Brain

Brain

Host Defense MycoBotanicals4.6 (3,105 ratings)
Format:Capsule Quantity: 60 Capsule(s) · 30 servings
Goals

Product analysis

50 out of 100

Brain may offer modest support for some memory and attention tasks. The bacopa, ginkgo and mushroom preparations are not clearly identified, so results from specific extracts cannot be assumed.

AI assessment of the formula, label and price. How scoring works

Nutrient Quality20

The botanical and mushroom preparations are unspecified, leaving their quality uncertain. That prevents a meaningful comparison with clearly identified extracts.

Ingredient Transparency63

Individual ingredient amounts are disclosed, helping with serving comparisons. Preparation details are missing, limiting comparisons with specific extracts.

Value For Money49

The serving price offers moderate value, with a more favorable comparison for cordyceps. That does not establish the value of every ingredient or compensate for uncertain preparations.

Customer Satisfaction85

Customer ratings are positive across thousands of reviews. They do not establish dependable improvements in memory or focus.

Product Focus63

Memory and attention are the clearest intended purposes of the formula. The support is modest and depends on preparations that are not clearly identified here.

Format
Capsule
Container
60 Capsule(s)
Per serving
$0.79
Customer rating
4.6 · 3,105 ratings
Report analysis

Goals

Productivity Boost
Impact
Moderate effect
B Ingredient FitF PathwaysD- EvidenceA+ Formulation Logic
Cordyceps · 50 mgCordyceps · 50 mgCordyceps · 50 mg

Ginkgo, bacopa and lion’s mane have some relevance to memory and information processing. Bacopa’s benefits relate to repeated use, and its unspecified extract limits comparison with tested preparations; lion’s mane findings remain preliminary. The 50 mg of cordyceps is too small to make a meaningful contribution in the saved assessment.

How this product is rated for Productivity Boost

Ingredient fit79

Three memory-related ingredients provide the main fit, alongside reishi for other purposes. Ginkgo contributes most clearly at its declared amount; bacopa and lion’s mane provide more partial dose support.
Goal fit
Three memory-related ingredients provide the main fit, alongside reishi for other purposes.
Dose adequacy
Ginkgo contributes most clearly at its declared amount; bacopa and lion’s mane provide more partial dose support.

Pathways17

Memory-related processes are the strongest area, with a smaller connection to acetylcholine signalling.
Depth
Memory-related processes are the strongest area, with a smaller connection to acetylcholine signalling.
Breadth
No area reaches the saved threshold for broad support across several mechanisms.

Evidence44

Ginkgo provides the strongest evidence among the ingredients assessed at meaningful amounts. Bacopa is not identified as a tested preparation; the saved assessment accepts the ginkgo and lion’s mane preparations.
Evidence strength
Ginkgo provides the strongest evidence among the ingredients assessed at meaningful amounts.
Studied preparation
Bacopa is not identified as a tested preparation; the saved assessment accepts the ginkgo and lion’s mane preparations.

Formulation logic100

All three assessed ingredients meet the saved minimum amount. No ingredient conflicts were identified in the saved checks.
Partner coverage
The assessed ingredients can contribute on their own or have their required partner.
Conflicts
No ingredient conflicts were identified in the saved checks.
Effective doses
All three assessed ingredients meet the saved minimum amount.
Study evidence
Bacopa Supportive 12 studies
Cordyceps Not classified 1 study
Ginkgo Supportive 20 studies
Cognitive Support
Impact
High effect
C+ Ingredient FitD- PathwaysB- EvidenceA+ Formulation Logic
Bacopa · 250 mgHericium mushroom · 300 mg

Bacopa has selected memory findings after repeated use of specific extracts, while ginkgo has preliminary preparation-specific attention findings. Neither preparation is identified here, limiting transfer of those results. Hericium has isolated findings from a particular mushroom complex, which do not establish broad benefits from generic mushroom material. These ingredients have cognitive relevance, but the saved findings should not be read as proof of general memory improvement.

