Femesse

Femesse

Arthur Andrew Medical4.3 (837 ratings)
Format:Capsule Quantity: 240 Capsule(s) · 60 servings
Goals

Product analysis

55 out of 100

Femesse provides nutrients that support normal immune and antioxidant functions when dietary intake is low. Its unnamed blend contents make the contribution of the complete formula difficult to judge.

AI assessment of the formula, label and price. How scoring works

Nutrient Quality55

Natural vitamin E and clearly identified vitamin B6 are the strongest form-related features. Folic acid and selenium offer more limited quality advantages, while zinc and the unnamed blends remain difficult to judge.

Ingredient Transparency71

Serving amounts and most ingredient forms are disclosed. The unnamed blend components leave part of the formula unclear despite those totals.

Value For Money40

Vitamin E and vitamin B6 compare favorably on price. Folate and selenium offer limited value, while the zinc comparison remains uncertain.

Customer Satisfaction71

Customer feedback is positive on average. Hundreds of ratings provide a useful satisfaction picture, without establishing immune benefits.

Product Focus39

The identified nutrients have relevant roles in everyday nutrition and normal immune function. The undisclosed blends make the contribution of the complete mix uncertain.

Format
Capsule
Container
240 Capsule(s)
Per serving
$0.58
Customer rating
4.3 · 837 ratings
Report analysis

Goals

Immunity
Impact
High effect
B Ingredient FitD+ PathwaysA+ EvidenceA+ Formulation Logic
Zinc · 8 mgSelenium · 120 mcg
Study evidence
Selenium Mixed 37 studies
Vitamin E Supportive 21 studies
Zinc Supportive 73 studies
Everyday Health
Impact
Highest effect
B+ Ingredient FitB+ PathwaysB+ EvidenceA+ Formulation Logic
Folate · 100 mcgSelenium · 120 mcgZinc · 8 mg
Study evidence
Folate Supportive 80 studies
Selenium Supportive 70 studies
Zinc Supportive 60 studies

Ingredients

IngredientAmount per servingScore
Vitamin E (D-Alpha-Tocopherol Succinate)
40 IU 59
Vitamin B6 (Pyridoxine Hydrochloride)
40 mg 75
Folate (Folic Acid)
100 mcg 12
Zinc (Zinc Sulfate)
8 mg
Selenium (Selenomethionine)
120 mcg 58
Femesse Proprietary Blend
1940 mg
Proprietary Blend
260 mg
Gluten Free Vegan Dairy Free Women Women 18–50 Vegetarian
Report overview
D+ Active Ingredient Quality & BioavailabilityA- Dose, Safety & Label TransparencyF Value
Each serving provides 120 mcg of selenium, with a high equivalent cost for 200 mcg based on the full serving price. The selenium form is Selenomethionine. The serving is below the stated upper intake limit.
How this ingredient is rated

Active Ingredient Quality & Bioavailability53

The selenium form is Selenomethionine. The label does not specify the L form.
Selenium Chemical Form
The selenium form is Selenomethionine.
Form Transparency & Isomer Specificity
The label does not specify the L form.

Dose, Safety & Label Transparency88

120 mcg per serving provides selenium for daily maintenance. The 120 mcg serving is below the stated upper intake limit.
Dosage Efficacy Sweet Spot
120 mcg per serving provides selenium for daily maintenance.
Safety Margin & UL Adherence
The 120 mcg serving is below the stated upper intake limit.

Value10

The equivalent cost for 200 mcg of selenium is high, based on the full serving price.
Price per 200 mcg Serving
The equivalent cost for 200 mcg of selenium is high, based on the full serving price.
D Active Ingredient Quality & BioavailabilityC+ Dose, Safety & Label TransparencyB- Value
The label lists 40 IU of vitamin E, with a moderate serving price. It names D-Alpha-Tocopheryl Succinate. Individual isomer amounts are not specified.
How this ingredient is rated

Active Ingredient Quality & Bioavailability46

It names D-Alpha-Tocopheryl Succinate. Mixed tocopherols and tocotrienols are not identified.
Natural (d-alpha) vs. Synthetic (dl-alpha)
It names D-Alpha-Tocopheryl Succinate.
Mixed Tocopherol Isomer Diversity
Mixed tocopherols are not identified in the available information.
Tocotrienol Complex Inclusion
Tocotrienols are not identified in the available information.

