Gold Standard Pre Advanced Berry Blast

Gold Standard Pre Advanced Berry Blast

Optimum Nutrition4.8 (25 ratings)
Format:Powder Quantity: 14 Ounce(s) · 20 servings
Goals
$39.99 $1.99 per serving

About this product

Micronized citrulline, creatine monohydrate, creatine nitrate, and beta-alanine form a substantial performance base. Electrolytes and magnesium add training support, while caffeine provides a strong stimulant effect.

The key ingredients are fully disclosed and reach meaningful amounts, making the formula more complete than caffeine-led pre-workouts with token performance doses. The caffeine serving is aggressive, and the electrolyte blend does not reveal each component's amount.

Experienced stimulant users training for strength, power, or high-intensity conditioning may find the formula effective. Anyone with low caffeine tolerance, evening training, or a separate daily creatine routine may need a smaller serving or different product.

Who is it for
  • Experienced stimulant users doing demanding workouts
  • Adults seeking creatine, citrulline, and beta-alanine in one formula
Best for
  • Strength and high-intensity training
  • Workout energy and blood-flow support

Pros

  • Substantial citrulline amount
  • Full creatine monohydrate serving plus creatine nitrate
  • Meaningful beta-alanine amount
  • Includes electrolytes and magnesium

Cons

  • Very high caffeine amount
  • Electrolyte blend is not itemized
  • Premium serving cost
  • Poor fit for late-day training

Warnings

  • The high caffeine dose may cause anxiety, palpitations, or insomnia
  • Beta-alanine can cause strong temporary tingling
  • Avoid combining with coffee, energy drinks, or other pre-workouts
  • People with low stimulant tolerance should not begin with a full serving

Product analysis

68 out of 100
A well-dosed performance pre-workout with strong creatine, citrulline, and beta-alanine support, but its aggressive caffeine level sharply limits flexibility.

AI assessment of the formula, label and price. How scoring works

Nutrient quality84

Clinically familiar amounts of citrulline, creatine, and beta-alanine provide excellent performance depth. High caffeine and some creatine redundancy reduce balance.

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Ingredient transparency67

Core performance doses are clearly stated, but the electrolyte blend conceals its components. Complete directions, inactive ingredients, and caffeine source remain missing.

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Customer satisfaction58

The supplied average is very strong and based on a small sample. No review themes were provided, so consistency and purpose-specific experience cannot be assessed.

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Value for money58

Excellent core dosing provides meaningful quality value. A very high serving cost and hidden electrolyte composition weaken category competitiveness.

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Format
Powder
Container
14 Ounce(s)
Per serving
$1.99
Customer rating
4.8 · 25 ratings
Report analysis

Goals

Impact
Highest effect
B Ingredient FitA+ PathwaysA EvidenceA+ Formulation Logic
Magnesium · 100 mgVitamin D · 10 mcgCreatine · 1.2 Gram(s)Citrulline · 6 Gram(s)Beta-Alanine · 3.2 Gram(s)Caffeine · 300 mg
Study evidence
Caffeine Supportive 255 studies
Citrulline Supportive 45 studies
Creatine Supportive 143 studies
Impact
Highest effect
B+ Ingredient FitB+ PathwaysA+ EvidenceA+ Formulation Logic
Vitamin D · 10 mcgMagnesium · 100 mgCaffeine · 300 mgCreatine · 1.2 Gram(s)
Study evidence
Caffeine Supportive 68 studies
Citrulline No effect 14 studies
Creatine Supportive 49 studies
Muscle Gain
Impact
Highest effect
B Ingredient FitB+ PathwaysA- EvidenceA Formulation Logic
Vitamin D · 10 mcgCreatine · 1.2 Gram(s)Caffeine · 300 mgCitrulline · 6 Gram(s)Beta-Alanine · 3.2 Gram(s)
Study evidence
Caffeine Supportive 31 studies
Citrulline Supportive 15 studies
Creatine Supportive 136 studies
Weight Loss
Impact
High effect
C Ingredient FitD PathwaysB+ EvidenceA+ Formulation Logic
Vitamin D · 10 mcgMagnesium · 100 mgCreatine · 1.2 Gram(s)Caffeine · 300 mg
Study evidence
Caffeine Disputed 14 studies
Creatine No effect 27 studies
Productivity Boost
Impact
High effect
C Ingredient FitB+ PathwaysA+ EvidenceA Formulation Logic
Magnesium · 100 mgCreatine · 1.2 Gram(s)Caffeine · 300 mg
Study evidence
Caffeine Supportive 108 studies
Creatine Supportive 16 studies
Metabolism Boost
Impact
High effect
C Ingredient FitB+ PathwaysA+ EvidenceA+ Formulation Logic
Vitamin D · 10 mcgMagnesium · 100 mgCreatine · 1.2 Gram(s)Caffeine · 300 mg
Study evidence
Caffeine Disputed 40 studies
Mental Focus
Impact
High effect
C Ingredient FitB+ PathwaysA+ EvidenceA Formulation Logic
Vitamin D · 10 mcgMagnesium · 100 mgCreatine · 1.2 Gram(s)Caffeine · 300 mg
Study evidence
Caffeine Supportive 128 studies
Creatine Supportive 13 studies

