St. John's Wort

St. John's Wort

Oregon's Wild Harvest4.4 (89 ratings)
Format:Capsule Quantity: 90 Capsule(s) · 30 servings
Goals
$26.36 $0.87 per serving
iHerbLowest$26.36Vitacost$26.36iHerb$26.36

Product analysis

54 out of 100

St. John's Wort is aimed at mood support, but extract differences leave its everyday benefits uncertain. It can reduce the effect of birth control pills, blood thinners and many other medicines.

AI assessment of the formula, label and price. How scoring works

Nutrient Quality40

Some extract details are named, but they do not establish how this preparation compares with particular studied extracts. Its form quality remains uncertain.

Ingredient Transparency80

The amount and some extract details are listed, helping identify the ingredient. Missing composition details still make its strength harder to compare.

Value For Money40

Value remains uncertain because a usable ingredient price comparison is unavailable. Unclear extract composition also limits comparison with other preparations.

Customer Satisfaction65

Customer feedback is strongly positive. The relatively small review pool limits how representative that feedback may be.

Product Focus57

The formula concentrates on mood, but effects from particular extracts cannot be assumed for this preparation. Medicine interactions are a concrete limitation when deciding whether it is suitable.

Format
Capsule
Container
90 Capsule(s)
Per serving
$0.87
Customer rating
4.4 · 89 ratings
Report analysis

Goals

Mood Support
Mood Support
Impact
Moderate effect
A+ Ingredient FitF PathwaysF EvidenceA+ Formulation Logic

St. John's wort has a connection with treating diagnosed depression using particular extracts, but that doesn't tell you whether this preparation improves everyday mood in healthy adults. Extracts aren't interchangeable. It can also weaken oral contraceptives, anticoagulants and many other medicines, so medication interactions materially affect its suitability.

How this product is rated for Mood Support

Ingredient fit100

St. John's Wort supplies the main mood connection. Its practical contribution depends on the context described here.
Goal fit
St. John's Wort supplies the main connection with mood here.
Dose adequacy
St. John's Wort provides 1050 mg per serving. The amount alone does not predict mood improvement.

Pathways16

The main connection involves chemical signals associated with mood; that role alone does not guarantee an emotional benefit.
Depth
The main connection involves chemical signals associated with mood; that role alone does not guarantee an emotional benefit.
Breadth
The ingredients relate to particular mood processes; this does not predict a broad improvement in emotional well-being.

Evidence27

Defined St. John's wort extracts concern diagnosed depression; benefit in healthy adults remains unclear.
Evidence strength
Defined St. John's wort extracts concern diagnosed depression; benefit in healthy adults remains unclear.
Studied preparation
St. John's Wort does not identify the defined preparation needed to transfer its effects.

Formulation logic100

No particular ingredient conflict is identified, and no additional partner is required by the described ingredient relationships.
Partner coverage
No additional partner is required by the ingredient relationships described here.
Conflicts
No particular conflict between the declared ingredients is identified.
Effective doses
St. John's Wort provides 1050 mg per serving. A declared amount does not guarantee an individual benefit.
Study evidence

Ingredients

IngredientAmount per servingScore
organic St. John's Wort (Flavonoids, Hypericins)
 1050 mg 50
Gluten Free Adults 18–50 Dairy Free Women Organic
Report overview
St. John's Wort (Flavonoids, Hypericins) · 1050 mg OverallScore50
D+ Composition And Label Disclosure
A serving lists 1050 mg of St. John's wort. A general warning is recorded, but its wording and any ingredient-specific details are not included in the saved facts.
How this ingredient is rated

Composition and Label Disclosure

No separate quality or bioavailability assessment is provided in the saved evaluation.

Composition and Label Disclosure50

A serving lists 1050 mg of St. John's wort. A general warning is recorded, but its wording and any ingredient-specific details are not included in the saved facts.
Explicit Label Detail
A general warning is recorded, but its wording and any ingredient-specific details are not included in the saved facts.

Commercial Price and Usability

The whole-product serving costs about $0.88; no separate value assessment is provided.
View ingredientView products
88 Performance

Full Spectrum St. John's Wort Extract 600 mg

Planetary Herbals
A standardized, substantial Saint John’s wort blend offers focused mood support with stronger potency clarity than nonstandardized options; its extract quality and goal fit provide a clearer option when the original has a weak, secondary, or opaque Saint John’s wort contribution. Saint John’s wort can weaken oral contraceptives and anticoagulants and can interact seriously with serotonergic antidepressants, so medication use needs clinician or pharmacist review.
84 Performance

