St. John's Wort

St. John's Wort

Oregon's Wild Harvest4.6 (39 ratings)
Format:Liquid Quantity: 2 Liquid(s) · 59 servings
Goals
$28.76 $0.48 per serving
VitacostLowest$28.76iHerb$28.76

Product analysis

45 out of 100

St. John's Wort is aimed at mood support, but its unspecified preparation leaves everyday mood benefits uncertain. It can reduce the effect of birth control pills, blood thinners and many other medicines.

AI assessment of the formula, label and price. How scoring works

Nutrient Quality20

The herbal preparation is not specified. That limits comparison with clearly identified extracts without showing that the ingredient itself is poor quality.

Ingredient Transparency63

Ingredient amounts are disclosed, which helps with serving comparisons. Unspecified preparations make it harder to compare the actual materials used.

Value For Money40

Value remains uncertain because a usable ingredient price comparison is unavailable. The unspecified preparation also limits like-for-like comparisons.

Customer Satisfaction68

Customer feedback is strongly positive. The relatively small review pool limits how representative that feedback may be.

Product Focus57

The formula is focused on mood, but benefits depend on the particular preparation. Everyday mood improvement in healthy adults remains uncertain, and medicine interactions affect suitability.

Format
Liquid
Container
2 Liquid(s)
Per serving
$0.48
Customer rating
4.6 · 39 ratings
Report analysis

Goals

Mood Support
Mood Support
Impact
Moderate effect
A+ Ingredient FitF PathwaysF EvidenceA+ Formulation Logic

St. John's wort has a role in relieving depressive symptoms in people with mild to moderate depression. Here, the preparation is unspecified, so the amount alone doesn't show that it will act like a defined extract or improve everyday mood in healthy adults. It can weaken oral contraceptives, anticoagulants and many other medicines.

How this product is rated for Mood Support

Ingredient fit100

St. John's wort is relevant to depressive symptoms, with applicability depending on the preparation and person. The serving amounts should be understood in that context.
Goal fit
St. John's wort is relevant to depressive symptoms, with applicability depending on the preparation and person.
Dose adequacy
St. John's Wort: 1000 mg per serving; this comparison doesn't predict an individual mood response.

Pathways16

The ingredients relate to mood-associated nerve signalling; that role alone does not predict symptom improvement. Biological roles alone do not predict the size of a mood benefit.
Depth
The ingredients relate to mood-associated nerve signalling; that role alone does not predict symptom improvement.
Breadth
Different biological roles do not by themselves show broader or greater improvement in everyday mood.

Evidence27

St. John's wort's benefit concerns depressive symptoms rather than a universal mood lift.
Evidence strength
St. John's wort's benefit concerns depressive symptoms rather than a universal mood lift.
Studied preparation
The botanical preparation is not identified as matching a defined preparation with the relevant mood effects.

Formulation logic100

The individual ingredient roles do not require a special partner. No particular conflict is identified within this combination.
Partner coverage
No additional ingredient partner is required for the individual roles described here.
Conflicts
No particular ingredient conflict is identified among these declared ingredients.
Effective doses
The declared serving amounts can be compared individually; they do not guarantee mood improvement.
Study evidence

Ingredients

IngredientAmount per servingScore
fresh organic St. John's Wort
1000 mg 50
Gluten Free Adults 18–50 Dairy Free Women Organic
Report overview
St. John's Wort · 1000 mg OverallScore50
D+ Composition And Label Disclosure
A serving lists 1000 mg of St. John's wort. The evaluation records a general warning, but its wording is not available in the saved facts.
How this ingredient is rated

Composition and Label Disclosure

No separate source or delivery criteria were evaluated.

Composition and Label Disclosure50

A general warning is recorded; the saved facts do not provide its wording or an ingredient-specific warning.
Explicit Label Detail
The evaluation records a general warning, but its wording is not available in the saved facts.

Commercial Price and Usability

No price criterion was evaluated.
View ingredientView products
84 Performance

Feeling Positive St. John's Wort 300 mg

Sundown
Marker standardization supports consistent extract quality, though the daily amount is moderate; its extract quality and goal fit provide a clearer option when the original has a weak, secondary, or opaque Saint John’s wort contribution. Saint John’s wort can weaken oral contraceptives and anticoagulants and can interact seriously with serotonergic antidepressants, so medication use needs clinician or pharmacist review.
83 Performance

