St. John's Wort 450 mg

St. John's Wort 450 mg

Solaray4.6 (436 ratings)
Format:Capsule Quantity: 100 VegCap(s) · 50 servings
Goals
$19.99 $0.39 per serving
VitacostLowest$19.99iHerb$19.99Amazon$19.99Walmart$21.59

Product analysis

46 out of 100

St. John's Wort 450 mg is aimed at mood support, though everyday mood benefits from this unspecified preparation remain uncertain. It can weaken oral contraceptives, blood thinners and many other medicines, which materially affects suitability.

AI assessment of the formula, label and price. How scoring works

Nutrient Quality20

The quality of St. John's wort remains uncertain because the preparation is unspecified. Its botanical name alone does not establish a match to a defined extract.

Ingredient Transparency63

The botanical amount is disclosed, allowing comparison of serving sizes. The preparation is unspecified, limiting comparison with defined extracts.

Value For Money40

Value for money remains uncertain for St. John's wort. The available information does not support a cost advantage over alternatives.

Customer Satisfaction74

Customer ratings are favorable across several hundred reviews. That gives useful satisfaction feedback without establishing mood benefits or medicine compatibility.

Product Focus57

A single botanical keeps the formula focused on mood support, but benefits from defined extracts cannot be assumed for this preparation. Interactions with many medicines are a major limitation on suitability.

Format
Capsule
Container
100 VegCap(s)
Per serving
$0.39
Customer rating
4.6 · 436 ratings
Report analysis

Goals

Mood Support
Mood Support
Impact
Moderate effect
A+ Ingredient FitF PathwaysF EvidenceA+ Formulation Logic

St. John's wort has a clearer connection to diagnosed depression than to improving everyday mood in generally healthy adults. The declared botanical material doesn't identify one of the defined extracts, so their effects can't simply be transferred to it. It can also weaken oral contraceptives, anticoagulants and many other medicines, which materially affects whether it is suitable.

How this product is rated for Mood Support

Ingredient fit100

St. John's wort has a more specific role in diagnosed depression than in everyday mood.
Goal fit
St. John's Wort is present; their relevance depends on the specific mood-related role described.
Dose adequacy
St. John's Wort: 900 mg per serving. These are serving amounts, not assumed daily exposure.

Pathways16

The connection is concentrated in one type of mood-related activity, rather than several distinct benefits.
Depth
St. John's wort has a more specific role in diagnosed depression than in everyday mood.
Breadth
The connection is concentrated in one type of mood-related activity, rather than several distinct benefits.

Evidence27

St. John's Wort does not identify the preparation needed to transfer the specific benefit confidently.
Evidence strength
St. John's wort has a more specific role in diagnosed depression than in everyday mood.
Studied preparation
St. John's Wort does not identify the preparation needed to transfer the specific benefit confidently.

Formulation logic100

The ingredients do not require additional partners for their individual roles. No particular conflict is identified within the combination.
Partner coverage
No additional partner ingredient is required for the relevant ingredients to have their individual roles.
Conflicts
No particular ingredient conflict is identified in this combination.
Effective doses
The relevant ingredients have declared amounts within the comparison range; this does not guarantee an emotional benefit.
Study evidence

Ingredients

IngredientAmount per servingScore
organic St. John's Wort
900 mg 50
Adults 18–50 Vegan Vegetarian
Report overview
St. John's Wort · 900 mg OverallScore50
D+ Composition And Label Disclosure
A serving lists 900 mg of St. John's wort. The evaluation records a general warning, but its wording is not available in the saved facts.
How this ingredient is rated

Composition and Label Disclosure

No separate source or delivery criteria were evaluated.

Composition and Label Disclosure50

A general warning is recorded; the saved facts do not provide its wording or an ingredient-specific warning.
Explicit Label Detail
The evaluation records a general warning, but its wording is not available in the saved facts.

