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B12 Energizer Natural Cherry Flavor

Advanced Nutrition by Zahler
4.7
★ ★ ★ ★ ★
(1111 ratings)
Vitamin B12 1000 mcg
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Score84
A useful methylcobalamin product with substantial added folic acid. It fits combined B12-folate needs but may create unnecessary folate overlap.
How scoring works
Quantity:90 Liquid(s) • (90 servings)
Goals:
Energy
General Health
Hair Health
Productivity Boost

Score 84

A useful methylcobalamin product with substantial added folic acid. It fits combined B12-folate needs but may create unnecessary folate overlap.
How scoring works

Also available as

1 option
5000.00mcg • 120 servings 5000.00mcg • 120 Liquid(s) • 120 servings $32.47 ($0.27 per serving)
$14.27($0.15 per serving)
Pure Formulas
$ 14.27
iHerb
$ 0.00
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Analysis

The 1,000 mcg methylcobalamin amount gives substantial active-form B12 support. Folic acid complements normal blood cell formation but is present at a relatively high amount.

The pairing is coherent for users who need both nutrients. People already receiving ample folate may prefer B12 alone to avoid unnecessary overlap.

The flavored oral format can be convenient for users who dislike capsules. Full flavoring and non-active ingredients are not supplied, limiting sensitivity review.

Who is it for
  • Adults who need both B12 and folate
  • People who prefer flavored oral delivery
  • Users seeking methylcobalamin
Best for
  • Combined B12 and folate intake
  • Normal blood-cell support
  • Targeted B-vitamin supplementation

Pros

  • Uses methylcobalamin
  • Substantial B12 amount
  • Folic acid adds coherent pathway support
  • Good serving count

Cons

  • Folic acid amount may be unnecessary
  • Not suitable for users seeking B12 alone
  • Flavoring details are unavailable
  • Narrow B-vitamin focus

Warnings

  • Add the folic acid amount to intake from multivitamins and fortified foods
  • People who specifically prefer methylfolate should note that this uses folic acid
  • Missing cherry flavor ingredients limit sensitivity screening

Nutrient quality

93 Highest impact

A preferred B12 form and related cofactors create a broadly coherent formula. The amount is meaningful, though supporting additions reduce the focus of a simple B12 supplement.

.

Ingredient transparency

84 Highest impact

Active names and amounts are clearly stated, with no hidden proprietary dose. Complete intake directions and a full inactive-ingredient list are not included in the supplied data.

.

Customer satisfaction

71 High impact

Supplied satisfaction metrics indicate a strong result with a meaningful response pool. Detailed experience themes are absent, so recurring complaints and real-world purpose fit remain uncertain.

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Value for money

83 Highest impact

Serving value appears favorable relative to the disclosed form and amount. Convenience ingredients or minor additions reduce the share of value coming from the core active.

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Report analysis

Goals

Energy
Energy
Impact
Highest effect
A- Goal FitA+ Strength of SupportC+ CoverageB Formula Quality
Vitamin B12 · 1000 mcg

Methylcobalamin directly supports energy metabolism and red-blood-cell formation when vitamin B12 status is inadequate. The 1,000 mcg lozenge provides a substantial bioactive dose with clear form disclosure.

Folic acid adds related one-carbon support, but the 1,360 mcg DFE amount may be unnecessary for users already consuming fortified foods or another folate supplement. The product offers strong depth for B12-related fatigue but no alertness, mitochondrial, or adaptogen breadth.

Study evidence
Vitamin B12 Disputed 14 studies
General Health
General Health
Impact
Highest effect
A Goal FitB+ Strength of SupportC- CoverageA Formula Quality
Folate · 1360 mcg DFEVitamin B12 · 1000 mcg

Bioactive methylcobalamin and folate provide focused support for methylation and blood-cell formation. Including B12 alongside the substantial folate amount is a sensible pairing.

The folate is conventional folic acid rather than an active form, and both nutrients are highly concentrated. People already using fortified foods or another folate supplement may not need the additional folic acid load.

