Ester-C 500 mg With Citrus Bioflavonoids

Ester-C 500 mg With Citrus Bioflavonoids

American Health4.9 (2,773 ratings)
Format:Capsule Quantity: 120 Capsule(s) · 60 servings
Goals
$15.39 $0.25 per serving

Product analysis

68 out of 100

Ester-C 500 mg With Citrus Bioflavonoids offers good value for supporting normal immune nutrition and collagen formation when vitamin C intake is low.

AI assessment of the formula, label and price. How scoring works

Nutrient Quality37

The vitamin C and calcium forms are identified, while their form quality remains uncertain. The citrus flavonoid mixture also lacks a clear form, making that addition harder to compare.

Ingredient Transparency88

Amounts are disclosed for the listed ingredients, and the main vitamin C form is clear. The flavonoid mixture is less precisely identified.

Value For Money74

The vitamin C contribution offers very good value. Value for the calcium and flavonoid additions remains uncertain, so the main buying case rests on vitamin C.

Customer Satisfaction91

Customer feedback is very positive across several thousand ratings. The substantial review base gives useful confidence in satisfaction, without proving health effects.

Product Focus74

Vitamin C provides the clearest nutritional purpose through normal immune function and collagen formation. The additional ingredients do not establish stronger benefits when nutrient needs are already met.

Format
Capsule
Container
120 Capsule(s)
Per serving
$0.25
Customer rating
4.9 · 2,773 ratings
Report analysis

Goals

Everyday Health
Impact
High effect
B Ingredient FitD+ PathwaysB- EvidenceA+ Formulation Logic
Vitamin C · 1000 mg
Study evidence
Vitamin C Supportive 56 studies
Immunity
Impact
Highest effect
B Ingredient FitC PathwaysA+ EvidenceA+ Formulation Logic
Vitamin C · 1000 mg
Study evidence
Vitamin C Supportive 53 studies
Skin Health
Impact
High effect
B- Ingredient FitF PathwaysA+ EvidenceA+ Formulation Logic
Vitamin C · 1000 mg
Study evidence
Vitamin C Supportive 53 studies
Impact
High effect
B- Ingredient FitD+ PathwaysA- EvidenceA+ Formulation Logic
Vitamin C · 1000 mg
Study evidence
Vitamin C Supportive 50 studies
Impact
High effect
B- Ingredient FitD PathwaysC+ EvidenceA+ Formulation Logic
Vitamin C · 1000 mg
Study evidence
Vitamin C Disputed 24 studies

Ingredients

IngredientAmount per servingScore
Vitamin C (Ester-C Calcium Ascorbate)
1000 mg 92
Calcium (Ester-C Calcium Ascorbate)
110 mg
Citrus Bioflavonoids Complex
400 mg
Gluten Free Adults 18–50 Vegan Dairy Free Sugar Free Vegetarian
Report overview
A- Active Ingredient Quality & BioavailabilityA Dose, Safety & Label TransparencyA+ Value
Each serving provides 1000 mg of vitamin C. The cost per gram of vitamin C is low. Ester-C supplies vitamin C as calcium ascorbate with metabolites.
How this ingredient is rated

Active Ingredient Quality & Bioavailability90

Ester-C supplies vitamin C as calcium ascorbate with metabolites. Ester-C uses buffered calcium ascorbate.
Vitamin C Chemical Form & Delivery System
Ester-C supplies vitamin C as calcium ascorbate with metabolites.
Gastric Comfort & pH Balance
Ester-C uses buffered calcium ascorbate.

Dose, Safety & Label Transparency91

Each serving provides 1000 mg of vitamin C. The vitamin C and calcium amounts are stated.
Optimal Dosage Targeting
Each serving provides 1000 mg of vitamin C.
Purity & Excipient Quality
The other-ingredient panel has no flagged sweeteners, artificial colors or preservatives.
Mineral & Source Transparency
The vitamin C and calcium amounts are stated.

Value100

The cost per gram of vitamin C is low.
Price per Gram of Vitamin C
The cost per gram of vitamin C is low.
Report alternatives

Sources

Published studies used for the product analysis and the top-ranked studies for each ingredient and goal.

