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L-Glutamine Powder

DaVinci Laboratories Of Vermont
4.9
★ ★ ★ ★ ★
(59 ratings)
Glutamine 5000 mg
Product Image
Score78
A clearly dosed 5 g powder with easy high-intake use, balanced by limited quality detail and only moderate value.
How scoring works
Quantity:150 Gram(s) • (30 servings)
Goals:
Digestive Health
Immunity

Score 78

A clearly dosed 5 g powder with easy high-intake use, balanced by limited quality detail and only moderate value.
How scoring works
$45.64($1.52 per serving)
Pure Formulas
$ 45.64
iHerb
$ 45.64
iHerb
$ 45.64
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Analysis

One serving supplies 5 g of L-glutamine, providing a full amount for focused use. The powder avoids a capsule burden and allows smaller servings to be measured when needed.

The single active and its amount are clearly disclosed without a blend. Micronized processing and a premium purity grade are not stated, leaving source and mixing details limited.

Cost efficiency falls near the favorable middle range rather than matching the strongest powder values. It suits people who want a full serving and favor simple powder over multiple capsules.

Who is it for
  • People seeking a full multi-gram amount
  • People who prefer powder
Best for
  • Focused 5 g routines
  • Users avoiding capsule burden

Pros

  • Full 5 g serving
  • No capsule burden
  • Simple single-ingredient formula

Cons

  • No premium purity grade is stated
  • Micronized processing is not claimed
  • Value is moderate for a powder

Warnings

  • A 5 g serving may cause digestive discomfort in sensitive users; a smaller first serving can help gauge tolerance.

Nutrient quality

93 Highest impact

The expected L-isomer is clear, but no premium purity or micronized-processing claim is supplied; the powder provides a full targeted amount in one serving. The disclosed glutamine amount is not unnecessarily aggressive; the amount fits digestive and general glutamine support well; the single-active formula contains no filler ingredients.

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Ingredient transparency

77 High impact

Every listed active has a specific amount; no proprietary blend hides key doses. L-glutamine is clearly named, while purity and processing details are absent; serving directions and inactive ingredients are not supplied.

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Customer satisfaction

67 High impact

The supplied aggregate average is exceptionally favorable, though no individual feedback is available; the rating sample is moderate, but no individual feedback is supplied. Detailed feedback is absent, so repeated complaints cannot be assessed; real-world fit with the intended purpose remains uncertain.

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Value for money

72 High impact

A full serving partly supports the premium price; the serving is expensive compared with many pure glutamine powders. The single-active formula contains no filler ingredients; lower-cost powders provide similar dose quality.

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Goals

Digestive Health
Impact
Highest effect
B+ Goal FitA Strength of SupportD+ CoverageA+ Formula Quality
Glutamine · 5000 mg

A full serving of L-glutamine offers focused nutritional support for intestinal cells and gut-barrier maintenance. The powder provides a material amount with complete dose disclosure and no competing actives.

Its strength is depth rather than breadth, so it does not directly address regularity, enzyme activity, or the microbiome. People seeking targeted glutamine support get a coherent formula, while those with several digestive concerns may need broader coverage.

Study evidence
Glutamine Supportive 37 studies
Immunity
Impact
High effect
C- Goal FitA+ Strength of SupportC- CoverageA+ Formula Quality

Glutamine fuels rapidly dividing intestinal and immune cells and may support gut-barrier integrity during physiological stress. The disclosed powder amount is substantial and easy to assess.

Evidence for routine immune benefits in healthy, well-nourished people is less consistent than evidence for vitamin C, vitamin D, or zinc. The single-ingredient formula is best viewed as targeted gut and stress support rather than comprehensive immunity support.

Study evidence
Glutamine Supportive 36 studies

Ingredients

IngredientAmount per serving
L-Glutamine
5000 mg
Gluten Free Adults 18–50 Vegetarian
Report overview
Glutamine · 5000 mg OverallScore80
C Active Ingredient Quality & BioavailabilityA+ Dose, Safety & Label TransparencyB- Value

A full glutamine amount in one measured serving aligns well with targeted use. The formula is simple and clearly dosed, though micronized processing is not claimed. Cost efficiency sits near the upper edge of the favorable middle tier.

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Sources

Published studies used for the product analysis and the top-ranked studies for each ingredient and goal.

