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Kyolic AC E & Herbal Antioxidants

Kyolic
4.7
★ ★ ★ ★ ★
(839 ratings)
Vitamin A 2500 IU
Vitamin E 15 IU
Gluthathione 25 mg
Milk Thistle 50 mg
Green Tea 75 mg
Product Image
Score77
An affordable aged-garlic antioxidant blend with good breadth, but most specialty ingredients are too modest for focused use.
How scoring works
Quantity:200 Capsule(s) • (100 servings)
Goals:
Skin Health
Vision Support

Score 77

An affordable aged-garlic antioxidant blend with good breadth, but most specialty ingredients are too modest for focused use.
How scoring works
$26.89($0.26 per serving)
iHerb
$ 27.07
Vitacost
$ 27.07
Amazon
$ 26.89
Report prices

Analysis

Aged garlic extract is the central ingredient, supported by beta-carotene, natural vitamin E, selenium, green tea, milk thistle, glutathione, and proanthocyanidins. The serving is inexpensive and the label names many individual amounts.

Green tea powder does not state catechin content, milk thistle is modest, and oral glutathione is only 25 mg. Pine bark and grape seed extracts are also present in small amounts, so the long list overstates the practical depth.

The combination may suit someone seeking broad everyday antioxidant coverage rather than a targeted formula. Users focused on eye or skin support should note that key specialty nutrients and stronger targeted doses are missing.

Who is it for
  • Adults wanting inexpensive broad antioxidant coverage
  • Users interested in aged garlic with vitamins
  • People who prefer a low-cost daily formula
Best for
  • General antioxidant support
  • Aged garlic supplementation
  • Basic vitamin and selenium coverage

Pros

  • Low cost per serving
  • Provides 400 mg aged garlic extract
  • Uses natural-form vitamin E
  • Includes selenium as selenomethionine

Cons

  • Green tea catechin content is not stated
  • Glutathione amount is very low
  • Milk thistle and CoQ10 are absent or not central
  • Lacks key targeted eye nutrients

Warnings

  • Aged garlic may add to bleeding risk with anticoagulant or antiplatelet medicines
  • Beta-carotene supplements may be unsuitable for current or former smokers
  • Green tea powder may contain an unspecified amount of caffeine

Nutrient quality

77 High impact

Good nutrient forms and aged garlic provide a sound antioxidant base. Small doses of glutathione and several plant extracts limit the strength of the broader blend.

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Ingredient transparency

78 High impact

The main active amounts are generally available and no broad proprietary blend obscures the formula. Complete usage directions and non-active ingredients are not supplied, while any noted duplicate or vague entries reduce clarity.

.

Customer satisfaction

70 High impact

Aggregate satisfaction is very strong and supported by a large evidence base. No firsthand experience details are supplied, so recurring complaints and purpose alignment remain uncertain.

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Value for money

85 Highest impact

The long supply and solid ingredient forms create strong practical value. Several small botanical doses are a limitation, but the core antioxidant formula remains competitive.

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Report analysis

Goals

Skin Health
Skin Health
Impact
Moderate effect
C- Goal FitC Strength of SupportC- CoverageB Formula Quality
Vitamin C · 30 mgGluthathione · 25 mgSelenium · 35 mcgGreen Tea · 75 mgVitamin E · 15 IU

Vitamin C, vitamin E, selenium, garlic, green tea, and polyphenol extracts provide antioxidant support relevant to photo-protection. Aged garlic is the dominant disclosed botanical.

Pine bark, grape seed, and glutathione amounts are small, while the formula lacks collagen or barrier-hydration actives. The antioxidant theme is coherent but more general than skin-specific.

Study evidence
Gluthathione Supportive 13 studies
Green Tea Supportive 37 studies
Selenium Supportive 22 studies
Vitamin C Supportive 53 studies
Vitamin E Supportive 38 studies
Vision Support
Vision Support
Impact
Moderate effect
C Goal FitC- Strength of SupportD+ CoverageC- Formula Quality
Vitamin E · 15 IUVitamin C · 30 mgVitamin A · 2500 IU

Beta-carotene, natural vitamin E, selenium, and plant antioxidants provide general oxidative defense relevant to the eye. The formula lacks the core lutein, zeaxanthin, zinc, and DHA combination expected from a focused vision product.

Vitamin A is useful, while vitamin E, selenium, pine bark, and grape seed amounts are modest. Ocular benefits are therefore likely to be limited to general antioxidant nutrition.

