Product Image

High-Performance Pre-Workout Black Cherry

Pre JYM
4.6
★ ★ ★ ★ ★
(3860 ratings)
Huperzine 50 mcg
Caffeine 300 mg
Alpha-GPC 150 mg
Product Image
Score71
A broadly dosed pre-workout with meaningful performance and focus ingredients. The Alpha-GPC amount and active yield are modest is the key trade-off alongside a premium serving cost.
How scoring works
Quantity:27 Ounce(s) • (30 servings)
Goals:
Fitness
Energy
Productivity Boost
Muscle Gain
Metabolism Boost
Mental Focus
Weight Loss
Cognitive Support
Brain Health

Score 71

A broadly dosed pre-workout with meaningful performance and focus ingredients. The Alpha-GPC amount and active yield are modest is the key trade-off alongside a premium serving cost.
How scoring works
$53.99($1.79 per serving)
iHerb
$ 53.99
Amazon
$ 53.99
Report prices

Analysis

Citrulline malate, creatine HCl, beta-alanine, betaine, taurine, amino acids, tyrosine, and 300 mg caffeine covers pump, training capacity, and energy in one serving. AlphaSize and Huperzine A add a disclosed focus stack adds a cognitive component, though stimulant effects will drive much of the immediate experience.

The formula fits energy, fitness, muscle, and productivity goals better than broad brain health. Strong dosing may suit experienced pre-workout users but can be excessive for stimulant-sensitive people.

Most important actives have stated amounts, supporting direct comparison. The Alpha-GPC amount and active yield are modest remains the main transparency problem, while a premium serving cost weakens practical value.

Who is it for
  • Experienced adults seeking a high-stimulant pre-workout
  • Users wanting pump, training, and focus support together
  • People who can avoid other caffeine sources
Best for
  • Workout energy
  • Training performance
  • Short-term mental focus

Pros

  • Covers several performance pathways
  • AlphaSize and Huperzine A add a disclosed focus stack
  • Discloses the main stimulant amount

Cons

  • The Alpha-GPC amount and active yield are modest
  • a premium serving cost
  • Not suited to caffeine-sensitive users

Warnings

  • The 300 mg caffeine can cause jitteriness, rapid heartbeat, anxiety, or sleep disruption, especially with other stimulants.
  • Beta-alanine commonly causes harmless tingling, while the stimulant load may be harder to tolerate.
  • BioPerine can alter exposure to some medicines by changing their absorption or metabolism.

Nutrient quality

79 High impact

Broad, fully measured performance ingredients provide strong workout, energy, and focus support. Several actives fall below common full amounts, and the strong stimulant-cholinergic stack needs caution.

.

Ingredient transparency

79 High impact

All active amounts are visible and no proprietary blend is used. Complete safety directions, cycling guidance, and inactive flavor-system details remain unavailable.

.

Customer satisfaction

68 High impact

The supplied aggregate satisfaction signal is favorable and has some support from its response volume. Specific experience details are absent, so complaint patterns and purpose fit cannot be confirmed.

.

Value for money

53 Moderate impact

The core fully disclosed pre-workout provides real functional value. Premium serving positioning and uneven dose depth make the product less competitive.

.
Report analysis

Goals

Fitness
Fitness
Impact
Highest effect
A+ Goal FitA Strength of SupportA CoverageA Formula Quality
Creatine · 2 Gram(s)Beta-Alanine · 2 Gram(s)Caffeine · 300 mg

Citrulline, creatine, beta-alanine, betaine, taurine, branched-chain amino acids, and caffeine cover many major pre-workout needs. Most active amounts are fully disclosed, including a substantial citrulline serving and a strong caffeine load.

The 300 mg caffeine amount may cause jitters, rapid heartbeat, or sleep disruption, while 10 mg sodium provides limited hydration support. Beta-alanine and creatine are somewhat modest, but the formula remains broad and performance-focused.

