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Silymarin Plus

Futurebiotics
4.8
★ ★ ★ ★ ★
(183 ratings)
Choline 240 mg
Milk Thistle 552 mg
Product Image
Score64
A broad liver-support formula led by milk thistle and choline. Missing silymarin potency and an undefined absorption blend weaken confidence.
How scoring works
Quantity:120 Tablet(s) • (40 servings)
Goals:
Detoxification

Score 64

A broad liver-support formula led by milk thistle and choline. Missing silymarin potency and an undefined absorption blend weaken confidence.
How scoring works
$20.97($0.52 per serving)
iHerb
$ 20.97
Vitacost
$ 22.99
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Analysis

Milk thistle seed extract and choline bitartrate form the central liver-support pair. Dandelion, inositol, and alfalfa add related but less clearly targeted support.

The milk thistle amount is large by weight, yet no silymarin percentage or active-marker yield is stated. An undefined BioAccelerators blend cannot be credited with improving absorption.

The three-tablet serving is less convenient than a concentrated capsule. The formula may suit users wanting a broad liver-oriented blend, but not those seeking verified high-potency silymarin.

Who is it for
  • Adults seeking a broad liver-oriented formula
  • Users wanting choline with milk thistle
  • People comfortable taking three tablets
Best for
  • Combined milk thistle and choline intake
  • Broad botanical liver support
  • Users who value disclosed ingredient weights

Pros

  • Large milk thistle extract weight
  • Substantial choline amount
  • Includes dandelion
  • Most active amounts are listed

Cons

  • No silymarin percentage
  • BioAccelerators blend is undefined
  • Three-tablet serving
  • Weak value for focused milk thistle use

Warnings

  • Dandelion and milk thistle may trigger reactions in people sensitive to ragweed-family plants
  • The undefined BioAccelerators blend limits allergy and interaction screening
  • Choline bitartrate can cause digestive discomfort in sensitive users

Nutrient quality

74 High impact

Substantial milk-thistle extract and choline amounts fit liver support well. Missing silymarin standardization and an undefined absorption blend limit quality confidence.

Ingredient transparency

55 Moderate impact

Most main ingredients have specific amounts. An undefined BioAccelerators blend, missing silymarin yield, incomplete directions, and absent tablet excipients limit transparency.

Customer satisfaction

68 High impact

The supplied satisfaction metric is strong and response volume is substantial. Specific firsthand feedback was not supplied, so recurring complaints and purpose alignment remain uncertain.

Value for money

61 Moderate impact

Substantial core ingredients and a reasonable serving cost provide fair value. Missing milk-thistle potency and the hidden absorption blend keep it only moderately competitive.

Report analysis

Goals

Detoxification
Detoxification
Impact
High effect
B+ Goal FitD Strength of SupportC+ CoverageC+ Formula Quality
Milk Thistle · 552 mgCholine · 240 mg

Milk thistle provides liver-cell protection, while choline supports healthy liver fat handling and dandelion may support bile flow. The 552 mg extract weight is substantial, but no silymarin percentage or active amount is disclosed.

Alfalfa and inositol broaden the blend without adding a clearly strong detox pathway, and the undefined BioAccelerators blend does not prove better absorption. Alfalfa can contain vitamin K, which may complicate stable dosing for people using warfarin-type anticoagulants.

Study evidence
Choline Supportive 6 studies
Milk Thistle Supportive 46 studies

Ingredients

IngredientAmount per serving
Choline (Choline Bitartrate)
 240 mg
Milk Thistle seed extract (Silymarin)
 552 mg
Dandelion
324 mg
Alfalfa leaf extract
324 mg
Inositol
240 mg
Futurebiotics BioAccelerators
23 mg
Adults 18–50 Women Vegetarian
Report overview
Choline (Choline Bitartrate) · 240 mg OverallScore60
C+ Active Ingredient Quality & BioavailabilityB- Dose, Safety & Label TransparencyF Value

Choline bitartrate provides a practical systemic form for general choline and liver support, but it is not a premium brain-targeted form. The 240 mg dose is clearly disclosed and more substantial than many low-dose blends. Requiring three tablets and offering weak cost efficiency per unit of choline are the main trade-offs.

