Glycine

Glycine

Pure Encapsulations4.7 (32 ratings)
Format:Capsule Quantity: 180 Capsule(s) · 60 servings
Goals
$35.00 $0.58 per serving

Product analysis

53 out of 100

Glycine supplies a building block for glutathione in a focused supplement, with moderate value for the amount provided.

AI assessment of the formula, label and price. How scoring works

Nutrient Quality20

The specific glycine preparation is unstated, so its quality remains uncertain. The declared amount alone does not identify a particular preparation advantage.

Ingredient Transparency63

The glycine amount is disclosed, allowing serving quantities to be compared. Its specific preparation is unstated, limiting comparisons between products.

Value For Money60

Glycine offers moderate value for the amount supplied. Its cost is neither a clear strength nor a major drawback.

Customer Satisfaction70

Customer feedback is very positive. The small review pool gives a narrow picture of how widely that satisfaction is shared.

Product Focus79

Glycine has roles in cellular processes and glutathione production. Those roles do not establish routine relief of inflammation or standalone toxin clearance.

Format
Capsule
Container
180 Capsule(s)
Per serving
$0.58
Customer rating
4.7 · 32 ratings
Report analysis

Goals

Impact
High effect
B+ Ingredient FitD- PathwaysB+ EvidenceA+ Formulation Logic
Glycine · 1500 mg
Study evidence
Glycine Supportive 5 studies
Inflammation
Impact
Highest effect
B+ Ingredient FitD- PathwaysA+ EvidenceA+ Formulation Logic
Glycine · 1500 mg
Study evidence
Glycine Supportive 7 studies

Ingredients

IngredientAmount per servingScore
Calories
5 Calorie(s)
Glycine
1500 mg 45
Gluten Free Adults 18–50
Report overview
Glycine · 1500 mg OverallScore45
F Active Ingredient Quality & BioavailabilityB+ Dose, Safety & Label TransparencyC Value
A serving provides 1500 mg of glycine. The cost per gram of glycine is moderate. The available details do not establish a glycine grade or purity certification.
How this ingredient is rated

Active Ingredient Quality & Bioavailability0

The available details do not establish a glycine grade or purity certification.
Glycine Sourcing and Purity Standards
The available details do not establish a glycine grade or purity certification.

Dose, Safety & Label Transparency82

The glycine amount is stated as 1500 mg per serving. Ordinary excipients or capsule materials are listed.
Clinically Relevant Dosage
The serving provides 1500 mg of glycine.
Label Transparency and Yield Disclosure
The glycine amount is stated as 1500 mg per serving.
Clean Label and Excipient Quality
Ordinary excipients or capsule materials are listed.

Value60

The cost per gram of glycine is moderate.
Cost Efficiency per 1,000mg of Glycine
The cost per gram of glycine is moderate.
Report alternatives

Sources

Published studies used for the product analysis and the top-ranked studies for each ingredient and goal.

  1. Glycine treatment decreases proinflammatory cytokines and increases interferon-gamma in patients with type 2 diabetes.
    Cruz M; Maldonado-Bernal C; Mondragón-Gonzalez R; Sanchez-Barrera R; Wacher NH; Carvajal-Sandoval G; Kumate J · Journal of endocrinological investigation · 2009
    Randomized trial74 participantsInflammation forGlycine
  2. Effect of oral glycine on the clinical, spirometric and inflammatory status in subjects with cystic fibrosis: a pilot randomized trial.
    Vargas MH; Del-Razo-Rodríguez R; López-García A; Lezana-Fernández JL; Chávez J; Furuya MEY; Marín-Santana JC · BMC pulmonary medicine · 2018
    Randomized trial13 participantsInflammation forGlycine
  3. Subgingival air polishing (glycine powder) versus minocycline hydrochloride: efficacy in residual periodontal pockets following endoscope-assisted scaling and root planing.
    Guo X; Bai H; Lu X; Guo J; Qi Y; Huo X; Li S · Clinical oral investigations · 2026
    Randomized trial80 participantsInflammation forGlycine
  4. Long-term Implant Maintenance: A Systematic Review of Home and Professional Care Strategies in Supportive Implant Therapy.
    Araújo TG; Moreira CS; Neme RA; Luan H; Bertolini M · Brazilian dental journal · 2024
    Systematic review13 studies pooledInflammation forGlycine
  5. Analysis of the factors influencing the occurrence of peri-implantitis in patients with implant-supported restoration and study on the maintenance effect of subgingival sandblasting.
    Pan T; Meng W; Zhang M; Xie Y; Chen Z; Zhou M; Yin L; Xie H · BMC oral health · 2026
    Randomized trial198 participantsInflammation forGlycine
  6. The impact of obesity-associated glycine deficiency on the elimination of endogenous and exogenous metabolites via the glycine conjugation pathway.
    Tan HC; Hsu JW; Tai ES; Chacko S; Kovalik JP; Jahoor F · Frontiers in endocrinology · 2024
    Cohort study42 participantsLiver & Detox forGlycine
  7. Metabolic impact of dietary glycine supplementation in individuals with severe obesity.
    Tan HC; Hsu JW; Tai ES; Chacko S; Wu V; Yen PM; Kovalik JP; Jahoor F · Scientific reports · 2025
    Single-arm trial19 participantsLiver & Detox forGlycine
  8. Contribution towards a Metabolite Profile of the Detoxification of Benzoic Acid through Glycine Conjugation: An Intervention Study.
    Irwin C; van Reenen M; Mason S; Mienie LJ; Westerhuis JA; Reinecke CJ · PloS one · 2017
    Non-randomized trial21 participantsLiver & Detox forGlycine
  9. Glycine conjugation of para-aminobenzoic acid (PABA): a quantitative test of liver function.
    Furuya KN; Durie PR; Roberts EA; Soldin SJ; Verjee Z; Yung-Jato L; Giesbrecht E; Ellis L · Clinical biochemistry · 1996
    Methods validation study74 participantsLiver & Detox forGlycine
  10. The treatment of isovaleric acidemia with glycine supplement
    M Naglak, R Salvo, K Madsen, P Dembure, L Elsas · Pediatric research · 1988
    Non-randomized trial2 participantsLiver & Detox forGlycine