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Kyolic Vitamin E Cayenne Hawthorn

Kyolic
4.8
★ ★ ★ ★ ★
(479 ratings)
Vitamin E 200 IU
Hawthorn 100 mg
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Score79
A large-supply vitamin E and aged-garlic formula with clear dosing. Hawthorn quality and amount remain too weak for dedicated use.
How scoring works
Quantity:300 Capsule(s) • (150 servings)
Goals:
Anti-Inflammatory Support
Cardiovascular Support

Score 79

A large-supply vitamin E and aged-garlic formula with clear dosing. Hawthorn quality and amount remain too weak for dedicated use.
How scoring works

Also available as

1 option
200 servings Hawthorn 100 mg, E 200 IU • 200 Capsule(s) • 100 servings $27.56 ($0.27 per serving)
$38.44($0.25 per serving)
iHerb
$ 38.44
Vitacost
$ 38.44
Report prices

Analysis

Natural vitamin E and 600 mg aged garlic create a useful antioxidant and cardiovascular-support base. The formula is more convincing for those ingredients than for its smaller botanical additions.

Hawthorn is below the preferred amount for ordinary berry powder and lacks species or marker standardization. Cayenne is also present at a modest amount without potency detail.

The 150-serving supply supports convenient long-term use and every active amount is disclosed. Missing broader vitamin E isomers and ocular nutrients keep the formula narrow for vision support.

Who is it for
  • Long-term users of vitamin E and aged garlic
  • Adults seeking general cardiovascular support
  • People comfortable with a multi-botanical capsule
Best for
  • Natural vitamin E intake
  • Aged garlic support
  • Large-supply supplementation

Pros

  • Natural vitamin E form
  • Substantial aged garlic amount
  • All actives are quantified
  • Large 150-serving supply

Cons

  • Low hawthorn amount
  • No hawthorn standardization
  • Limited vitamin E isomer breadth
  • Weak vision-specific coverage

Warnings

  • Vitamin E and aged garlic may increase bleeding tendency with anticoagulant or antiplatelet medicines
  • Hawthorn may interact with blood pressure or heart medicines
  • Cayenne can worsen reflux or stomach irritation in sensitive users

Nutrient quality

82 Highest impact

Natural-form vitamin E and a substantial aged-garlic amount provide a useful core. Hawthorn and cayenne add coherent support, though their modest unstandardized amounts limit depth.

Ingredient transparency

76 High impact

All active amounts are clearly disclosed without a proprietary blend. Hawthorn species, extract markers, complete directions, and capsule excipients are not supplied.

Customer satisfaction

70 High impact

The supplied satisfaction metric is strong and response volume is substantial. Specific firsthand feedback was not supplied, so recurring complaints and purpose alignment remain uncertain.

Value for money

87 Highest impact

Natural vitamin E and aged garlic provide good quality at an accessible serving cost. The larger package compares favorably for broad cardiovascular support despite weak hawthorn standardization.

Report analysis

Goals

Anti-Inflammatory Support
Anti-Inflammatory Support
Impact
Highest effect
B+ Goal FitA- Strength of SupportB+ CoverageA- Formula Quality
Vitamin E · 200 IU

Natural vitamin E supports membrane antioxidant defense, while aged garlic adds a separate pathway related to oxidative and inflammatory signaling. Hawthorn and cayenne provide secondary cardiovascular botanicals, creating a broader but less directly targeted formula.

Vitamin E and aged garlic are present in meaningful amounts, but the botanical extracts lack active-marker standardization. Vitamin E, aged garlic, and cayenne may together increase bleeding tendency with anticoagulant or antiplatelet medicines, so that combination deserves medication-specific review.

Study evidence
Vitamin E Supportive 20 studies
Cardiovascular Support
Cardiovascular Support
Impact
High effect
B- Goal FitC Strength of SupportC CoverageB- Formula Quality
Vitamin E · 200 IUHawthorn · 100 mg

Natural vitamin E and aged garlic provide the strongest cardiovascular support in this blend. Hawthorn and cayenne add relevant ideas but are present at modest, non-standardized amounts.

