Ester-C 500 mg With Citrus Bioflavoinds

Ester-C 500 mg With Citrus Bioflavoinds

American Health4.9 (2,773 ratings)
Format:Capsule Quantity: 60 Capsule(s) · 120 servings
Goals
$9.16 $0.07 per serving

Product analysis

68 out of 100

Ester-C 500 mg With Citrus Bioflavoinds supplies vitamin C for normal immune function and collagen formation. Undisclosed proportions in the added blend make its extra contribution harder to judge.

AI assessment of the formula, label and price. How scoring works

Nutrient Quality40

Calcium ascorbate identifies the vitamin C preparation, but does not establish better health outcomes. The added mixture also lacks enough support for a firm quality comparison.

Ingredient Transparency80

The main ingredient amounts and sources are stated. The added mixture does not disclose its component proportions.

Value For Money74

The vitamin C amount is economical for this type of preparation. Separate value for the calcium and added mixture cannot be established.

Customer Satisfaction91

Ratings indicate very high satisfaction from a sizable customer group. They do not describe specific effects or experiences.

Product Focus74

Vitamin C gives the formula a clear nutritional purpose. Its immune and skin connections mainly concern normal nutrient functions rather than added benefits when intake is adequate.

Format
Capsule
Container
60 Capsule(s)
Per serving
$0.07
Customer rating
4.9 · 2,773 ratings
Report analysis

Goals

Immunity
Impact
Highest effect
B Ingredient FitC PathwaysA+ EvidenceA+ Formulation Logic
Vitamin C · 1000 mg
Study evidence
Vitamin C Supportive 53 studies
Everyday Health
Impact
High effect
B Ingredient FitD+ PathwaysB- EvidenceA+ Formulation Logic
Vitamin C · 1000 mg
Study evidence
Vitamin C Supportive 56 studies
Impact
High effect
B- Ingredient FitD+ PathwaysA- EvidenceA+ Formulation Logic
Vitamin C · 1000 mg
Study evidence
Vitamin C Supportive 50 studies
Skin Health
Impact
High effect
B- Ingredient FitF PathwaysA+ EvidenceA+ Formulation Logic
Vitamin C · 1000 mg
Study evidence
Vitamin C Supportive 53 studies
Impact
High effect
B- Ingredient FitD PathwaysC+ EvidenceA+ Formulation Logic
Vitamin C · 1000 mg
Study evidence
Vitamin C Disputed 24 studies

Ingredients

IngredientAmount per servingScore
Vitamin C (Ester-C Calcium Ascorbate)
1000 mg 92
Calcium (Ester-C Calcium Ascorbate)
110 mg
Citrus Bioflavonoids Complex (Acerola, Hesperidin Complex, Lemon, Lime, Naturally Occuring Vitamin C Metabolites, Rutin, sweet Orange, Tangerine)
400 mg
Gluten Free Adults 18–50 Vegan Dairy Free Sugar Free Vegetarian
Report overview
A- Active Ingredient Quality & BioavailabilityA Dose, Safety & Label TransparencyA+ Value
Each serving provides 1000 mg of vitamin C at a low cost per gram. It uses buffered calcium ascorbate. The other-ingredient panel has no flagged sweeteners or artificial colors.
How this ingredient is rated

Active Ingredient Quality & Bioavailability90

Ester-C provides vitamin C as calcium ascorbate. Calcium ascorbate is a buffered mineral form, and the product is described as non-acidic.
Vitamin C Chemical Form & Delivery System
Ester-C provides vitamin C as calcium ascorbate.
Gastric Comfort & pH Balance
Calcium ascorbate is a buffered mineral form, and the product is described as non-acidic.

Dose, Safety & Label Transparency91

Each serving provides 1000 mg of vitamin C. The other-ingredient panel has no flagged sweeteners or artificial colors.
Optimal Dosage Targeting
Each serving provides 1000 mg of vitamin C.
Purity & Excipient Quality
The other-ingredient panel has no flagged sweeteners or artificial colors.
Mineral & Source Transparency
The label states 1000 mg vitamin C and 110 mg calcium.

Value100

The cost per gram of vitamin C is low.
Price per Gram of Vitamin C
The cost per gram of vitamin C is low.
Report alternatives

Sources

Published studies used for the product analysis and the top-ranked studies for each ingredient and goal.