Ingredients

IngredientAmount per servingScore
Calories
5 Calorie(s)
Total Carbohydrates
1 Gram(s)
Vitamin C (Ascorbic Acid)
200 mg
Vitamin D (Cholecalciferol)
10 mcg
Calcium
30 mg
Magnesium
100 mg
Sodium
100 mg
L-Citrulline, Micronized
6 Gram(s)
Creatine Monohydrate
5 Gram(s)
CarnoSyn (Beta-Alanine)
3.2 Gram(s)
Creatine Nitrate
1.2 Gram(s)
Electrolyte Blend
650 mg
Caffeine
300 mg 55
Adults 18–50 Women
Report overview
Caffeine · 300 mg OverallScore55
D- Active Ingredient Quality & BioavailabilityA Dose, Safety & Label TransparencyF Value
The product states a 300 mg caffeine amount, but the saved facts show caffeine identified only under Other Ingredients, without a more specific source form. No secondary stimulants are listed. The amount is at the upper end of the range described for acute focus and performance, while the cost per serving is very high.
How this ingredient is rated

Active Ingredient Quality & Bioavailability40

Caffeine appears under Other Ingredients, with no more specific form listed.
Advanced Bioavailability and Release Profiles
The saved facts identify caffeine but leave its specific form unknown.

Dose, Safety & Label Transparency92

The label states the total amount, and no secondary stimulants are listed in the saved facts.
Caffeine Dose Transparency
The stated total is 300 mg per serving.
Dosage Efficacy and Safety Margin
At 300 mg, it is at the upper end of the described range for acute focus and performance.
Secondary Stimulant Disclosure and Risk
The saved facts list no secondary stimulants.

Value10

The cost per serving is very high.
Price Per Serving vs. Collection Median
Its per-serving cost is above the very-high-cost threshold.
Loading alternative details
Report alternatives

Sources

Published studies used for the product analysis and the top-ranked studies for each ingredient and goal.