How this product is rated for Cognitive Support

Ingredient fit66

The formula’s relevance depends on both its ingredient focus and the usable declared amounts. The declared amounts provide only partial comparison coverage; smaller or unresolved amounts limit the findings.
Goal fit
The formula mixes ingredients recognized for this goal with other actives, so its focus extends beyond cognition.
Dose adequacy
The declared amounts provide only partial comparison coverage; smaller or unresolved amounts limit the findings.

Pathways40

The strongest saved connection concerns cerebral blood flow; mechanism coverage alone does not establish cognitive improvement. The saved findings concentrate on one mechanism, limiting breadth across the other cognitive aspects.
Depth
The strongest saved connection concerns cerebral blood flow; mechanism coverage alone does not establish cognitive improvement.
Breadth
The saved findings concentrate on one mechanism, limiting breadth across the other cognitive aspects.

Evidence70

Hericium mushroom leads the saved evidence finding, while its specific scientific limitations still constrain expected cognitive benefits. Preparation matching is incomplete for Bacopa, Ginkgo; findings for particular studied materials cannot automatically transfer.
Evidence strength
Hericium mushroom leads the saved evidence finding, while its specific scientific limitations still constrain expected cognitive benefits.
Studied preparation
Preparation matching is incomplete for Bacopa, Ginkgo; findings for particular studied materials cannot automatically transfer.

Formulation logic100

No configured conflict was identified in the supplied facts. All counted ingredients reach the saved amount threshold; that comparison is not proof of a clinically effective dose.
Partner coverage
No missing required partner reduced the findings; this does not establish synergy or added benefit from combining ingredients.
Conflicts
No configured conflict was identified in the supplied facts.
Effective doses
All counted ingredients reach the saved amount threshold; that comparison is not proof of a clinically effective dose.
Study evidence
Bacopa Supportive 30 studies
Ginkgo Supportive 87 studies
Brain Health
Impact
High effect
C+ Ingredient FitC PathwaysC EvidenceA+ Formulation Logic
Bacopa · 250 mg

Bacopa has a modest memory and learning role when a separately identified studied extract is used; this product's unidentified extract cannot establish that match. Ginkgo and Hericium receive saved contributions, but their supplied evidence does not establish general cognitive protection. The mushroom declaration cannot establish equivalence to the particular preparation used in the small, mixed young-adult trial.

How this product is rated for Brain Health

Ingredient fit69

Bacopa, Ginkgo, Hericium mushroom provide the included ingredients connected to this goal, alongside ingredients aimed at other purposes.
Goal fit
Bacopa, Ginkgo, Hericium mushroom provide the included ingredients connected to this goal, alongside ingredients aimed at other purposes.
Dose adequacy
The included amounts provide partial support overall; some amounts fall below the saved comparison's full amount allowance.

Pathways63

The strongest saved connection is to cerebral energy metabolism, without proving a clinical cognitive benefit. The saved findings cover two brain processes, with other aspects remaining limited.
Depth
The strongest saved connection is to cerebral energy metabolism, without proving a clinical cognitive benefit.
Breadth
The saved findings cover two brain processes, with other aspects remaining limited.

Evidence64

Hericium mushroom leads the saved evidence finding; its specific population and outcome limits still apply. Bacopa lacks a match to a studied preparation; the other counted ingredients retain their saved preparation findings.
Evidence strength
Hericium mushroom leads the saved evidence finding; its specific population and outcome limits still apply.
Studied preparation
Bacopa lacks a match to a studied preparation; the other counted ingredients retain their saved preparation findings.

Formulation logic100

The saved findings show no missing partner or configured conflict. The counted ingredients meet the saved minimum amount threshold, which is not a proven effective dose.
Partner coverage
The counted ingredients have no unmet partner requirement in the supplied findings.
Conflicts
No configured ingredient conflict was found; this is not a comprehensive safety assessment.
Effective doses
The counted ingredients meet the saved minimum amount threshold, which is not a proven effective dose.
Study evidence
Bacopa Supportive 17 studies
Ginkgo Supportive 90 studies
Mental Focus
Impact
Moderate effect
B+ Ingredient FitD- PathwaysD EvidenceA+ Formulation Logic

Ginkgo has mixed attention findings, while bacopa and lion’s mane have limited, preparation-specific cognitive evidence. The declared 250 mg bacopa and 300 mg lion’s mane amounts do not imply equivalent effects across powders and extracts.

