Niacinamide 1000 mg

Niacinamide 1000 mg

Nature's Life4.6 (309 ratings)
Format:Tablet Quantity: 100 Tablet(s) · 100 servings
$12.19 $0.12 per serving

About this product

Niacinamide supports vitamin B3 status without the characteristic flush of nicotinic acid. Its clearest fit is nutritional or skin-barrier support rather than lipid-focused cardiovascular use.

The supplied label repeats the same large amount under niacinamide and vitamin B3. That likely describes one ingredient, but the presentation makes the true total harder to confirm.

The amount is far beyond routine nutrient needs and deserves more caution than a standard B-complex. Low serving cost does not offset the need to consider liver, glucose, and digestive tolerance during prolonged use.

Who is it for
  • Adults specifically directed to use high-dose niacinamide
  • People seeking non-flushing vitamin B3
  • Users focused on skin-barrier nutrition
Best for
  • Niacinamide supplementation
  • Non-flushing vitamin B3 intake
  • Short, clinician-guided high-dose use

Pros

  • Clearly named niacinamide form
  • No typical nicotinic-acid flush
  • Long supply at low serving cost

Cons

  • Amount is excessive for routine nutrition
  • Duplicate ingredient lines cloud the total
  • Weak fit for lipid-focused heart support

Warnings

  • One gram of niacinamide may cause nausea, diarrhea, or headache, especially on an empty stomach.
  • Prolonged high-dose use may affect liver enzymes or glucose control and is best monitored professionally.
  • Do not add the duplicated label lines together without confirming the actual serving amount.

Product analysis

72 out of 100
A high-dose niacinamide product that fits skin and vitamin B3 support better than heart goals. The aggressive amount and duplicate label entries are the main concerns.

AI assessment of the formula, label and price. How scoring works

Nutrient quality57

Niacinamide is a clear and well-understood non-flushing form. The amount is far above general nutritional and common skin-support ranges.

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Ingredient transparency79

The core amount is shown, but parts of the active labeling remain ambiguous. The supplied data does not include a complete inactive ingredient list.

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Customer satisfaction65

The aggregate satisfaction measure is strong and supported by adequate volume. Missing feedback themes leave recurring complaints and purpose fit uncertain.

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Value for money85

The price is reasonable for the formula quality and dose. Each serving provides good cost efficiency.

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Format
Tablet
Container
100 Tablet(s)
Per serving
$0.12
Customer rating
4.6 · 309 ratings
Report analysis

Ingredients

IngredientAmount per servingScore
Niacin (Niacinamide)
1000 mg 82
Adults 18–50 Vegetarian
Report overview
Niacin (Niacinamide) · 1000 mg OverallScore82
A+ Active Ingredient Quality & BioavailabilityB Dose, Safety & Label TransparencyC Value
This tablet names niacinamide and carries a no-flush label. Its listed 1,000 mg is above the supplied 100–500 mg niacinamide range, while the per-serving cost is moderate.
How this ingredient is rated

Active Ingredient Quality & Bioavailability100

Niacinamide is the sole identified form, and the saved goal is skin support rather than cardiovascular or NAD+ support.
Niacin Form & Goal Alignment
The saved skin-support goal matches niacinamide in the supplied context.
Precursor Source Quality
No advanced NAD+ claim is recorded; niacinamide is the listed source.

Dose, Safety & Label Transparency75

The form is named and a no-flush label is present, though the listed amount is above the supplied range.
Clarity of Chemical Form
The label explicitly identifies niacinamide.
Form-Specific Dosage Efficacy
The 1,000 mg amount exceeds the supplied 100–500 mg niacinamide range.
Flush Risk & Safety Labeling
A no-flush label is recorded in the saved facts.

Value60

The per-serving cost is in a moderate range.
Price Per Effective Serving
The cost per serving is moderate for niacinamide.
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Sources

Published studies used for the product analysis and the top-ranked studies for each ingredient and goal.