Feeling Positive St. John's Wort 300 mg

Sundown
Marker standardization supports consistent extract quality, though the daily amount is moderate; its extract quality and goal fit provide a clearer option when the original has a weak, secondary, or opaque Saint John’s wort contribution. Saint John’s wort can weaken oral contraceptives and anticoagulants and can interact seriously with serotonergic antidepressants, so medication use needs clinician or pharmacist review.
83 Performance

St. John's Wort Extract 300 mg

Lake Avenue Nutrition
A hypericin-standardized aerial-parts extract gives useful potency clarity and focused mood support, though one serving may provide only a partial daily dose; its extract quality and goal fit provide a clearer option when the original has a weak, secondary, or opaque Saint John’s wort contribution. Saint John’s wort can weaken oral contraceptives and anticoagulants and can interact seriously with serotonergic antidepressants, so medication use needs clinician or pharmacist review.
90 Budget

St. John's Wort Extract

Swanson Superior Herbs
Marker standardization supports consistent extract quality, though the daily amount is moderate; the lower serving cost improves economy when the original has a weak, secondary, or opaque Saint John’s wort contribution. Saint John’s wort can weaken oral contraceptives and anticoagulants and can interact seriously with serotonergic antidepressants, so medication use needs clinician or pharmacist review.
90 Budget

St. John's Wort 300 mg

NOW
Marker standardization supports consistent extract quality, though the daily amount is moderate; the lower serving cost improves economy when the original has a weak, secondary, or opaque Saint John’s wort contribution. Saint John’s wort can weaken oral contraceptives and anticoagulants and can interact seriously with serotonergic antidepressants, so medication use needs clinician or pharmacist review.
89 Budget

St. John's Wort 300 mg

California Gold Nutrition EuroHerbs
A hypericin-standardized extract gives useful potency clarity and focused mood support, though one serving may provide only a partial daily dose; the lower serving cost improves economy when the original has a weak, secondary, or opaque Saint John’s wort contribution. Saint John’s wort can weaken oral contraceptives and anticoagulants and can interact seriously with serotonergic antidepressants, so medication use needs clinician or pharmacist review.
87 Value

St. John's Wort Extract 300 mg

Lake Avenue Nutrition
A hypericin-standardized aerial-parts extract gives useful potency clarity and focused mood support, though one serving may provide only a partial daily dose; the quality-to-cost balance is favorable when the original has a weak, secondary, or opaque Saint John’s wort contribution. Saint John’s wort can weaken oral contraceptives and anticoagulants and can interact seriously with serotonergic antidepressants, so medication use needs clinician or pharmacist review.
86 Value

St. John's Wort 300 mg

Nature's Bounty
Marker standardization supports consistent extract quality, though the daily amount is moderate; the quality-to-cost balance is favorable when the original has a weak, secondary, or opaque Saint John’s wort contribution. Saint John’s wort can weaken oral contraceptives and anticoagulants and can interact seriously with serotonergic antidepressants, so medication use needs clinician or pharmacist review.
86 Value

Perika St. John's Wort

Nature's Way
The named extract supports consistent quality, though the daily amount is moderate; the quality-to-cost balance is favorable when the original has a weak, secondary, or opaque Saint John’s wort contribution. Saint John’s wort can weaken oral contraceptives and anticoagulants and can interact seriously with serotonergic antidepressants, so medication use needs clinician or pharmacist review.
Report alternatives

Sources

Published studies used for the product analysis and the top-ranked studies for each ingredient and goal.

  1. St John's wort for major depression.
    Linde K; Berner MM; Kriston L · The Cochrane database of systematic reviews · 2009
    Systematic review5,489 participants29 studies pooledMood Support forSt. John's Wort
  2. Efficacy of St. John's wort extract WS 5570 in major depression: a double-blind, placebo-controlled trial.
    Lecrubier Y; Clerc G; Didi R; Kieser M · The American journal of psychiatry · 2002
    Randomized trial375 participantsMood Support forSt. John's Wort
  3. A systematic review and meta-analysis of Hypericum perforatum in depression: a comprehensive clinical review.
    Whiskey E; Werneke U; Taylor D · International clinical psychopharmacology · 2002
    Meta-analysis22 studies pooledMood Support forSt. John's Wort
  4. Efficacy and tolerability of hypericum extract WS 5572 versus placebo in mildly to moderately depressed patients. A randomized double-blind multicenter clinical trial.
    Kalb R; Trautmann-Sponsel RD; Kieser M · Pharmacopsychiatry · 2001
    Randomized trial72 participantsMood Support forSt. John's Wort
  5. Complementary therapies for clinical depression: an overview of systematic reviews.
    Haller H; Anheyer D; Cramer H; Dobos G · BMJ open · 2020
    Systematic review26 studies pooledMood Support forSt. John's Wort