  1. Cognitive and mood improvements of caffeine in habitual consumers and habitual non-consumers of caffeine.
    Haskell CF; Kennedy DO; Wesnes KA; Scholey AB · Psychopharmacology · 2005
    Randomized trial48 participantsEnergy forCaffeine
  2. Caffeine-containing energy drink improves physical performance of elite rugby players during a simulated match.
    Del Coso J; Ramírez JA; Muñoz G; Portillo J; Gonzalez-Millán C; Muñoz V; Barbero-Álvarez JC; Muñoz-Guerra J · Applied physiology, nutrition, and metabolism = Physiologie appliquee, nutrition et metabolisme · 2016
    Randomized trial26 participantsEnergy forCaffeine
  3. Differential cognitive effects of energy drink ingredients: caffeine, taurine, and glucose.
    Giles GE; Mahoney CR; Brunyé TT; Gardony AL; Taylor HA; Kanarek RB · Pharmacology, biochemistry, and behavior · 2013
    Randomized trial48 participantsEnergy forCaffeine
  4. Does Single or Combined Caffeine and Taurine Supplementation Improve Athletic and Cognitive Performance without Affecting Fatigue Level in Elite Boxers? A Double-Blind, Placebo-Controlled Study.
    Ozan M; Buzdagli Y; Eyipinar CD; Baygutalp NK; Yüce N; Oget F; Kan E; Baygutalp F · Nutrients · 2022
    Randomized trial20 participantsEnergy forCaffeine
  5. Trait Energy and Fatigue Modify the Effects of Caffeine on Mood, Cognitive and Fine-Motor Task Performance: A Post-Hoc Study.
    Fuller DT; Smith ML; Boolani A · Nutrients · 2021
    Randomized trialEnergy forCaffeine
  6. Acute Effect of Citrulline Malate on Repetition Performance During Strength Training: A Systematic Review and Meta-Analysis.
    Vårvik FT; Bjørnsen T; Gonzalez AM · International journal of sport nutrition and exercise metabolism · 2021
    Meta-analysis137 participants8 studies pooledEnergy forCitrulline
  7. Oral L-citrulline supplementation enhances cycling time trial performance in healthy trained men: Double-blind randomized placebo-controlled 2-way crossover study.
    Suzuki T; Morita M; Kobayashi Y; Kamimura A · Journal of the International Society of Sports Nutrition · 2016
    Randomized trial22 participantsEnergy forCitrulline
  8. Citrulline malate enhances athletic anaerobic performance and relieves muscle soreness.
    Pérez-Guisado J; Jakeman PM · Journal of strength and conditioning research · 2010
    Randomized trial41 participantsEnergy forCitrulline
  9. Citrulline/malate promotes aerobic energy production in human exercising muscle.
    Bendahan D; Mattei JP; Ghattas B; Confort-Gouny S; Le Guern ME; Cozzone PJ · British journal of sports medicine · 2002
    Single-arm trial18 participantsEnergy forCitrulline
  10. The Effect of Citrulline Malate Supplementation on Muscle Fatigue Among Healthy Participants.
    Farney TM; Bliss MV; Hearon CM; Salazar DA · Journal of strength and conditioning research · 2019
    Randomized trial12 participantsEnergy forCitrulline
  11. Synergistic effects of creatine, carbs, protein on repeated sprint performance.
    Wang Y; Wei H; Cheng X; Chen Z · Scientific reports · 2026
    Randomized trial60 participantsEnergy forCreatine
  12. The Effects of Creatine Monohydrate Supplementation on Recovery from Eccentric Exercise-Induced Muscle Damage: A Double-Blind, Randomized, Placebo-Controlled Trial Considering Sex and Age Differences.
    Yamaguchi S; Inami T; Nishioka T; Morito A; Ishiyama K; Murayama M · Nutrients · 2025
    Randomized trial40 participantsEnergy forCreatine
  13. The Effect of Prior Creatine Intake for 28 Days on Accelerated Recovery from Exercise-Induced Muscle Damage: A Double-Blind, Randomized, Placebo-Controlled Trial.
    Yamaguchi S; Inami T; Ishida H; Morito A; Yamada S; Nagata N; Murayama M · Nutrients · 2024
    Randomized trial20 participantsEnergy forCreatine
