Glutathione Reduced 500 mg
Jarrow Formulas
Glutathione Reduced 500 mg
4.5
★ ★ ★ ★ ★
(20719 ratings)
Glutathione 500 mg
Score 88.0
A highly potent and well-regarded reduced glutathione supplement, offering excellent value for a higher dosage.
Quantity: 60 Veggie Cap(s)Servings size: 1 Capsule(s) (60 servings)
Selected goals:
Other goals:
Anti-Aging
Detoxification
Skin Health
Anti-Inflammatory Support
leaderboard Score 88.0
A highly potent and well-regarded reduced glutathione supplement, offering excellent value for a higher dosage.
insights Analysis
Jarrow Formulas offers a high-potency 500 mg dose of reduced glutathione in a veggie cap. This dosage is often preferred for those seeking more significant support for detoxification, anti-aging, or specific health concerns. The 'Reduced' form ensures it is the active and stable form of glutathione. With a very high number of reviews, it's clear this is a highly popular and well-regarded product. The price per serving is competitive for a 500mg dose, representing good value for its potency and quality.
- High 500mg dosage for enhanced efficacy.
- Clearly specified as 'Reduced' glutathione (active form).
- Very popular with extensive positive reviews.
- Good price per serving for its potency.
- Not specified as Setria, though 'Reduced' form is generally well-absorbed.
$28.99($0.48 per serving)
 Daily Vita | $ 28.99 | |
 iHerb | $ 36.70 | |
 Amazon | $ 69.99 |
bolt Effectiveness for goals
The effectiveness of oral glutathione supplementation for directly increasing intracellular glutathione levels is a subject of ongoing research. While some studies suggest that specific forms, like liposomal or S-acetyl-glutathione, may help raise plasma glutathione, traditional forms face challenges with absorption. The body's natural synthesis of glutathione is a primary regulator of its levels.
The effectiveness of oral glutathione can vary due to challenges with absorption and degradation in the digestive system. Some forms, like liposomal or S-acetyl glutathione, are designed to improve bioavailability. Research on the systemic impact of various oral forms is ongoing.
Traditional reduced glutathione supplements have historically faced challenges with absorption due to degradation in the digestive tract. Newer forms, such as liposomal or S-acetyl-glutathione, are specifically designed to improve bioavailability and are generally considered more effectively absorbed. Research continues to evaluate the optimal delivery methods for glutathione.
Glutathione is a primary antioxidant in the body, crucial for neutralizing free radicals and combating oxidative stress. Supplementation is hypothesized to support the body's natural antioxidant defenses. The extent of this effect can depend on the supplement form and individual physiological factors.
Some research suggests that high doses of oral glutathione might have skin-lightening effects by inhibiting melanin production, but the evidence is not conclusive and often involves specific populations. These studies often require high dosages and more robust, larger-scale research is needed to confirm efficacy for this purpose. It is not approved for this use by major health authorities.
schedule Dosage, timing & forms
Liposomal glutathione encapsulates glutathione in tiny lipid bubbles (liposomes), which are designed to protect it from degradation in the digestive tract. This delivery method aims to enhance its absorption and bioavailability compared to standard oral reduced glutathione. The liposomal structure helps transport the glutathione more efficiently into the bloodstream.
N-acetylcysteine (NAC) is a precursor that the body uses to synthesize its own glutathione. While not glutathione itself, supplementing with NAC is a common strategy to support the body's endogenous glutathione production. It provides cysteine, a crucial amino acid needed for glutathione synthesis.
Oral glutathione dosages can vary widely depending on the specific form and individual needs, often ranging from 250 mg to 1000 mg per day. It's best to follow the manufacturer's recommendations on the product label. Consulting with a healthcare professional can provide personalized guidance.
Typical oral glutathione dosages can range from 250 mg to 1000 mg per day. The specific amount may vary depending on the product formulation and individual needs. It is advisable to follow the manufacturer's recommendations.
Reduced glutathione (GSH) is the active form naturally found in the body, but it can be prone to degradation during digestion when taken orally. S-acetyl glutathione is a modified form designed for improved stability and bioavailability. The acetyl group is intended to protect it until absorption, allowing it to be cleaved off inside cells to release active glutathione.
health_and_safety Safety & interactions
Oral glutathione is generally considered safe for most adults when taken in appropriate doses. Some individuals have reported mild side effects such as abdominal cramps, bloating, or allergic reactions like rash. Inhaled glutathione might cause asthma exacerbation in sensitive individuals.
Oral glutathione supplements are generally well-tolerated by most individuals. Some people might experience mild gastrointestinal discomfort, such as abdominal cramps or bloating. Rarely, allergic reactions like rash have been reported, and inhaled forms might trigger asthma in susceptible individuals.
There is limited information on significant drug interactions with glutathione supplements. However, it is always advisable to consult a healthcare professional, especially when taking prescription medications. They can assess potential interactions based on your specific health profile.
The maximum safe dosage for glutathione can vary depending on the form, individual health, and specific application. While studies have used oral doses up to 1000 mg/day, it is crucial to follow product label instructions and consult a healthcare provider for personalized guidance. Excessive doses may not provide additional benefits and could lead to unknown effects.
Insufficient research is available regarding the safety of glutathione supplementation during pregnancy and breastfeeding. For this reason, it is generally recommended to avoid use or consult a healthcare provider before considering supplementation. A healthcare professional can weigh the potential benefits against any unknown risks.
Ingredients
| Ingredient | Amount per serving |
|---|---|
Glutathione | 500 mg |
Categories
Glutathione 90.0
As a high-dose, cost-effective, and well-regarded pure glutathione product, it stands out as a top-tier option within the glutathione supplement category, meeting the needs of those seeking higher potency.
Goals
Anti-Aging 88.0
The robust 500mg dose provides strong antioxidant support against oxidative stress, a key factor in anti-aging processes, making it highly effective for cellular protection and longevity.
Detoxification 88.0
A 500mg dose is highly effective for supporting the liver's detoxification pathways and aiding in the elimination of toxins, offering significant support for the body's cleansing mechanisms.
Skin Health 88.0
Higher doses of glutathione are often sought for more pronounced effects on skin health and protection from oxidative damage, making this product well-suited for comprehensive skin support.
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