The formula covers antioxidant and vascular pathways with clear ingredient amounts. Hawthorn lacks species and active-compound details, so its practical contribution is uncertain.

Study evidence
Hawthorn Supportive 28 studies
Vitamin E Mixed 79 studies

Ingredients

IngredientAmount per serving
Vitamin E (D-Alpha-Tocopheryl Succinate)
 200 IU
Aged Garlic extract powder
600 mg
Hawthorn Berry
100 mg
Cayenne Pepper
20 mg
Gluten Free Adults 18–50 Dairy Free Sugar Free
Report overview
Vitamin E (D-Alpha-Tocopheryl Succinate) · 200 IU OverallScore78
D Active Ingredient Quality & BioavailabilityA+ Dose, Safety & Label TransparencyA+ Value

Natural d-alpha vitamin E offers better biological activity than a synthetic form, but the formula lacks broader vitamin E isomers. The amount falls within the established range for general antioxidant support. Cost efficiency is favorable for the natural form provided.

View ingredientView products
Hawthorn · 100 mg OverallScore45
F Active Ingredient Quality & BioavailabilityC- Dose, Safety & Label TransparencyD- Value

The 100 mg hawthorn berry dose is well below the effective range used for non-standardized powder. The label also omits the botanical species and any concentration or active-compound standardization, limiting confidence in ingredient quality. Its low serving cost is appealing, but the small dose makes it poor value for focused hawthorn use.

View ingredientView products
Loading alternative details
86 Performance

Hawthorn Extract 300 mg

NOW
The ingredient profile offers a potentially stronger fit for the overlapping nutrient needs than the original. Standardized extract plus whole berry provides substantial hawthorn depth at unusually low cost.
85 Performance

Hawthorn 300 mg

Nature's Way
The ingredient profile offers a potentially stronger fit for the overlapping nutrient needs than the original. A meaningful leaf-and-flower extract plus whole hawthorn gives the formula strong focus and dose quality.
84 Performance

Hawthorn 358 mg

Nature's Answer
The ingredient profile offers a potentially stronger fit for the overlapping nutrient needs than the original. Unusually complete source identification and a meaningful standardized dose support high ingredient quality.
83 Budget

Natural E Liquid

NOW
The supplied serving-cost data indicates a less expensive option than the original. Natural d-alpha-tocopherol provides a modest maintenance amount in an exceptionally economical liquid.
81 Budget

Hawthorn Berry 565 mg

Swanson
The supplied serving-cost data indicates a less expensive option than the original. A simple moderate-dose hawthorn powder offers very low-cost targeted use.
77 Budget

Hawthorn Berries 565 mg

Herbal Secrets
The supplied serving-cost data indicates a less expensive option than the original. A useful berry-powder amount offers simple targeted support at very low cost.
86 Value

Extra Strength Hawthorn Extract 600 mg

NOW
The balance of formulation quality and serving efficiency makes it a practical value candidate compared with the original. A substantial standardized hawthorn extract provides focused and economical cardiovascular support.
84 Value

Mixed Vitamin E 400 IU

Natural Factors
The balance of formulation quality and serving efficiency makes it a practical value candidate compared with the original. Natural d-alpha vitamin E with mixed tocopherols offers broader antioxidant coverage than alpha alone at a favorable serving cost.
84 Value

Full Spectrum Hawthorn Extract

Planetary Herbals
The balance of formulation quality and serving efficiency makes it a practical value candidate compared with the original. Leaf-and-flower sourcing, vitexin standardization, and a substantial dose make the formula easy to evaluate.
Report alternatives

Sources

Published studies used for the product analysis and the top-ranked studies for each ingredient and goal.

