Published studies used for the product analysis and the top-ranked studies for each ingredient and goal.
- Effect of caffeine ingestion on time trial performance in cyclists: a systematic review and meta-analysis.
Chen B; Ding L; Qin Q; Lei TH; Girard O; Cao Y · Journal of the International Society of Sports Nutrition · 2024
Meta-analysis15 studies pooledflagFitness forscienceCaffeine
- Using coffee to compensate for poor sleep: Impact on vigilance and implications for workplace performance.
Anderson JR; Hagerdorn PL; Gunstad J; Spitznagel MB · Applied ergonomics · 2018
Randomized trial69 participantsflagMental Focus forscienceCaffeine
- Caffeine administration at night during extended wakefulness effectively mitigates performance impairment but not subjective assessments of fatigue and sleepiness.
Paech GM; Banks S; Pajcin M; Grant C; Johnson K; Kamimori GH; Vedova CB · Pharmacology, biochemistry, and behavior · 2017
Randomized trial24 participantsflagEnergy forscienceCaffeine
- High-power therapeutic ultrasound for treatment of abdominal localized adiposity-double-blind randomized clinical trial.
da Silva Siqueira K; Maia JM · Lasers in medical science · 2020
Randomized trial90 participantsflagWeight Loss forscienceCaffeine
- No effects of caffeine on cycling to exhaustion and perceptual responses in non-caffeine-restricted subjects.
Weippert M; Behrens M; Schlegel M; Schröder T; Tillmann M; Rühe N; Römer R; Mau-Möller A; Bruhn S · Journal of the International Society of Sports Nutrition · 2025
Randomized trial56 participantsflagEnergy flagFitness forscienceCaffeine
- Physiological and cognitive responses to caffeine during repeated, high-intensity exercise.
Crowe MJ; Leicht AS; Spinks WL · International journal of sport nutrition and exercise metabolism · 2007
Randomized trial17 participantsflagMental Focus forscienceCaffeine
- Maternal, but not paternal or grandparental, caffeine intake is associated with childhood obesity and adiposity: The Lifeways Cross-Generation Cohort Study.
Chen LW; Murrin CM; Mehegan J; Kelleher CC; Phillips CM; Cross-Generation Cohort Study for the Lifeways · The American journal of clinical nutrition · 2020
Cohort study558 participantsflagWeight Loss forscienceCaffeine
- A critical review of caffeine withdrawal: empirical validation of symptoms and signs, incidence, severity, and associated features.
Juliano LM; Griffiths RR · Psychopharmacology · 2005
Systematic review66 studies pooledflagEnergy forscienceCaffeine
- Caffeinated Coffee and Tea Consumption, Genetic Variation and Cognitive Function in the UK Biobank.
Cornelis MC; Weintraub S; Morris MC · The Journal of nutrition · 2020
Cross-sectional study445,786 participantsflagMental Focus forscienceCaffeine
- Safety and efficacy of long-term treatment with ephedrine, caffeine and an ephedrine/caffeine mixture.
Toubro S; Astrup AV; Breum L; Quaade F · International journal of obesity and related metabolic disorders : journal of the International Association for the Study of Obesity · 1993
Randomized trial180 participantsflagWeight Loss forscienceCaffeine
- Effect of caffeine ingestion on cycling performance: a systematic review and meta-analysis.
Wu J; Xu K; Yin M; Ding X; Wang T; Zhang Q; Wu X; Xiao N · Frontiers in nutrition · 2026
Meta-analysis226 participants20 studies pooledflagFitness forscienceCaffeine
- Effects of Caffeine Intake on Endurance Running Performance and Time to Exhaustion: A Systematic Review and Meta-Analysis.
Wang Z; Qiu B; Gao J; Del Coso J · Nutrients · 2023
Meta-analysis254 participants21 studies pooledflagFitness forscienceCaffeine
- Acute effects of caffeine on attention: a comparison of non-consumers and withdrawn consumers.
Smith AP; Christopher G; Sutherland D · Journal of psychopharmacology (Oxford, England) · 2013
Randomized trial70 participantsflagMental Focus forscienceCaffeine
- Differential cognitive effects of energy drink ingredients: caffeine, taurine, and glucose.
Giles GE; Mahoney CR; Brunyé TT; Gardony AL; Taylor HA; Kanarek RB · Pharmacology, biochemistry, and behavior · 2013
Randomized trial48 participantsflagEnergy forscienceCaffeine
- Does caffeine ingestion before a short-term sprint interval training promote body fat loss?
