Arginine Citrulline

Arginine Citrulline

Format:Tablet Quantity: 45 Tablet(s) · 15 servings
Goals
$17.51 $1.16 per serving

Product analysis

52 out of 100

Arginine Citrulline combines ingredients related to blood flow and exercise, though practical benefits remain uncertain. The citrulline contribution is expensive for the amount provided.

AI assessment of the formula, label and price. How scoring works

Nutrient Quality31

Arginine is identified as a hydrochloride form, but its quality cannot be compared confidently. Unspecified citrulline and beet preparations leave further uncertainty.

Ingredient Transparency75

Ingredient amounts are stated, but some forms are not identified. That limits a full comparison of ingredient quality.

Value For Money30

Arginine offers middling value for its cost, while citrulline is expensive for the amount provided. The combination therefore offers limited price appeal.

Customer Satisfaction76

Customer feedback is very positive, though the number of ratings is relatively limited. Ratings reflect satisfaction and cannot establish effectiveness or safety.

Product Focus67

The formula centers on ingredients related to blood-vessel function and exercise. Their combination does not establish extra benefit or general daily vitality.

Format
Tablet
Container
45 Tablet(s)
Per serving
$1.16
Customer rating
4.8 · 244 ratings
Report analysis

Goals

Impact
High effect
C Ingredient FitD- PathwaysB EvidenceA+ Formulation Logic
Arginine · 2250 mgCitrulline · 750 mg
Study evidence
Arginine Supportive 47 studies
Citrulline Supportive 33 studies
Impact
High effect
C+ Ingredient FitD- PathwaysC+ EvidenceA+ Formulation Logic
Study evidence
Arginine No effect 7 studies

Ingredients

IngredientAmount per servingScore
L-Arginine (L-Arginine Hydrochloride)
2250 mg 72
L-Citrulline
750 mg 54
Beet
600 mg
Adults 18–50 Women
Report overview
B- Active Ingredient Quality & BioavailabilityA- Dose, Safety & Label TransparencyD+ Value
Each serving provides 2250 mg of arginine, a substantial amount, and its cost per gram is moderate. The ingredient is L-Arginine Hydrochloride.
How this ingredient is rated

Active Ingredient Quality & Bioavailability70

The ingredient is L-Arginine Hydrochloride.
Arginine Form & Sourcing Purity
The label names L-Arginine Hydrochloride.

Dose, Safety & Label Transparency85

A serving provides 2250 mg of arginine, a substantial amount.
Arginine Dose Per Serving
The serving contains 2250 mg of arginine.

Value50

The cost per gram of arginine is moderate.
Price Per Gram of Arginine
The cost per gram of arginine is moderate.
Citrulline · 750 mg OverallScore54
B- Active Ingredient Quality & BioavailabilityC Dose, Safety & Label TransparencyF Value
A serving supplies 750 mg of L-Citrulline at a high product cost relative to its citrulline content. No specific citrulline purity or sourcing details are provided.
How this ingredient is rated

Active Ingredient Quality & Bioavailability70

The listed form is L-Citrulline. No specific citrulline purity or sourcing details are provided.
Citrulline Form Specificity
The listed form is L-Citrulline.
Purity and Sourcing Markers
No specific citrulline purity or sourcing details are provided.

Dose, Safety & Label Transparency64

A serving provides 750 mg of L-Citrulline. The citrulline amount and form are individually listed.
L-Citrulline Dosage Efficacy
A serving provides 750 mg of L-Citrulline.
Label Clarity and Transparency
The citrulline amount and form are individually listed.

Value0

The product cost relative to its citrulline content is high.
Price per Gram of L-Citrulline
The product cost per gram of citrulline is high.
Report alternatives

Sources

Published studies used for the product analysis and the top-ranked studies for each ingredient and goal.