Study evidence
Selenium Supportive 15 studies
Vitamin A Supportive 65 studies
Vitamin E Disputed 35 studies

Ingredients

IngredientAmount per serving
Vitamin A (Beta-Carotene)
 2500 IU
Vitamin C (Calcium Ascorbate)
 30 mg
Vitamin E (D-Alpha-Tocopheryl Succinate)
 15 IU
Selenium (L-Selenomethionine)
 35 mcg
Aged Garlic extract powder
400 mg
Green Tea powder
75 mg
Milk Thistle extract (Silymarin)
 50 mg
L-Glutathione
25 mg
Pine bark extract (Proanthocyanidins)
 7.5 mg
Grape seed extract (Proanthocyanidins)
 7.5 mg
Gluten Free Adults 18–50 Dairy Free Sugar Free
Report overview
Vitamin A (Beta-Carotene) · 2500 IU OverallScore70
D+ Active Ingredient Quality & BioavailabilityA+ Dose, Safety & Label TransparencyD+ Value

Beta-carotene supplies provitamin A, but the source and a broader carotenoid profile are not identified. The amount is well aligned with routine use, while the capsule has no stated lipid carrier. Cost efficiency is moderate.

View ingredientView products
Vitamin E (D-Alpha-Tocopheryl Succinate) · 15 IU OverallScore55
D Active Ingredient Quality & BioavailabilityD- Dose, Safety & Label TransparencyA+ Value

Natural d-alpha-tocopheryl succinate provides good form quality. The amount is below the maintenance range, and the formula lacks mixed tocopherols and tocotrienols. The low serving cost supports value despite the modest dose.

View ingredientView products
Gluthathione · 25 mg OverallScore24
F Active Ingredient Quality & BioavailabilityF Dose, Safety & Label TransparencyD- Value

Direct L-glutathione is included, but the label does not confirm a reduced or enhanced-delivery form. The disclosed amount is too small for the potency targets and no branded purity source is identified. Low serving cost helps, yet the small active amount limits practical value.

View ingredientView products
Loading alternative details
68 Performance

Twice Daily Multi

Designs for Health
<p>Mixed carotenoids, natural vitamin E, mixed tocopherols, methylcobalamin, and chelated trace minerals improve form quality and support skin-focused nutrition. High pyridoxine and repeated nutrient entries limit balance, while the formula is less focused on garlic and botanical antioxidants.</p>
66 Performance

Only One Liquid-Gel Multi

Irwin Naturals
<p>Natural vitamin E, beta-carotene, vitamin C, vitamin D3, and selenium give broader nutrient support for skin and vision. Mixed mineral forms, unnecessary iron for some adults, and an unquantified fish-oil contribution are meaningful trade-offs.</p>
68 Performance

Extra Care Liver Support

Renew Life
<p>Milk thistle, green tea, glutathione, selenium, vitamin C, and alpha-lipoic acid provide a more concentrated antioxidant and liver-support blend. Several active yields are unclear and the serving value is weaker, so it is most relevant when detoxification support is the priority.</p>
71 Budget

Norwegian Cod Liver Oil 1000 mg Fresh Orange Flavor

AN Amazing Nutrition Amazing Omega
<p>Cod liver oil supplies natural vitamin E, vitamin D3, and preformed vitamin A at especially economical serving value. The missing DHA and EPA amounts reduce transparency, and the preformed vitamin A calls for care with other vitamin A sources.</p>
72 Budget

Flintstones Gummies + Immunity Support

Bayer
<p>Vitamin A and vitamin E come with useful vitamin C, vitamin D, and zinc at lower serving cost. It is a children's gummy with mostly unspecified nutrient forms, so it is suitable only when the intended user is a child.</p>
59 Budget

Daily Total One

Country Life
<p>Natural vitamin E, beta-carotene, methylcobalamin, and active B-vitamin forms provide broad nutrient coverage at lower serving cost. Repeated label entries and potentially high combined amounts make the formula harder to interpret than the original.</p>
69 Value

Norwegian Cod Liver Oil 1250 mg Fresh Orange Flavor

AN Amazing Nutrition Amazing Omega
<p>A concentrated cod liver oil base provides natural vitamin E, vitamin D3, and preformed vitamin A with strong serving economics. DHA and EPA are not quantified, and users should account for vitamin A from other supplements or foods.</p>
73 Value

Flintstones Gummies + Immunity Support

Bayer
<p>Vitamin A and vitamin E are paired with practical vitamin C, vitamin D, and zinc amounts at low serving cost. The children's format and unspecified nutrient forms make it a value option only for an age-appropriate user, not a direct adult substitute.</p>
70 Value

Poly-Vi-Sol

Enfamil
<p>A compact vitamin A, C, D, E, and B-vitamin panel offers reasonable value for infant supplementation. Every nutrient form is unspecified, so it should be considered only for an infant under age-appropriate guidance rather than as an adult antioxidant formula.</p>
Report alternatives

Sources

Published studies used for the product analysis and the top-ranked studies for each ingredient and goal.

