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Milk Thistle 525 mg

Natrol
4.6
★ ★ ★ ★ ★
(5602 ratings)
Ginger
Milk Thistle 525 mg
Product Image
Score72
A coherent and affordable liver-focused blend, but the key milk thistle and ginger extracts lack the standardization needed to confirm potency.
How scoring works
Quantity:60 Capsule(s) • (30 servings)
Goals:
Detoxification

Score 72

A coherent and affordable liver-focused blend, but the key milk thistle and ginger extracts lack the standardization needed to confirm potency.
How scoring works
$8.48($0.28 per serving)
Vitacost
$ 8.99
Amazon
$ 8.48
iHerb
$ 9.08
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Analysis

Milk thistle is the dominant ingredient, supported by dandelion, radish, burdock, ginger, and parsley. The botanical selection is coherent for people seeking a liver-focused blend.

The large milk thistle extract weight is less informative because silymarin content and plant part are not stated. Ginger is also a minor component without a concentration ratio or active-marker level.

Clear individual amounts and a low recurring cost are practical strengths. Potency uncertainty keeps the product from matching a well-standardized milk thistle extract.

Who is it for
  • Adults seeking a broad liver-support botanical blend
  • People who value low cost and disclosed ingredient weights
Best for
  • General liver-focused botanical use
  • Users comfortable with non-standardized extracts

Pros

  • Milk thistle is the leading ingredient
  • All botanical amounts are disclosed
  • Supporting herbs fit the formula's main theme
  • Favorable qualitative value

Cons

  • Silymarin content is not stated
  • Milk thistle plant part is unclear
  • Ginger amount is small and unstandardized
  • No absorption-enhancing milk thistle technology is identified

Warnings

  • Milk thistle may trigger reactions in people sensitive to ragweed-family plants
  • Ginger may increase bleeding tendency when combined with anticoagulant or antiplatelet medicines
  • Dandelion may increase urination and can be unsuitable with some diuretics

Nutrient quality

67 High impact

The botanical selection fits a liver-oriented blend, but extract quality is poorly characterized. Unverifiable silymarin potency and modest supporting amounts keep dose confidence moderate.

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Ingredient transparency

73 High impact

Active amounts are clearly listed and no proprietary blend hides the supplied doses. Missing daily directions, excipients, and some form or potency details keep disclosure incomplete.

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Customer satisfaction

71 High impact

A strong supplied average is supported by a very large review base. Specific review comments were not provided, so repeated complaints and purpose-specific experiences cannot be assessed.

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Value for money

79 High impact

Accessible serving value and a coherent botanical combination are practical strengths. Missing silymarin standardization makes the effective value harder to confirm.

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Report analysis

Goals

Detoxification
Impact
Moderate effect
B Goal FitF Strength of SupportD+ CoverageD+ Formula Quality
Milk Thistle · 525 mg

Milk thistle extract is directly relevant to liver antioxidant protection, but the label does not reveal its silymarin content. The large extract weight therefore cannot confirm a meaningful active dose.

Dandelion, radish, burdock, ginger, and parsley add limited or uncertain metabolic-clearance support at their listed amounts. The blend has a liver-focused theme but relies too heavily on poorly specified botanicals.

Study evidence
Milk Thistle Supportive 46 studies

Ingredients

IngredientAmount per serving
Milk Thistle extract
525 mg
Dandelion
85 mg
Black Radish
60 mg
Burdock
60 mg
Ginger Rhizome Extract
60 mg
Parsley
35 mg
Adults 18–50 Dairy Free Vegetarian
Report overview
Ginger · 60 mg OverallScore47
D- Active Ingredient Quality & BioavailabilityC- Dose, Safety & Label TransparencyD- Value

The rhizome extract is clearly measured but lacks a concentration ratio and gingerol standardization. Its amount is too low to establish a useful raw-herb equivalent without more extract detail. The low serving cost limits the financial drawback, though ginger is only a minor part of this broader botanical formula.