  14. Creatine supplementation attenuates the rate of fatigue development during intermittent isometric exercise performed above end-test torque.
    Abdalla LHP; Broxterman RM; Greco CC; Denadai BS · Experimental physiology · 2021
    Randomized trial16 participantsEnergy forCreatine
  15. The effect of continuous low dose creatine supplementation on force, power, and total work.
    Burke DG; Silver S; Holt LE; Smith Palmer T; Culligan CJ; Chilibeck PD · International journal of sport nutrition and exercise metabolism · 2000
    Randomized trial41 participantsEnergy forCreatine
  16. Effect of caffeine ingestion on cycling performance: a systematic review and meta-analysis.
    Wu J; Xu K; Yin M; Ding X; Wang T; Zhang Q; Wu X; Xiao N · Frontiers in nutrition · 2026
    Meta-analysis226 participants20 studies pooledFitness forCaffeine
  17. Effects of Caffeine Intake on Endurance Running Performance and Time to Exhaustion: A Systematic Review and Meta-Analysis.
    Wang Z; Qiu B; Gao J; Del Coso J · Nutrients · 2023
    Meta-analysis254 participants21 studies pooledFitness forCaffeine
  18. Acute Effects of Caffeine Supplementation on Movement Velocity in Resistance Exercise: A Systematic Review and Meta-analysis.
    Raya-González J; Rendo-Urteaga T; Domínguez R; Castillo D; Rodríguez-Fernández A; Grgic J · Sports medicine (Auckland, N.Z.) · 2021
    Meta-analysis12 studies pooledFitness forCaffeine
  19. Sex Differences in the Ergogenic Response of Acute Caffeine Intake on Muscular Strength, Power and Endurance Performance in Resistance-Trained Individuals: A Randomized Controlled Trial.
    Montalvo-Alonso JJ; Ferragut C; Del Val-Manzano M; Valadés D; Roberts J; Pérez-López A · Nutrients · 2024
    Randomized trial76 participantsFitness forCaffeine
  20. Can I Have My Coffee and Drink It? A Systematic Review and Meta-analysis to Determine Whether Habitual Caffeine Consumption Affects the Ergogenic Effect of Caffeine.
    Carvalho A; Marticorena FM; Grecco BH; Barreto G; Saunders B · Sports medicine (Auckland, N.Z.) · 2022
    Meta-analysis60 studies pooledFitness forCaffeine
  21. The Effects of Combined Exercise with Citrulline Supplementation on Body Composition and Lower Limb Function of Overweight Older Adults: A Systematic Review and Meta-Analysis.
    Xie S; Li S; Shaharudin S · Journal of sports science & medicine · 2023
    Meta-analysis303 participants7 studies pooledFitness forCitrulline
  22. Effect of High-Intensity Interval Training Combined with L-Citrulline Supplementation on Functional Capacities and Muscle Function in Dynapenic-Obese Older Adults.
    Buckinx F; Gouspillou G; Carvalho LP; Marcangeli V; El Hajj Boutros G; Dulac M; Noirez P; Morais JA; Gaudreau P; Aubertin-Leheudre M · Journal of clinical medicine · 2020
    Randomized trial56 participantsFitness Muscle Gain forCitrulline
  23. Initial Dietary Protein Intake Influence Muscle Function Adaptations in Older Men and Women Following High-Intensity Interval Training Combined with Citrulline.
    Buckinx F; Marcangeli V; Pinheiro Carvalho L; Dulac M; Hajj Boutros G; Gouspillou G; Gaudreau P; Morais J; Noirez P; Aubertin-Leheudre M · Nutrients · 2020
    Randomized trial73 participantsFitness forCitrulline
  24. Effects of Citrulline alone or combined with exercise on muscle mass, muscle strength, and physical performance among older adults: a systematic review.
    Aubertin-Leheudre M; Buckinx F · Current opinion in clinical nutrition and metabolic care · 2021
    Systematic review250 participants6 studies pooledFitness Muscle Gain forCitrulline
  25. Combined Vs. Single Supplementation of L-Citrulline and Sodium Bicarbonate During Sprint Interval Training in Basketball Players: Effects on Physical Performance and Hormonal Adaptations.
    Wang Y; Wang Y; Qian K · Journal of sports science & medicine · 2025