Commercial Price and Usability

No price criterion was evaluated.
View ingredientView products
84 Performance

Feeling Positive St. John's Wort 300 mg

Sundown
Marker standardization supports consistent extract quality, though the daily amount is moderate; its extract quality and goal fit provide a clearer option when the original has incomplete potency or marker detail. Saint John’s wort can weaken oral contraceptives and anticoagulants and can interact seriously with serotonergic antidepressants, so medication use needs clinician or pharmacist review.
83 Performance

St. John's Wort Extract 300 mg

Lake Avenue Nutrition
A hypericin-standardized aerial-parts extract gives useful potency clarity and focused mood support, though one serving may provide only a partial daily dose; its extract quality and goal fit provide a clearer option when the original has incomplete potency or marker detail. Saint John’s wort can weaken oral contraceptives and anticoagulants and can interact seriously with serotonergic antidepressants, so medication use needs clinician or pharmacist review.
83 Performance

Perika St. John's Wort

Nature's Way
The named extract supports consistent quality, though the daily amount is moderate; its extract quality and goal fit provide a clearer option when the original has incomplete potency or marker detail. Saint John’s wort can weaken oral contraceptives and anticoagulants and can interact seriously with serotonergic antidepressants, so medication use needs clinician or pharmacist review.
90 Budget

St. John's Wort Extract

Swanson Superior Herbs
Marker standardization supports consistent extract quality, though the daily amount is moderate; the lower serving cost improves economy when the original has incomplete potency or marker detail. Saint John’s wort can weaken oral contraceptives and anticoagulants and can interact seriously with serotonergic antidepressants, so medication use needs clinician or pharmacist review.
90 Budget

St. John's Wort 300 mg

NOW
Marker standardization supports consistent extract quality, though the daily amount is moderate; the lower serving cost improves economy when the original has incomplete potency or marker detail. Saint John’s wort can weaken oral contraceptives and anticoagulants and can interact seriously with serotonergic antidepressants, so medication use needs clinician or pharmacist review.
89 Budget

St. John's Wort 300 mg

California Gold Nutrition EuroHerbs
A hypericin-standardized extract gives useful potency clarity and focused mood support, though one serving may provide only a partial daily dose; the lower serving cost improves economy when the original has incomplete potency or marker detail. Saint John’s wort can weaken oral contraceptives and anticoagulants and can interact seriously with serotonergic antidepressants, so medication use needs clinician or pharmacist review.
87 Value

St. John's Wort Extract 300 mg

Lake Avenue Nutrition
A hypericin-standardized aerial-parts extract gives useful potency clarity and focused mood support, though one serving may provide only a partial daily dose; the quality-to-cost balance is favorable when the original has incomplete potency or marker detail. Saint John’s wort can weaken oral contraceptives and anticoagulants and can interact seriously with serotonergic antidepressants, so medication use needs clinician or pharmacist review.
86 Value

St. John's Wort 300 mg

Nature's Bounty
Marker standardization supports consistent extract quality, though the daily amount is moderate; the quality-to-cost balance is favorable when the original has incomplete potency or marker detail. Saint John’s wort can weaken oral contraceptives and anticoagulants and can interact seriously with serotonergic antidepressants, so medication use needs clinician or pharmacist review.
83 Value

St. John's Wort

Paradise
Marker standardization supports consistent extract quality, though the daily amount is moderate; the quality-to-cost balance is favorable when the original has incomplete potency or marker detail. Saint John’s wort can weaken oral contraceptives and anticoagulants and can interact seriously with serotonergic antidepressants, so medication use needs clinician or pharmacist review.
Report alternatives

Sources

Published studies used for the product analysis and the top-ranked studies for each ingredient and goal.

  1. St John's wort for major depression.
    Linde K; Berner MM; Kriston L · The Cochrane database of systematic reviews · 2009
    Systematic review5,489 participants29 studies pooledMood Support forSt. John's Wort
  2. Efficacy of St. John's wort extract WS 5570 in major depression: a double-blind, placebo-controlled trial.
    Lecrubier Y; Clerc G; Didi R; Kieser M · The American journal of psychiatry · 2002
    Randomized trial375 participantsMood Support forSt. John's Wort
  3. A systematic review and meta-analysis of Hypericum perforatum in depression: a comprehensive clinical review.
    Whiskey E; Werneke U; Taylor D · International clinical psychopharmacology · 2002
    Meta-analysis22 studies pooledMood Support forSt. John's Wort
  4. Efficacy and tolerability of hypericum extract WS 5572 versus placebo in mildly to moderately depressed patients. A randomized double-blind multicenter clinical trial.
    Kalb R; Trautmann-Sponsel RD; Kieser M · Pharmacopsychiatry · 2001
    Randomized trial72 participantsMood Support forSt. John's Wort
  5. Complementary therapies for clinical depression: an overview of systematic reviews.
    Haller H; Anheyer D; Cramer H; Dobos G · BMJ open · 2020
    Systematic review26 studies pooledMood Support forSt. John's Wort