Milk Thistle · 525 mg OverallScore16
F Active Ingredient Quality & BioavailabilityF Dose, Safety & Label TransparencyD- Value

The formula lists milk thistle extract but does not disclose its silymarin standardization or plant part. The active dose cannot be calculated, and the dry capsule provides no absorption technology. The low serving cost offers limited value because potency remains uncertain.

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Sources

Published studies used for the product analysis and the top-ranked studies for each ingredient and goal.

  1. Are alterations needed in Silybum marianum (Silymarin) administration practices? A novel outlook and meta-analysis on randomized trials targeting liver injury.
    Shahsavari K; Ardekani SS; Ardekani MRS; Esfahani MM; Kazemizadeh H; Jamialahmadi T; Iranshahi M; Khanavi M; Hasanpour M · BMC complementary medicine and therapies · 2025
    Meta-analysis3,545 participants55 studies pooledDetoxification forMilk Thistle
  2. Impact of Silymarin Supplements on Liver Enzyme Levels: A Systematic Review.
    Calderon Martinez E; Herrera D; Mogan S; Hameed Z; Jangda AA; Khan TJ; Mroke P; Sajid S; Shah YR; Baig I · Cureus · 2023
    Systematic review3,846 participants29 studies pooledDetoxification forMilk Thistle
  3. Effect of 8 Weeks milk thistle powder (silymarin extract) supplementation on fatty liver disease in patients candidates for bariatric surgery.
    Mirhashemi SH; Hakakzadeh A; Yeganeh FE; Oshidari B; Rezaee SP · Metabolism open · 2022
    Observational studyDetoxification forMilk Thistle
  4. Evaluation of Hepatoprotective Effect of Silymarin Among Under Treatment Tuberculosis Patients: A Randomized Clinical Trial.
    Marjani M; Baghaei P; Kazempour Dizaji M; Gorji Bayani P; Fahimi F; Tabarsi P; Velayati AA · Iranian journal of pharmaceutical research : IJPR · 2016
    Randomized trial70 participantsDetoxification forMilk Thistle
  5. A randomized controlled trial to assess the safety and efficacy of silymarin on symptoms, signs and biomarkers of acute hepatitis.
    El-Kamary SS; Shardell MD; Abdel-Hamid M; Ismail S; El-Ateek M; Metwally M; Mikhail N; Hashem M; Mousa A; Aboul-Fotouh A; El-Kassas M; Esmat G; Strickland GT · Phytomedicine : international journal of phytotherapy and phytopharmacology · 2009
    Randomized trial105 participantsDetoxification forMilk Thistle
  6. A double-blinded randomized controlled trial of silymarin for the prevention of antituberculosis drug-induced liver injury.
    Luangchosiri C; Thakkinstian A; Chitphuk S; Stitchantrakul W; Petraksa S; Sobhonslidsuk A · BMC complementary and alternative medicine · 2016
    Randomized trial55 participantsDetoxification forMilk Thistle
  7. The effect of silymarin on liver enzymes in patients taking isotretinoin: A randomized clinical trial.
    Mirnezami M; Jafarimanesh H; Rezagholizamenjany M; Alimoradian A; Ranjbaran M · Dermatologic therapy · 2021
    Randomized trial74 participantsDetoxification forMilk Thistle
  8. A randomized double-blind, placebo-controlled study of therapeutic effects of silymarin in β-thalassemia major patients receiving desferrioxamine.
    Moayedi B; Gharagozloo M; Esmaeil N; Maracy MR; Hoorfar H; Jalaeikar M · European journal of haematology · 2013
    Randomized trial97 participantsDetoxification forMilk Thistle
  9. Effect of aerobic training with silymarin consumption on glycemic indices and liver enzymes in men with type 2 diabetes.
    Ghalandari K; Shabani M; Khajehlandi A; Mohammadi A · Archives of physiology and biochemistry · 2023
    Randomized trial60 participantsDetoxification forMilk Thistle
  10. Impact of silymarin-supplemented cookies on liver enzyme and inflammatory markers in non-alcoholic fatty liver disease patients.
    Jaffar HM; Bader Ul Ain H; Tufail T; Hanif A; Malik T · Food science & nutrition · 2024
    Clinical trial64 participantsDetoxification forMilk Thistle