Buffered Vitamin C Powder

Buffered Vitamin C Powder

Life Extension4.7 (1,108 ratings)
Format:Powder Quantity: 454 Gram(s) · 84 servings
Goals

Product analysis

68 out of 100

Buffered Vitamin C Powder supplies vitamin C that supports normal immune function and collagen formation, at a low cost for the amount provided.

AI assessment of the formula, label and price. How scoring works

Nutrient Quality36

Quality remains uncertain for most of the nutrient contributions. The potassium carbonate form is less favorable, while naming the other forms alone does not establish their quality.

Ingredient Transparency100

The amount and form are clearly disclosed. You can compare what a serving provides without guessing the active ingredient.

Value For Money70

The vitamin C contribution is inexpensive for the amount supplied, and the potassium-related serving cost is also favorable. Value for the other minerals remains uncertain.

Customer Satisfaction81

Customer feedback is very positive. The large review pool gives a useful view of satisfaction, without establishing health benefits.

Product Focus71

Vitamin C supplies the clearest support for normal immune, antioxidant and collagen functions. The 4,000 mg serving does not establish extra benefit or safety, and the smaller mineral amounts add only limited nutritional support.

Format
Powder
Container
454 Gram(s)
Per serving
$0.25
Customer rating
4.7 · 1,108 ratings
Report analysis

Goals

Immunity
Impact
High effect
B- Ingredient FitC PathwaysA+ EvidenceA+ Formulation Logic
Magnesium · 55 mgVitamin C · 4000 mgZinc · 2 mg
Study evidence
Magnesium Supportive 8 studies
Vitamin C Supportive 53 studies
Zinc Supportive 73 studies
Everyday Health
Impact
High effect
A Ingredient FitD+ PathwaysB- EvidenceA+ Formulation Logic
Magnesium · 55 mgZinc · 2 mgVitamin C · 4000 mg
Study evidence
Magnesium Supportive 114 studies
Vitamin C Supportive 56 studies
Zinc Supportive 60 studies
Skin Health
Impact
High effect
C+ Ingredient FitF PathwaysA+ EvidenceA+ Formulation Logic
Zinc · 2 mgVitamin C · 4000 mg
Study evidence
Vitamin C Supportive 53 studies
Zinc Supportive 66 studies
Cardiovascular Support
Impact
Highest effect
B Ingredient FitB PathwaysA- EvidenceA+ Formulation Logic
Potassium · 365 mgMagnesium · 55 mgVitamin C · 4000 mg
Study evidence
Magnesium Supportive 123 studies
Potassium Supportive 117 studies
Vitamin C Supportive 101 studies
Inflammation
Impact
High effect
B- Ingredient FitD+ PathwaysA- EvidenceA+ Formulation Logic
Vitamin C · 4000 mg
Study evidence
Magnesium Supportive 41 studies
Vitamin C Supportive 50 studies
Zinc Supportive 64 studies
Impact
Moderate effect
C+ Ingredient FitF PathwaysC- EvidenceA+ Formulation Logic
Magnesium · 55 mg
Study evidence
Magnesium Supportive 158 studies
Potassium Supportive 182 studies
Eye Health
Impact
High effect
C+ Ingredient FitD PathwaysC+ EvidenceA+ Formulation Logic
Zinc · 2 mgVitamin C · 4000 mg
Study evidence
Vitamin C Disputed 24 studies
Zinc Supportive 39 studies

Ingredients

IngredientAmount per servingScore
Vitamin C (Ascorbic Acid)
4000 mg 62
Calcium (Calcium Carbonate)
145 mg
Magnesium (Magnesium Carbonate)
55 mg
Zinc (Zinc Gluconate)
2 mg
Potassium (Potassium Carbonate)
365 mg 59
Gluten Free Adults 18–50 Vegetarian
Report overview
F Active Ingredient Quality & BioavailabilityB Dose, Safety & Label TransparencyA+ Value
Each serving lists 365 mg of potassium. The cost per serving is low. The source is potassium carbonate.
How this ingredient is rated

Active Ingredient Quality & Bioavailability20

The source is potassium carbonate.
Potassium Form Quality
The source is potassium carbonate.

Dose, Safety & Label Transparency78

The potassium amount is listed as 365 mg per serving, without explicit elemental-potassium wording.
Potassium Dosage Potency
Each serving lists 365 mg of potassium.
Elemental Yield Transparency
The potassium amount is listed as 365 mg per serving, without explicit elemental-potassium wording.