  1. Reassessment of the effect of oral l-arginine on blood pressure: A systematic review and meta-analysis based on ambulatory blood pressure monitoring.
    Shi Y; Liu Y; Zhou Z; Xu S; Luo P · Nitric oxide : biology and chemistry · 2026
    Meta-analysis202 participants5 studies pooledCardiovascular Support forArginine
  2. Effect of Long-Term L-Arginine Supplementation on Arterial Compliance and Metabolic Parameters in Patients with Multiple Cardiovascular risk Factors: Randomized, Placebo-Controlled Study.
    Guttman H; Zimlichman R; Boaz M; Matas Z; Shargorodsky M · Journal of cardiovascular pharmacology · 2024
    Randomized trial90 participantsCardiovascular Support forArginine
  3. Increase in fasting vascular endothelial function after short-term oral L-arginine is effective when baseline flow-mediated dilation is low: a meta-analysis of randomized controlled trials.
    Bai Y; Sun L; Yang T; Sun K; Chen J; Hui R · The American journal of clinical nutrition · 2009
    Meta-analysis492 participants13 studies pooledCardiovascular Support forArginine
  4. L-arginine improves endothelial function and reduces LDL oxidation in patients with stable coronary artery disease.
    Yin WH; Chen JW; Tsai C; Chiang MC; Young MS; Lin SJ · Clinical nutrition (Edinburgh, Scotland) · 2006
    Randomized trial31 participantsCardiovascular Support forArginine
  5. Oral L-Arginine Administration Improves Anthropometric and Biochemical Indices Associated With Cardiovascular Diseases in Obese Patients: A Randomized, Single Blind Placebo Controlled Clinical Trial.
    Dashtabi A; Mazloom Z; Fararouei M; Hejazi N · Research in cardiovascular medicine · 2016
    Randomized trial90 participantsCardiovascular Support forArginine
  6. Does l-citrulline supplementation and watermelon intake reduce blood pressure in middle-aged and older adults? A systematic review and meta-analysis of randomized controlled trials.
    Luo P; Chen J; Liu K; Zhang J · Clinical nutrition ESPEN · 2025
    Meta-analysis415 participants15 studies pooledCardiovascular Support forCitrulline
  7. Micronutrient Supplementation to Reduce Cardiovascular Risk.
    An P; Wan S; Luo Y; Luo J; Zhang X; Zhou S; Xu T; He J; Mechanick JI; Wu WC; Ren F; Liu S · Journal of the American College of Cardiology · 2022
    Meta-analysis883,627 participants884 studies pooledCardiovascular Support forCitrulline
  8. l-Citrulline supplementation improves O2 uptake kinetics and high-intensity exercise performance in humans.
    Bailey SJ; Blackwell JR; Lord T; Vanhatalo A; Winyard PG; Jones AM · Journal of applied physiology (Bethesda, Md. : 1985) · 2016
    Randomized trial10 participantsCardiovascular Support forCitrulline
  9. Effects of L-Citrulline Supplementation on Endothelial Function and Blood Pressure in Hypertensive Postmenopausal Women.
    Maharaj A; Fischer SM; Dillon KN; Kang Y; Martinez MA; Figueroa A · Nutrients · 2022
    Randomized trial25 participantsCardiovascular Support forCitrulline
  10. Short-term effects of L-citrulline supplementation on arterial stiffness in middle-aged men.
    Ochiai M; Hayashi T; Morita M; Ina K; Maeda M; Watanabe F; Morishita K · International journal of cardiology · 2012
    Randomized trial15 participantsCardiovascular Support forCitrulline
  11. Investigation of the effect of nitrate and L-arginine intake on aerobic, anaerobic performance, balance, agility, and recovery in elite taekwondo athletes.
    Kavcı Z; Ozan M; Buzdağlı Y; Savaş A; Uçar H · Journal of the International Society of Sports Nutrition · 2024
    Randomized trial15 participantsEnergy forArginine
  12. The Effects of Arginine-Based Supplements on Fatigue Levels following COVID-19 Infection: A Prospective Study in Romania.
    Turcu-Stiolica A; Ionele CM; Ungureanu BS; Subtirelu MS · Healthcare (Basel, Switzerland) · 2023
    Non-randomized trial505 participantsEnergy forArginine
  13. Isolated but not combined ergogenic effects of caffeine and L-arginine during an isokinetic knee extension.
    Zart S; Brachtendorf M; Becker S; Fröhlich M · Frontiers in nutrition · 2024
    Randomized trial29 participantsEnergy forArginine
  14. L-Arginine but not L-glutamine likely increases exogenous carbohydrate oxidation during endurance exercise.
    Rowlands DS; Clarke J; Green JG; Shi X · European journal of applied physiology · 2012
    Randomized trial8 participantsEnergy forArginine
  15. Effect of L-arginine on energy metabolism, skeletal muscle and brown adipose tissue in South Asian and Europid prediabetic men: a randomised double-blinded crossover study.
    Boon MR; Hanssen MJW; Brans B; Hülsman CJM; Hoeks J; Nahon KJ; Bakker C; van Klinken JB; Havekes B; Schaart G; Jazet IM; Rensen PCN; van Marken Lichtenbelt WD · Diabetologia · 2019
    Randomized trial20 participantsEnergy forArginine
  16. Acute Effect of Citrulline Malate on Repetition Performance During Strength Training: A Systematic Review and Meta-Analysis.
    Vårvik FT; Bjørnsen T; Gonzalez AM · International journal of sport nutrition and exercise metabolism · 2021
    Meta-analysis137 participants8 studies pooledEnergy forCitrulline
  17. Oral L-citrulline supplementation enhances cycling time trial performance in healthy trained men: Double-blind randomized placebo-controlled 2-way crossover study.
    Suzuki T; Morita M; Kobayashi Y; Kamimura A · Journal of the International Society of Sports Nutrition · 2016
    Randomized trial22 participantsEnergy forCitrulline
  18. Citrulline malate enhances athletic anaerobic performance and relieves muscle soreness.
    Pérez-Guisado J; Jakeman PM · Journal of strength and conditioning research · 2010
    Randomized trial41 participantsEnergy forCitrulline
  19. Citrulline/malate promotes aerobic energy production in human exercising muscle.
    Bendahan D; Mattei JP; Ghattas B; Confort-Gouny S; Le Guern ME; Cozzone PJ · British journal of sports medicine · 2002
    Single-arm trial18 participantsEnergy forCitrulline
  20. The Effect of Citrulline Malate Supplementation on Muscle Fatigue Among Healthy Participants.
    Farney TM; Bliss MV; Hearon CM; Salazar DA · Journal of strength and conditioning research · 2019
    Randomized trial12 participantsEnergy forCitrulline