  1. A systematic review and meta-analysis on the impact of oral vitamin E supplementation on apolipoproteins A1 and B100.
    Hamedi-Kalajahi F; Zarezadeh M; Dehghani A; Musazadeh V; Kolahi A; Shabbidar S; Djafarian K · Clinical nutrition ESPEN · 2022
    Meta-analysis1,284 participants7 studies pooledCardiovascular Support forVitamin E
  2. Alpha-tocopherol supplementation in healthy individuals reduces low-density lipoprotein oxidation but not atherosclerosis: the Vitamin E Atherosclerosis Prevention Study (VEAPS).
    Hodis HN; Mack WJ; LaBree L; Mahrer PR; Sevanian A; Liu CR; Liu CH; Hwang J; Selzer RH; Azen SP; VEAPS Research Group · Circulation · 2002
    Randomized trialCardiovascular Support forVitamin E
  3. The effect of vitamin E on blood pressure in individuals with type 2 diabetes: a randomized, double-blind, placebo-controlled trial.
    Ward NC; Wu JH; Clarke MW; Puddey IB; Burke V; Croft KD; Hodgson JM · Journal of hypertension · 2007
    Randomized trial58 participantsCardiovascular Support forVitamin E
  4. Supplementation with vitamin E alone is associated with reduced myocardial infarction: a meta-analysis.
    Loffredo L; Perri L; Di Castelnuovo A; Iacoviello L; De Gaetano G; Violi F · Nutrition, metabolism, and cardiovascular diseases : NMCD · 2016
    Meta-analysis16 studies pooledCardiovascular Support forVitamin E
  5. Effect of oral vitamin E (alpha-tocopherol) supplementation on vascular endothelial function in Type 2 diabetes mellitus.
    Gazis A; White DJ; Page SR; Cockcroft JR · Diabetic medicine : a journal of the British Diabetic Association · 1999
    Clinical trial69 participantsCardiovascular Support forVitamin E
  6. Effects of Vitamin C and/or E Supplementation on Glycemic Control and Cardiovascular Risk Factors in Type 2 Diabetes: A Systematic Review and Subgroup Meta-analysis.
    Aragón-Vela J; Huertas JR; Casuso RA · Nutrition reviews · 2026
    Meta-analysis1,425 participants52 studies pooledCardiovascular Support forVitamin E
  7. Interventional study with vitamin E in cardiovascular disease and meta-analysis.
    Violi F; Nocella C; Loffredo L; Carnevale R; Pignatelli P · Free radical biology & medicine · 2022
    Meta-analysisCardiovascular Support forVitamin E
  8. Effect of vitamin E on cardiometabolic factors in paediatric metabolic dysfunction-associated steatotic liver disease: a systematic review with meta-analysis.
    Pam P; Musazadeh V; Mahmoudinezhad M; Panahiyan P; Mansoori MA; Zarrin R; Faghfouri AH · The British journal of nutrition · 2026
    Meta-analysis665 participants11 studies pooledCardiovascular Support forVitamin E
  9. The effects of tocotrienol supplementation on lipid profile: A meta-analysis of randomized controlled trials.
    Zuo S; Wang G; Han Q; Xiao H; O Santos H; Avelar Rodriguez D; Khani V; Tang J · Complementary therapies in medicine · 2021
    Meta-analysis15 studies pooledCardiovascular Support forVitamin E
  10. Vitamin E ameliorates blood cholesterol level and alters gut microbiota composition: A randomized controlled trial.
    Chen B; Li Y; Li Z; Hu X; Zhen H; Chen H; Nie C; Hou Y; Zhu S; Xiao L; Li T · Nutrition, metabolism, and cardiovascular diseases : NMCD · 2025
    Randomized trial90 participantsCardiovascular Support forVitamin E
  11. Effects of delta-tocotrienol supplementation on Glycemic Control, oxidative stress, inflammatory biomarkers and miRNA expression in type 2 diabetes mellitus: A randomized control trial.
    Mahjabeen W; Khan DA; Mirza SA; Pervez MA · Phytotherapy research : PTR · 2021
    Randomized trial110 participantsAnti-Inflammatory Support forVitamin E
  12. Effect of vitamin E supplementation on serum C-reactive protein level: a meta-analysis of randomized controlled trials.
    Saboori S; Shab-Bidar S; Speakman JR; Yousefi Rad E; Djafarian K · European journal of clinical nutrition · 2016