  1. Effect of niacin therapy on cardiovascular outcomes in patients with coronary artery disease.
    Duggal JK; Singh M; Attri N; Singh PP; Ahmed N; Pahwa S; Molnar J; Singh S; Khosla S; Arora R · Journal of cardiovascular pharmacology and therapeutics · 2010
    Meta-analysis5,137 participants7 studies pooledHeart Health forNiacin
  2. Role of Niacin in Current Clinical Practice: A Systematic Review.
    Garg A; Sharma A; Krishnamoorthy P; Garg J; Virmani D; Sharma T; Stefanini G; Kostis JB; Mukherjee D; Sikorskaya E · The American journal of medicine · 2017
    Meta-analysis35,206 participants13 studies pooledHeart Health forNiacin
  3. Relationship of lipoproteins to cardiovascular events: the AIM-HIGH Trial (Atherothrombosis Intervention in Metabolic Syndrome With Low HDL/High Triglycerides and Impact on Global Health Outcomes).
    Guyton JR; Slee AE; Anderson T; Fleg JL; Goldberg RB; Kashyap ML; Marcovina SM; Nash SD; O'Brien KD; Weintraub WS; Xu P; Zhao XQ; Boden WE · Journal of the American College of Cardiology · 2013
    Randomized trial3,414 participantsHeart Health Cardiovascular Support forNiacin
  4. Assessment of the Role of Niacin in Managing Cardiovascular Disease Outcomes: A Systematic Review and Meta-analysis.
    D'Andrea E; Hey SP; Ramirez CL; Kesselheim AS · JAMA network open · 2020
    Meta-analysis35,760 participants17 studies pooledHeart Health forNiacin
  5. Exploring the Cardiovascular Impacts of Oral Nicotinamide: A Comprehensive Narrative Review.
    Shoukfeh R; Tisack AM; Lim HW; Mohammad TF · Journal of drugs in dermatology : JDD · 2025
    Narrative reviewHeart Health forNiacin
  6. The ARBITER 6-HALTS Trial (Arterial Biology for the Investigation of the Treatment Effects of Reducing Cholesterol 6-HDL and LDL Treatment Strategies in Atherosclerosis): final results and the impact of medication adherence, dose, and treatment duration.
    Villines TC; Stanek EJ; Devine PJ; Turco M; Miller M; Weissman NJ; Griffen L; Taylor AJ · Journal of the American College of Cardiology · 2010
    Randomized trial315 participantsHeart Health forNiacin
  7. Niacinamide: A B vitamin that improves aging facial skin appearance.
    Bissett DL; Oblong JE; Berge CA · Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.] · 2005
    Randomized trial50 participantsSkin Health forNiacin
  8. The effect of niacinamide on reducing cutaneous pigmentation and suppression of melanosome transfer.
    Hakozaki T; Minwalla L; Zhuang J; Chhoa M; Matsubara A; Miyamoto K; Greatens A; Hillebrand GG; Bissett DL; Boissy RE · The British journal of dermatology · 2002
    Randomized trial138 participantsSkin Health forNiacin
  9. Effect of Nicotinamide in Skin Cancer and Actinic Keratoses Chemoprophylaxis, and Adverse Effects Related to Nicotinamide: A Systematic Review and Meta-Analysis.
    Mainville L; Smilga AS; Fortin PR · Journal of cutaneous medicine and surgery · 2022
    Meta-analysis3,039 participants29 studies pooledSkin Health forNiacin
  10. Nicotinamide for Skin-Cancer Chemoprevention in Transplant Recipients.
    Allen NC; Martin AJ; Snaidr VA; Eggins R; Chong AH; Fernandéz-Peñas P; Gin D; Sidhu S; Paddon VL; Banney LA; Lim A; Upjohn E; Schaider H; Ganhewa AD; Nguyen J; McKenzie CA; Prakash S; McLean C; Lochhead A; Ibbetson J; Dettrick A; Landgren A; Allnutt KJ; Allison C; Davenport RB; Mumford BP; Wong B; Stagg B; Tedman A; Gribbin H; Edwards HA; De Rosa N; Stewart T; Doolan BJ; Kok Y; Simpson K; Low ZM; Kovitwanichkanont T; Scolyer RA; Dhillon HM; Vardy JL; Chadban SJ; Bowen DG; Chen AC; Damian DL · The New England journal of medicine · 2023
    Randomized trial158 participantsSkin Health forNiacin
  11. Evaluation of anti-wrinkle effects of a novel cosmetic containing niacinamide.
    Kawada A; Konishi N; Oiso N; Kawara S; Date A · The Journal of dermatology · 2008
    Randomized trial30 participantsSkin Health forNiacin
  12. A Foodborne Outbreak Traced to Niacin Overenrichment.
    Hudson PJ; Vogt RL · Journal of food protection · 2023
    Case-control study21 participantsSkin Health forNiacin
  13. Nicotinamide for Skin Cancer Chemoprevention.
    Breglio KF; Knox KM; Hwang J; Weiss R; Maas K; Zhang S; Yao L; Madden C; Xu Y; Hartman RI; Wheless L · JAMA dermatology · 2025
    Cohort study33,822 participantsSkin Health forNiacin
  14. Chemoprevention of keratinocyte carcinomas and actinic keratoses in adults who were immunocompetent: a systematic review.
    Susanto A; Morgan E; Lindsay D; Collins LG · Clinical and experimental dermatology · 2026
    Systematic review7,355 participants11 studies pooledSkin Health forNiacin
  15. The current state of niacin in cardiovascular disease prevention: a systematic review and meta-regression.
    Lavigne PM; Karas RH · Journal of the American College of Cardiology · 2013
    Meta-analysis9,959 participants11 studies pooledCardiovascular Support forNiacin
  16. Effects of niacin on apo A1 and B levels: a systematic review and meta-analysis of randomised controlled trials.
    Saboori S; Yousefi Rad E; Tammam J; Thondre PS; Coe S · The British journal of nutrition · 2024
    Meta-analysis12 studies pooledCardiovascular Support forNiacin
  17. Niacin improves lipid profile but not endothelial function in patients with coronary artery disease on high dose statin therapy.
    Philpott AC; Hubacek J; Sun YC; Hillard D; Anderson TJ · Atherosclerosis · 2013
    Randomized trial66 participantsCardiovascular Support forNiacin
  18. Supplemental Vitamins and Minerals for Cardiovascular Disease Prevention and Treatment: JACC Focus Seminar.
    Jenkins DJA; Spence JD; Giovannucci EL; Kim YI; Josse RG; Vieth R; Sahye-Pudaruth S; Paquette M; Patel D; Blanco Mejia S; Viguiliouk E; Nishi SK; Kavanagh M; Tsirakis T; Kendall CWC; Pichika SC; Sievenpiper JL · Journal of the American College of Cardiology · 2021
    Meta-analysisCardiovascular Support forNiacin
  19. Effect of niacin on lipid and lipoprotein levels and glycemic control in patients with diabetes and peripheral arterial disease: the ADMIT study: A randomized trial. Arterial Disease Multiple Intervention Trial.
    Elam MB; Hunninghake DB; Davis KB; Garg R; Johnson C; Egan D; Kostis JB; Sheps DS; Brinton EA · JAMA · 2000
    Randomized trial468 participantsCardiovascular Support forNiacin