  1. The effects of the oral supplementation of L-Cystine associated with reduced L-Glutathione-GSH on human skin pigmentation: a randomized, double-blinded, benchmark- and placebo-controlled clinical trial.
    Duperray J; Sergheraert R; Chalothorn K; Tachalerdmanee P; Perin F · Journal of cosmetic dermatology · 2022
    Randomized trial124 participantsSkin Health forGluthathione
  2. Skin-whitening and skin-condition-improving effects of topical oxidized glutathione: a double-blind and placebo-controlled clinical trial in healthy women.
    Watanabe F; Hashizume E; Chan GP; Kamimura A · Clinical, cosmetic and investigational dermatology · 2014
    Randomized trial30 participantsSkin Health forGluthathione
  3. Systematic Review of the Efficacy and Safety of Topical Glutathione in Dermatology.
    Khanna R; Rambhia P; Chapas A · The Journal of clinical and aesthetic dermatology · 2025
    Systematic review5 studies pooledSkin Health forGluthathione
  4. Effects of antioxidants on glutathione levels and clinical recovery from the malnutrition syndrome kwashiorkor--a pilot study.
    Becker K; Pons-Kühnemann J; Fechner A; Funk M; Gromer S; Gross HJ; Grünert A; Schirmer RH · Redox report : communications in free radical research · 2006
    Randomized trialSkin Health forGluthathione
  5. Glutathione and its antiaging and antimelanogenic effects.
    Weschawalit S; Thongthip S; Phutrakool P; Asawanonda P · Clinical, cosmetic and investigational dermatology · 2020
    Randomized trial57 participantsSkin Health forGluthathione
  6. Topical Polyphenon E in the treatment of external genital and perianal warts: a randomized controlled trial.
    Stockfleth E; Beti H; Orasan R; Grigorian F; Mescheder A; Tawfik H; Thielert C · The British journal of dermatology · 2008
    Randomized trial503 participantsSkin Health forGreen Tea
  7. Efficacy, safety and tolerability of green tea catechins in the treatment of external anogenital warts: a systematic review and meta-analysis.
    Tzellos TG; Sardeli C; Lallas A; Papazisis G; Chourdakis M; Kouvelas D · Journal of the European Academy of Dermatology and Venereology : JEADV · 2011
    Meta-analysis1,247 participants3 studies pooledSkin Health forGreen Tea
  8. Green Tea Catechin Association with Ultraviolet Radiation-Induced Erythema: A Systematic Review and Meta-Analysis.
    Kapoor MP; Sugita M; Fukuzawa Y; Timm D; Ozeki M; Okubo T · Molecules (Basel, Switzerland) · 2021
    Meta-analysis100 participants6 studies pooledSkin Health forGreen Tea
  9. Green tea polyphenols provide photoprotection, increase microcirculation, and modulate skin properties of women.
    Heinrich U; Moore CE; De Spirt S; Tronnier H; Stahl W · The Journal of nutrition · 2011
    Randomized trial60 participantsSkin Health forGreen Tea
  10. Efficacy of Epigallocatechin-3-Gallate in Preventing Dermatitis in Patients With Breast Cancer Receiving Postoperative Radiotherapy: A Double-Blind, Placebo-Controlled, Phase 2 Randomized Clinical Trial.
    Zhao H; Zhu W; Zhao X; Li X; Zhou Z; Zheng M; Meng X; Kong L; Zhang S; He D; Xing L; Yu J · JAMA dermatology · 2022
    Randomized trial180 participantsSkin Health forGreen Tea
  11. Comparative clinical trial of bifonazole solution versus selenium sulphide shampoo in the treatment of pityriasis versicolor.
    Chu AC · Dermatologica · 1985
    Randomized trial38 participantsSkin Health forSelenium
  12. Selenium supplementation and secondary prevention of nonmelanoma skin cancer in a randomized trial.
    Duffield-Lillico AJ; Slate EH; Reid ME; Turnbull BW; Wilkins PA; Combs GF; Park HK; Gross EG; Graham GF; Stratton MS; Marshall JR; Clark LC; Nutritional Prevention of Cancer Study Group · Journal of the National Cancer Institute · 2003
    Randomized trial1,312 participantsSkin Health forSelenium
  13. Evidence-Based Nutritional Interventions in Wound Care.
    Saeg F; Orazi R; Bowers GM; Janis JE · Plastic and reconstructive surgery · 2021