Study evidence
Folate Supportive 80 studies
Vitamin B12 Adverse 66 studies
Hair Health
Hair Health
Impact
High effect
C Goal FitB+ Strength of SupportC- CoverageA+ Formula Quality

Methylcobalamin and folic acid may help when deficiency contributes to diffuse shedding. They do not directly stimulate hair growth in nutritionally replete users.

The B12 form and lozenge delivery are favorable, while folic acid is less preferred than methylfolate. The substantial folate amount may be unnecessary alongside fortified foods or another folate supplement.

Study evidence
Folate Mixed 15 studies
Vitamin B12 Disputed 17 studies
Productivity Boost
Productivity Boost
Impact
High effect
C- Goal FitA Strength of SupportD CoverageB Formula Quality
Vitamin B12 · 1000 mcgVitamin B12 · 1000 mcg

Methylcobalamin may help energy and concentration when low vitamin B12 status contributes to fatigue. Folic acid supports related blood-cell pathways but does not create an acute nootropic effect.

Both nutrients are fully disclosed in substantial amounts. Benefits for productivity are likely limited when B12 and folate status are already adequate.

Study evidence
Vitamin B12 Supportive 15 studies
Vitamin B12 No effect 17 studies

Ingredients

IngredientAmount per serving
Folic Acid
1360 mcg DFE
Vitamin B12 (Methylcobalamin)
 1000 mcg
Gluten Free Adults 18–50 Kosher Dairy Free Vegetarian
Report overview
Vitamin B12 (Methylcobalamin) · 1000 mcg OverallScore96
A+ Active Ingredient Quality & BioavailabilityA+ Dose, Safety & Label TransparencyB+ Value

A bioactive methylcobalamin lozenge and a high-potency dose support strong B12 delivery. The label clearly names the form and amount, while the cost per active amount remains favorable. Added folic acid contributes a substantial folate dose that may be unnecessary for people already using fortified foods or another folate supplement.

View ingredientView products
Loading alternative details
89 Performance

Methyl B-12 1000 mcg & Methyl Folate 400 mcg plus P-5-P Lemon Flavor

Jarrow Formulas
<p>Methylcobalamin, folate, and active vitamin B6 support linked energy and methylation pathways with clearly stated amounts. The 1,000 mcg amount matches the original dose while using methylcobalamin in a focused formula.</p>
87 Performance

Fully Active B12 1500 mcg

Doctor's Best
<p>1,500 mcg of bioactive methylcobalamin provides a focused, easy-to-assess vitamin B12 option. The 1,500 mcg amount exceeds the original 1,000 mcg serving, so it fits a defined higher-intake need better than routine maintenance.</p>
87 Performance

B12 Energizer+ Natural Cherry Flavor

Advanced Nutrition by Zahler
<p>5,000 mcg of bioactive methylcobalamin provides a focused, easy-to-assess vitamin B12 option. The 5,000 mcg amount exceeds the original 1,000 mcg serving, so it fits a defined higher-intake need better than routine maintenance.</p>
86 Budget

Vitamin B12 2000 mcg

Nutricost
<p>A lower serving cost provides 2,000 mcg of methylcobalamin in a clearly disclosed formula. The 2,000 mcg amount exceeds the original 1,000 mcg serving, so it fits a defined higher-intake need better than routine maintenance.</p>
86 Budget

Quick Dissolve B-12 Methylcobalamin 2500 mcg

Nature's Bounty
<p>A lower serving cost provides 2,500 mcg of methylcobalamin in a clearly disclosed formula. The 2,500 mcg amount exceeds the original 1,000 mcg serving, so it fits a defined higher-intake need better than routine maintenance.</p>
87 Budget

B12 Methylcobalamin 1000 mcg

Natural Factors
<p>A lower serving cost provides 1,000 mcg of methylcobalamin in a clearly disclosed formula. The 1,000 mcg amount matches the original dose while using methylcobalamin in a focused formula.</p>
87 Value