Dose, Safety & Label Transparency66

The nutrient row declares 40 IU of vitamin E. The form is named, but individual isomer amounts are not specified.
Therapeutic Dosage Range
The nutrient row declares 40 IU of vitamin E.
Label Transparency and Isomer Specificity
The form is named as D-Alpha-Tocopheryl Succinate; individual isomer amounts are not specified.

Value70

The serving price is moderate.
Cost per Natural-Form Therapeutic Serving
The serving price is moderate.
A+ Ingredient Form & Label QualityD Dose, Safety & Label TransparencyB+ Value
The serving provides 40 mg of vitamin B6 at a low cost per milligram, but the amount is high. It uses Pyridoxine Hydrochloride. No dyes, titanium dioxide or talc are listed.
How this ingredient is rated

Ingredient Form & Label Quality100

The B6 comes from Pyridoxine Hydrochloride. No dyes, titanium dioxide or talc are listed.
Vitamin B6 Form Identification
The identified B6 source is Pyridoxine Hydrochloride.
Clean Label and Excipient Purity
No dyes, titanium dioxide or talc are listed.

Dose, Safety & Label Transparency46

The 40 mg per serving is a high amount of vitamin B6. The chemical source is named.
Vitamin B6 Dose & Safety Policy
The 40 mg per serving is a high amount of vitamin B6.
Label Transparency
The label identifies Pyridoxine Hydrochloride as the B6 source.

Value82

The cost per milligram of B6 is low.
Vitamin B6 Price Efficiency
The cost per milligram of B6 is low.
Report alternatives

Sources

Published studies used for the product analysis and the top-ranked studies for each ingredient and goal.