    Systematic review2,339 participants36 studies pooledSkin Health forSelenium Skin Health forVitamin E
  14. A randomized, double-blind placebo-controlled trial evaluating the effects of vitamin E and selenium on arsenic-induced skin lesions in Bangladesh.
    Verret WJ; Chen Y; Ahmed A; Islam T; Parvez F; Kibriya MG; Graziano JH; Ahsan H · Journal of occupational and environmental medicine · 2006
    Randomized trial121 participantsSkin Health forSelenium
  15. The Whitening, Moisturizing, Anti-aging Activities, and Skincare Evaluation of Selenium-Enriched Mung Bean Fermentation Broth.
    Wei K; Guo C; Zhu J; Wei Y; Wu M; Huang X; Zhang M; Li J; Wang X; Wang Y; Wei X · Frontiers in nutrition · 2022
    Clinical trial31 participantsSkin Health forSelenium
  16. Evaluation of the anti-wrinkle effect of an ascorbic acid-loaded dissolving microneedle patch via a double-blind, placebo-controlled clinical study.
    Lee C; Yang H; Kim S; Kim M; Kang H; Kim N; An S; Koh J; Jung H · International journal of cosmetic science · 2017
    Randomized trial23 participantsSkin Health forVitamin C
  17. Comparative Study on the Outcome of Periorbital Wrinkles Treated with Laser-Assisted Delivery of Vitamin C or Vitamin C Plus Growth Factors: A Randomized, Double-blind, Clinical Trial.
    Machado BHB; Frame J; Zhang J; Najlah M · Aesthetic plastic surgery · 2021
    Randomized trial149 participantsSkin Health forVitamin C
  18. Randomized trial of topical ascorbic acid in DMSO versus imiquimod for the treatment of basal cell carcinoma.
    Burke B; Bailie JE · Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie · 2022
    Randomized trial25 participantsSkin Health forVitamin C
  19. Vitamin C improves healing of foot ulcers: a randomised, double-blind, placebo-controlled trial.
    Gunton JE; Girgis CM; Lau T; Vicaretti M; Begg L; Flood V · The British journal of nutrition · 2022
    Randomized trial16 participantsSkin Health forVitamin C
  20. Dietary nutrient intakes and skin-aging appearance among middle-aged American women.
    Cosgrove MC; Franco OH; Granger SP; Murray PG; Mayes AE · The American journal of clinical nutrition · 2007
    Cross-sectional study4,025 participantsSkin Health forVitamin C
  21. Randomized controlled trial using vitamins E and D supplementation in atopic dermatitis.
    Javanbakht MH; Keshavarz SA; Djalali M; Siassi F; Eshraghian MR; Firooz A; Seirafi H; Ehsani AH; Chamari M; Mirshafiey A · The Journal of dermatological treatment · 2011
    Randomized trial45 participantsSkin Health forVitamin E
  22. Serum vitamin E levels and chronic inflammatory skin diseases: A systematic review and meta-analysis.
    Liu X; Yang G; Luo M; Lan Q; Shi X; Deng H; Wang N; Xu X; Zhang C · PloS one · 2022
    Meta-analysis20 studies pooledSkin Health forVitamin E
  23. Effects of tocotrienol on aging skin: A systematic review.
    Ghazali NI; Mohd Rais RZ; Makpol S; Chin KY; Yap WN; Goon JA · Frontiers in pharmacology · 2022
    Systematic reviewSkin Health forVitamin E
  24. Carotenoids and carotenoids plus vitamin E protect against ultraviolet light-induced erythema in humans.
    Stahl W; Heinrich U; Jungmann H; Sies H; Tronnier H · The American journal of clinical nutrition · 2000
    Randomized trialSkin Health forVitamin E
  25. Efficacy and safety of AZR-MD-001 selenium sulfide ophthalmic ointment in adults with meibomian gland dysfunction: A vehicle-controlled, randomized clinical trial.
    Watson SL; Jones LW; Stapleton F; Hinds M; Ng A; Tan J; Alster Y; Bosworth C; Rafaeli O; DePuy V; CELESTIAL STUDY Group · The ocular surface · 2026
    Randomized trial245 participantsVision Support forSelenium
  26. The efficacy and safety of selenium supplementation versus placebo in the treatment of Graves' orbitopathy: A systematic review and meta-analysis of randomised controlled trials.
    Sharabati I; Qafesha RM; Hindawi MD; Amro S; Ayesh BM · Clinical endocrinology · 2024
    Meta-analysis4 studies pooledVision Support forSelenium
