Wellness ImmuNitric

Wellness ImmuNitric

Source Naturals4.6 (27 ratings)
Format:Powder Quantity: 8 Ounce(s) · 30 servings
Goals
$18.54 $0.61 per serving

Product analysis

52 out of 100

Wellness ImmuNitric combines B vitamins with arginine and citrulline for nutritional and blood-flow support. The arginine offers good value, while citrulline is expensive for the amount supplied.

AI assessment of the formula, label and price. How scoring works

Nutrient Quality34

The relative quality of the named vitamin and arginine forms remains uncertain. Citrulline's form is unnamed, limiting a clear comparison of that ingredient.

Ingredient Transparency63

All listed amounts are disclosed, but several ingredient forms are missing. Folate comes from a mixture whose proportions are not given, leaving its full composition unclear.

Value For Money44

Arginine offers good value, while citrulline is expensive for the amount supplied. Uncertain value for the vitamins and other ingredients prevents a clear cost judgment for the complete formula.

Customer Satisfaction68

The available ratings are generally positive, but they come from a small group of customers. That gives only a limited view of satisfaction and does not establish improved energy or circulation.

Product Focus68

The B vitamins support normal nutritional functions, while the amino acids have a separate blood-flow purpose. Evidence for routine vascular and performance benefits is inconsistent, especially for the small citrulline contribution.

Format
Powder
Container
8 Ounce(s)
Per serving
$0.61
Customer rating
4.6 · 27 ratings
Report analysis

Goals

Cardiovascular Support
Impact
High effect
B- Ingredient FitD PathwaysB- EvidenceA+ Formulation Logic
Arginine · 2400 mgVitamin B6 · 7.5 mgFolate · 425 mcg DFECitrulline · 600 mg

Folate and vitamin B6 support homocysteine metabolism, but lowering homocysteine does not automatically reduce cardiovascular events. Declared arginine supplies a nitric-oxide precursor, although routine blood-pressure benefits are not established. Citrulline is present in a small amount. A separate L-arginine entry remains unresolved and cannot be treated as an additional dose.

How this product is rated for Cardiovascular Support

Ingredient fit71

Arginine, folate and B6 contribute to the saved findings.
Goal fit
Arginine, folate and B6 are the main contributors to the goal comparison.
Dose adequacy
The declared amino acids and nutrients contribute at partial amounts; the separate L-arginine entry remains unresolved.

Pathways49

Homocysteine metabolism is prominent; the nitric-oxide contribution is smaller.
Depth
Homocysteine clearance is the strongest recorded area.
Breadth
Homocysteine metabolism is prominent; the nitric-oxide contribution is smaller.

Evidence74

Arginine leads the saved evidence comparison, with clinical context limiting the benefits that can be inferred.
Evidence strength
Arginine leads the saved comparison; this does not establish cardiovascular-event prevention.
Studied preparation
The qualifying preparations meet the saved criteria; this does not establish equal benefit across populations.

Formulation logic100

The qualifying ingredients reach meaningful amounts, with no required missing partner or matched conflict.
Partner coverage
Each qualifying ingredient works alone or has its required partner; this does not establish added benefit from combining them.
Conflicts
No configured ingredient conflict was identified in the supplied facts.
Effective doses
Arginine, folate and B6 provide meaningful amounts under the saved comparison.
Study evidence
Arginine Supportive 47 studies
Citrulline Supportive 33 studies
Folate Supportive 93 studies
Vitamin B6 Supportive 35 studies
Impact
High effect
B+ Ingredient FitD PathwaysC+ EvidenceA+ Formulation Logic

Folate and vitamin B6 support normal nutrient functions and can help address tiredness associated with low intake. Arginine and L-citrulline contribute to the saved blood-flow findings, but arginine's performance evidence is inconsistent and citrulline findings are exercise-specific. The small pure L-citrulline amount should not inherit results from larger citrulline-malate exposures. Nutritional support and exercise effects remain separate expectations.

How this product is rated for Energy

Ingredient fit84

The relevant ingredients provide a focused connection to energy. Their declared amounts only partly meet the saved amount references.
Goal fit
Relevant ingredients dominate the saved energy fit, although links to other goals broaden the product's focus.
Dose adequacy
Several amounts provide partial contributions against the saved references rather than full amount coverage.

Pathways46

The strongest saved connection is blood flow and nitric oxide. Only this pathway reached the breadth threshold.
Depth
The strongest saved connection is blood flow and nitric oxide.
Breadth
Only the strongest pathway meets the saved breadth threshold; the other assessed pathways do not.

Evidence66

Arginine provides the leading evidence contribution in the saved findings. The included preparations met the saved preparation check, which does not establish unconditional fatigue relief.
Evidence strength
Arginine supplies the leading evidence contribution; its specific population and outcome limitations still apply.
Studied preparation
The included ingredients meet the saved preparation check; this does not prove finished-product efficacy.