  1. Glutamine supplementation reduces markers of intestinal permeability during running in the heat in a dose-dependent manner.
    Pugh JN; Sage S; Hutson M; Doran DA; Fleming SC; Highton J; Morton JP; Close GL · European journal of applied physiology · 2018
    Randomized trial10 participantsDigestive Health forGlutamine
  2. Glutamine for chemotherapy induced diarrhea: a meta-analysis.
    Sun J; Wang H; Hu H · Asia Pacific journal of clinical nutrition · 2012
    Meta-analysis298 participants8 studies pooledDigestive Health forGlutamine
  3. Treatment of acute diarrhea with oral rehydration solutions containing glutamine.
    Ribeiro Júnior H; Ribeiro T; Mattos A; Palmeira C; Fernandez D; Sant'Ana I; Rodrigues I; Bendicho MT; Fontaine O · Journal of the American College of Nutrition · 1994
    Randomized trial120 participantsDigestive Health forGlutamine
  4. Phase III double-blind study of glutamine versus placebo for the prevention of acute diarrhea in patients receiving pelvic radiation therapy.
    Kozelsky TF; Meyers GE; Sloan JA; Shanahan TG; Dick SJ; Moore RL; Engeler GP; Frank AR; McKone TK; Urias RE; Pilepich MV; Novotny PJ; Martenson JA; North Central Cancer Treatment Group · Journal of clinical oncology : official journal of the American Society of Clinical Oncology · 2003
    Randomized trial129 participantsDigestive Health forGlutamine
  5. Effect of perioperative glutamine-enriched nutritional support on patients with colorectal cancer: A systematic review and meta-analysis.
    Huang Y; Yang XZ; Qin SH; Zhang T; Xie M; Wang JW · World journal of gastrointestinal surgery · 2026
    Meta-analysis1,643 participants27 studies pooledDigestive Health Immunity forGlutamine
  6. Glutamine prevents diarrhea in colorectal cancer patients undergoing chemotherapy or chemoradiotherapy: a meta-analysis.
    Chen L; Wang D; Meng C; Sun H; Li R; Miao G; Liu P · BMC gastroenterology · 2025
    Meta-analysis311 participants5 studies pooledDigestive Health forGlutamine
  7. Effect of glutamine supplementation on diarrhea, interleukin-8 and secretory immunoglobulin A in children with acute diarrhea.
    Yalçin SS; Yurdakök K; Tezcan I; Oner L · Journal of pediatric gastroenterology and nutrition · 2004
    Randomized trial128 participantsDigestive Health forGlutamine
  8. Improvement of intestinal permeability with alanyl-glutamine in HIV patients: a randomized, double blinded, placebo-controlled clinical trial.
    Leite RD; Lima NL; Leite CA; Farhat CK; Guerrant RL; Lima AA · Arquivos de gastroenterologia · 2013
    Randomized trial46 participantsDigestive Health forGlutamine
  9. Meta-analysis of Glutamine on Immune Function and Post-Operative Complications of Patients With Colorectal Cancer.
    Yang T; Yan X; Cao Y; Bao T; Li G; Gu S; Xiong K; Xiao T · Frontiers in nutrition · 2021
    Meta-analysis2,201 participants31 studies pooledImmunity forGlutamine
  10. Efficacy of Glutamine in Treating Severe Acute Pancreatitis: A Systematic Review and Meta-Analysis.
    Dong S; Zhao Z; Li X; Chen Z; Jiang W; Zhou W · Frontiers in nutrition · 2023
    Meta-analysis1,201 participants30 studies pooledImmunity forGlutamine
  11. Decreased mortality and infectious morbidity in adult burn patients given enteral glutamine supplements: a prospective, controlled, randomized clinical trial.
    Garrel D; Patenaude J; Nedelec B; Samson L; Dorais J; Champoux J; D'Elia M; Bernier J · Critical care medicine · 2003
    Randomized trial45 participantsImmunity forGlutamine
  12. Glutamine administration reduces Gram-negative bacteremia in severely burned patients: a prospective, randomized, double-blind trial versus isonitrogenous control.
    Wischmeyer PE; Lynch J; Liedel J; Wolfson R; Riehm J; Gottlieb L; Kahana M · Critical care medicine · 2001
    Randomized trial26 participantsImmunity forGlutamine