stated
  • No premium grade is stated.

Nutrient quality

90 Highest impact

Clear L-glutamine labeling and the powder format support straightforward use. The powder provides a substantial targeted glutamine serving, while the substantial amount remains within common supplemental use.

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Ingredient transparency

83 Highest impact

The active amount is disclosed without a hidden blend. Intake directions and inactive ingredients are not supplied.

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Customer satisfaction

64 Moderate impact

The supplied average rating is strong and comes from a limited rating pool. No firsthand experiences or recurring complaint details were provided, so consistency remains uncertain.

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Value for money

85 Highest impact

A substantial powder serving provides good value at a moderate cost. The simple formula remains competitive for targeted use.

.
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Goals

Digestive Health
Digestive Health
Impact
Highest effect
A- Goal FitA+ Strength of SupportC- CoverageA+ Formula Quality
Glutamine · 5000 mg

L-glutamine supplies fuel used by intestinal cells and may support barrier integrity during physiological stress. Evidence for routine use in otherwise healthy people with vague digestive symptoms is less certain.

The powder provides a meaningful 5 g amount with full single-ingredient disclosure. The focused design offers strong barrier-support depth but no fiber, enzyme, microbiome, or motility pathway.

Study evidence
Glutamine Supportive 37 studies
Immunity
Immunity
Impact
High effect
C+ Goal FitA- Strength of SupportC CoverageA+ Formula Quality

Glutamine fuels rapidly dividing immune cells and helps maintain the gut barrier, giving it a relevant supportive role. The powder supplies a substantial and fully disclosed amount.

Benefits are most relevant during physiological stress or inadequate intake rather than as broad everyday immune coverage. The standard form is appropriate, though no premium grade or micronization detail is provided.

Study evidence
Glutamine Supportive 36 studies

Ingredients

IngredientAmount per serving
L-Glutamine, Powder
5000 mg
Gluten Free Adults 18–50 Vegan Kosher Dairy Free Sugar Free Vegetarian
Report overview
Glutamine · 5000 mg OverallScore83
C Active Ingredient Quality & BioavailabilityA+ Dose, Safety & Label TransparencyA- Value

The single-ingredient powder provides a well-disclosed amount suited to meaningful glutamine support. One teaspoon keeps daily use simple, and the cost efficiency is competitive for the amount supplied. The standard L-form is appropriate, though no premium grade or micronization claim is stated.

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Loading alternative details
78 Performance

L-Glutamine Powder

DaVinci Laboratories Of Vermont
<p>Its label clearly provides 5000 mg of L-Glutamine, making it a more clearly defined glutamine option. Compared with the original, its ingredient and goal alignment is stronger, although the input does not provide independent testing or absorption evidence.</p>
80 Performance

Theracurmin & L-Glutamine

Natural Factors CurcuminRich
<p>Its label clearly provides 5000 mg of L-Glutamine, Micronized, making it a more clearly defined glutamine option. Compared with the original, its ingredient and goal alignment is stronger, although the input does not provide independent testing or absorption evidence.</p>
71 Performance

IntestiNew

Renew Life
<p>Its label clearly provides 5000 mg of L-Glutamine, making it a more clearly defined glutamine option. Compared with the original, its ingredient and goal alignment is stronger, although the input does not provide independent testing or absorption evidence.</p>
84 Budget

Glutamine Pure Powder 5000 mg (5 g)

Country Life
<p>Its label clearly provides 5000 mg of L-Glutamine, preserving relevant glutamine coverage. Compared with the original, it lowers the serving cost, although the input does not provide independent testing or absorption evidence.</p>
83 Budget

Micronized L-Glutamine 1000 mg

Natural Factors
<p>Its label clearly provides 1000 mg of L-Glutamine, Micronized, preserving relevant glutamine coverage. Compared with the original, it lowers the serving cost, although the input does not provide independent testing or absorption evidence.</p>
80 Budget

L-Glutamine 1000 mg

Solgar
<p>Its label clearly provides 2000 mg of L-Glutamine, preserving relevant glutamine coverage. Compared with the original, it lowers the serving cost, although the input does not provide independent testing or absorption evidence.</p>
84 Value