  1. Dietary intake and blood concentrations of antioxidants and the risk of cardiovascular disease, total cancer, and all-cause mortality: a systematic review and dose-response meta-analysis of prospective studies.
    Aune D; Keum N; Giovannucci E; Fadnes LT; Boffetta P; Greenwood DC; Tonstad S; Vatten LJ; Riboli E; Norat T · The American journal of clinical nutrition · 2019
    Meta-analysis69 studies pooledEveryday Health forVitamin C
  2. Scientific Opinion on the substantiation of a health claim related to vitamin C and increasing non haem iron absorption pursuant to Article 14 of Regulation (EC) No 1924/2006.
    EFSA Panel on Dietetic Products, Nutrition and Allergies (NDA) · EFSA journal. European Food Safety Authority · 2026
    Guideline / consensusEveryday Health forVitamin C
  3. Vitamin C Depletion and All-Cause Mortality in Renal Transplant Recipients.
    Sotomayor CG; Eisenga MF; Gomes Neto AW; Ozyilmaz A; Gans ROB; Jong WHA; Zelle DM; Berger SP; Gaillard CAJM; Navis GJ; Bakker SJ · Nutrients · 2018
    Cohort study598 participantsEveryday Health forVitamin C
  4. Associations of Serum Biomarkers of Fruit and Vegetable Intake With the Risk of Cause-Specific Mortality and All-Cause Mortality: A National Prospective Cohort Study.
    Pu L; Zhang R; Wang X; Zhao T; Sun H; Han L · Frontiers in nutrition · 2022
    Cohort study12,530 participantsEveryday Health forVitamin C
  5. Relation between plasma ascorbic acid and mortality in men and women in EPIC-Norfolk prospective study: a prospective population study. European Prospective Investigation into Cancer and Nutrition.
    Khaw KT; Bingham S; Welch A; Luben R; Wareham N; Oakes S; Day N · Lancet (London, England) · 2001
    Cohort study19,496 participantsEveryday Health forVitamin C
  6. Role of Oral Vitamin 'C' on Astigmatic Errors in Phacoemulsification.
    Mohan S; Sah K; Khattri M; Ahmad L; Sachan SK · Current eye research · 2021
    Randomized trial400 participantsEye Health forVitamin C
  7. Ascorbic acid metabolites are involved in intraocular pressure control in the general population.
    Hysi PG; Khawaja AP; Menni C; Tamraz B; Wareham N; Khaw KT; Foster PJ; Benet LZ; Spector TD; Hammond CJ · Redox biology · 2019
    Observational studyEye Health forVitamin C
  8. Nutritional modulation of cataract.
    Weikel KA; Garber C; Baburins A; Taylor A · Nutrition reviews · 2014
    Narrative reviewEye Health forVitamin C
  9. Dietary n-3 Fatty Acid, α-Tocopherol, Zinc, vitamin D, vitamin C, and β-carotene are Associated with Age-Related Macular Degeneration in Japan.
    Aoki A; Inoue M; Nguyen E; Obata R; Kadonosono K; Shinkai S; Hashimoto H; Sasaki S; Yanagi Y · Scientific reports · 2017
    Case-control study530 participantsEye Health forVitamin C
  10. Adherence to a Mediterranean diet, lifestyle and age-related macular degeneration: the Coimbra Eye Study - report 3.
    Raimundo M; Mira F; Cachulo MDL; Barreto P; Ribeiro L; Farinha C; Laíns I; Nunes S; Alves D; Figueira J; Merle BM; Delcourt C; Santos L; Silva R · Acta ophthalmologica · 2019
    Case-control study883 participantsEye Health forVitamin C
  11. Vitamin C and contribution to the normal function of the immune system: evaluation of a health claim pursuant to Article 14 of Regulation (EC) No 1924/2006.
    EFSA Panel on Dietetic Products, Nutrition and Allergies (NDA) · EFSA journal. European Food Safety Authority · 2026
    Guideline / consensusImmunity forVitamin C
  12. Therapeutic effects of high-dose vitamin C supplementation in patients with COVID-19: a meta-analysis.
    Sun L; Zhao JH; Fan WY; Feng B; Liu WW; Chen RQ; Ban C; Dang AG; Wang M; Luo KT; Zhou GY; Yu FF; Ba Y · Nutrition reviews · 2024
    Meta-analysis2,334 participants14 studies pooledImmunity forVitamin C
  13. Effect of micronutrient supplements on influenza and other respiratory tract infections among adults: a systematic review and meta-analysis.
    Abioye AI; Bromage S; Fawzi W · BMJ global health · 2021
    Meta-analysisImmunity forVitamin C
  14. New evidence for antioxidant properties of vitamin C.
    Vojdani A; Bazargan M; Vojdani E; Wright J · Cancer detection and prevention · 2001
    Randomized trial20 participantsImmunity forVitamin C
  15. Enhanced Vitamin C Delivery: A Systematic Literature Review Assessing the Efficacy and Safety of Alternative Supplement Forms in Healthy Adults.
    Calder PC; Kreider RB; McKay DL · Nutrients · 2025
    Systematic review13 studies pooledImmunity forVitamin C
  16. Efficacy of Vitamin C as Glucocorticoid Substitute for Reducing Pain and Inflammation After Total Hip Arthroplasty: A Randomized Controlled Trial.
    Jiang W; Xu H; Jiang X; Zhan Y; Ju Y; Xie J; Huang Z; Huang Q; Pei F · The Journal of bone and joint surgery. American volume · 2025
    Randomized trial107 participantsInflammation forVitamin C
  17. The Impact of Vitamin C on Analgesic, Anti-inflammatory, and Hemostatic Outcomes After Total Hip and Knee Arthroplasty: A Systematic Review and Meta-Analysis.
    Moftakhari Hajimirzaei S; Bagherzadeh Cham M; Dolikhani M; Tabatabaee SM; Ebrahimpour A · The archives of bone and joint surgery · 2026
    Meta-analysis1,162 participants10 studies pooledInflammation forVitamin C
  18. The impact of vitamin C supplementation on the perioperative outcomes after total hip and knee arthroplasty: a systematic review and meta-analysis.
    Liu X; Guo J; Li Y; Yang Y; Liu M; Gao Q; Yang Y; Wu X; Yue C · BMC musculoskeletal disorders · 2026
    Meta-analysis852 participants8 studies pooledInflammation forVitamin C
  19. Therapeutic Impact of Ascorbic Acid on Oral and Periodontal Tissues: A Systematic Literature Review.
    Ruzijevaite G; Acaite E; Jagelaviciene E · Medicina (Kaunas, Lithuania) · 2025
    Systematic review811 participants17 studies pooledInflammation forVitamin C
  20. Oral vitamin C administration reduces early recurrence rates after electrical cardioversion of persistent atrial fibrillation and attenuates associated inflammation.
    Korantzopoulos P; Kolettis TM; Kountouris E; Dimitroula V; Karanikis P; Pappa E; Siogas K; Goudevenos JA · International journal of cardiology · 2005
    Randomized trial44 participantsInflammation forVitamin C