Study evidence
Caffeine Supportive 255 studies
Creatine Supportive 143 studies
Sodium Supportive 96 studies
Taurine Supportive 21 studies
Energy
Energy
Impact
Highest effect
A+ Goal FitA Strength of SupportA CoverageB+ Formula Quality
Potassium · 77 mgCaffeine · 300 mgCreatine · 2 Gram(s)

Caffeine, tyrosine, creatine, citrulline, beta-alanine, and betaine create a potent acute energy and performance formula. The 300 mg caffeine amount provides strong alertness but may feel intense for caffeine-sensitive users.

Most performance ingredients are individually disclosed at meaningful amounts, although some sit below common full standalone servings. Combining the serving with other caffeine sources may increase insomnia, anxiety, rapid heartbeat, or blood pressure effects.

Study evidence
Caffeine Supportive 68 studies
Creatine Supportive 49 studies
Productivity Boost
Productivity Boost
Impact
Highest effect
A Goal FitA Strength of SupportA- CoverageC+ Formula Quality
Creatine · 2 Gram(s)Huperzine · 50 mcgAlpha-GPC · 150 mgCaffeine · 300 mg

Caffeine, L-tyrosine, Alpha-GPC, and Huperzine A create a strong acute focus and mental-performance stack. The formula is designed for workouts, yet its main cognitive actives are more substantial than those in many general productivity products.

Most doses are fully disclosed, with branded AlphaSize adding source quality even though its active Alpha-GPC yield is not stated. The 300 mg caffeine amount may cause jitteriness, a rapid heartbeat, or sleep disruption, especially alongside other stimulants.

Study evidence
Alpha-GPC Supportive 2 studies
Caffeine Supportive 108 studies
Huperzine No effect 1 study
Muscle Gain
Muscle Gain
Impact
Highest effect
A- Goal FitB Strength of SupportB+ CoverageB+ Formula Quality
Creatine · 2 Gram(s)Caffeine · 300 mgBeta-Alanine · 2 Gram(s)

Creatine HCl, citrulline malate, beta-alanine, betaine, and caffeine create broad support for strength-focused training and workout volume. Leucine and the other branched-chain amino acids may add little when complete protein intake is already sufficient.

Several actives are below common standalone targets, but their combined effects still form a substantial pre-workout stack. The strong caffeine amount may cause jitters or disrupt sleep in sensitive users, which can interfere with recovery.

Study evidence
Alpha-GPC Not classified 1 study
Caffeine Supportive 31 studies
Creatine Supportive 136 studies
Metabolism Boost
Metabolism Boost
Impact
Highest effect
B+ Goal FitA Strength of SupportB CoverageB- Formula Quality
Creatine · 2 Gram(s)Caffeine · 300 mg

Caffeine directly raises short-term energy expenditure, while tyrosine and exercise-performance ingredients support active energy use. Human evidence strongly supports caffeine for thermogenesis, while the other ingredients mainly improve training performance rather than resting metabolism.

The 300 mg caffeine amount is potent, and citrulline, tyrosine, taurine, betaine, and creatine are supplied at meaningful performance doses. All major amounts and forms are disclosed, including pure caffeine anhydrous and branded creatine. The 300 mg caffeine amount may cause jitteriness, sleep disruption, or a rapid heartbeat and should not be stacked with other stimulants.

Study evidence
Caffeine Disputed 40 studies
Creatine Supportive 21 studies
Taurine Supportive 11 studies
Mental Focus
Mental Focus
Impact
Highest effect
A Goal FitA- Strength of SupportB+ CoverageC Formula Quality
Alpha-GPC · 150 mgCreatine · 2 Gram(s)Caffeine · 300 mgHuperzine · 50 mcg

Caffeine, L-tyrosine, Alpha-GPC, and Huperzine A create a direct and broad acute-focus profile. Caffeine has strong attention evidence, while the cholinergic ingredients add plausible support with less certainty for healthy users.

The caffeine, tyrosine, and Huperzine A amounts are useful, but the Alpha-GPC listing does not state active yield and is likely modest. The 300 mg caffeine serving may cause jitteriness, sleep disruption, or a rapid heartbeat, especially when combined with other stimulants.