Ferreira GA; Felippe LC; Bertuzzi R; Bishop DJ; Ramos IS; De-Oliveira FR; Lima-Silva AE · Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas · 2020
Randomized trial20 participantsflagWeight Loss forscienceCaffeine
- Caffeine, CYP1A2 Genotype, and Endurance Performance in Athletes.
Guest N; Corey P; Vescovi J; El-Sohemy A · Medicine and science in sports and exercise · 2019
Randomized trial101 participantsflagFitness forscienceCaffeine
- Effects of modafinil and caffeine on night-time vigilance of air force crewmembers: A randomized controlled trial.
Wingelaar-Jagt YQ; Bottenheft C; Riedel WJ; Ramaekers JG · Journal of psychopharmacology (Oxford, England) · 2023
Randomized trial32 participantsflagMental Focus forscienceCaffeine
- Does Single or Combined Caffeine and Taurine Supplementation Improve Athletic and Cognitive Performance without Affecting Fatigue Level in Elite Boxers? A Double-Blind, Placebo-Controlled Study.
Ozan M; Buzdagli Y; Eyipinar CD; Baygutalp NK; Yüce N; Oget F; Kan E; Baygutalp F · Nutrients · 2022
Randomized trial20 participantsflagEnergy forscienceCaffeine
- Eight Weeks of Sprint Interval Training With Adding Caffeine Ingestion Leads to Greater Improvements in Health-Related Physiological Parameters in Obese Male Adults.
Zhiang J; Song Q · Physiological research · 2026
Randomized trial30 participantsflagWeight Loss forscienceCaffeine
- Placebo in sports nutrition: a proof-of-principle study involving caffeine supplementation.
Saunders B; de Oliveira LF; da Silva RP; de Salles Painelli V; Gonçalves LS; Yamaguchi G; Mutti T; Maciel E; Roschel H; Artioli GG; Gualano B · Scandinavian journal of medicine & science in sports · 2018
Randomized trial42 participantsflagFitness forscienceCaffeine
- The effects of L-theanine, caffeine and their combination on cognition and mood.
Haskell CF; Kennedy DO; Milne AL; Wesnes KA; Scholey AB · Biological psychology · 2008
Randomized trialflagMental Focus forscienceCaffeine
- Trait Energy and Fatigue Modify the Effects of Caffeine on Mood, Cognitive and Fine-Motor Task Performance: A Post-Hoc Study.
Fuller DT; Smith ML; Boolani A · Nutrients · 2021
Randomized trialflagEnergy forscienceCaffeine
- An Examination of a Novel Weight Loss Supplement on Anthropometry and Indices of Cardiovascular Disease Risk.
Sowinski RJ; Grubic TJ; Dalton RL; Schlaffer J; Reyes-Elrod AG; Jenkins VM; Williamson S; Rasmussen C; Murano PS; Earnest CP; Kreider RB · Journal of dietary supplements · 2021
Randomized trial68 participantsflagWeight Loss forscienceCaffeine
- Acute Effects of Caffeine Supplementation on Movement Velocity in Resistance Exercise: A Systematic Review and Meta-analysis.
Raya-González J; Rendo-Urteaga T; Domínguez R; Castillo D; Rodríguez-Fernández A; Grgic J · Sports medicine (Auckland, N.Z.) · 2021
Meta-analysis12 studies pooledflagFitness forscienceCaffeine
- Caffeine and attentional control: improved and impaired performance in healthy older adults and Parkinson's disease according to task demands.
Sharma K; Fallon SJ; Davis T; Ankrett S; Munro G; Christopher G; Coulthard E · Psychopharmacology · 2022
Randomized trial68 participantsflagMental Focus forscienceCaffeine
- Effect of Caffeine on Golf Performance and Fatigue during a Competitive Tournament.
Mumford PW; Tribby AC; Poole CN; Dalbo VJ; Scanlan AT; Moon JR; Roberts MD; Young KC · Medicine and science in sports and exercise · 2016
Randomized trial12 participantsflagEnergy forscienceCaffeine
- Maternal caffeine intake during pregnancy, early growth, and body fat distribution at school age.