St. John's Wort Extract 300 mg

Lake Avenue Nutrition
A hypericin-standardized aerial-parts extract gives useful potency clarity and focused mood support, though one serving may provide only a partial daily dose; its extract quality and goal fit provide a clearer option when the original has a weak, secondary, or opaque Saint John’s wort contribution. Saint John’s wort can weaken oral contraceptives and anticoagulants and can interact seriously with serotonergic antidepressants, so medication use needs clinician or pharmacist review.
83 Performance

Perika St. John's Wort

Nature's Way
The named extract supports consistent quality, though the daily amount is moderate; its extract quality and goal fit provide a clearer option when the original has a weak, secondary, or opaque Saint John’s wort contribution. Saint John’s wort can weaken oral contraceptives and anticoagulants and can interact seriously with serotonergic antidepressants, so medication use needs clinician or pharmacist review.
90 Budget

St. John's Wort Extract

Swanson Superior Herbs
Marker standardization supports consistent extract quality, though the daily amount is moderate; the lower serving cost improves economy when the original has a weak, secondary, or opaque Saint John’s wort contribution. Saint John’s wort can weaken oral contraceptives and anticoagulants and can interact seriously with serotonergic antidepressants, so medication use needs clinician or pharmacist review.
90 Budget

St. John's Wort 300 mg

NOW
Marker standardization supports consistent extract quality, though the daily amount is moderate; the lower serving cost improves economy when the original has a weak, secondary, or opaque Saint John’s wort contribution. Saint John’s wort can weaken oral contraceptives and anticoagulants and can interact seriously with serotonergic antidepressants, so medication use needs clinician or pharmacist review.
89 Budget

St. John's Wort 300 mg

California Gold Nutrition EuroHerbs
A hypericin-standardized extract gives useful potency clarity and focused mood support, though one serving may provide only a partial daily dose; the lower serving cost improves economy when the original has a weak, secondary, or opaque Saint John’s wort contribution. Saint John’s wort can weaken oral contraceptives and anticoagulants and can interact seriously with serotonergic antidepressants, so medication use needs clinician or pharmacist review.
87 Value

St. John's Wort Extract 300 mg

Lake Avenue Nutrition
A hypericin-standardized aerial-parts extract gives useful potency clarity and focused mood support, though one serving may provide only a partial daily dose; the quality-to-cost balance is favorable when the original has a weak, secondary, or opaque Saint John’s wort contribution. Saint John’s wort can weaken oral contraceptives and anticoagulants and can interact seriously with serotonergic antidepressants, so medication use needs clinician or pharmacist review.
86 Value

St. John's Wort 300 mg

Nature's Bounty
Marker standardization supports consistent extract quality, though the daily amount is moderate; the quality-to-cost balance is favorable when the original has a weak, secondary, or opaque Saint John’s wort contribution. Saint John’s wort can weaken oral contraceptives and anticoagulants and can interact seriously with serotonergic antidepressants, so medication use needs clinician or pharmacist review.
83 Value

St. John's Wort

Paradise
Marker standardization supports consistent extract quality, though the daily amount is moderate; the quality-to-cost balance is favorable when the original has a weak, secondary, or opaque Saint John’s wort contribution. Saint John’s wort can weaken oral contraceptives and anticoagulants and can interact seriously with serotonergic antidepressants, so medication use needs clinician or pharmacist review.
Report alternatives

Sources

Published studies used for the product analysis and the top-ranked studies for each ingredient and goal.

  1. St John's wort for major depression.
    Linde K; Berner MM; Kriston L · The Cochrane database of systematic reviews · 2009
    Systematic review5,489 participants29 studies pooledMood Support forSt. John's Wort
  2. Efficacy of St. John's wort extract WS 5570 in major depression: a double-blind, placebo-controlled trial.
    Lecrubier Y; Clerc G; Didi R; Kieser M · The American journal of psychiatry · 2002
    Randomized trial375 participantsMood Support forSt. John's Wort
  3. A systematic review and meta-analysis of Hypericum perforatum in depression: a comprehensive clinical review.
    Whiskey E; Werneke U; Taylor D · International clinical psychopharmacology · 2002
    Meta-analysis22 studies pooledMood Support forSt. John's Wort
  4. Efficacy and tolerability of hypericum extract WS 5572 versus placebo in mildly to moderately depressed patients. A randomized double-blind multicenter clinical trial.
    Kalb R; Trautmann-Sponsel RD; Kieser M · Pharmacopsychiatry · 2001
    Randomized trial72 participantsMood Support forSt. John's Wort
  5. Complementary therapies for clinical depression: an overview of systematic reviews.
    Haller H; Anheyer D; Cramer H; Dobos G · BMJ open · 2020
    Systematic review26 studies pooledMood Support forSt. John's Wort