Study evidence
Alpha-GPC Supportive 1 study
Caffeine Supportive 128 studies
Huperzine Not classified

No linked studies yet.

Ingredients

IngredientAmount per serving
Calories
80 Calorie(s)
Sodium
10 mg
Total Carbohydrates
3 Gram(s)
Calcium
53 mg
Potassium
77 mg
CON-CRET Creatine HCl
2 Gram(s)
Beta-Alanine
2 Gram(s)
Betaine
1.5 Gram(s)
Taurine
1 Gram(s)
AlphaSize (Alpha-Glycerylphosphorylcholine)
 150 mg
Citrulline Malate
6 Gram(s)
Beet root extract
500 mg
L-Leucine
3 Gram(s)
L-Isoleucine
1.5 Gram(s)
L-Valine
1.5 Gram(s)
L-Tyrosine
1.5 Gram(s)
Caffeine Anhydrous
300 mg
Huperzine A (Toothed Clubmoss aerial parts extract)
 50 mcg
BioPerine (Black Pepper Fruit Extract)
 5 mg
Adults 18–50 Women
Report overview
Huperzine (Toothed Clubmoss aerial parts extract) · 50 mcg OverallScore80
B Active Ingredient Quality & BioavailabilityA- Dose, Safety & Label TransparencyB Value

The disclosed Huperzine A amount falls in the useful range and comes from a named Toothed Clubmoss extract. The large multi-ingredient powder is less precise than a pre-measured capsule or tablet, although Alpha-GPC adds relevant formula value. Each serving also supplies 300 mg of caffeine, so combining it with other stimulants could increase jitteriness, sleep disruption, or a rapid heartbeat.

View ingredientView products
Caffeine · 300 mg OverallScore69
B Active Ingredient Quality & BioavailabilityA Dose, Safety & Label TransparencyF Value

Caffeine anhydrous provides a pure, well-characterized source at a strong amount for performance. The immediate-release formula lacks a sustained component, and the dose may feel intense for caffeine-sensitive users. Its broad pre-workout profile is fully disclosed, but the serving cost is very high.

View ingredientView products
Alpha-GPC (Alpha-Glycerylphosphorylcholine) · 150 mg OverallScore50
C+ Active Ingredient Quality & BioavailabilityF Dose, Safety & Label TransparencyD- Value

Branded AlphaSize supports ingredient quality, but the loose powder format leaves moisture stability poorly protected. The listed 150 mg amount does not state active yield, so the assumed active dose is low and its active-normalized value is weak. The 300 mg caffeine dose may cause jitters, sleep disruption, or a rapid heartbeat in caffeine-sensitive users.

View ingredientView products
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<p>A deeper performance formula combines citrulline malate, beta-alanine, betaine, Alpha-GPC, theanine, and caffeine at disclosed amounts. It provides stronger pump, endurance, and focus coverage than the original, although the high caffeine amount may not suit stimulant-sensitive users.</p>
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High-Performance Pre-Workout Pineapple Strawberry

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<p>A broad, fully disclosed formula adds citrulline malate, creatine HCl, beta-alanine, betaine, taurine, branched-chain amino acids, tyrosine, Alpha-GPC, caffeine, and huperzine. It covers more aspects of workout performance and focus than the original, though its caffeine amount remains high.</p>
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<p>A focused cognitive blend supplies Alpha-GPC, acetyl-L-carnitine, lion’s mane, tyrosine, phosphatidylserine, caffeine, and methyliberine. It is a better choice when mental focus is the priority, but it does not replace the original’s pump or muscular-performance ingredients.</p>
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<p>A much lower serving cost comes with caffeine, choline, green coffee extract, alpha-lipoic acid, and huperzine for energy and metabolism support. It lacks the original-style citrulline, beta-alanine, and creatine foundation, so it is a better budget fit when stimulation matters more than complete workout support.</p>
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Seventh Gear Your Mom's Lemonade