Voerman E; Jaddoe VW; Gishti O; Hofman A; Franco OH; Gaillard R · Obesity (Silver Spring, Md.) · 2017
Cohort study7,857 participantsflagWeight Loss forscienceCaffeine
- Acute Effects of Caffeine Supplementation on Physical Performance, Physiological Responses, Perceived Exertion, and Technical-Tactical Skills in Combat Sports: A Systematic Review and Meta-Analysis.
Delleli S; Ouergui I; Messaoudi H; Trabelsi K; Ammar A; Glenn JM; Chtourou H · Nutrients · 2022
Meta-analysis26 studies pooledflagFitness forscienceCaffeine
- The combined effects of L-theanine and caffeine on cognitive performance and mood.
Owen GN; Parnell H; De Bruin EA; Rycroft JA · Nutritional neuroscience · 2009
Randomized trial27 participantsflagMental Focus forscienceCaffeine
- Effects of Caffeine Intake on Cognitive Performance Related to Total Sleep Deprivation and Time on Task: A Randomized Cross-Over Double-Blind Study.
Quiquempoix M; Sauvet F; Erblang M; Van Beers P; Guillard M; Drogou C; Trignol A; Vergez A; Léger D; Chennaoui M; Gomez-Merino D; Rabat A · Nature and science of sleep · 2022
Randomized trial24 participantsflagEnergy forscienceCaffeine
- Prenatal Substance Exposure and Obesity: Trajectories of Tri-Ponderal Mass Index in Early Adolescence.
Li R; Wigley IM; Suuronen I; Jolly A; Tuulari JJ · American journal of preventive medicine · 2025
Cohort study7,881 participantsflagWeight Loss forscienceCaffeine
- Can I Have My Coffee and Drink It? A Systematic Review and Meta-analysis to Determine Whether Habitual Caffeine Consumption Affects the Ergogenic Effect of Caffeine.
Carvalho A; Marticorena FM; Grecco BH; Barreto G; Saunders B · Sports medicine (Auckland, N.Z.) · 2022
Meta-analysis60 studies pooledflagFitness forscienceCaffeine
- The effect of mouth rinsing with different concentrations of caffeine solutions on reaction time.
Virdinli SG; Kutlay E; Yuzbasioglu Y; Vollaard NBJ; Rudarli Nalcakan G · Journal of sports sciences · 2022
Randomized trial45 participantsflagMental Focus forscienceCaffeine
- Caffeine Supplementation and Physical Performance, Muscle Damage and Perception of Fatigue in Soccer Players: A Systematic Review.
Mielgo-Ayuso J; Calleja-Gonzalez J; Del Coso J; Urdampilleta A; León-Guereño P; Fernández-Lázaro D · Nutrients · 2019
Systematic review17 participants17 studies pooledflagEnergy forscienceCaffeine
- Caffeine treatment prevented from weight regain after calorie shifting diet induced weight loss.
Davoodi SH; Hajimiresmaiel SJ; Ajami M; Mohseni-Bandpei A; Ayatollahi SA; Dowlatshahi K; Javedan G; Pazoki-Toroudi H · Iranian journal of pharmaceutical research : IJPR · 2014
Non-randomized trial60 participantsflagWeight Loss forscienceCaffeine
- Sex Differences in the Ergogenic Response of Acute Caffeine Intake on Muscular Strength, Power and Endurance Performance in Resistance-Trained Individuals: A Randomized Controlled Trial.
Montalvo-Alonso JJ; Ferragut C; Del Val-Manzano M; Valadés D; Roberts J; Pérez-López A · Nutrients · 2024
Randomized trial76 participantsflagFitness forscienceCaffeine
- Caffeine attenuates scopolamine-induced memory impairment in humans.
Riedel W; Hogervorst E; Leboux R; Verhey F; van Praag H; Jolles J · Psychopharmacology · 1996
Randomized trial16 participantsflagMental Focus forscienceCaffeine
- Effect of caffeine intake on fat oxidation rate during exercise: is there a dose-response effect?
Gutiérrez-Hellín J; Aguilar-Navarro M; Ruiz-Moreno C; Muñoz A; Varillas-Delgado D; Amaro-Gahete FJ; Del Coso J · European journal of nutrition · 2023
Randomized trial18 participantsflagEnergy flagMetabolism Boost forscienceCaffeine
- Interventions associated with brown adipose tissue activation and the impact on energy expenditure and weight loss: A systematic review.