L-Glutamine Pure Powder

Best Naturals
<p>Its label clearly provides 5000 mg of L-Glutamine, keeping the formula relevant to glutamine. Compared with the original, the lower serving cost and ingredient detail create a useful quality-to-cost balance, although the input does not provide independent testing or absorption evidence.</p>
84 Value

Glutamine 300

PS ProSupps
<p>Its label clearly provides 4500 mg of L-Glutamine, keeping the formula relevant to glutamine. Compared with the original, the lower serving cost and ingredient detail create a useful quality-to-cost balance, although the input does not provide independent testing or absorption evidence.</p>
82 Value

L-Glutamine

Jarrow Formulas
<p>Its label clearly provides 1000 mg of L-Glutamine, keeping the formula relevant to glutamine. Compared with the original, the lower serving cost and ingredient detail create a useful quality-to-cost balance, although the input does not provide independent testing or absorption evidence.</p>
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Sources

Published studies used for the product analysis and the top-ranked studies for each ingredient and goal.

  1. Effect of perioperative glutamine-enriched nutritional support on patients with colorectal cancer: A systematic review and meta-analysis.
    Huang Y; Yang XZ; Qin SH; Zhang T; Xie M; Wang JW · World journal of gastrointestinal surgery · 2026
    Meta-analysis1,643 participants27 studies pooledDigestive Health Immunity forGlutamine
  2. Glutamine prevents diarrhea in colorectal cancer patients undergoing chemotherapy or chemoradiotherapy: a meta-analysis.
    Chen L; Wang D; Meng C; Sun H; Li R; Miao G; Liu P · BMC gastroenterology · 2025
    Meta-analysis311 participants5 studies pooledDigestive Health forGlutamine
  3. Glutamine supplementation reduces markers of intestinal permeability during running in the heat in a dose-dependent manner.
    Pugh JN; Sage S; Hutson M; Doran DA; Fleming SC; Highton J; Morton JP; Close GL · European journal of applied physiology · 2018
    Randomized trial10 participantsDigestive Health forGlutamine
  4. Effect of glutamine supplementation on diarrhea, interleukin-8 and secretory immunoglobulin A in children with acute diarrhea.
    Yalçin SS; Yurdakök K; Tezcan I; Oner L · Journal of pediatric gastroenterology and nutrition · 2004
    Randomized trial128 participantsDigestive Health forGlutamine
  5. Improvement of intestinal permeability with alanyl-glutamine in HIV patients: a randomized, double blinded, placebo-controlled clinical trial.
    Leite RD; Lima NL; Leite CA; Farhat CK; Guerrant RL; Lima AA · Arquivos de gastroenterologia · 2013
    Randomized trial46 participantsDigestive Health forGlutamine
  6. Meta-analysis of Glutamine on Immune Function and Post-Operative Complications of Patients With Colorectal Cancer.
    Yang T; Yan X; Cao Y; Bao T; Li G; Gu S; Xiong K; Xiao T · Frontiers in nutrition · 2021
    Meta-analysis2,201 participants31 studies pooledImmunity forGlutamine
  7. Efficacy of Glutamine in Treating Severe Acute Pancreatitis: A Systematic Review and Meta-Analysis.
    Dong S; Zhao Z; Li X; Chen Z; Jiang W; Zhou W · Frontiers in nutrition · 2023
    Meta-analysis1,201 participants30 studies pooledImmunity forGlutamine
  8. Decreased mortality and infectious morbidity in adult burn patients given enteral glutamine supplements: a prospective, controlled, randomized clinical trial.
    Garrel D; Patenaude J; Nedelec B; Samson L; Dorais J; Champoux J; D'Elia M; Bernier J · Critical care medicine · 2003
    Randomized trial45 participantsImmunity forGlutamine
  9. Glutamine administration reduces Gram-negative bacteremia in severely burned patients: a prospective, randomized, double-blind trial versus isonitrogenous control.
    Wischmeyer PE; Lynch J; Liedel J; Wolfson R; Riehm J; Gottlieb L; Kahana M · Critical care medicine · 2001
    Randomized trial26 participantsImmunity forGlutamine