View ingredientView products
Milk Thistle (Silymarin) · 552 mg OverallScore20
D- Active Ingredient Quality & BioavailabilityF Dose, Safety & Label TransparencyF Value

The formula uses a clearly identified milk thistle seed extract, but it does not disclose a silymarin percentage or active-marker amount. A standard dry tablet and an undefined BioAccelerators blend provide little evidence of improved silymarin absorption. The above-median serving cost is difficult to justify when potency cannot be confirmed.

View ingredientView products
Loading alternative details
85 Performance

Milk Thistle

Paradise
<p>A substantial stated silymarin amount makes milk-thistle potency more assessable than in the original. The dry capsule lacks absorption support and does not provide choline, but its focused active is clearly disclosed.</p>
84 Performance

Milk Thistle

Kroeger Herb Products Co.
<p>A separate silymarin amount from milk-thistle seed provides much clearer potency than the original’s unspecified silymarin percentage. Choline and dandelion are absent, while conventional capsule delivery offers no named absorption advantage.</p>
84 Performance

Inositol & Choline

Source Naturals
<p>Substantial choline bitartrate and inositol create a clearly dosed liver-support pair without an undefined absorption blend. Milk thistle is absent, but the core systemic ingredients are easier to evaluate than the original mixture.</p>
87 Budget

Milk Thistle Extract 175 mg

Lake Avenue Nutrition
<p>A clearly stated silymarin amount makes milk-thistle potency easier to assess at a much lower serving cost. The dry capsule lacks named absorption support and does not include choline, but it avoids the original’s undefined absorption blend and alfalfa concern.</p>
84 Budget

Choline Bitartrate 650 mg

Nutricost
<p>A meaningful elemental choline yield is clearly linked to choline bitartrate in one inexpensive capsule. It improves dose clarity and cost versus the original, although it omits milk thistle and other liver-focused botanicals.</p>
84 Budget

Choline & Inositol

NOW
<p>Choline bitartrate and inositol provide meaningful systemic and liver-oriented amounts at a much lower serving cost. The simple formula avoids the original’s unclear milk-thistle standardization, but it supplies no milk thistle at all.</p>
86 Value

Milk Thistle Extract 175 mg

Lake Avenue Nutrition
<p>A meaningful stated silymarin amount offers clear milk-thistle potency with favorable serving value. The formula omits choline and lacks named absorption support, but it is simpler and easier to assess than the original blend.</p>
83 Value

Choline 500 mg

Nature's Way
<p>A substantial choline-bitartrate amount provides focused systemic and liver-oriented support at a low serving cost. It leaves out milk thistle, yet the single active is clearer and more economical than the original’s partly unspecified formula.</p>
78 Value

Milk Thistle 30:1 Extract

Jarrow Formulas
<p>A concentrated milk-thistle extract offers focused liver support at a much lower serving cost. Plant-part and silymarin-yield details are missing and choline is absent, but the lean formula provides a clearer value proposition than the original blend.</p>
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Sources

Published studies used for the product analysis and the top-ranked studies for each ingredient and goal.