    Randomized trial40 participantsFitness forCitrulline
  26. Creatine in combination with resistance training and improvement in muscle strength: evaluation of a health claim pursuant to Article 13(5) of Regulation (EC) No 1924/2006.
    EFSA Panel on Dietetic Products, Nutrition and Allergies (NDA) · EFSA journal. European Food Safety Authority · 2026
    Guideline / consensusFitness forCreatine
  27. Effect of creatine and weight training on muscle creatine and performance in vegetarians.
    Burke DG; Chilibeck PD; Parise G; Candow DG; Mahoney D; Tarnopolsky M · Medicine and science in sports and exercise · 2004
    Randomized trial42 participantsFitness forCreatine
  28. Long-term creatine intake is beneficial to muscle performance during resistance training.
    Vandenberghe K; Goris M; Van Hecke P; Van Leemputte M; Vangerven L; Hespel P · Journal of applied physiology (Bethesda, Md. : 1985) · 1998
    Randomized trial19 participantsFitness forCreatine
  29. Effects of Combined Versus Single Supplementation of Creatine, Beta-Alanine, and L-Citrulline During Short Sprint Interval Training on Basketball Players' Performance: A Double-Blind Randomized Placebo-Controlled Trial.
    Li M; Sheykhlouvand M · International journal of sports physiology and performance · 2025
    Randomized trial48 participantsFitness forCreatine
  30. The Additive Effects of Creatine Supplementation and Exercise Training in an Aging Population: A Systematic Review of Randomized Controlled Trials.
    Stares A; Bains M · Journal of geriatric physical therapy (2001) · 2021
    Systematic review17 studies pooledFitness forCreatine
  31. Effects of modafinil and caffeine on night-time vigilance of air force crewmembers: A randomized controlled trial.
    Wingelaar-Jagt YQ; Bottenheft C; Riedel WJ; Ramaekers JG · Journal of psychopharmacology (Oxford, England) · 2023
    Randomized trial32 participantsMental Focus forCaffeine
  32. Acute effects of caffeine on attention: a comparison of non-consumers and withdrawn consumers.
    Smith AP; Christopher G; Sutherland D · Journal of psychopharmacology (Oxford, England) · 2013
    Randomized trial70 participantsMental Focus forCaffeine
  33. Performance and alertness effects of caffeine, dextroamphetamine, and modafinil during sleep deprivation.
    Wesensten NJ; Killgore WD; Balkin TJ · Journal of sleep research · 2006
    Randomized trial48 participantsMental Focus forCaffeine
  34. Effects of caffeine on mood and performance: a study of realistic consumption.
    Brice CF; Smith AP · Psychopharmacology · 2003
    Clinical trial24 participantsMental Focus forCaffeine
  35. Effects of caffeine or diphenhydramine on visual vigilance.
    Fine BJ; Kobrick JL; Lieberman HR; Marlowe B; Riley RH; Tharion WJ · Psychopharmacology · 1995
    Randomized trial24 participantsMental Focus forCaffeine
  36. The Effects of 8-Week Creatine Hydrochloride and Creatine Ethyl Ester Supplementation on Cognition, Clinical Outcomes, and Brain Creatine Levels in Perimenopausal and Menopausal Women (CONCRET-MENOPA): A Randomized Controlled Trial.
    Korovljev D; Ostojic J; Panic J; Ranisavljev M; Todorovic N; Nedeljkovic D; Kuzmanovic J; Vranes M; Stajer V; Ostojic SM · Journal of the American Nutrition Association · 2026
    Randomized trial36 participantsMental Focus forCreatine
  37. Creatine and Cognition in Aging: A Systematic Review of Evidence in Older Adults.
    Marshall S; Kitzan A; Wright J; Bocicariu L; Nagamatsu LS · Nutrition reviews · 2026
    Systematic review1,542 participants6 studies pooledMental Focus forCreatine
  38. Effect of creatine supplementation and sleep deprivation, with mild exercise, on cognitive and psychomotor performance, mood state, and plasma concentrations of catecholamines and cortisol.