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<p>A lower serving cost retains beta-alanine, betaine, creatine, Alpha-GPC, huperzine, and several stimulant forms. The performance ingredients are modestly dosed, but the formula keeps useful energy and focus coverage while improving cost efficiency.</p>
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High-Performance Pre-Workout Rainbow Sherbet

Pre JYM
<p>The lower serving cost includes disclosed citrulline malate, creatine HCl, beta-alanine, betaine, taurine, amino acids, tyrosine, Alpha-GPC, caffeine, and huperzine. That broad formula supports training, energy, and focus without giving up the main functions of the original.</p>
78 Value

High-Performance Pre-Workout Tangerine

Pre JYM
<p>A lower serving cost buys a fully disclosed mix of citrulline malate, creatine HCl, beta-alanine, betaine, taurine, amino acids, tyrosine, Alpha-GPC, caffeine, and huperzine. The broad training and focus coverage makes it a stronger value than the original, with high caffeine as the main caution.</p>
66 Value

Bucked Up Pre-Workout 'Merica Rocket Pop

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<p>A lower serving cost still provides citrulline malate, beta-alanine, caffeine, Alpha-GPC, and taurine in a disclosed formula. Citrulline supports its value for pump-focused training, while the lighter beta-alanine and Alpha-GPC amounts are meaningful trade-offs.</p>
66 Value

Pre-Workout Blood Raz

Bucked Up
<p>A more economical serving retains citrulline malate, beta-alanine, caffeine, Alpha-GPC, and taurine for pump, energy, and focus. The formula is less comprehensive than the strongest candidates, but its disclosed core ingredients make it a practical value alternative to the original.</p>
Report alternatives

Sources

Published studies used for the product analysis and the top-ranked studies for each ingredient and goal.