How this product is rated for Mental Focus

Ingredient fit81

The saved assessment finds relevant ingredients within a formula serving several purposes. The assessed amounts provide partial support against the saved dose references (82.4 out of 100).
Goal fit
The saved assessment finds relevant ingredients within a formula serving several purposes.
Dose adequacy
The assessed amounts provide partial support against the saved dose references (82.4 out of 100).

Pathways44

The strongest saved coverage concerns cerebral energy supply, with partial coverage. One mechanism reaches the saved coverage threshold, so support is concentrated in one aspect of focus.
Depth
The strongest saved coverage concerns cerebral energy supply, with partial coverage.
Breadth
One mechanism reaches the saved coverage threshold, so support is concentrated in one aspect of focus.

Evidence49

Ginkgo leads the saved evidence comparison at an assessed amount. Some qualifying ingredients do not match the saved studied-preparation category: Bacopa, Hericium mushroom.
Evidence strength
Ginkgo leads the saved evidence comparison at an assessed amount.
Studied preparation
Some qualifying ingredients do not match the saved studied-preparation category: Bacopa, Hericium mushroom.

Formulation logic100

The assessed ingredients work independently or have their listed partner. No ingredient conflict is recorded in the saved assessment.
Partner coverage
The assessed ingredients work independently or have their listed partner.
Conflicts
No ingredient conflict is recorded in the saved assessment.
Effective doses
All assessed ingredients reach the saved minimum dose threshold.
Study evidence
Bacopa Supportive 13 studies
Ginkgo Supportive 28 studies

Ingredients

IngredientAmount per servingScore
Lion's Mane
300 mg 30
Bacopa (Bacopa monnieri) whole plant extract
250 mg 17
Reishi
150 mg
Gotu Kola (Centella asiatica) aerial parts extract
130 mg
Ginkgo (Ginkgo biloba) leaf extract
120 mg 50
Cordyceps
50 mg 54
Gluten Free Adults 18–50 Organic
Report overview
Ginkgo · 120 mg OverallScore50
F Composition And Label DisclosureA+ Composition And Label Disclosure
A serving provides 120 mg of ginkgo leaf extract. The saved facts do not provide flavone or terpene percentages, so those markers cannot be compared.
How this ingredient is rated

Composition and Label Disclosure0

The saved facts lack flavone and terpene percentages and a ginkgolic acid limit; their absence does not establish the actual levels.
Marker and Preparation Disclosure
The saved facts do not provide flavone or terpene percentages for the ginkgo preparation.
Declared Ginkgolic Acid Limit
The saved facts do not contain a qualifying ginkgolic acid limit; the actual level is unknown.

Composition and Label Disclosure100

The ginkgo amount is individually recorded as 120 mg per serving.
Individual Preparation Amount Disclosure
The selected serving contains 120 mg of ginkgo leaf extract.

Commercial Price and Usability

No value assessment was included for ginkgo.
F Composition And Label DisclosureD+ Composition And Label DisclosureD+ Commercial Price And Usability
A serving provides 300 mg of lion's mane mushroom. The saved facts do not specify the preparation or record a beta-glucan or polysaccharide percentage.
How this ingredient is rated

Composition and Label Disclosure0

The preparation is not specified in the saved facts. The saved facts do not record a beta-glucan or polysaccharide percentage.
Marker and Preparation Disclosure
The saved facts do not record a beta-glucan or polysaccharide percentage.

Composition and Label Disclosure50

The selected serving lists 300 mg of lion's mane mushroom.
Hericium Target Amount Disclosure
The selected serving lists 300 mg of lion's mane mushroom.

Commercial Price and Usability50

The whole product costs about $0.80 per serving.
Commercial Price per Labeled Serving
The whole product costs about $0.80 per serving.
Bacopa · 250 mg OverallScore17
F Composition And Label DisclosureD+ Commercial Price And Usability
A serving lists 250 mg of bacopa whole plant extract, but the saved facts do not include a bacoside percentage. A whole-product serving costs about $0.80.
How this ingredient is rated

Composition and Label Disclosure

No separate assessment was made in this category.

