Isopure Zero Carb Creamy Vanilla

Isopure Zero Carb Creamy Vanilla

The Isopure Company4.5 (30,870 ratings)
Format:Powder Quantity: 4 lb(s) · 66 servings
Goals
$114.97 $1.74 per serving

Product analysis

45 out of 100

Isopure Zero Carb Creamy Vanilla offers a vanilla protein option with magnesium and potassium that support normal mineral balance and heart function. Unspecified nutrient forms make detailed quality comparisons harder.

AI assessment of the formula, label and price. How scoring works

Nutrient Quality20

Nutrient forms are unspecified, leaving their quality and absorption characteristics uncertain. The broad nutrient mix alone does not establish an advantage.

Ingredient Transparency58

Most nutrient amounts are provided, but fat and carbohydrate amounts are omitted. Nutrient forms are also unspecified, limiting detailed comparison.

Value For Money46

Potassium compares favorably on value, while several other mineral comparisons are less attractive. Protein and most vitamin comparisons remain unresolved, so the full value is uncertain.

Customer Satisfaction87

Customer ratings are very positive across tens of thousands of reviews. The large review pool gives a broad picture of satisfaction, without proving health benefits.

Product Focus34

Magnesium and potassium provide the clearest support for normal mineral balance and heart function. The many additional nutrient entries do not establish equally broad practical benefits.

Format
Powder
Container
4 lb(s)
Per serving
$1.74
Customer rating
4.5 · 30,870 ratings
Report analysis

Goals

Impact
Moderate effect
D Ingredient FitD- PathwaysA- EvidenceA+ Formulation Logic
Vitamin K · 20 mcgMagnesium · 100 mgVitamin B12 · 3.3 mcgVitamin B6 · 0.5 mgFolate · 160 mcg DFE
Study evidence
Folate Supportive 116 studies
Magnesium Supportive 158 studies
Niacin Supportive 105 studies
Potassium Supportive 182 studies
Selenium Mixed 89 studies
Vitamin B6 Supportive 44 studies
Vitamin K Mixed 62 studies

Ingredients

IngredientAmount per servingScore
Calories
100 Calorie(s)
Total Fat
0 Gram(s)
Cholesterol
10 mg
Sodium
240 mg 69
Total Carbohydrates
0 Gram(s)
Protein
25 Gram(s)
Calcium
340 mg 42
Potassium
370 mg 55
Vitamin A
380 mcg
Vitamin C
15 mg
Vitamin E
5 mg
Vitamin K
20 mcg
Thiamine
0.3 mg
Riboflavin
0.4 mg
Niacin
5 mg
Vitamin B6
0.5 mg
Folate
160 mcg DFE
Vitamin B12
3.3 mcg
Biotin
75 mcg
Pantothenic Acid
2.5 mg
Phosphorus
280 mg
Iodine
38 mcg
Magnesium
100 mg
Zinc
4.2 mg
Selenium
17 mcg
Copper
0.6 mg
Manganese
0.5 mg
Chromium
30 mcg
Molybdenum
18 mcg
Chloride
360 mg 61
Gluten Free Adults 18–50
Report overview
Sodium · 240 mg OverallScore69
D Active Ingredient Quality & BioavailabilityB Dose, Safety & Label TransparencyA+ Value
Chloride · 360 mg OverallScore61
F Active Ingredient Quality & BioavailabilityB+ Dose, Safety & Label TransparencyB+ Value
Calcium · 340 mg OverallScore42
F Active Ingredient Quality & BioavailabilityD- Dose, Safety & Label TransparencyD+ Value
Report alternatives

Sources

Published studies used for the product analysis and the top-ranked studies for each ingredient and goal.