    McMorris T; Harris RC; Swain J; Corbett J; Collard K; Dyson RJ; Dye L; Hodgson C; Draper N · Psychopharmacology · 2006
    Clinical trial19 participantsMental Focus forCreatine
  39. Six-Week Supplementation with Creatine in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS): A Magnetic Resonance Spectroscopy Feasibility Study at 3 Tesla.
    Godlewska BR; Sylvester AL; Emir UE; Sharpley AL; Clarke WT; Martens MAG; Cowen PJ · Nutrients · 2024
    Single-arm trial14 participantsMental Focus forCreatine
  40. The effects of creatine supplementation on cognitive function in adults: a systematic review and meta-analysis.
    Xu C; Bi S; Zhang W; Luo L · Frontiers in nutrition · 2026
    Meta-analysis492 participants16 studies pooledMental Focus forCreatine
  41. A Randomized Study to Examine the Ability of a Caffeine-Based Energy Drink to Impact Energy Expenditure, Fat Oxidation, and Cognitive Performance.
    Krieger J; Schrautemeier A; Hagele A; Gaige C; Mennemeyer O; Tolbert S; Iannotti J; Kerksick C; Noonan C; Mumford P · Nutrients · 2025
    Randomized trial60 participantsMetabolism Boost forCaffeine
  42. Oolong tea increases metabolic rate and fat oxidation in men.
    Rumpler W; Seale J; Clevidence B; Judd J; Wiley E; Yamamoto S; Komatsu T; Sawaki T; Ishikura Y; Hosoda K · The Journal of nutrition · 2001
    Randomized trial12 participantsMetabolism Boost forCaffeine
  43. Effect of caffeine intake on fat oxidation rate during exercise: is there a dose-response effect?
    Gutiérrez-Hellín J; Aguilar-Navarro M; Ruiz-Moreno C; Muñoz A; Varillas-Delgado D; Amaro-Gahete FJ; Del Coso J · European journal of nutrition · 2023
    Randomized trial18 participantsMetabolism Boost forCaffeine
  44. Comparison of changes in energy expenditure and body temperatures after caffeine consumption.
    Koot P; Deurenberg P · Annals of nutrition & metabolism · 1995
    Randomized trial12 participantsMetabolism Boost forCaffeine
  45. Caffeine Increases Work Done above Critical Power, but Not Anaerobic Work.
    Silveira R; Andrade-Souza VA; Arcoverde L; Tomazini F; Sansonio A; Bishop DJ; Bertuzzi R; Lima-Silva AE · Medicine and science in sports and exercise · 2018
    Randomized trial9 participantsMetabolism Boost forCaffeine
  46. Effects of Acute Ingestion of Caffeine Capsules on Muscle Strength and Muscle Endurance: A Systematic Review and Meta-Analysis.
    Wu W; Chen Z; Zhou H; Wang L; Li X; Lv Y; Sun T; Yu L · Nutrients · 2024
    Meta-analysis14 studies pooledMuscle Gain forCaffeine
  47. Acute caffeine intake improves muscular strength, power, and endurance performance, reversing the time-of-day effect regardless of muscle activation level in resistance-trained males: a randomized controlled trial.
    Montalvo-Alonso JJ; Del Val-Manzano M; Cerezo-Telléz E; Ferragut C; Valadés D; Rodríguez-Falces J; Pérez-López A · European journal of applied physiology · 2025
    Randomized trial13 participantsMuscle Gain forCaffeine
  48. Wake up and smell the coffee: caffeine supplementation and exercise performance-an umbrella review of 21 published meta-analyses.
    Grgic J; Grgic I; Pickering C; Schoenfeld BJ; Bishop DJ; Pedisic Z · British journal of sports medicine · 2020
    Systematic review21 studies pooledMuscle Gain forCaffeine
  49. Effects of caffeine intake on muscle strength and power: a systematic review and meta-analysis.
    Grgic J; Trexler ET; Lazinica B; Pedisic Z · Journal of the International Society of Sports Nutrition · 2018
    Meta-analysis20 studies pooledMuscle Gain forCaffeine
  50. Caffeine increases strength and power performance in resistance-trained females during early follicular phase.
    Norum M; Risvang LC; Bjørnsen T; Dimitriou L; Rønning PO; Bjørgen M; Raastad T · Scandinavian journal of medicine & science in sports · 2021