Composition and Label Disclosure0

A serving lists 250 mg of bacopa whole plant extract. No bacoside percentage is recorded in the saved facts.
Amount and Label Disclosure
A serving lists 250 mg of bacopa whole plant extract. No bacoside percentage is recorded in the saved facts.

Commercial Price and Usability50

A whole-product serving costs about $0.80.
Commercial Price per Labeled Serving
A whole-product serving costs about $0.80.
Report alternatives

Sources

Published studies used for the product analysis and the top-ranked studies for each ingredient and goal.

  1. Comparative effects of Bacopa monnieri and Ginkgo biloba on cognitive functions: A systematic review and network meta-analysis.
    Tiemtad P; Ingkaninan K; Temkitthawon P; Thimkorn P; Rattanachaisit N; Teaktong T; Dhippayom T · Phytomedicine : international journal of phytotherapy and phytopharmacology · 2026
    Meta-analysis2,107 participants29 studies pooledBrain Health Mental Focus forBacopa
  2. Meta-analysis of randomized controlled trials on cognitive effects of Bacopa monnieri extract.
    Kongkeaw C; Dilokthornsakul P; Thanarangsarit P; Limpeanchob N; Norman Scholfield C · Journal of ethnopharmacology · 2014
    Meta-analysis518 participants9 studies pooledBrain Health Mental Focus Productivity Boost forBacopa
  3. Comparative efficacy of Medhya Rasayana,Bacopa monnieri, and Centella asiatica in enhancing memory and IQ of 8-10 year-old healthy boys: A prakriti-based double-blind, randomized controlled trial.
    Verma J; Rathi R; Anamika; Rathi B; Pandey VB · Journal of Ayurveda and integrative medicine · 2025
    Randomized trial180 participantsBrain Health Cognitive Support forBacopa
  4. Plant-derived nootropics and human cognition: A systematic review.
    Lorca C; Mulet M; Arévalo-Caro C; Sanchez MÁ; Perez A; Perrino M; Bach-Faig A; Aguilar-Martínez A; Vilella E; Gallart-Palau X; Serra A · Critical reviews in food science and nutrition · 2023
    Systematic review256 studies pooledBrain Health forBacopa
  5. The effect of plant active substances on cognitive function in healthy older adults: a systematic review and network meta-analysis of randomized controlled trials.
    Feng X; Fan S; Wei F · Frontiers in pharmacology · 2026
    Meta-analysis1,861 participants25 studies pooledBrain Health Cognitive Support forBacopa
  6. Efficacy and adverse effects of ginkgo biloba for cognitive impairment and dementia: a systematic review and meta-analysis.
    Tan MS; Yu JT; Tan CC; Wang HF; Meng XF; Wang C; Jiang T; Zhu XC; Tan L · Journal of Alzheimer's disease : JAD · 2015
    Meta-analysis2,561 participants9 studies pooledBrain Health forGinkgo
  7. Efficacy of Ginkgo biloba extract EGb 761® in dementia with behavioural and psychological symptoms: A systematic review.
    von Gunten A; Schlaefke S; Überla K · The world journal of biological psychiatry : the official journal of the World Federation of Societies of Biological Psychiatry · 2017
    Meta-analysis1,628 participants4 studies pooledBrain Health Cognitive Support forGinkgo
  8. Ginkgo biloba extract EGb 761 is safe and effective in the treatment of mild dementia - a meta-analysis of patient subgroups in randomised controlled trials.
    Riepe M; Hoerr R; Schlaefke S · The world journal of biological psychiatry : the official journal of the World Federation of Societies of Biological Psychiatry · 2025
    Meta-analysis782 participants4 studies pooledBrain Health Productivity Boost forGinkgo
  9. Ginkgo biloba extract EGb 761® improves cognition and overall condition after ischemic stroke: Results from a pilot randomized trial.
    Cui M; You T; Zhao Y; Liu R; Guan Y; Liu J; Liu X; Wang X; Dong Q · Frontiers in pharmacology · 2023