  27. Efficacy and safety of AZR-MD-001 selenium sulfide ophthalmic ointment in adults with meibomian gland dysfunction over six months of treatment: A Phase 2, vehicle-controlled, randomized extension trial.
    Downie LE; Craig JP; Stapleton F; Tan J; Jones LW; Ng A; Hinds M; Bosworth C; Alster Y · The ocular surface · 2025
    Randomized trial245 participantsVision Support forSelenium
  28. AZR-MD-001 0.5% selenium sulfide ophthalmic ointment for the treatment of contact lens discomfort: A vehicle-controlled, randomized, clinical trial.
    Stapleton F; Hinds M; Tan J; Jones L; Chalmers R; Bosworth C; Alster Y · The ocular surface · 2025
    Randomized trial67 participantsVision Support forSelenium
  29. The effect of a biweekly novel selenium sulfide-containing topical treatment in symptomatic contact lens wearers: An exploratory study.
    Stapleton F; Jia T; DePuy V; Bosworth C; Gleeson M; Tan J · The ocular surface · 2025
    Randomized trial14 participantsVision Support forSelenium
  30. A randomized trial of vitamin A and vitamin E supplementation for retinitis pigmentosa.
    Berson EL; Rosner B; Sandberg MA; Hayes KC; Nicholson BW; Weigel-DiFranco C; Willett W · Archives of ophthalmology (Chicago, Ill. : 1960) · 1993
    Randomized trial601 participantsVision Support forVitamin A
  31. Efficacy and safety of retinol palmitate ophthalmic solution in the treatment of dry eye: a Japanese Phase II clinical trial.
    Toshida H; Funaki T; Ono K; Tabuchi N; Watanabe S; Seki T; Otake H; Kato T; Ebihara N; Murakami A · Drug design, development and therapy · 2018
    Randomized trial66 participantsVision Support forVitamin A
  32. Vitamin A supplementation for preventing morbidity and mortality in children from six months to five years of age.
    Imdad A; Mayo-Wilson E; Haykal MR; Regan A; Sidhu J; Smith A; Bhutta ZA · The Cochrane database of systematic reviews · 2022
    Meta-analysis1,223,856 participants47 studies pooledVision Support forVitamin A
  33. Vitamin A supplementation improves retinal function in infants at risk of retinopathy of prematurity.
    Mactier H; McCulloch DL; Hamilton R; Galloway P; Bradnam MS; Young D; Lavy T; Farrell L; Weaver LT · The Journal of pediatrics · 2012
    Randomized trial89 participantsVision Support forVitamin A
  34. Effect of short-term, high-dose retinol on dark adaptation in aging and early age-related maculopathy.
    Owsley C; McGwin G; Jackson GR; Heimburger DC; Piyathilake CJ; Klein R; White MF; Kallies K · Investigative ophthalmology & visual science · 2006
    Randomized trial104 participantsVision Support forVitamin A
  35. Antioxidant vitamin and mineral supplements for preventing age-related macular degeneration.
    Evans JR; Lawrenson JG · The Cochrane database of systematic reviews · 2018
    Meta-analysis55,614 participants4 studies pooledVision Support forVitamin E
  36. Dietary n-3 Fatty Acid, α-Tocopherol, Zinc, vitamin D, vitamin C, and β-carotene are Associated with Age-Related Macular Degeneration in Japan.
    Aoki A; Inoue M; Nguyen E; Obata R; Kadonosono K; Shinkai S; Hashimoto H; Sasaki S; Yanagi Y · Scientific reports · 2017
    Case-control study530 participantsVision Support forVitamin E
  37. Dietary carotenoids, vitamins C and E, and risk of cataract in women: a prospective study.
    Christen WG; Liu S; Glynn RJ; Gaziano JM; Buring JE · Archives of ophthalmology (Chicago, Ill. : 1960) · 2008
    Cohort study35,551 participantsVision Support forVitamin E
  38. Long-term nutrient intake and 5-year change in nuclear lens opacities.
    Jacques PF; Taylor A; Moeller S; Hankinson SE; Rogers G; Tung W; Ludovico J; Willett WC; Chylack LT · Archives of ophthalmology (Chicago, Ill. : 1960) · 2005
    Cohort study408 participantsVision Support forVitamin E
  39. Dietary intake of antioxidants and risk of age-related macular degeneration.
    van Leeuwen R; Boekhoorn S; Vingerling JR; Witteman JC; Klaver CC; Hofman A; de Jong PT · JAMA · 2005
    Cohort study4,765 participantsVision Support forVitamin E