Chewable Fully Active B12 Chocolate Mint Flavor 1000 mcg

Doctor's Best
<p>1,000 mcg of methylcobalamin supplies a bioactive form without low-value nutrient extras. The favorable serving cost strengthens value, and the 1,000 mcg amount matches the original dose while using methylcobalamin in a focused formula.</p>
85 Value

Vegan B12 2500 mcg

DEVA
<p>2,500 mcg of methylcobalamin supplies a bioactive form without low-value nutrient extras. The favorable serving cost strengthens value, and the 2,500 mcg amount exceeds the original 1,000 mcg serving, so it fits a defined higher-intake need better than routine maintenance.</p>
83 Value

Sublingual Methylcobalamin 1000 mcg

Solgar
<p>1,000 mcg of methylcobalamin supplies a bioactive form without low-value nutrient extras. The favorable serving cost strengthens value, and the 1,000 mcg amount matches the original dose while using methylcobalamin in a focused formula.</p>
Report alternatives

Sources

Published studies used for the product analysis and the top-ranked studies for each ingredient and goal.

  1. A new perspective on vitamin B12 deficiency in rheumatology: a case-based review.
    Dułak NA; Rytlewska M; Jaskólska M; Chmielewski M · Rheumatology international · 2024
    Case series3 participantsEnergy forVitamin B12
  2. Effects of Vitamin B12 Supplementation on Cognitive Function, Depressive Symptoms, and Fatigue: A Systematic Review, Meta-Analysis, and Meta-Regression.
    Markun S; Gravestock I; Jäger L; Rosemann T; Pichierri G; Burgstaller JM · Nutrients · 2021
    Meta-analysis6,276 participants16 studies pooledEnergy forVitamin B12
  3. Patients' experiences with methylcobalamin injections in amyotrophic lateral sclerosis.
    Zubair AS; Saab L; Scharer K; Khokhar B · Brain circulation · 2024
    Qualitative study5 participantsEnergy forVitamin B12
  4. Cobalamin deficiency: clinical picture and radiological findings.
    Briani C; Dalla Torre C; Citton V; Manara R; Pompanin S; Binotto G; Adami F · Nutrients · 2014
    Narrative reviewEnergy forVitamin B12
  5. Vitamin B12 Deficiency: Common Questions and Answers.
    Patel H; McGuirk R · American family physician · 2025
    Narrative reviewEnergy forVitamin B12
  6. Intakes of Folate, Vitamin B6, and Vitamin B12 in Relation to All-Cause and Cause-Specific Mortality: A National Population-Based Cohort.
    Bo Y; Xu H; Zhang H; Zhang J; Wan Z; Zhao X; Yu Z · Nutrients · 2022
    Cohort study55,569 participantsGeneral Health forFolate
  7. The responsiveness of plasma homocysteine to small increases in dietary folic acid: a primary care study.
    Schorah CJ; Devitt H; Lucock M; Dowell AC · European journal of clinical nutrition · 1998
    Randomized trial119 participantsGeneral Health forFolate
  8. Associations of Serum Folate and Homocysteine Concentrations with All-Cause, Cardiovascular Disease, and Cancer Mortality in Men and Women in Korea: the Cardiovascular Disease Association Study.
    Song S; Song BM; Park HY · The Journal of nutrition · 2023
    Cohort study21,260 participantsGeneral Health forFolate
  9. The concept of folic acid supplementation and its role in prevention of neural tube defect among pregnant women: PRISMA.
    Seyoum Tola F · Medicine · 2024
    Systematic reviewGeneral Health forFolate
  10. Systematic review of adverse health outcomes associated with high serum or red blood cell folate concentrations.
    Colapinto CK; O'Connor DL; Sampson M; Williams B; Tremblay MS · Journal of public health (Oxford, England) · 2017
    Systematic review71,847 participants46 studies pooledGeneral Health forFolate