  1. Dietary intake and blood concentrations of antioxidants and the risk of cardiovascular disease, total cancer, and all-cause mortality: a systematic review and dose-response meta-analysis of prospective studies.
    Aune D; Keum N; Giovannucci E; Fadnes LT; Boffetta P; Greenwood DC; Tonstad S; Vatten LJ; Riboli E; Norat T · The American journal of clinical nutrition · 2019
    Meta-analysis69 studies pooledEveryday Health forVitamin C
  2. Scientific Opinion on the substantiation of a health claim related to vitamin C and increasing non haem iron absorption pursuant to Article 14 of Regulation (EC) No 1924/2006.
    EFSA Panel on Dietetic Products, Nutrition and Allergies (NDA) · EFSA journal. European Food Safety Authority · 2026
    Guideline / consensusEveryday Health forVitamin C
  3. Vitamin C Depletion and All-Cause Mortality in Renal Transplant Recipients.
    Sotomayor CG; Eisenga MF; Gomes Neto AW; Ozyilmaz A; Gans ROB; Jong WHA; Zelle DM; Berger SP; Gaillard CAJM; Navis GJ; Bakker SJ · Nutrients · 2018
    Cohort study598 participantsEveryday Health forVitamin C
  4. Associations of Serum Biomarkers of Fruit and Vegetable Intake With the Risk of Cause-Specific Mortality and All-Cause Mortality: A National Prospective Cohort Study.
    Pu L; Zhang R; Wang X; Zhao T; Sun H; Han L · Frontiers in nutrition · 2022
    Cohort study12,530 participantsEveryday Health forVitamin C
  5. Relation between plasma ascorbic acid and mortality in men and women in EPIC-Norfolk prospective study: a prospective population study. European Prospective Investigation into Cancer and Nutrition.
    Khaw KT; Bingham S; Welch A; Luben R; Wareham N; Oakes S; Day N · Lancet (London, England) · 2001
    Cohort study19,496 participantsEveryday Health forVitamin C
  6. Role of Oral Vitamin 'C' on Astigmatic Errors in Phacoemulsification.
    Mohan S; Sah K; Khattri M; Ahmad L; Sachan SK · Current eye research · 2021
    Randomized trial400 participantsEye Health forVitamin C
  7. Ascorbic acid metabolites are involved in intraocular pressure control in the general population.
    Hysi PG; Khawaja AP; Menni C; Tamraz B; Wareham N; Khaw KT; Foster PJ; Benet LZ; Spector TD; Hammond CJ · Redox biology · 2019
    Observational studyEye Health forVitamin C
  8. Nutritional modulation of cataract.
    Weikel KA; Garber C; Baburins A; Taylor A · Nutrition reviews · 2014
    Narrative reviewEye Health forVitamin C
  9. Dietary n-3 Fatty Acid, α-Tocopherol, Zinc, vitamin D, vitamin C, and β-carotene are Associated with Age-Related Macular Degeneration in Japan.
    Aoki A; Inoue M; Nguyen E; Obata R; Kadonosono K; Shinkai S; Hashimoto H; Sasaki S; Yanagi Y · Scientific reports · 2017
    Case-control study530 participantsEye Health forVitamin C
  10. Adherence to a Mediterranean diet, lifestyle and age-related macular degeneration: the Coimbra Eye Study - report 3.
    Raimundo M; Mira F; Cachulo MDL; Barreto P; Ribeiro L; Farinha C; Laíns I; Nunes S; Alves D; Figueira J; Merle BM; Delcourt C; Santos L; Silva R · Acta ophthalmologica · 2019
    Case-control study883 participantsEye Health forVitamin C
  11. Vitamin C and contribution to the normal function of the immune system: evaluation of a health claim pursuant to Article 14 of Regulation (EC) No 1924/2006.
    EFSA Panel on Dietetic Products, Nutrition and Allergies (NDA) · EFSA journal. European Food Safety Authority · 2026
    Guideline / consensusImmunity forVitamin C
  12. Therapeutic effects of high-dose vitamin C supplementation in patients with COVID-19: a meta-analysis.
    Sun L; Zhao JH; Fan WY; Feng B; Liu WW; Chen RQ; Ban C; Dang AG; Wang M; Luo KT; Zhou GY; Yu FF; Ba Y · Nutrition reviews · 2024
    Meta-analysis2,334 participants14 studies pooledImmunity forVitamin C
  13. Effect of micronutrient supplements on influenza and other respiratory tract infections among adults: a systematic review and meta-analysis.
    Abioye AI; Bromage S; Fawzi W · BMJ global health · 2021
    Meta-analysisImmunity forVitamin C
  14. New evidence for antioxidant properties of vitamin C.
    Vojdani A; Bazargan M; Vojdani E; Wright J · Cancer detection and prevention · 2001
    Randomized trial20 participantsImmunity forVitamin C
  15. Enhanced Vitamin C Delivery: A Systematic Literature Review Assessing the Efficacy and Safety of Alternative Supplement Forms in Healthy Adults.
    Calder PC; Kreider RB; McKay DL · Nutrients · 2025
    Systematic review13 studies pooledImmunity forVitamin C
  16. Efficacy of Vitamin C as Glucocorticoid Substitute for Reducing Pain and Inflammation After Total Hip Arthroplasty: A Randomized Controlled Trial.
    Jiang W; Xu H; Jiang X; Zhan Y; Ju Y; Xie J; Huang Z; Huang Q; Pei F · The Journal of bone and joint surgery. American volume · 2025
    Randomized trial107 participantsInflammation forVitamin C
  17. The Impact of Vitamin C on Analgesic, Anti-inflammatory, and Hemostatic Outcomes After Total Hip and Knee Arthroplasty: A Systematic Review and Meta-Analysis.
    Moftakhari Hajimirzaei S; Bagherzadeh Cham M; Dolikhani M; Tabatabaee SM; Ebrahimpour A · The archives of bone and joint surgery · 2026
    Meta-analysis1,162 participants10 studies pooledInflammation forVitamin C
  18. The impact of vitamin C supplementation on the perioperative outcomes after total hip and knee arthroplasty: a systematic review and meta-analysis.
    Liu X; Guo J; Li Y; Yang Y; Liu M; Gao Q; Yang Y; Wu X; Yue C · BMC musculoskeletal disorders · 2026
    Meta-analysis852 participants8 studies pooledInflammation forVitamin C
  19. Therapeutic Impact of Ascorbic Acid on Oral and Periodontal Tissues: A Systematic Literature Review.
    Ruzijevaite G; Acaite E; Jagelaviciene E · Medicina (Kaunas, Lithuania) · 2025
    Systematic review811 participants17 studies pooledInflammation forVitamin C
  20. Oral vitamin C administration reduces early recurrence rates after electrical cardioversion of persistent atrial fibrillation and attenuates associated inflammation.
    Korantzopoulos P; Kolettis TM; Kountouris E; Dimitroula V; Karanikis P; Pappa E; Siogas K; Goudevenos JA · International journal of cardiology · 2005
    Randomized trial44 participantsInflammation forVitamin C