Glucosamine Chondroitin Complex plus MSM

Glucosamine Chondroitin Complex plus MSM

21st Century4.8 (10,853 ratings)
Format:Tablet Quantity: 120 Tablet(s) · 60 servings
Goals
$22.99 $0.38 per serving

Product analysis

49 out of 100

Glucosamine Chondroitin Complex plus MSM combines several ingredients for people seeking a broad formula. Its unnamed blend makes it difficult to judge exactly what the combination provides.

AI assessment of the formula, label and price. How scoring works

Nutrient Quality28

Manganese sulfate and sodium borate are less favorable source choices. The proprietary blend and several other preparations lack enough detail for a firm quality conclusion.

Ingredient Transparency60

Amounts are listed for the declared entries. Most preparations and the proprietary blend components are unspecified, making the full formula harder to compare.

Value For Money45

Manganese compares favorably on serving cost, while boron is less economical. Value remains uncertain for other ingredients, so those mineral comparisons do not settle the value of the full formula.

Customer Satisfaction93

Customer feedback is very positive. Many reviews provide a broad picture of satisfaction.

Product Focus37

The clearest nutritional connection is boron’s role in mineral handling, with limited evidence for routine bone benefits. The unidentified blend leaves the complete ingredient count uncertain, and testosterone benefits remain unclear.

Format
Tablet
Container
120 Tablet(s)
Per serving
$0.38
Customer rating
4.8 · 10,853 ratings
Report analysis

Goals

Everyday Health
Impact
Moderate effect
D+ Ingredient FitF PathwaysB+ EvidenceA+ Formulation Logic
Boron · 3 mgVitamin C · 60 mg
Study evidence
Boron Supportive 6 studies
Vitamin C Supportive 56 studies
Impact
Moderate effect
D Ingredient FitF PathwaysC EvidenceA+ Formulation Logic
Boron · 3 mg
Study evidence
Boron Disputed 3 studies
Bone Health
Impact
High effect
B- Ingredient FitC- PathwaysA- EvidenceA+ Formulation Logic
Manganese · 2 mgBoron · 3 mgVitamin C · 60 mg
Study evidence
Boron Supportive 5 studies
Manganese Adverse 12 studies
Vitamin C Supportive 46 studies

Ingredients

IngredientAmount per servingScore
Calories
10 Calorie(s)
Total Carbohydrate
2 Gram(s)
Vitamin C (Ascorbic Acid)
60 mg
Manganese (Manganese Sulfate)
2 mg 66
Sodium
50 mg
Glucosamine Hydrochloride
1500 mg
Proprietary Blend
1103 mg
Boswellia serrata extract
100 mg 0
Boron (Sodium Borate)
3 mg 58
Adults 18–50
Report overview
D- Active Ingredient Quality & BioavailabilityA- Dose, Safety & Label TransparencyB+ Value
Each serving provides 2 mg of manganese at a moderate cost per serving. The source is Manganese Sulfate.
How this ingredient is rated

Active Ingredient Quality & Bioavailability40

The manganese comes from Manganese Sulfate.
Manganese Chemical Form
The stated source is Manganese Sulfate.

Dose, Safety & Label Transparency86

The serving provides 2 mg of manganese. Both the amount and source are stated.
Manganese Dosage Efficacy & Safety
A serving contains 2 mg of manganese.
Elemental Weight Disclosure
The label states the manganese amount and source.

Value80

The cost per serving is moderate.
Price per Serving vs. Median
The cost per serving is moderate.
F Active Ingredient Quality & BioavailabilityA+ Dose, Safety & Label TransparencyF Value
3 mg of boron per serving comes at a high cost per 3 mg. The amount falls in the range described for general mineral support. The boron comes from Sodium Borate.
How this ingredient is rated

Active Ingredient Quality & Bioavailability29

The boron comes from Sodium Borate. No specific purity or third-party mineral testing claim is stated.
Boron Form & Bioavailability
The boron comes from Sodium Borate.
Trademarked & High-Purity Sources
No specific purity or third-party mineral testing claim is stated.