Formulation logic100

The included ingredients have no missing required partners, and no configured conflict was matched. Each included amount clears the saved minimum comparison threshold.
Partner coverage
No required partner is missing from the included contributions.
Conflicts
No configured ingredient conflict was matched; this is not a comprehensive safety assessment.
Effective doses
All included ingredients clear the saved minimum amount threshold; this is a comparison cutoff, not proof of effective fatigue treatment.
Study evidence
Arginine No effect 7 studies

Ingredients

IngredientAmount per servingScore
Calories
20 Calorie(s)
Total Carbohydrates
1 Gram(s)
Vitamin B6 (Pyridoxine Hydrochloride)
7.5 mg
Folate (Calcium Folinate, Folic Acid)
425 mcg DFE
Sodium
260 mg
L-Arginine (L-Arginine Hydrochloride)
2400 mg 78
L-Citrulline
600 mg 44
Adults 18–50
Report overview
B- Active Ingredient Quality & BioavailabilityA- Dose, Safety & Label TransparencyB+ Value
Each serving supplies 2,400 mg of arginine from L-arginine hydrochloride. The whole-product price works out to about $0.25 per gram of arginine.
How this ingredient is rated

Active Ingredient Quality & Bioavailability70

The identified form is L-arginine hydrochloride.
Arginine Form & Sourcing Purity
L-arginine hydrochloride is the recorded source.

Dose, Safety & Label Transparency85

Each powder serving provides 2,400 mg of arginine.
Arginine Dose Per Serving
The 2,400 mg amount falls in the evaluation’s second-highest amount category.

Value80

The arginine-normalized cost is about $0.25 per gram, based on the whole-product price.
Price Per Gram of Arginine
The whole-product price is approximately $0.25 per gram of arginine.
Citrulline · 600 mg OverallScore44
B- Active Ingredient Quality & BioavailabilityD- Dose, Safety & Label TransparencyF Value
A serving provides 600 mg of L-citrulline, a relatively small amount in this comparison. The whole-product price works out to about $1.01 per gram of L-citrulline.
How this ingredient is rated

Active Ingredient Quality & Bioavailability70

The ingredient is listed as L-citrulline rather than a citrulline malate mixture. No citrulline-specific source, grade, or purity claim is recorded in the saved facts.
Citrulline Form Specificity
The ingredient is listed as L-citrulline rather than a citrulline malate mixture.
Purity and Sourcing Markers
No citrulline-specific source, grade, or purity claim is recorded in the saved facts.

Dose, Safety & Label Transparency40

A serving provides 600 mg of L-citrulline, a relatively small amount in this comparison. The amount is individually listed.
L-Citrulline Dosage Efficacy
A serving provides 600 mg of L-citrulline, a relatively small amount in this comparison.
Label Clarity and Transparency
The individual L-citrulline amount is recorded as 600 mg per serving.

Value0

The whole-product price works out to about $1.01 per gram of L-citrulline.
Price per Gram of L-Citrulline
The whole-product price works out to about $1.01 per gram of L-citrulline.
Report alternatives

Sources

Published studies used for the product analysis and the top-ranked studies for each ingredient and goal.