  1. Differential cognitive effects of energy drink ingredients: caffeine, taurine, and glucose.
    Giles GE; Mahoney CR; Brunyé TT; Gardony AL; Taylor HA; Kanarek RB · Pharmacology, biochemistry, and behavior · 2013
    Randomized trial48 participantsEnergy forCaffeine
  2. A critical review of caffeine withdrawal: empirical validation of symptoms and signs, incidence, severity, and associated features.
    Juliano LM; Griffiths RR · Psychopharmacology · 2005
    Systematic review66 studies pooledEnergy forCaffeine
  3. Effect of caffeine ingestion on cycling performance: a systematic review and meta-analysis.
    Wu J; Xu K; Yin M; Ding X; Wang T; Zhang Q; Wu X; Xiao N · Frontiers in nutrition · 2026
    Meta-analysis226 participants20 studies pooledFitness forCaffeine
  4. Acute Effects of Caffeine Supplementation on Physical Performance, Physiological Responses, Perceived Exertion, and Technical-Tactical Skills in Combat Sports: A Systematic Review and Meta-Analysis.
    Delleli S; Ouergui I; Messaoudi H; Trabelsi K; Ammar A; Glenn JM; Chtourou H · Nutrients · 2022
    Meta-analysis26 studies pooledFitness forCaffeine
  5. Cognitive improvement in mild to moderate Alzheimer's dementia after treatment with the acetylcholine precursor choline alfoscerate: a multicenter, double-blind, randomized, placebo-controlled trial.
    De Jesus Moreno Moreno M · Clinical therapeutics · 2003
    Randomized trial261 participantsBrain Health forAlpha-GPC
  6. [Clinical efficacy and safety of huperzine Alpha in treatment of mild to moderate Alzheimer disease, a placebo-controlled, double-blind, randomized trial].
    Zhang Z; Wang X; Chen Q; Shu L; Wang J; Shan G · Zhonghua yi xue za zhi · 2002
    Randomized trial202 participantsBrain Health Cognitive Support forHuperzine
  7. Effect of Huperzine A on Cognitive Function and Perception of Effort during Exercise: A Randomized Double-Blind Crossover Trial.
    Wessinger CM; Inman CL; Weinstock J; Weiss EP · International journal of exercise science · 2025
    Randomized trial15 participantsBrain Health Productivity Boost forHuperzine
  8. Activity of Choline Alphoscerate on Adult-Onset Cognitive Dysfunctions: A Systematic Review and Meta-Analysis.
    Sagaro GG; Traini E; Amenta F · Journal of Alzheimer's disease : JAD · 2023
    Meta-analysis8 studies pooledCognitive Support Brain Health forAlpha-GPC
  9. Effect of Choline Alfoscerate on the Progression From Mild Cognitive Impairment to Dementia: Distributed Network Analysis of a Multicenter Korean Database Using a Common Data Model.
    Pyun JM; Lee I; Lee K; Kim MH; Park C; Yang HJ · Dementia and neurocognitive disorders · 2024
    Cohort study3,062 participantsCognitive Support forAlpha-GPC
  10. Huperzine a in the treatment of Alzheimer's disease and vascular dementia: a meta-analysis.
    Xing SH; Zhu CX; Zhang R; An L · Evidence-based complementary and alternative medicine : eCAM · 2014
    Meta-analysis825 participants10 studies pooledCognitive Support Brain Health forHuperzine
  11. Huperzine A for vascular dementia.
    Hao Z; Liu M; Liu Z; Lv D · The Cochrane database of systematic reviews · 2009
    Systematic review14 participants1 studies pooledCognitive Support forHuperzine
  12. Comparative study of choline alfoscerate as a combination therapy with donepezil: A mixed double-blind randomized controlled and open-label observation trial.
    Lee W; Kim M · Medicine · 2024
    Randomized trial119 participantsBrain Health Cognitive Support forAlpha-GPC
  13. Effects of choline alfoscerate on cognitive function and quality of life in type 2 diabetes: A double-blind, randomized, placebo-controlled trial.
    Sohn M; Park YH; Lim S · Diabetes, obesity & metabolism · 2025
    Randomized trial36 participantsBrain Health Cognitive Support forAlpha-GPC
  14. Acute Alpha-Glycerylphosphorylcholine Supplementation Enhances Cognitive Performance in Healthy Men.
    Kerksick CM · Nutrients · 2024
    Randomized trial20 participantsBrain Health Mental Focus Productivity Boost forAlpha-GPC