    Randomized trial15 participantsMuscle Gain forCaffeine
  51. Impact of L-citrulline supplementation and whole-body vibration training on arterial stiffness and leg muscle function in obese postmenopausal women with high blood pressure.
    Figueroa A; Alvarez-Alvarado S; Ormsbee MJ; Madzima TA; Campbell JC; Wong A · Experimental gerontology · 2015
    Randomized trial41 participantsMuscle Gain forCitrulline
  52. Citrulline Supplementation Improves Microvascular Function and Muscle Strength in Middle-Aged and Older Adults with Type 2 Diabetes.
    Figueroa A; Dillon KN; Levitt DE; Kang Y · Nutrients · 2025
    Randomized trial16 participantsMuscle Gain forCitrulline
  53. Citrulline stimulates muscle protein synthesis in the post-absorptive state in healthy people fed a low-protein diet - A pilot study.
    Jourdan M; Nair KS; Carter RE; Schimke J; Ford GC; Marc J; Aussel C; Cynober L · Clinical nutrition (Edinburgh, Scotland) · 2016
    Randomized trial8 participantsMuscle Gain forCitrulline
  54. The Effect of Creatine Supplementation on Resistance Training-Based Changes to Body Composition: A Systematic Review and Meta-analysis.
    Desai I; Wewege MA; Jones MD; Clifford BK; Pandit A; Kaakoush NO; Simar D; Hagstrom AD · Journal of strength and conditioning research · 2025
    Meta-analysis362 participants12 studies pooledMuscle Gain Weight Loss forCreatine
  55. Effects of Creatine Supplementation and Resistance Training on Muscle Strength Gains in Adults <50 Years of Age: A Systematic Review and Meta-Analysis.
    Wang Z; Qiu B; Li R; Han Y; Petersen C; Liu S; Zhang Y; Liu C; Candow DG; Del Coso J · Nutrients · 2024
    Meta-analysis509 participants23 studies pooledMuscle Gain forCreatine
  56. Comparative Effects of Dietary Protein, Creatine, and Omega-3 Supplementation on Muscle Strength, Endurance, and Recovery in Trained Athletes: A Systematic Review and Network Meta-Analysis.
    Wang Z; Qin G; Kim BM · Nutrients · 2026
    Meta-analysis1,211 participants35 studies pooledMuscle Gain forCreatine
  57. Effect of creatine supplementation during resistance training on lean tissue mass and muscular strength in older adults: a meta-analysis.
    Chilibeck PD; Kaviani M; Candow DG; Zello GA · Open access journal of sports medicine · 2020
    Meta-analysis721 participants22 studies pooledMuscle Gain forCreatine
  58. Creatine supplementation during resistance training in older adults-a meta-analysis.
    Devries MC; Phillips SM · Medicine and science in sports and exercise · 2014
    Meta-analysis357 participantsMuscle Gain forCreatine
  59. Effects of caffeine on alertness.
    Zwyghuizen-Doorenbos A; Roehrs TA; Lipschutz L; Timms V; Roth T · Psychopharmacology · 1990
    Randomized trial24 participantsProductivity Boost forCaffeine
  60. Effects of Different Sources of Low-Dose Caffeine on Mood/Arousal and Cognitive Performance.
    Irwin C; McCartney D; Grant G; Delang N; Bartrim K; Cox GR; Desbrow B · Perceptual and motor skills · 2023
    Randomized trial22 participantsProductivity Boost forCaffeine
  61. Effects of caffeine, sleep loss, and stress on cognitive performance and mood during U.S. Navy SEAL training. Sea-Air-Land.
    Lieberman HR; Tharion WJ; Shukitt-Hale B; Speckman KL; Tulley R · Psychopharmacology · 2003
    Randomized trial68 participantsProductivity Boost forCaffeine
  62. A review of caffeine's effects on cognitive, physical and occupational performance.
    McLellan TM; Caldwell JA; Lieberman HR · Neuroscience and biobehavioral reviews · 2017
    Narrative reviewProductivity Boost forCaffeine
  63. Acute caffeine supplementation as a nutrition-based strategy to mitigate sleep-loss-related cognitive and operational performance impairments in military personnel: a systematic review and meta-analysis.