Dose, Safety & Label Transparency100

3 mg per serving provides boron within the 3–6 mg range described for general mineral support. The elemental boron amount and source are stated.
Elemental Dose Transparency
The elemental boron amount and source are stated.
Dosage Efficacy & Safety Margin
3 mg per serving provides boron within the 3–6 mg range described for general mineral support.

Value30

The cost per 3 mg of boron is high.
Price per 3mg Elemental Boron
The cost per 3 mg of boron is high.
Boswellia · 100 mg OverallScore0
F Composition And Label DisclosureF Composition And Label Disclosure
The serving contains Boswellia serrata and 100 mg of its extract, but the total boswellia amount is unclear. The boswellic acid percentages are also unknown. Cost is not assessed.
How this ingredient is rated

Composition and Label Disclosure0

The available information does not give a boswellic acid percentage.
Marker and Preparation Disclosure
The boswellic acid percentage is not available.

Composition and Label Disclosure0

The extract amount is known, but the total across both sources is unclear.
Boswellia Amount and Marker Disclosure
The extract supplies 100 mg, but the amount of the other Boswellia serrata source is unknown.

Commercial Price and Usability

Cost was not assessed.
Report alternatives

Sources

Published studies used for the product analysis and the top-ranked studies for each ingredient and goal.

  1. [Comparative study of the urinary excretion of boron, calcium, magnesium and phosphorus in postmenopausal women with and without osteoporosis].
    José Ramón V; Mora Mora M; Marino Alarcón O; Hernández G; Josefina Linares L; Urdaneta Romero H; Arévalo González E · Investigacion clinica · 2013
    Case-control study45 participantsBone Health forBoron
  2. Effect of dietary boron on mineral, estrogen, and testosterone metabolism in postmenopausal women.
    Nielsen FH; Hunt CD; Mullen LM; Hunt JR · FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 1987
    Single-arm trial12 participantsBone Health forBoron
  3. The relationship between boron and magnesium status and bone mineral density in the human: a review.
    Volpe SL; Taper LJ; Meacham S · Magnesium research · 1994
    Narrative reviewBone Health forBoron
  4. Effects of boron supplementation on bone mineral density and dietary, blood, and urinary calcium, phosphorus, magnesium, and boron in female athletes.
    Meacham SL; Taper LJ; Volpe SL · Environmental health perspectives · 1995
    Randomized trial28 participantsBone Health forBoron
  5. Metabolic responses of postmenopausal women to supplemental dietary boron and aluminum during usual and low magnesium intake: boron, calcium, and magnesium absorption and retention and blood mineral concentrations
    C D Hunt, J L Herbel, F H Nielsen · The American Journal of Clinical Nutrition · 1997
    Non-randomized trial11 participantsBone Health forBoron
  6. Risk of Environmental Chemicals on Bone Fractures Is Independent of Low Bone Mass in US Adults: Insights from 2017 to 2018 NHANES.
    Ling R; Ai Y; Chen C; Zhang J; Zou Z; Cheng S; Li C; Li X; Wang B · Metabolites · 2023
    Cross-sectional study2,640 participantsBone Health forManganese
  7. The Manganese-Bone Connection: Investigating the Role of Manganese in Bone Health.
    Taskozhina G; Batyrova G; Umarova G; Issanguzhina Z; Kereyeva N · Journal of clinical medicine · 2024
    Narrative reviewBone Health forManganese
  8. Associations of multiple metals with bone mineral density: A population-based study in US adults.
    Wei MH; Cui Y; Zhou HL; Song WJ; Di DS; Zhang RY; Huang Q; Liu JA; Wang Q · Chemosphere · 2021
    Cross-sectional studyBone Health forManganese
  9. Sex-specific associations of urinary mixed-metal concentrations with femoral bone mineral density among older people: an NHANES (2017-2020) analysis.
    Li H; Li G; Yi M; Zhou J; Deng Y; Huang Y; He S; Meng X; Liu L · Frontiers in public health · 2024