  15. Oral creatine monohydrate supplementation improves brain performance: a double-blind, placebo-controlled, cross-over trial.
    Rae C; Digney AL; McEwan SR; Bates TC · Proceedings. Biological sciences · 2003
    Randomized trial45 participantsBrain Health forCreatine
  16. Creatine in Huntington disease is safe, tolerable, bioavailable in brain and reduces serum 8OH2'dG.
    Hersch SM; Gevorkian S; Marder K; Moskowitz C; Feigin A; Cox M; Como P; Zimmerman C; Lin M; Zhang L; Ulug AM; Beal MF; Matson W; Bogdanov M; Ebbel E; Zaleta A; Kaneko Y; Jenkins B; Hevelone N; Zhang H; Yu H; Schoenfeld D; Ferrante R; Rosas HD · Neurology · 2006
    Randomized trial64 participantsBrain Health forCreatine
  17. Creatine supplementation and cognitive performance in elderly individuals.
    McMorris T; Mielcarz G; Harris RC; Swain JP; Howard A · Neuropsychology, development, and cognition. Section B, Aging, neuropsychology and cognition · 2008
    Randomized trial32 participantsBrain Health forCreatine
  18. Effects of high-load, velocity-intentional variable resistance training combined with creatine supplementation on neuroplasticity, oxidative stress, inflammation, physical function, cognitive performance and quality of life in older adults: A randomized, double-blind, placebo-controlled trial.
    Fernandez-Garrido J; Martin EG; Saez-Berlanga A; Gargallo-Bayo P; Gene-Morales J; Alix-Fages C; Jiménez-Martínez P; Caballero O; Salvador-Palmer R; Colado JC · Experimental gerontology · 2026
    Randomized trial103 participantsBrain Health forCreatine
  19. Single-Dose Creatine Reduces Sleep Deprivation-Induced Deterioration in Cognitive Performance.
    Gordji-Nejad A; Matusch A; Hengstler L; Beer S; Kroll T; Klein S; Elmenhorst D; Bauer A; Drzezga A · Nutrients · 2026
    Randomized trial29 participantsBrain Health forCreatine
  20. Huperzine A associated with improved early postoperative cognitive function after neurosurgery under general anesthesia: a randomized clinical trial.
    Zhang Z; Shen Y; Li J; Tang Y; Zhou P; Ying T; Mo R; Ru Z; Zhao G; Zhu J; Li S; Zhao H · International journal of surgery (London, England) · 2026
    Randomized trial123 participantsBrain Health Cognitive Support forHuperzine
  21. Treatment with Huperzine A improves cognition in vascular dementia patients.
    Xu ZQ; Liang XM; Juan-Wu; Zhang YF; Zhu CX; Jiang XJ · Cell biochemistry and biophysics · 2012
    Randomized trial78 participantsBrain Health forHuperzine
  22. Huperzine-A response to cognitive impairment and task switching deficits in patients with Alzheimer's disease.
    Gul A; Bakht J; Mehmood F · Journal of the Chinese Medical Association : JCMA · 2019
    Randomized trial100 participantsBrain Health forHuperzine
  23. Combined L-carnosine and L-tyrosine supplementation as an ergogenic strategy for physical and cognitive performance under fatigue in professional football players.
    Bilgin S; Bozyılan E; Buzdağlı Y; Karaç Öcal Y; Gürkan O; Toktaş S; İnan H; Egil İ; Yarayan YE · Frontiers in nutrition · 2026
    Randomized trial24 participantsBrain Health forTyrosine
  24. Effect of tyrosine supplementation on clinical and healthy populations under stress or cognitive demands--A review.
    Jongkees BJ; Hommel B; Kühn S; Colzato LS · Journal of psychiatric research · 2016
    Narrative reviewBrain Health forTyrosine
  25. Influence of nutritional tyrosine on cognition and functional connectivity in healthy old humans.
    Hensel C; Becker M; Düzel S; Demuth I; Norman K; Steinhagen-Thiessen E; Gallinat J; Lindenberger U; Kühn S · NeuroImage · 2019
    Cross-sectional study286 participantsBrain Health forTyrosine
  26. Dietary Tyrosine Intake (FFQ) Is Associated with Locus Coeruleus, Attention and Grey Matter Maintenance: An MRI Structural Study on 398 Healthy Individuals of the Berlin Aging Study-II.
    Plini ERG; Melnychuk MC; Harkin A; Dahl MJ; McAuslan M; Kühn S; Boyle RT; Whelan R; Andrews R; Düzel S; Drewelies J; Wagner GG; Lindenberger U; Norman K; Robertson IH; Dockree PM · The journal of nutrition, health & aging · 2023