Perez LC; Perez LT; Nene Y; Umpierrez GE; Davis GM; Pasquel FJ · Frontiers in endocrinology · 2022
Systematic review47 studies pooledflagWeight Loss forscienceCaffeine
- Cognitive and mood improvements of caffeine in habitual consumers and habitual non-consumers of caffeine.
Haskell CF; Kennedy DO; Wesnes KA; Scholey AB · Psychopharmacology · 2005
Randomized trial48 participantsflagEnergy forscienceCaffeine
- Caffeine-containing energy drink improves physical performance of elite rugby players during a simulated match.
Del Coso J; Ramírez JA; Muñoz G; Portillo J; Gonzalez-Millán C; Muñoz V; Barbero-Álvarez JC; Muñoz-Guerra J · Applied physiology, nutrition, and metabolism = Physiologie appliquee, nutrition et metabolisme · 2016
Randomized trial26 participantsflagEnergy forscienceCaffeine
- Magnesium-L-threonate improves sleep quality and daytime functioning in adults with self-reported sleep problems: A randomized controlled trial.
Hausenblas HA; Lynch T; Hooper S; Shrestha A; Rosendale D; Gu J · Sleep medicine: X · 2025
Randomized trial80 participantsflagEnergy forscienceMagnesium
- Total magnesium intake and risk of frailty in older women.
Struijk EA; Fung TT; Bischoff-Ferrari HA; Willett WC; Lopez-Garcia E · Journal of cachexia, sarcopenia and muscle · 2024
Cohort study81,524 participantsflagEnergy forscienceMagnesium
- Red blood cell magnesium and chronic fatigue syndrome.
Cox IM; Campbell MJ; Dowson D · Lancet (London, England) · 1991
Randomized trial32 participantsflagEnergy forscienceMagnesium
- Exercise, magnesium and immune function.
Laires MJ; Monteiro C · Magnesium research · 2008
Narrative reviewflagEnergy forscienceMagnesium
- [Efficacy of potassium N-acetylaminosuccinate (Cogitum) in the treatment of asthenic syndrome: results of double-blind placebo-controlled trial].
Esin RG; Khayrullin IK; Esin OR; Fatykhova AF; Gismatullina EI; Isaeva YN · Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova · 2023
Randomized trial37 participantsflagEnergy forsciencePotassium
- Human resting energy expenditure in relation to dietary potassium.
Dériaz O; Thériault G; Lavallée N; Fournier G; Nadeau A; Bouchard C · The American journal of clinical nutrition · 1991
Randomized trial8 participantsflagEnergy forsciencePotassium
- Additive effects of beta-alanine and sodium bicarbonate on upper-body intermittent performance.
Tobias G; Benatti FB; de Salles Painelli V; Roschel H; Gualano B; Sale C; Harris RC; Lancha AH; Artioli GG · Amino acids · 2013
Randomized trial37 participantsflagFitness forscienceSodium
- Sodium Hyperhydration Improves Performance With No Change in Thermal and Cardiovascular Strain in Female Cyclists Exercising in the Heat Across the Menstrual Cycle.
Convit L; Orellana L; Périard JD; Carr AJ; Warmington S; Beaugeois M; Abraham A; Snipe RMJ · International journal of sport nutrition and exercise metabolism · 2025
Randomized trial12 participantsflagFitness forscienceSodium
- Sodium bicarbonate supplementation improves severe-intensity intermittent exercise under moderate acute hypoxic conditions.
Deb SK; Gough LA; Sparks SA; McNaughton LR · European journal of applied physiology · 2018
Randomized trial11 participantsflagFitness forscienceSodium
- International Society of Sports Nutrition position stand: sodium bicarbonate and exercise performance.
Grgic J; Pedisic Z; Saunders B; Artioli GG; Schoenfeld BJ; McKenna MJ; Bishop DJ; Kreider RB; Stout JR; Kalman DS; Arent SM; VanDusseldorp TA; Lopez HL; Ziegenfuss TN; Burke LM; Antonio J; Campbell BI · Journal of the International Society of Sports Nutrition · 2021
Guideline / consensusflagFitness forscienceSodium
- The effects of sodium bicarbonate ingestion on swimming interval performance in trained competitive swimmers.
Gough LA; Newbury JW; Price M · European journal of applied physiology · 2023
Randomized trial14 participantsflagFitness forscienceSodium
- Performance and alertness effects of caffeine, dextroamphetamine, and modafinil during sleep deprivation.