Value100

The cost per serving is low.
Potassium Value Efficiency
The cost per serving is low.
F Active Ingredient Quality & BioavailabilityC+ Dose, Safety & Label TransparencyA+ Value
A serving provides 4000 mg of vitamin C at a low cost per gram. It uses ascorbic acid, an unbuffered form. At this high amount, absorption efficiency falls and diarrhea risk increases.
How this ingredient is rated

Active Ingredient Quality & Bioavailability39

Vitamin C comes from ascorbic acid. Ascorbic acid is an unbuffered acid form.
Vitamin C Chemical Form & Delivery System
Vitamin C comes from ascorbic acid.
Gastric Comfort & pH Balance
Ascorbic acid is an unbuffered acid form.

Dose, Safety & Label Transparency66

A serving provides 4000 mg of vitamin C. At this high amount, absorption efficiency falls and diarrhea risk increases. The available other-ingredient panel has no flagged additives.
Optimal Dosage Targeting
A serving provides 4000 mg of vitamin C. At this high amount, absorption efficiency falls and diarrhea risk increases.
Purity & Excipient Quality
The available other-ingredient panel has no flagged additives.
Mineral & Source Transparency
The vitamin C amount and ascorbic acid source are stated.

Value100

The cost per gram of vitamin C is low.
Price per Gram of Vitamin C
The cost per gram of vitamin C is low.
Report alternatives

Sources

Published studies used for the product analysis and the top-ranked studies for each ingredient and goal.