    Cross-sectional study398 participantsBrain Health forTyrosine
  27. Baseline-dependent effect of dopamine's precursor L-tyrosine on working memory gating but not updating.
    Jongkees BJ · Cognitive, affective & behavioral neuroscience · 2021
    Randomized trial45 participantsBrain Health forTyrosine
  28. [Gliatilin in the Treatment of Cognitive Impairments Not Reaching the Level of Dementia: Meta-Analysis and Systematic Review].
    Voznyuk IA; Nepomnyashchiy IS; Kutkova AK; Tokareva DV; Prokhorova MV; Ovdiienko OA; Shusharina NN · Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova · 2025
    Meta-analysis10 studies pooledCognitive Support forAlpha-GPC
  29. Vertical Association Between Dietary Total Choline and L-alpha-glycerylphosphorylcholine and the Cognitive Function in Chinese Adults Aged over 55, Result from China Health and Nutrition Survey 1997-2018.
    Guan F; Jia X; Huang F; Zhang J; Wei Y; Li L; Bai J; Wang H · Nutrients · 2024
    Cohort study7,659 participantsCognitive Support forAlpha-GPC
  30. Adjunctive huperzine A for cognitive deficits in schizophrenia: a systematic review and meta-analysis.
    Zheng W; Xiang YQ; Li XB; Ungvari GS; Chiu HF; Sun F; D'Arcy C; Meng X; Xiang YT · Human psychopharmacology · 2017
    Meta-analysis1,117 participants12 studies pooledCognitive Support forHuperzine
  31. [Drug evaluation of huperzine A in the treatment of senile memory disorders].
    Zhang RW; Tang XC; Han YY; Sang GW; Zhang YD; Ma YX; Zhang CL; Yang RM · Zhongguo yao li xue bao = Acta pharmacologica Sinica · 1992
    Randomized trial56 participantsCognitive Support forHuperzine
  32. Cognitive and mood improvements of caffeine in habitual consumers and habitual non-consumers of caffeine.
    Haskell CF; Kennedy DO; Wesnes KA; Scholey AB · Psychopharmacology · 2005
    Randomized trial48 participantsEnergy forCaffeine
  33. Caffeine-containing energy drink improves physical performance of elite rugby players during a simulated match.
    Del Coso J; Ramírez JA; Muñoz G; Portillo J; Gonzalez-Millán C; Muñoz V; Barbero-Álvarez JC; Muñoz-Guerra J · Applied physiology, nutrition, and metabolism = Physiologie appliquee, nutrition et metabolisme · 2016
    Randomized trial26 participantsEnergy forCaffeine
  34. Does Single or Combined Caffeine and Taurine Supplementation Improve Athletic and Cognitive Performance without Affecting Fatigue Level in Elite Boxers? A Double-Blind, Placebo-Controlled Study.
    Ozan M; Buzdagli Y; Eyipinar CD; Baygutalp NK; Yüce N; Oget F; Kan E; Baygutalp F · Nutrients · 2022
    Randomized trial20 participantsEnergy forCaffeine
  35. Trait Energy and Fatigue Modify the Effects of Caffeine on Mood, Cognitive and Fine-Motor Task Performance: A Post-Hoc Study.
    Fuller DT; Smith ML; Boolani A · Nutrients · 2021
    Randomized trialEnergy forCaffeine
  36. Synergistic effects of creatine, carbs, protein on repeated sprint performance.
    Wang Y; Wei H; Cheng X; Chen Z · Scientific reports · 2026
    Randomized trial60 participantsEnergy forCreatine
  37. The Effects of Creatine Monohydrate Supplementation on Recovery from Eccentric Exercise-Induced Muscle Damage: A Double-Blind, Randomized, Placebo-Controlled Trial Considering Sex and Age Differences.
    Yamaguchi S; Inami T; Nishioka T; Morito A; Ishiyama K; Murayama M · Nutrients · 2025
    Randomized trial40 participantsEnergy forCreatine
  38. The Effect of Prior Creatine Intake for 28 Days on Accelerated Recovery from Exercise-Induced Muscle Damage: A Double-Blind, Randomized, Placebo-Controlled Trial.
    Yamaguchi S; Inami T; Ishida H; Morito A; Yamada S; Nagata N; Murayama M · Nutrients · 2024
    Randomized trial20 participantsEnergy forCreatine
  39. Creatine supplementation attenuates the rate of fatigue development during intermittent isometric exercise performed above end-test torque.
    Abdalla LHP; Broxterman RM; Greco CC; Denadai BS · Experimental physiology · 2021
    Randomized trial16 participantsEnergy forCreatine
  40. The effect of continuous low dose creatine supplementation on force, power, and total work.