  1. Adiposity May Moderate the Link Between Choline Intake and Non-alcoholic Fatty Liver Disease.
    Mazidi M; Katsiki N; Mikhailidis DP; Banach M · Journal of the American College of Nutrition · 2020
    Cross-sectional study20,643 participantsDetoxification forCholine
  2. Relationship of Choline Intake with Biomarkers of Liver Health by Genotype-A Cross-Sectional Analysis.
    Wallace TC; Cowan-Pyle AE; Klatt KC; Bailey RL · The Journal of nutrition · 2025
    Cross-sectional study1,438 participantsDetoxification forCholine
  3. Impact of Silymarin Supplements on Liver Enzyme Levels: A Systematic Review.
    Calderon Martinez E; Herrera D; Mogan S; Hameed Z; Jangda AA; Khan TJ; Mroke P; Sajid S; Shah YR; Baig I · Cureus · 2023
    Systematic review3,846 participants29 studies pooledDetoxification forMilk Thistle
  4. Are alterations needed in Silybum marianum (Silymarin) administration practices? A novel outlook and meta-analysis on randomized trials targeting liver injury.
    Shahsavari K; Ardekani SS; Ardekani MRS; Esfahani MM; Kazemizadeh H; Jamialahmadi T; Iranshahi M; Khanavi M; Hasanpour M · BMC complementary medicine and therapies · 2025
    Meta-analysis3,545 participants55 studies pooledDetoxification forMilk Thistle
  5. Choline and contribution to normal liver function of the foetus and exclusively breastfed infants: evaluation of a health claim pursuant to Article 14 of Regulation (EC) No 1924/2006.
    EFSA Panel on Nutrition, Novel Foods and Food allergens (NDA); Turck D; Bohn T; Castenmiller J; De Henauw S; Hirsch-Ernst KI; Knutsen HK; Maciuk A; Mangelsdorf I; McArdle HJ; Naska A; Pentieva K; Thies F; Tsabouri S; Vinceti M; Bresson JL; Fiolet T; Siani A · EFSA journal. European Food Safety Authority · 2024
    Guideline / consensusDetoxification forCholine
  6. Choline and Choline-Related Metabolites in Pediatric Short Bowel Syndrome.
    Hilberath J; Shunova A; Heister L; Poets CF; Bernhard W · Nutrients · 2026
    Observational study80 participantsDetoxification forCholine
  7. Choline Supplementation in Cystic Fibrosis-The Metabolic and Clinical Impact.
    Bernhard W; Lange R; Graepler-Mainka U; Engel C; Machann J; Hund V; Shunova A; Hector A; Riethmüller J · Nutrients · 2019
    Single-arm trial10 participantsDetoxification forCholine
  8. 1H MR Spectroscopy at 3T for Hepatic Choline Quantification in Healthy Young Women: A Translational Imaging Study with Dietary Correlation.
    Hawesa H; Alghamdi R; Allam H; Alfaifi B; Alrabiah N; Alghumaiz M; Shanawani M; Alshegri H; Hassan MG · Current medical imaging · 2026
    Cohort study88 participantsDetoxification forCholine
  9. The effect of silymarin on liver enzymes in patients taking isotretinoin: A randomized clinical trial.
    Mirnezami M; Jafarimanesh H; Rezagholizamenjany M; Alimoradian A; Ranjbaran M · Dermatologic therapy · 2021
    Randomized trial74 participantsDetoxification forMilk Thistle
  10. A randomized double-blind, placebo-controlled study of therapeutic effects of silymarin in β-thalassemia major patients receiving desferrioxamine.
    Moayedi B; Gharagozloo M; Esmaeil N; Maracy MR; Hoorfar H; Jalaeikar M · European journal of haematology · 2013
    Randomized trial97 participantsDetoxification forMilk Thistle
  11. Effect of aerobic training with silymarin consumption on glycemic indices and liver enzymes in men with type 2 diabetes.
    Ghalandari K; Shabani M; Khajehlandi A; Mohammadi A · Archives of physiology and biochemistry · 2023
    Randomized trial60 participantsDetoxification forMilk Thistle
  12. Impact of silymarin-supplemented cookies on liver enzyme and inflammatory markers in non-alcoholic fatty liver disease patients.
    Jaffar HM; Bader Ul Ain H; Tufail T; Hanif A; Malik T · Food science & nutrition · 2024
    Clinical trial64 participantsDetoxification forMilk Thistle