  1. Circulating and dietary magnesium and risk of cardiovascular disease: a systematic review and meta-analysis of prospective studies.
    Del Gobbo LC; Imamura F; Wu JH; de Oliveira Otto MC; Chiuve SE; Mozaffarian D · The American journal of clinical nutrition · 2013
    Meta-analysis313,041 participants16 studies pooledCardiovascular Support forMagnesium
  2. Magnesium and the risk of cardiovascular events: a meta-analysis of prospective cohort studies.
    Qu X; Jin F; Hao Y; Li H; Tang T; Wang H; Yan W; Dai K · PloS one · 2013
    Meta-analysis532,979 participants19 studies pooledCardiovascular Support forMagnesium
  3. Quantitative Association Between Serum/Dietary Magnesium and Cardiovascular Disease/Coronary Heart Disease Risk: A Dose-Response Meta-analysis of Prospective Cohort Studies.
    Zhao L; Hu M; Yang L; Xu H; Song W; Qian Y; Zhao M · Journal of cardiovascular pharmacology · 2020
    Meta-analysis544,581 participants18 studies pooledCardiovascular Support Heart Health forMagnesium
  4. Comparative Efficacy of Nutraceuticals on Endothelial Function: A Systematic Review and Network Meta-Analysis.
    Norouzzadeh M; Rashedi MH; Mahdavi-Mazdeh G; Kosari A; Shahinfar H · Current atherosclerosis reports · 2026
    Meta-analysisCardiovascular Support Heart Health forMagnesium
  5. Serum magnesium, mortality, and cardiovascular disease in chronic kidney disease and end-stage renal disease patients: a systematic review and meta-analysis.
    Xiong J; He T; Wang M; Nie L; Zhang Y; Wang Y; Huang Y; Feng B; Zhang J; Zhao J · Journal of nephrology · 2020
    Meta-analysis200,934 participants20 studies pooledCardiovascular Support forMagnesium
  6. Sex-specific associations between sodium and potassium intake and overall and cause-specific mortality: a large prospective U.S. cohort study, systematic review, and updated meta-analysis of cohort studies.
    Gan L; Zhao B; Inoue-Choi M; Liao LM; Graubard BI; Weinstein SJ; Albanes D; Huang J · BMC medicine · 2024
    Meta-analysis416,104 participantsCardiovascular Support forPotassium
  7. Potassium intake, stroke, and cardiovascular disease a meta-analysis of prospective studies.
    D'Elia L; Barba G; Cappuccio FP; Strazzullo P · Journal of the American College of Cardiology · 2011
    Meta-analysis247,510 participants11 studies pooledCardiovascular Support Heart Health forPotassium
  8. Blood pressure response to changes in sodium and potassium intake: a metaregression analysis of randomised trials.
    Geleijnse JM; Kok FJ; Grobbee DE · Journal of human hypertension · 2003
    Meta-analysis27 studies pooledCardiovascular Support forPotassium
  9. Twenty-Four-Hour Urinary Sodium and Potassium Excretion and Their Associations With Blood Pressure Among Adults in China: Baseline Survey of Action on Salt China.
    Li Y; Zhang P; Wu J; Ma J; Xu J; Zhang X; Luo R; Liu M; Sun Y; Li X; Tan M; He FJ; MacGregor GA; Li X · Hypertension (Dallas, Tex. : 1979) · 2021
    Cross-sectional study5,353 participantsCardiovascular Support forPotassium
  10. Dietary Sodium and Potassium Intake and Risk of Non-Fatal Cardiovascular Diseases: The Million Veteran Program.
    Wang DD; Li Y; Nguyen XT; Song RJ; Ho YL; Hu FB; Willett WC; Wilson PWF; Cho K; Gaziano JM; Djoussé L; On Behalf Of The Va Million Veteran Program · Nutrients · 2022
    Cohort study180,156 participantsCardiovascular Support forPotassium
  11. Vitamin C may reduce troponin and CKMB levels after PCI and CABG: a meta-analysis.
    Rozemeijer S; Hemilä H; van Baaren M; de Man AME · BMC cardiovascular disorders · 2023
    Meta-analysis872 participants7 studies pooledCardiovascular Support forVitamin C
  12. Vitamin C improves endothelium-dependent vasodilation by restoring nitric oxide activity in essential hypertension.
    Taddei S; Virdis A; Ghiadoni L; Magagna A; Salvetti A · Circulation · 1998
    Clinical trial49 participantsCardiovascular Support forVitamin C
  13. Vitamin C supplementation improves blood pressure and oxidative stress after acute exercise in patients with poorly controlled type 2 diabetes mellitus: A randomized, placebo-controlled, cross-over study.
    Boonthongkaew C; Tong-Un T; Kanpetta Y; Chaungchot N; Leelayuwat C; Leelayuwat N · The Chinese journal of physiology · 2021
    Randomized trial24 participantsCardiovascular Support forVitamin C
  14. Vascular benefits of vitamin C supplementation against fine particulate air pollution in healthy adults: A double-blind randomised crossover trial.
    Ren J; Liang J; Wang J; Yin B; Zhang F; Li X; Zhu S; Tian H; Cui Q; Song J; Liu G; Ling W; Ma Y · Ecotoxicology and environmental safety · 2022
    Randomized trial58 participantsCardiovascular Support forVitamin C
  15. Ascorbic acid reduces blood pressure and arterial stiffness in type 2 diabetes.
    Mullan BA; Young IS; Fee H; McCance DR · Hypertension (Dallas, Tex. : 1979) · 2003
    Randomized trial30 participantsCardiovascular Support forVitamin C
  16. Perioperative systemic magnesium to minimize postoperative pain: a meta-analysis of randomized controlled trials.
    De Oliveira GS; Castro-Alves LJ; Khan JH; McCarthy RJ · Anesthesiology · 2013
    Meta-analysis1,257 participants20 studies pooledEveryday Health forMagnesium
  17. Long-term outcome after intravenous magnesium sulphate in suspected acute myocardial infarction: the second Leicester Intravenous Magnesium Intervention Trial (LIMIT-2).
    Woods KL; Fletcher S · Lancet (London, England) · 1994
    Randomized trial2,316 participantsEveryday Health forMagnesium
  18. Association of magnesium sulfate use with mortality in critically ill patients with sepsis: a retrospective propensity score-matched cohort study.
    Gu WJ; Duan XJ; Liu XZ; Cen Y; Tao LY; Lyu J; Yin HY · British journal of anaesthesia · 2023
    Cohort study10,999 participantsEveryday Health forMagnesium
  19. Hypomagnesemia and Mortality in Incident Hemodialysis Patients.
    Li L; Streja E; Rhee CM; Mehrotra R; Soohoo M; Brunelli SM; Kovesdy CP; Kalantar-Zadeh K · American journal of kidney diseases : the official journal of the National Kidney Foundation · 2016
    Cohort study9,359 participantsEveryday Health forMagnesium
  20. The effects of magnesium supplementation on abnormal uterine bleeding, alopecia, quality of life, and acne in women with polycystic ovary syndrome: a randomized clinical trial.
    Jaripur M; Ghasemi-Tehrani H; Askari G; Gholizadeh-Moghaddam M; Clark CCT; Rouhani MH · Reproductive biology and endocrinology : RB&E · 2022
    Randomized trial64 participantsEveryday Health forMagnesium