Wesensten NJ; Killgore WD; Balkin TJ · Journal of sleep research · 2006
Randomized trial48 participantsflagMental Focus forscienceCaffeine
- Effects of caffeine on mood and performance: a study of realistic consumption.
Brice CF; Smith AP · Psychopharmacology · 2003
Clinical trial24 participantsflagMental Focus forscienceCaffeine
- Effects of caffeine or diphenhydramine on visual vigilance.
Fine BJ; Kobrick JL; Lieberman HR; Marlowe B; Riley RH; Tharion WJ · Psychopharmacology · 1995
Randomized trial24 participantsflagMental Focus forscienceCaffeine
- A Randomized Study to Examine the Ability of a Caffeine-Based Energy Drink to Impact Energy Expenditure, Fat Oxidation, and Cognitive Performance.
Krieger J; Schrautemeier A; Hagele A; Gaige C; Mennemeyer O; Tolbert S; Iannotti J; Kerksick C; Noonan C; Mumford P · Nutrients · 2025
Randomized trial60 participantsflagMetabolism Boost forscienceCaffeine
- Oolong tea increases metabolic rate and fat oxidation in men.
Rumpler W; Seale J; Clevidence B; Judd J; Wiley E; Yamamoto S; Komatsu T; Sawaki T; Ishikura Y; Hosoda K · The Journal of nutrition · 2001
Randomized trial12 participantsflagMetabolism Boost forscienceCaffeine
- Comparison of changes in energy expenditure and body temperatures after caffeine consumption.
Koot P; Deurenberg P · Annals of nutrition & metabolism · 1995
Randomized trial12 participantsflagMetabolism Boost forscienceCaffeine
- Caffeine Increases Work Done above Critical Power, but Not Anaerobic Work.
Silveira R; Andrade-Souza VA; Arcoverde L; Tomazini F; Sansonio A; Bishop DJ; Bertuzzi R; Lima-Silva AE · Medicine and science in sports and exercise · 2018
Randomized trial9 participantsflagMetabolism Boost forscienceCaffeine
- Effects of caffeine on alertness.
Zwyghuizen-Doorenbos A; Roehrs TA; Lipschutz L; Timms V; Roth T · Psychopharmacology · 1990
Randomized trial24 participantsflagProductivity Boost forscienceCaffeine
- Effects of Different Sources of Low-Dose Caffeine on Mood/Arousal and Cognitive Performance.
Irwin C; McCartney D; Grant G; Delang N; Bartrim K; Cox GR; Desbrow B · Perceptual and motor skills · 2023
Randomized trial22 participantsflagProductivity Boost forscienceCaffeine
- Effects of caffeine, sleep loss, and stress on cognitive performance and mood during U.S. Navy SEAL training. Sea-Air-Land.
Lieberman HR; Tharion WJ; Shukitt-Hale B; Speckman KL; Tulley R · Psychopharmacology · 2003
Randomized trial68 participantsflagProductivity Boost forscienceCaffeine
- A review of caffeine's effects on cognitive, physical and occupational performance.
McLellan TM; Caldwell JA; Lieberman HR · Neuroscience and biobehavioral reviews · 2017
Narrative reviewflagProductivity Boost forscienceCaffeine
- Acute caffeine supplementation as a nutrition-based strategy to mitigate sleep-loss-related cognitive and operational performance impairments in military personnel: a systematic review and meta-analysis.
Wang R; Wang W; Meng L; Hao G; Gu G · Frontiers in nutrition · 2026
Meta-analysis7 studies pooledflagProductivity Boost forscienceCaffeine
- Changes in caffeine intake and long-term weight change in men and women.
Lopez-Garcia E; van Dam RM; Rajpathak S; Willett WC; Manson JE; Hu FB · The American journal of clinical nutrition · 2006
Cohort study58,157 participantsflagWeight Loss forscienceCaffeine
- The effects of caffeine intake on weight loss: a systematic review and dos-response meta-analysis of randomized controlled trials.
Tabrizi R; Saneei P; Lankarani KB; Akbari M; Kolahdooz F; Esmaillzadeh A; Nadi-Ravandi S; Mazoochi M; Asemi Z · Critical reviews in food science and nutrition · 2020
Meta-analysis606 participants13 studies pooledflagWeight Loss forscienceCaffeine