  1. Intakes of Folate, Vitamin B6, and Vitamin B12 in Relation to All-Cause and Cause-Specific Mortality: A National Population-Based Cohort.
    Bo Y; Xu H; Zhang H; Zhang J; Wan Z; Zhao X; Yu Z · Nutrients · 2022
    Cohort study55,569 participantsEveryday Health forFolate
  2. The responsiveness of plasma homocysteine to small increases in dietary folic acid: a primary care study.
    Schorah CJ; Devitt H; Lucock M; Dowell AC · European journal of clinical nutrition · 1998
    Randomized trial119 participantsEveryday Health forFolate
  3. Associations of Serum Folate and Homocysteine Concentrations with All-Cause, Cardiovascular Disease, and Cancer Mortality in Men and Women in Korea: the Cardiovascular Disease Association Study.
    Song S; Song BM; Park HY · The Journal of nutrition · 2023
    Cohort study21,260 participantsEveryday Health forFolate
  4. The concept of folic acid supplementation and its role in prevention of neural tube defect among pregnant women: PRISMA.
    Seyoum Tola F · Medicine · 2024
    Systematic reviewEveryday Health forFolate
  5. Systematic review of adverse health outcomes associated with high serum or red blood cell folate concentrations.
    Colapinto CK; O'Connor DL; Sampson M; Williams B; Tremblay MS · Journal of public health (Oxford, England) · 2017
    Systematic review71,847 participants46 studies pooledEveryday Health forFolate
  6. Associations of selenium status with all-cause and cause-specific mortality: a systematic review and meta-analysis of cohort studies.
    Cui Z; Xie R; Lu X; Schomburg L; Brenner H; Schöttker B · Redox biology · 2025
    Meta-analysis95 participants20 studies pooledEveryday Health forSelenium
  7. Dietary Antioxidants, Circulating Antioxidant Concentrations, Total Antioxidant Capacity, and Risk of All-Cause Mortality: A Systematic Review and Dose-Response Meta-Analysis of Prospective Observational Studies.
    Jayedi A; Rashidy-Pour A; Parohan M; Zargar MS; Shab-Bidar S · Advances in nutrition (Bethesda, Md.) · 2019
    Meta-analysis507,251 participants41 studies pooledEveryday Health forSelenium
  8. The efficacy and safety of selenium supplementation versus placebo in the treatment of Graves' orbitopathy: A systematic review and meta-analysis of randomised controlled trials.
    Sharabati I; Qafesha RM; Hindawi MD; Amro S; Ayesh BM · Clinical endocrinology · 2024
    Meta-analysis4 studies pooledEveryday Health forSelenium
  9. Associations of plasma metal concentrations with the risks of all-cause and cardiovascular disease mortality in Chinese adults.
    Shi L; Yuan Y; Xiao Y; Long P; Li W; Yu Y; Liu Y; Liu K; Wang H; Zhou L; Yang H; Li X; He M; Wu T · Environment international · 2021
    Cohort study6,155 participantsEveryday Health forSelenium
  10. Updates on clinical studies of selenium supplementation in radiotherapy.
    Puspitasari IM; Abdulah R; Yamazaki C; Kameo S; Nakano T; Koyama H · Radiation oncology (London, England) · 2015
    Systematic review16 studies pooledEveryday Health forSelenium
  11. Effectiveness of sodium bicarbonate and zinc chloride mouthwashes in the treatment of oral mucositis and quality of life in patients with cancer under chemotherapy.
    Mohammadi F; Oshvandi K; Kamallan SR; Khazaei S; Ranjbar H; Ahmadi-Motamayel F; Gillespie M; Jenabi E; Vafaei SY · Nursing open · 2022
    Randomized trial144 participantsEveryday Health forZinc
  12. Zinc supplementation in young children with acute diarrhea in India.
    Sazawal S; Black RE; Bhan MK; Bhandari N; Sinha A; Jalla S · The New England journal of medicine · 1995
    Randomized trial937 participantsEveryday Health forZinc
  13. Associations of mortality with ocular disorders and an intervention of high-dose antioxidants and zinc in the Age-Related Eye Disease Study: AREDS Report No. 13.
    Clemons TE; Kurinij N; Sperduto RD; AREDS Research Group · Archives of ophthalmology (Chicago, Ill. : 1960) · 2004
    Randomized trial4,753 participantsEveryday Health forZinc
  14. Effects of zinc and probiotic co-supplementation on inflammation, gastrointestinal symptoms, quality of life, and mood in irritable bowel syndrome patients.
    Rezazadegan M; Soheilipour M; Amani R · Scientific reports · 2026
    Randomized trial84 participantsEveryday Health forZinc
  15. Effect of zinc sulfate supplementation on premenstrual syndrome and health-related quality of life: Clinical randomized controlled trial.
    Siahbazi S; Behboudi-Gandevani S; Moghaddam-Banaem L; Montazeri A · The journal of obstetrics and gynaecology research · 2018
    Randomized trial142 participantsEveryday Health forZinc
  16. Effects of selenium supplementation on selenoprotein gene expression and response to influenza vaccine challenge: a randomised controlled trial.
    Goldson AJ; Fairweather-Tait SJ; Armah CN; Bao Y; Broadley MR; Dainty JR; Furniss C; Hart DJ; Teucher B; Hurst R · PloS one · 2011
    Randomized trial119 participantsImmunity forSelenium
  17. Effect of selenium on immune response against hepatitis B vaccine with accelerated method in insulin-dependent diabetes mellitus patients.
    Janbakhsh A; Mansouri F; Vaziri S; Sayad B; Afsharian M; Rahimi M; Shahebrahimi K; Salari F · Caspian journal of internal medicine · 2013
    Randomized trial62 participantsImmunity forSelenium
  18. Chemoprevention trial of human hepatitis with selenium supplementation in China.
    Yu SY; Li WG; Zhu YJ; Yu WP; Hou C · Biological trace element research · 1990
    Non-randomized trial20,847 participantsImmunity forSelenium
  19. Selenium nanoparticles as adjunctive therapy in sepsis: A pilot randomized clinical trial.
    Gu WJ; Huang W; Zhao FZ; Yuan XK; Jin K; Chen JL; Zhang CY; Huang Y; He L; Zhuang H; Yin HY; Chen T · Drug resistance updates : reviews and commentaries in antimicrobial and anticancer chemotherapy · 2026
    Randomized trial70 participantsImmunity forSelenium
  20. Selenium supplementation in patients with autoimmune thyroiditis decreases thyroid peroxidase antibodies concentrations.
    Gärtner R; Gasnier BC; Dietrich JW; Krebs B; Angstwurm MW · The Journal of clinical endocrinology and metabolism · 2002
    Randomized trial70 participantsImmunity forSelenium