  1. Reassessment of the effect of oral l-arginine on blood pressure: A systematic review and meta-analysis based on ambulatory blood pressure monitoring.
    Shi Y; Liu Y; Zhou Z; Xu S; Luo P · Nitric oxide : biology and chemistry · 2026
    Meta-analysis202 participants5 studies pooledCardiovascular Support forArginine
  2. Effect of Long-Term L-Arginine Supplementation on Arterial Compliance and Metabolic Parameters in Patients with Multiple Cardiovascular risk Factors: Randomized, Placebo-Controlled Study.
    Guttman H; Zimlichman R; Boaz M; Matas Z; Shargorodsky M · Journal of cardiovascular pharmacology · 2024
    Randomized trial90 participantsCardiovascular Support forArginine
  3. Increase in fasting vascular endothelial function after short-term oral L-arginine is effective when baseline flow-mediated dilation is low: a meta-analysis of randomized controlled trials.
    Bai Y; Sun L; Yang T; Sun K; Chen J; Hui R · The American journal of clinical nutrition · 2009
    Meta-analysis492 participants13 studies pooledCardiovascular Support forArginine
  4. L-arginine improves endothelial function and reduces LDL oxidation in patients with stable coronary artery disease.
    Yin WH; Chen JW; Tsai C; Chiang MC; Young MS; Lin SJ · Clinical nutrition (Edinburgh, Scotland) · 2006
    Randomized trial31 participantsCardiovascular Support forArginine
  5. Oral L-Arginine Administration Improves Anthropometric and Biochemical Indices Associated With Cardiovascular Diseases in Obese Patients: A Randomized, Single Blind Placebo Controlled Clinical Trial.
    Dashtabi A; Mazloom Z; Fararouei M; Hejazi N · Research in cardiovascular medicine · 2016
    Randomized trial90 participantsCardiovascular Support forArginine
  6. Does l-citrulline supplementation and watermelon intake reduce blood pressure in middle-aged and older adults? A systematic review and meta-analysis of randomized controlled trials.
    Luo P; Chen J; Liu K; Zhang J · Clinical nutrition ESPEN · 2025
    Meta-analysis415 participants15 studies pooledCardiovascular Support forCitrulline
  7. Micronutrient Supplementation to Reduce Cardiovascular Risk.
    An P; Wan S; Luo Y; Luo J; Zhang X; Zhou S; Xu T; He J; Mechanick JI; Wu WC; Ren F; Liu S · Journal of the American College of Cardiology · 2022
    Meta-analysis883,627 participants884 studies pooledCardiovascular Support forCitrulline
  8. l-Citrulline supplementation improves O2 uptake kinetics and high-intensity exercise performance in humans.
    Bailey SJ; Blackwell JR; Lord T; Vanhatalo A; Winyard PG; Jones AM · Journal of applied physiology (Bethesda, Md. : 1985) · 2016
    Randomized trial10 participantsCardiovascular Support forCitrulline
  9. Effects of L-Citrulline Supplementation on Endothelial Function and Blood Pressure in Hypertensive Postmenopausal Women.
    Maharaj A; Fischer SM; Dillon KN; Kang Y; Martinez MA; Figueroa A · Nutrients · 2022
    Randomized trial25 participantsCardiovascular Support forCitrulline
  10. Short-term effects of L-citrulline supplementation on arterial stiffness in middle-aged men.
    Ochiai M; Hayashi T; Morita M; Ina K; Maeda M; Watanabe F; Morishita K · International journal of cardiology · 2012
    Randomized trial15 participantsCardiovascular Support forCitrulline
  11. Associations of dietary folate, vitamin B6 and B12 intake with cardiovascular outcomes in 115664 participants: a large UK population-based cohort.
    Zhang B; Dong H; Xu Y; Xu D; Sun H; Han L · European journal of clinical nutrition · 2023
    Cohort study115,664 participantsCardiovascular Support forFolate
  12. Folate, Homocysteine, and Adverse Outcomes After Ischemic Stroke.
    Shi M; Zheng J; Liu Y; Mao X; Wu X; Chu M; Niu H; Sun L; Chang X; He Y; Liu Y; Guo D; Zhang Y; Zhu Z; Zhao J · Journal of the American Heart Association · 2024
    Cohort study3,530 participantsCardiovascular Support forFolate
  13. Effect of folic acid on endothelial function following acute myocardial infarction.
    Moens AL; Claeys MJ; Wuyts FL; Goovaerts I; Van Hertbruggen E; Wendelen LC; Van Hoof VO; Vrints CJ · The American journal of cardiology · 2007
    Randomized trial40 participantsCardiovascular Support forFolate
  14. Folic acid enhances endothelial function and reduces blood pressure in smokers: a randomized controlled trial.
    Mangoni AA; Sherwood RA; Swift CG; Jackson SH · Journal of internal medicine · 2003
    Randomized trial24 participantsCardiovascular Support forFolate
  15. 5-methyltetrahydrofolate, the active form of folic acid, restores endothelial function in familial hypercholesterolemia.
    Verhaar MC; Wever RM; Kastelein JJ; van Dam T; Koomans HA; Rabelink TJ · Circulation · 1998
    Non-randomized trial20 participantsCardiovascular Support forFolate
  16. Association between serum pyridoxal 5'-phosphate levels and all-cause, cardiovascular mortality, and cardiovascular disease in adults: a population-based cohort study.
    Xuan C; Liu RH; Zhao C; Li J; Zhou TT; Tian QW; He GW · Therapeutic advances in chronic disease · 2024
    Cohort studyCardiovascular Support forVitamin B6
  17. Folate and vitamin B6 rapidly normalize endothelial dysfunction in children with type 1 diabetes mellitus.
    MacKenzie KE; Wiltshire EJ; Gent R; Hirte C; Piotto L; Couper JJ · Pediatrics · 2006
    Randomized trial124 participantsCardiovascular Support forVitamin B6
  18. Pyridoxine improves endothelial function in cardiac transplant recipients.
    Miner SE; Cole DE; Evrovski J; Forrest Q; Hutchison S; Holmes K; Ross HJ · The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation · 2001
    Randomized trial31 participantsCardiovascular Support forVitamin B6
  19. Folate and vitamin B6 from diet and supplements in relation to risk of coronary heart disease among women.
    Rimm EB; Willett WC; Hu FB; Sampson L; Colditz GA; Manson JE; Hennekens C; Stampfer MJ · JAMA · 1998
    Cohort study80,082 participantsCardiovascular Support forVitamin B6
  20. Efficacy and safety of pyridoxal 5'-phosphate (MC-1) in high-risk patients undergoing coronary artery bypass graft surgery: the MEND-CABG II randomized clinical trial.
    MEND-CABG II Investigators; Alexander JH; Emery RW; Carrier M; Ellis SJ; Mehta RH; Hasselblad V; Menasche P; Khalil A; Cote R; Bennett-Guerrero E; Mack MJ; Schuler G; Harrington RA; Tardif JC · JAMA · 2008
    Randomized trial3,023 participantsCardiovascular Support forVitamin B6