  11. Oral Vitamin B12 versus Placebo for the Prevention of Chemotherapy-Induced Peripheral Neuropathy in Gynecological Cancer Patients: A Randomized, Double-Blind, Placebo-Controlled Trial.
    Insin P; Chaiwongsa T; Prueksaritanond N · Asian Pacific journal of cancer prevention : APJCP · 2026
    Randomized trial40 participantsGeneral Health forVitamin B12
  12. Vitamin B12 Supplementation in Diabetic Neuropathy: A 1-Year, Randomized, Double-Blind, Placebo-Controlled Trial.
    Didangelos T; Karlafti E; Kotzakioulafi E; Margariti E; Giannoulaki P; Batanis G; Tesfaye S; Kantartzis K · Nutrients · 2021
    Randomized trial90 participantsGeneral Health forVitamin B12
  13. A single-center randomized controlled trial of local methylcobalamin injection for subacute herpetic neuralgia.
    Xu G; Lv ZW; Feng Y; Tang WZ; Xu GX · Pain medicine (Malden, Mass.) · 2014
    Randomized trial98 participantsGeneral Health forVitamin B12
  14. Local Injection of Methylcobalamin Combined with Lidocaine for Acute Herpetic Neuralgia.
    Xǔ G; Xu S; Tang WZ; Xú G; Cheng C; Xu J · Pain medicine (Malden, Mass.) · 2017
    Randomized trial204 participantsGeneral Health forVitamin B12
  15. The Effect of Vitamin B12 and Folic Acid Supplementation on Serum Homocysteine, Anemia Status and Quality of Life of Patients with Multiple Sclerosis.
    Nozari E; Ghavamzadeh S; Razazian N · Clinical nutrition research · 2022
    Clinical trial50 participantsGeneral Health forVitamin B12
  16. Hair Loss After Metabolic and Bariatric Surgery: a Systematic Review and Meta-analysis.
    Zhang W; Fan M; Wang C; Mahawar K; Parmar C; Chen W; Yang W; Global Bariatric Research Collaborative · Obesity surgery · 2021
    Meta-analysis2,538 participants18 studies pooledHair Health forFolate
  17. Quantitative Analysis of Selected Circulating Hematological Biomarkers, Essential Minerals, Vitamins, and Thyroid Hormones in Females Affected by Hair Loss.
    Al-Fawaeir S; Al-Odat I · Diseases (Basel, Switzerland) · 2025
    Case-control study200 participantsHair Health forFolate Hair Health forVitamin B12
  18. Twelve weeks of protracted venous infusion of fluorouracil (5-FU) is as effective as 6 months of bolus 5-FU and folinic acid as adjuvant treatment in colorectal cancer.
    Saini A; Norman AR; Cunningham D; Chau I; Hill M; Tait D; Hickish T; Iveson T; Lofts F; Jodrell D; Ross PJ; Oates J · British journal of cancer · 2003
    Randomized trialHair Health forFolate
  19. Role of oxaliplatin combined with 5-fluorouracil and folinic acid in the first- and second-line treatment of advanced colorectal cancer.
    Jonker D; Rumble RB; Maroun J; Gastrointestinal Cancer Disease Site Groupof Cancer Care Ontario’s Program in Evidence-Based Care · Current oncology (Toronto, Ont.) · 2012
    Randomized trialHair Health forFolate
  20. Phase I-II study of vinorelbine in combination with 5-fluorouracil and folinic acid as first-line chemotherapy in metastatic breast cancer: a regimen with a low subjective toxic burden.
    Nolè F; de Braud F; Aapro M; Minchella I; De Pas TM; Zampino MG; Monti S; Andreoni G; Goldhirsch A · Annals of oncology : official journal of the European Society for Medical Oncology · 1997
    Randomized trialHair Health forFolate
  21. Factors Associated with Premature Hair Graying in a Young Indian Population.
    Chakrabarty S; Krishnappa PG; Gowda DG; Hiremath J · International journal of trichology · 2016
    Case-control study74 participantsHair Health forVitamin B12
  22. Risk Factors for Pediatric Alopecia Areata: Clinical and Biochemical Findings from a Case - Control Study.
