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Home›Supplements›Amino-acid›Glutamine›GI Natural Total Digestive Wellness NaturesPlus
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GI Natural Total Digestive Wellness

NaturesPlus
4.7
★ ★ ★ ★ ★
(432 ratings)
Glutamine 4000 mg
Vitamin E 100 IU
Ginger
Turmeric 50 mg
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Score84

A high-dose L-glutamine powder with probiotics and enzymes for total digestive and immune support.

How scoring works
scaleQuantity:0 lb(s) • ( servings)
track_changesGoals:
health_and_safety Immunity
local_hospital Anti-Inflammatory Support
science Detoxification
monitor_heart Cardiovascular Support

leaderboard Score 84

A high-dose L-glutamine powder with probiotics and enzymes for total digestive and immune support.

How scoring works
$29.54($0.00 per serving)
Vitacost
$ 29.54
Pure Formulas
$ 29.54
iHerb
$ 29.54
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psychologyAnalysis

This formula is built around a heavy-duty 4,000mg dose of L-glutamine, which is the primary fuel source for the cells in your digestive tract and supports the gut-immune barrier. It also includes enzymes and probiotics to assist with daily digestion and nutrient absorption.

The addition of natural Vitamin E and minerals like selenium provide antioxidant support for the gut environment. It is a very comprehensive approach for anyone looking to support their digestive resilience and overall metabolic detoxification.

thumb_upPros
  • Exceptional 4,000mg glutamine dose
  • Includes probiotics and digestive enzymes
  • Provides natural Vitamin E for gut health
  • Includes serrapeptase for structural support
thumb_downCons
  • Powder format may be inconvenient for some
  • Very low turmeric and ginger doses
  • Higher price point due to specialized ingredients
warningWarnings
  • Glutamine may affect individuals with sensitive glutamate pathways
  • Start with a smaller dose to assess digestive tolerance
scienceNutrient quality
84 Highest impact

Meaningful quantities of L-glutamine and bioavailable selenium provide solid support for intestinal barrier integrity. Some botanical and enzyme components appear underdosed, potentially limiting the overall functional impact of those specific inclusions.

scienceIngredient transparency
79 High impact

While the primary vitamins and amino acids are clearly labeled with specific dosages, several proprietary blends obscure the exact composition of enzymes and probiotics. Such a lack of transparency makes it difficult to assess the specific potency of the live cultures and digestive enzymes.

thumb_upCustomer satisfaction
92 Highest impact

Consistently high ratings across hundreds of reviews suggest a reliable experience for those seeking digestive support. Feedback aligns well with the intended purpose, with very few reports of consistent side effects or quality issues.

workspace_premiumValue for money
83 Highest impact

Including a robust 4,000mg dose of L-glutamine provides significant value relative to the purchase price in the digestive health category. Proprietary blends add less objective value, but the core nutritional profile remains competitive for the price point.

flagReport analysis
track_changesGoals
Immunity
health_and_safetyImmunity
Impact
Highest effect
B+ Goal FitA- Strength of SupportB+ CoverageA Formula Quality
Zinc · 5 mgVitamin C · 200 mgSelenium · 35 mcg

Supplying 4000mg of L-Glutamine provides substantial fuel for immune cells and supports the maintenance of intestinal barrier integrity. The gut-immune axis is a critical component of systemic defense, making this a highly relevant active.

Maintenance levels of Vitamin C, Vitamin E, and Selenium contribute additional antioxidant support for managing oxidative stress in the gut. This formula appears well-aligned for individuals seeking to support their immune health through optimized gut function.

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Anti-Inflammatory Support
local_hospitalAnti-Inflammatory Support
Impact
High effect
B Goal FitB Strength of SupportB+ CoverageB+ Formula Quality
Vitamin C · 200 mgVitamin E · 100 IU

Glutamine and natural Vitamin E provide support for maintaining cellular integrity and managing systemic oxidative markers. Serratiopeptidase and turmeric further contribute to a diverse nutritional network for systemic health.

Broad functional coverage targets multiple mechanisms of support across the digestive and systemic environments. High amounts of glutamine ensure meaningful support for metabolic pathways, although the concentration of botanical actives is relatively low.

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Detoxification
scienceDetoxification
Impact
High effect
C+ Goal FitB+ Strength of SupportC+ CoverageB+ Formula Quality
Selenium · 35 mcgVitamin C · 200 mgZinc · 5 mgGlutamine · 4000 mgVitamin E · 100 IU

Gut barrier integrity and antioxidant cofactors in this formula appear well aligned with foundational metabolic health. These ingredients may contribute to a healthy intestinal lining and systemic cellular protection.

L-glutamine and standardized Vitamin E provide focused support for intestinal health and oxidative stress management. While primarily a digestive aid, it offers some indirect support for metabolic clearance pathways.

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Cardiovascular Support
monitor_heartCardiovascular Support
Impact
High effect
C+ Goal FitB- Strength of SupportD+ CoverageB+ Formula Quality
Vitamin C · 200 mgVitamin E · 100 IUSelenium · 35 mcg

Vitamin E at 100 IU and Vitamin C at 200mg provide supportive antioxidant protection for the cardiovascular system. These nutrients help manage oxidative stress and protect healthy lipids from damage.

While focused on digestive health, the inclusion of these antioxidants and minerals like selenium contributes foundational nutrients for heart wellness. The formula offers moderate secondary support for cardiovascular markers within a specialized health product.

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scienceIngredients
IngredientAmount per serving
Vitamin C
200 mg
Vitamin E
100 IU
Calcium
100 mg
Zinc
5 mg
Selenium
35 mcg
L-Glutamine
4000 mg
Short-Chain Fatty-Acid–Promoting Prebiotic Blend
400 mg
Serrapeptase
50 mg
organic Turmeric
50 mg
Ginger
25 mg
Proprietary Probiotic Blend
25 mg
Enzyme-Rich Whole Food Blend
25 mg
Live Enzyme Blend
25 mg
grain_off Gluten Free person Adults 18–50 free_breakfast Dairy Free eco Vegetarian
flagReport overview
GlutaminestarsOverallScore77
C Active Ingredient Quality & BioavailabilityA Dose, Safety & Label TransparencyB Value
sciencehealth_and_safety
This comprehensive digestive blend provides 4,000mg of L-glutamine along with probiotics and enzymes for total gastrointestinal support. It is designed to foster a healthy gut microbiome while reinforcing the intestinal lining. This powder format is ideal for individuals looking for a complete gut-healing solution in one serving.
scienceView ingredientinventory_2View products
Vitamin EstarsOverallScore66
D Active Ingredient Quality & BioavailabilityA- Dose, Safety & Label TransparencyB- Value
monitor_heartsciencelocal_hospitalhealth_and_safety
This digestive wellness formula includes an effective dose of natural Vitamin E to help manage oxidative stress in the gut. It is a high-quality supportive ingredient in a specialized health supplement.
scienceView ingredientinventory_2View products
GingerstarsOverallScore28
F Active Ingredient Quality & BioavailabilityC- Dose, Safety & Label TransparencyF Value
local_hospitalhealth_and_safety
This digestive powder uses a small amount of ginger as a minor component of a large wellness blend. It is not an effective source for therapeutic doses of ginger.
scienceView ingredientinventory_2View products
inventory_2Alternative products
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Detoxification
Immunity
Cardiovascular Support
Anti-Inflammatory Support