    Randomized trial201 participantsBrain Health Productivity Boost forGinkgo
  10. Ginkgo biloba extract EGb 761® in dementia with neuropsychiatric features: a randomised, placebo-controlled trial to confirm the efficacy and safety of a daily dose of 240 mg.
    Herrschaft H; Nacu A; Likhachev S; Sholomov I; Hoerr R; Schlaefke S · Journal of psychiatric research · 2012
    Randomized trial410 participantsBrain Health forGinkgo
  11. Acute Effects of Naturally Occurring Guayusa Tea and Nordic Lion's Mane Extracts on Cognitive Performance.
    La Monica MB; Raub B; Ziegenfuss EJ; Hartshorn S; Grdic J; Gustat A; Sandrock J; Ziegenfuss TN · Nutrients · 2023
    Randomized trialBrain Health Productivity Boost forHericium mushroom
  12. Improvement of cognitive functions by oral intake of Hericium erinaceus.
    Saitsu Y; Nishide A; Kikushima K; Shimizu K; Ohnuki K · Biomedical research (Tokyo, Japan) · 2020
    Randomized trialBrain Health Cognitive Support forHericium mushroom
  13. Improving effects of the mushroom Yamabushitake (Hericium erinaceus) on mild cognitive impairment: a double-blind placebo-controlled clinical trial.
    Mori K; Inatomi S; Ouchi K; Azumi Y; Tuchida T · Phytotherapy research : PTR · 2009
    Randomized trial30 participantsBrain Health Cognitive Support forHericium mushroom
  14. A review of the effects of mushrooms on mood and neurocognitive health across the lifespan.
    Cha S; Bell L; Shukitt-Hale B; Williams CM · Neuroscience and biobehavioral reviews · 2024
    Systematic review34 studies pooledBrain Health forHericium mushroom
  15. Acute effects of a standardised extract of Hericium erinaceus (Lion's Mane mushroom) on cognition and mood in healthy younger adults: a double-blind randomised placebo-controlled study.
    Surendran G; Saye J; Binti Mohd Jalil S; Spreadborough J; Duong K; Shatwan IM; Lilley D; Heinrich M; Dodd GF; Surendran S · Frontiers in nutrition · 2025
    Randomized trial18 participantsBrain Health Mental Focus forHericium mushroom
  16. The cognitive-enhancing effects of Bacopa monnieri: a systematic review of randomized, controlled human clinical trials.
    Pase MP; Kean J; Sarris J; Neale C; Scholey AB; Stough C · Journal of alternative and complementary medicine (New York, N.Y.) · 2012
    Systematic review6 studies pooledCognitive Support Productivity Boost forBacopa
  17. A systematic review of the Ayurvedic medicinal herb Bacopa monnieri in child and adolescent populations.
    Kean JD; Downey LA; Stough C · Complementary therapies in medicine · 2017
    Systematic review5 studies pooledCognitive Support forBacopa
  18. Efficacy of Standardized Extract of Bacopa monnieri (Bacognize®) on Cognitive Functions of Medical Students: A Six-Week, Randomized Placebo-Controlled Trial.
    Kumar N; Abichandani LG; Thawani V; Gharpure KJ; Naidu MU; Venkat Ramana G · Evidence-based complementary and alternative medicine : eCAM · 2024
    Randomized trial60 participantsCognitive Support forBacopa
  19. Efficacy of ginkgo diterpene lactone meglumine on cognitive function in patients with acute ischemic stroke: a predefined exploratory analysis of a multicenter, double-blind, randomized controlled trial.
    Tian X; Xu Q; Xia X; Zhang Y; Meng X; Wang A · Journal of neurology · 2024
    Randomized trial3,163 participantsCognitive Support forGinkgo
  20. A placebo-controlled, double-blind, randomized trial of an extract of Ginkgo biloba for dementia. North American EGb Study Group.
    Le Bars PL; Katz MM; Berman N; Itil TM; Freedman AM; Schatzberg AF · JAMA · 1997
    Randomized trial309 participantsCognitive Support forGinkgo