  1. Folic Acid Therapy Reduces the First Stroke Risk Associated With Hypercholesterolemia Among Hypertensive Patients.
    Qin X; Li J; Spence JD; Zhang Y; Li Y; Wang X; Wang B; Sun N; Chen F; Guo J; Yin D; Sun L; Tang G; He M; Fu J; Cai Y; Shi X; Ye P; Chen H; Zhao S; Chen M; Gao C; Kong X; Hou FF; Huang Y; Huo Y · Stroke · 2017
    Randomized trial20,702 participantsHeart Health forFolate
  2. Periconception Red Blood Cell Folate and Offspring Congenital Heart Disease : Nested Case-Control and Mendelian Randomization Studies.
    Chen H; Zhang Y; Wang D; Chen X; Li M; Huang X; Jiang Y; Dou Y; Wang Y; Ma X; Sheng W; Jia B; Yan W; Huang G; SPCC (Shanghai Preconception Cohort) Group · Annals of internal medicine · 2022
    Case-control study985 participantsHeart Health forFolate
  3. Intake of vitamin B6, folate, and vitamin B12 and risk of coronary heart disease: a systematic review and dose-response meta-analysis of prospective cohort studies.
    Jayedi A; Zargar MS · Critical reviews in food science and nutrition · 2020
    Meta-analysis369,746 participants11 studies pooledHeart Health forFolate Heart Health forVitamin B6
  4. Folate Biomarkers, Folate Intake, and Risk of Death From All Causes, Cardiovascular Disease, and Cancer: A Systematic Review and Dose-Response Meta-Analysis of Prospective Cohort Studies.
    Fallah M; Karim Dehnavi M; Lotfi K; Aminianfar A; Azadbakht L; Esmaillzadeh A · Nutrition reviews · 2025
    Meta-analysis423,304 participants25 studies pooledHeart Health forFolate
  5. The association between folic acid supplementation and congenital heart defects: Systematic review and meta-analysis.
    Wondemagegn AT; Afework M · SAGE open medicine · 2022
    Meta-analysis37 studies pooledHeart Health forFolate
  6. Quantitative Association Between Serum/Dietary Magnesium and Cardiovascular Disease/Coronary Heart Disease Risk: A Dose-Response Meta-analysis of Prospective Cohort Studies.
    Zhao L; Hu M; Yang L; Xu H; Song W; Qian Y; Zhao M · Journal of cardiovascular pharmacology · 2020
    Meta-analysis544,581 participants18 studies pooledHeart Health forMagnesium
  7. Effects of magnesium supplementation on improving hyperglycemia, hypercholesterolemia, and hypertension in type 2 diabetes: A pooled analysis of 24 randomized controlled trials.
    Xu L; Li X; Wang X; Xu M · Frontiers in nutrition · 2023
    Meta-analysis1,325 participants24 studies pooledHeart Health forMagnesium
  8. The effect of lowering blood pressure by magnesium supplementation in diabetic hypertensive adults with low serum magnesium levels: a randomized, double-blind, placebo-controlled clinical trial.
    Guerrero-Romero F; Rodríguez-Morán M · Journal of human hypertension · 2009
    Randomized trial82 participantsHeart Health forMagnesium
  9. Positive effects of magnesium supplementation in metabolic syndrome.
    Kisters S; Kisters K; Werner T; Vormann J; Tokmak F; Westhoff T; Gröber U; Predel HG; Reuter H · International journal of clinical pharmacology and therapeutics · 2024
    Randomized trial54 participantsHeart Health forMagnesium
  10. Comparative Efficacy of Nutraceuticals on Endothelial Function: A Systematic Review and Network Meta-Analysis.
    Norouzzadeh M; Rashedi MH; Mahdavi-Mazdeh G; Kosari A; Shahinfar H · Current atherosclerosis reports · 2026
    Meta-analysisHeart Health forMagnesium
  11. Differential effect of two nicotinic acid preparations on low-density lipoprotein subclass distribution in patients classified as low-density lipoprotein pattern A, B, or I.
    Superko HR; McGovern ME; Raul E; Garrett B · The American journal of cardiology · 2004
    Randomized trial180 participantsHeart Health forNiacin
  12. The ARBITER 6-HALTS Trial (Arterial Biology for the Investigation of the Treatment Effects of Reducing Cholesterol 6-HDL and LDL Treatment Strategies in Atherosclerosis): final results and the impact of medication adherence, dose, and treatment duration.
    Villines TC; Stanek EJ; Devine PJ; Turco M; Miller M; Weissman NJ; Griffen L; Taylor AJ · Journal of the American College of Cardiology · 2010
    Randomized trial315 participantsHeart Health forNiacin
  13. The effects of extended-release niacin on carotid intimal media thickness, endothelial function and inflammatory markers in patients with the metabolic syndrome.
    Thoenes M; Oguchi A; Nagamia S; Vaccari CS; Hammoud R; Umpierrez GE; Khan BV · International journal of clinical practice · 2008
    Randomized trial50 participantsHeart Health forNiacin
  14. Effect of niacin therapy on cardiovascular outcomes in patients with coronary artery disease.
    Duggal JK; Singh M; Attri N; Singh PP; Ahmed N; Pahwa S; Molnar J; Singh S; Khosla S; Arora R · Journal of cardiovascular pharmacology and therapeutics · 2010
    Meta-analysis5,137 participants7 studies pooledHeart Health forNiacin
  15. Effect of niacin on endothelial function: a systematic review and meta-analysis of randomized controlled trials.
    Sahebkar A · Vascular medicine (London, England) · 2014
    Meta-analysis441 participants7 studies pooledHeart Health forNiacin
  16. Potassium intake, stroke, and cardiovascular disease a meta-analysis of prospective studies.
    D'Elia L; Barba G; Cappuccio FP; Strazzullo P · Journal of the American College of Cardiology · 2011
    Meta-analysis247,510 participants11 studies pooledHeart Health forPotassium
  17. Oral potassium supplementation for management of essential hypertension: A meta-analysis of randomized controlled trials.
    Poorolajal J; Zeraati F; Soltanian AR; Sheikh V; Hooshmand E; Maleki A · PloS one · 2017
    Meta-analysis1,213 participants23 studies pooledHeart Health forPotassium
  18. Joint association of urinary sodium and potassium excretion with cardiovascular events and mortality: prospective cohort study.
    O'Donnell M; Mente A; Rangarajan S; McQueen MJ; O'Leary N; Yin L; Liu X; Swaminathan S; Khatib R; Rosengren A; Ferguson J; Smyth A; Lopez-Jaramillo P; Diaz R; Avezum A; Lanas F; Ismail N; Yusoff K; Dans A; Iqbal R; Szuba A; Mohammadifard N; Oguz A; Yusufali AH; Alhabib KF; Kruger IM; Yusuf R; Chifamba J; Yeates K; Dagenais G; Wielgosz A; Lear SA; Teo K; Yusuf S; PURE Investigators · BMJ (Clinical research ed.) · 2019
    Cohort study103,570 participantsHeart Health forPotassium
  19. Effect of Potassium Supplementation on Endothelial Function: A Systematic Review and Meta-Analysis of Intervention Studies.
    D'Elia L; Cappuccio FP; Masulli M; La Fata E; Rendina D; Galletti F · Nutrients · 2023
    Meta-analysis332 participants5 studies pooledHeart Health forPotassium
  20. Effects of potassium supplementation on office, home, and 24-h blood pressure in patients with essential hypertension.
    Kawano Y; Minami J; Takishita S; Omae T · American journal of hypertension · 1999
    Randomized trial55 participantsHeart Health forPotassium