    Wang R; Wang W; Meng L; Hao G; Gu G · Frontiers in nutrition · 2026
    Meta-analysis7 studies pooledProductivity Boost forCaffeine
  64. Creatine supplementation enhances corticomotor excitability and cognitive performance during oxygen deprivation.
    Turner CE; Byblow WD; Gant N · The Journal of neuroscience : the official journal of the Society for Neuroscience · 2015
    Randomized trial15 participantsProductivity Boost forCreatine
  65. Creatine supplementation and cognitive performance in elderly individuals.
    McMorris T; Mielcarz G; Harris RC; Swain JP; Howard A · Neuropsychology, development, and cognition. Section B, Aging, neuropsychology and cognition · 2008
    Randomized trial32 participantsProductivity Boost forCreatine
  66. The effects of creatine supplementation on cognitive performance-a randomised controlled study.
    Sandkühler JF; Kersting X; Faust A; Königs EK; Altman G; Ettinger U; Lux S; Philipsen A; Müller H; Brauner J · BMC medicine · 2023
    Randomized trial123 participantsProductivity Boost forCreatine
  67. Single dose creatine improves cognitive performance and induces changes in cerebral high energy phosphates during sleep deprivation.
    Gordji-Nejad A; Matusch A; Kleedörfer S; Jayeshkumar Patel H; Drzezga A; Elmenhorst D; Binkofski F; Bauer A · Scientific reports · 2024
    Randomized trialProductivity Boost forCreatine
  68. Dietary supplementation of creatine monohydrate reduces the human fMRI BOLD signal.
    Hammett ST; Wall MB; Edwards TC; Smith AT · Neuroscience letters · 2010
    Non-randomized trialProductivity Boost forCreatine
  69. Changes in caffeine intake and long-term weight change in men and women.
    Lopez-Garcia E; van Dam RM; Rajpathak S; Willett WC; Manson JE; Hu FB · The American journal of clinical nutrition · 2006
    Cohort study58,157 participantsWeight Loss forCaffeine
  70. Does caffeine ingestion before a short-term sprint interval training promote body fat loss?
    Ferreira GA; Felippe LC; Bertuzzi R; Bishop DJ; Ramos IS; De-Oliveira FR; Lima-Silva AE · Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas · 2020
    Randomized trial20 participantsWeight Loss forCaffeine
  71. Eight Weeks of Sprint Interval Training With Adding Caffeine Ingestion Leads to Greater Improvements in Health-Related Physiological Parameters in Obese Male Adults.
    Zhiang J; Song Q · Physiological research · 2026
    Randomized trial30 participantsWeight Loss forCaffeine
  72. Caffeine treatment prevented from weight regain after calorie shifting diet induced weight loss.
    Davoodi SH; Hajimiresmaiel SJ; Ajami M; Mohseni-Bandpei A; Ayatollahi SA; Dowlatshahi K; Javedan G; Pazoki-Toroudi H · Iranian journal of pharmaceutical research : IJPR · 2014
    Non-randomized trial60 participantsWeight Loss forCaffeine
  73. The effects of caffeine intake on weight loss: a systematic review and dos-response meta-analysis of randomized controlled trials.
    Tabrizi R; Saneei P; Lankarani KB; Akbari M; Kolahdooz F; Esmaillzadeh A; Nadi-Ravandi S; Mazoochi M; Asemi Z · Critical reviews in food science and nutrition · 2020
    Meta-analysis606 participants13 studies pooledWeight Loss forCaffeine
  74. Changes in Fat Mass Following Creatine Supplementation and Resistance Training in Adults ≥50 Years of Age: A Meta-Analysis.
    Forbes SC; Candow DG; Krentz JR; Roberts MD; Young KC · Journal of functional morphology and kinesiology · 2021
    Meta-analysis609 participants19 studies pooledWeight Loss forCreatine
  75. Effects of creatine supplementation with and without exercise and diet intervention on body composition, cognitive function, and markers of health in middle-aged and older adults.
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