    Cross-sectional study31 participantsBone Health forManganese
  10. Relationship between blood manganese and bone mineral density and bone mineral content in adults: A population-based cross-sectional study.
    Wang C; Zhu Y; Long H; Ou M; Zhao S · PloS one · 2022
    Cross-sectional study9,732 participantsBone Health forManganese
  11. Can Dietary Intake of Vitamin C-Oriented Foods Reduce the Risk of Osteoporosis, Fracture, and BMD Loss? Systematic Review With Meta-Analyses of Recent Studies.
    Zeng LF; Luo MH; Liang GH; Yang WY; Xiao X; Wei X; Yu J; Guo D; Chen HY; Pan JK; Huang HT; Liu Q; Guan ZT; Han YH; Zhao D; Zhao JL; Hou SR; Wu M; Lin JT; Li JH; Liang WX; Ou AH; Wang Q; Li ZP; Liu J · Frontiers in endocrinology · 2020
    Meta-analysis19,484 participants17 studies pooledBone Health forVitamin C
  12. Dietary vitamin C intake and the risk of hip fracture: a dose-response meta-analysis.
    Sun Y; Liu C; Bo Y; You J; Zhu Y; Duan D; Cui H; Lu Q · Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2019
    Meta-analysis6 studies pooledBone Health forVitamin C
  13. Smoking, antioxidant vitamins, and the risk of hip fracture.
    Melhus H; Michaëlsson K; Holmberg L; Wolk A; Ljunghall S · Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research · 1999
    Cohort study66,651 participantsBone Health forVitamin C
  14. Micronutrients and the risk of hip fracture: Case-control study.
    Torbergsen AC; Watne LO; Wyller TB; Frihagen F; Strømsøe K; Bøhmer T; Mowe M · Clinical nutrition (Edinburgh, Scotland) · 2018
    Case-control study189 participantsBone Health forVitamin C
  15. Favorable effect of dietary vitamin C on bone mineral density in postmenopausal women (KNHANES IV, 2009): discrepancies regarding skeletal sites, age, and vitamin D status.
    Kim YA; Kim KM; Lim S; Choi SH; Moon JH; Kim JH; Kim SW; Jang HC; Shin CS · Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2016
    Cross-sectional study1,196 participantsBone Health forVitamin C
  16. Effects of boron supplementation on the severity and duration of pain in primary dysmenorrhea.
    Nikkhah S; Dolatian M; Naghii MR; Zaeri F; Taheri SM · Complementary therapies in clinical practice · 2015
    Randomized trial113 participantsEveryday Health forBoron
  17. Efficacy and safety of tavaborole topical solution, 5%, a novel boron-based antifungal agent, for the treatment of toenail onychomycosis: Results from 2 randomized phase-III studies.
    Elewski BE; Aly R; Baldwin SL; González Soto RF; Rich P; Weisfeld M; Wiltz H; Zane LT; Pollak R · Journal of the American Academy of Dermatology · 2015
    Randomized trialEveryday Health forBoron
  18. The efficacy and safety of tavaborole, a novel, boron-based pharmaceutical agent: phase 2 studies conducted for the topical treatment of toenail onychomycosis.
    Toledo-Bahena ME; Bucko A; Ocampo-Candiani J; Herz-Ruelas ME; Jones TM; Jarratt MT; Pollak RA; Zane LT · Journal of drugs in dermatology : JDD · 2015
    Clinical trial336 participantsEveryday Health forBoron
  19. Boron neutron capture therapy (BNCT) for glioblastoma multiforme: a phase II study evaluating a prolonged high-dose of boronophenylalanine (BPA).
    Henriksson R; Capala J; Michanek A; Lindahl SA; Salford LG; Franzén L; Blomquist E; Westlin JE; Bergenheim AT; Swedish Brain Tumour Study Group · Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology · 2009
    Single-arm trial30 participantsEveryday Health forBoron
  20. Effects of Calcium Fructoborate on Levels of C-Reactive Protein, Total Cholesterol, Low-Density Lipoprotein, Triglycerides, IL-1β, IL-6, and MCP-1: a Double-blind, Placebo-controlled Clinical Study
    Otilia-Constantina Rogoveanu, George Dan Mogosanu, Cornelia Bejenaru, Ludovic Everard Bejenaru, Octavian Croitoru, Johny Neamtu, Zbigniew Pietrzkowski, Tania Reyes-Izquierdo, Andrei Bita, Iulia Daria Scorei, Romulus Ion Scorei · Biological Trace Element Research · 2015
    Randomized trial78 participantsEveryday Health forBoron