    Meta-analysis495 participants12 studies pooledAnti-Inflammatory Support forVitamin E
  13. Efficacy of Nutritional Interventions on Inflammatory Markers in Haemodialysis Patients: A Systematic Review and Limited Meta-Analysis.
    Khor BH; Narayanan SS; Sahathevan S; Gafor AHA; Daud ZAM; Khosla P; Sabatino A; Fiaccadori E; Chinna K; Karupaiah T · Nutrients · 2018
    Meta-analysis46 studies pooledAnti-Inflammatory Support forVitamin E
  14. Vitamin E improves serum markers and histology in adults with metabolic dysfunction-associated steatotic liver disease: Systematic review and meta-analysis.
    Chee NM; Sinnanaidu RP; Chan WK · Journal of gastroenterology and hepatology · 2024
    Meta-analysis8 studies pooledAnti-Inflammatory Support forVitamin E
  15. Delta-tocotrienol supplementation improves biochemical markers of hepatocellular injury and steatosis in patients with nonalcoholic fatty liver disease: A randomized, placebo-controlled trial.
    Pervez MA; Khan DA; Slehria AUR; Ijaz A · Complementary therapies in medicine · 2021
    Randomized trial71 participantsAnti-Inflammatory Support forVitamin E
  16. Real world effectiveness of Hawthorn special extract WS 1442 in a retrospective cohort study from Germany.
    Wyss C; Gündling PW; Kostev K · Scientific reports · 2024
    Cohort study9,100 participantsCardiovascular Support forHawthorn
  17. Hawthorn (Crataegus spp.) Clinically Significantly Reduces Blood Pressure in Hypertension: A Meta-Analysis of Randomized Placebo-Controlled Clinical Trials.
    Szikora Z; Mátyus RO; Szabó BV; Csupor D; Tóth B · Pharmaceuticals (Basel, Switzerland) · 2025
    Meta-analysis428 participants6 studies pooledCardiovascular Support forHawthorn
  18. A randomised double blind placebo controlled clinical trial of a standardised extract of fresh Crataegus berries (Crataegisan) in the treatment of patients with congestive heart failure NYHA II.
    Degenring FH; Suter A; Weber M; Saller R · Phytomedicine : international journal of phytotherapy and phytopharmacology · 2003
    Randomized trial143 participantsCardiovascular Support forHawthorn
  19. [Crataegus Special Extract WS 1442. Assessment of objective effectiveness in patients with heart failure (NYHA II)].
    Weikl A; Assmus KD; Neukum-Schmidt A; Schmitz J; Zapfe G; Noh HS; Siegrist J · Fortschritte der Medizin · 1996
    Randomized trial136 participantsCardiovascular Support forHawthorn
  20. Prospective, comparative cohort studies and their contribution to the benefit assessments of therapeutic options: heart failure treatment with and without Hawthorn special extract WS 1442.
    Habs M · Forschende Komplementarmedizin und klassische Naturheilkunde = Research in complementary and natural classical medicine · 2005
    Cohort study952 participantsCardiovascular Support forHawthorn
  21. Effects of long-term vitamin E supplementation on cardiovascular events and cancer: a randomized controlled trial.
    Lonn E; Bosch J; Yusuf S; Sheridan P; Pogue J; Arnold JM; Ross C; Arnold A; Sleight P; Probstfield J; Dagenais GR; HOPE and HOPE-TOO Trial Investigators · JAMA · 2005
    Randomized trial9,541 participantsCardiovascular Support forVitamin E
  22. Independent and combined associations of dietary antioxidant exposure with all-cause and cause-specific mortality in the general population.
    Liu Z; He Z; Xing Y · Journal of nutritional science · 2026
    Cohort study34,955 participantsCardiovascular Support forVitamin E
  23. Tocotrienol rich fraction supplementation improved lipid profile and oxidative status in healthy older adults: A randomized controlled study.
    Chin SF; Ibahim J; Makpol S; Abdul Hamid NA; Abdul Latiff A; Zakaria Z; Mazlan M; Mohd Yusof YA; Abdul Karim A; Wan Ngah WZ · Nutrition & metabolism · 2011
    Randomized trial62 participantsCardiovascular Support forVitamin E