    İritaş SY · Dermatology practical & conceptual · 2026
    Case-control study600 participantsHair Health forVitamin B12
  23. Hair Loss After Laparoscopic Sleeve Gastrectomy.
    Katsogridaki G; Tzovaras G; Sioka E; Perivoliotis K; Zachari E; Magouliotis D; Tasiopoulou V; Chatedaki C; Zacharoulis D · Obesity surgery · 2019
    Cohort study50 participantsHair Health forVitamin B12
  24. Demographic Characteristics and Association of Serum Vitamin B12, Ferritin and Thyroid Function with Premature Canities in Indian Patients from an Urban Skin Clinic of North India: A Retrospective Analysis of 71 Cases.
    Sonthalia S; Priya A; Tobin DJ · Indian journal of dermatology · 2022
    Cross-sectional study71 participantsHair Health forVitamin B12
  25. Effects of Folic Acid and Vitamin B12, Alone and in Combination on Cognitive Function and Inflammatory Factors in the Elderly with Mild Cognitive Impairment: A Single-blind Experimental Design.
    Ma F; Zhou X; Li Q; Zhao J; Song A; An P; Du Y; Xu W; Huang G · Current Alzheimer research · 2020
    Randomized trial240 participantsProductivity Boost forVitamin B12
  26. Effects of Physical Activity and Micronutrients on Cognitive Performance in Children Aged 6 to 11 Years: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.
    Meli AM; Ali A; Mhd Jalil AM; Mohd Yusof H; Tan MMC · Medicina (Kaunas, Lithuania) · 2022
    Meta-analysisProductivity Boost forVitamin B12
  27. Cognitive function in an elderly population: interaction between vitamin B12 status, depression, and apolipoprotein E ε4: the Hordaland Homocysteine Study.
    Vogiatzoglou A; Smith AD; Nurk E; Drevon CA; Ueland PM; Vollset SE; Nygaard HA; Engedal K; Tell GS; Refsum H · Psychosomatic medicine · 2013
    Cross-sectional study1,935 participantsProductivity Boost forVitamin B12
  28. Cognitive profile and inflammatory markers in children and adolescents with specific learning disorder: a cross-sectional study.
    Balatacı U; Ay B · Frontiers in pediatrics · 2026
    Case-control study108 participantsProductivity Boost forVitamin B12
  29. Association between vitamin B12 levels and cognitive impairment in older adults.
    Aguilar-Navarro SG; Carbajal-Silva JC; Palacios-Hernández MGI; Gutiérrez-Gutierrez LA; Ávila-Funes JA; Mimenza-Alvarado AJ · Gaceta medica de Mexico · 2023
    Cross-sectional study241 participantsProductivity Boost forVitamin B12
  30. Effects of vitamin B12 on performance and circadian rhythm in normal subjects.
    Mayer G; Kröger M; Meier-Ewert K · Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 1997
    Randomized trial20 participantsProductivity Boost forVitamin B12
  31. Prenatal vitamin B12 status and cognitive functioning in children at 4 years of age: The ECLIPSES Study.
    Cruz-Rodríguez J; Canals-Sans J; Hernández-Martínez C; Voltas-Moreso N; Arija V · Maternal & child nutrition · 2023
    Cohort study249 participantsProductivity Boost forVitamin B12
  32. Dietary intakes and biomarker patterns of folate, vitamin B6, and vitamin B12 can be associated with cognitive impairment by hypermethylation of redox-related genes NUDT15 and TXNRD1.
    An Y; Feng L; Zhang X; Wang Y; Wang Y; Tao L; Qin Z; Xiao R · Clinical epigenetics · 2020
    Cohort study2,533 participantsProductivity Boost forVitamin B12
  33. Homocysteine, folate, and vitamins B6 and B12 blood levels in relation to cognitive performance: the Maine-Syracuse study.
    Elias MF; Robbins MA; Budge MM; Elias PK; Brennan SL; Johnston C; Nagy Z; Bates CJ · Psychosomatic medicine · 2008
    Cross-sectional study812 participantsProductivity Boost forVitamin B12