    Burke DG; Silver S; Holt LE; Smith Palmer T; Culligan CJ; Chilibeck PD · International journal of sport nutrition and exercise metabolism · 2000
    Randomized trial41 participantsEnergy forCreatine
  41. Effects of Caffeine Intake on Endurance Running Performance and Time to Exhaustion: A Systematic Review and Meta-Analysis.
    Wang Z; Qiu B; Gao J; Del Coso J · Nutrients · 2023
    Meta-analysis254 participants21 studies pooledFitness forCaffeine
  42. Acute Effects of Caffeine Supplementation on Movement Velocity in Resistance Exercise: A Systematic Review and Meta-analysis.
    Raya-González J; Rendo-Urteaga T; Domínguez R; Castillo D; Rodríguez-Fernández A; Grgic J · Sports medicine (Auckland, N.Z.) · 2021
    Meta-analysis12 studies pooledFitness forCaffeine
  43. Sex Differences in the Ergogenic Response of Acute Caffeine Intake on Muscular Strength, Power and Endurance Performance in Resistance-Trained Individuals: A Randomized Controlled Trial.
    Montalvo-Alonso JJ; Ferragut C; Del Val-Manzano M; Valadés D; Roberts J; Pérez-López A · Nutrients · 2024
    Randomized trial76 participantsFitness forCaffeine
  44. Can I Have My Coffee and Drink It? A Systematic Review and Meta-analysis to Determine Whether Habitual Caffeine Consumption Affects the Ergogenic Effect of Caffeine.
    Carvalho A; Marticorena FM; Grecco BH; Barreto G; Saunders B · Sports medicine (Auckland, N.Z.) · 2022
    Meta-analysis60 studies pooledFitness forCaffeine
  45. Creatine in combination with resistance training and improvement in muscle strength: evaluation of a health claim pursuant to Article 13(5) of Regulation (EC) No 1924/2006.
    EFSA Panel on Dietetic Products, Nutrition and Allergies (NDA) · EFSA journal. European Food Safety Authority · 2026
    Guideline / consensusFitness forCreatine
  46. Effect of creatine and weight training on muscle creatine and performance in vegetarians.
    Burke DG; Chilibeck PD; Parise G; Candow DG; Mahoney D; Tarnopolsky M · Medicine and science in sports and exercise · 2004
    Randomized trial42 participantsFitness forCreatine
  47. Long-term creatine intake is beneficial to muscle performance during resistance training.
    Vandenberghe K; Goris M; Van Hecke P; Van Leemputte M; Vangerven L; Hespel P · Journal of applied physiology (Bethesda, Md. : 1985) · 1998
    Randomized trial19 participantsFitness forCreatine
  48. Effects of Combined Versus Single Supplementation of Creatine, Beta-Alanine, and L-Citrulline During Short Sprint Interval Training on Basketball Players' Performance: A Double-Blind Randomized Placebo-Controlled Trial.
    Li M; Sheykhlouvand M · International journal of sports physiology and performance · 2025
    Randomized trial48 participantsFitness forCreatine
  49. The Additive Effects of Creatine Supplementation and Exercise Training in an Aging Population: A Systematic Review of Randomized Controlled Trials.
    Stares A; Bains M · Journal of geriatric physical therapy (2001) · 2021
    Systematic review17 studies pooledFitness forCreatine
  50. Additive effects of beta-alanine and sodium bicarbonate on upper-body intermittent performance.
    Tobias G; Benatti FB; de Salles Painelli V; Roschel H; Gualano B; Sale C; Harris RC; Lancha AH; Artioli GG · Amino acids · 2013
    Randomized trial37 participantsFitness forSodium
  51. Sodium Hyperhydration Improves Performance With No Change in Thermal and Cardiovascular Strain in Female Cyclists Exercising in the Heat Across the Menstrual Cycle.
    Convit L; Orellana L; Périard JD; Carr AJ; Warmington S; Beaugeois M; Abraham A; Snipe RMJ · International journal of sport nutrition and exercise metabolism · 2025
    Randomized trial12 participantsFitness forSodium
  52. Sodium bicarbonate supplementation improves severe-intensity intermittent exercise under moderate acute hypoxic conditions.
    Deb SK; Gough LA; Sparks SA; McNaughton LR · European journal of applied physiology · 2018
    Randomized trial11 participantsFitness forSodium
  53. International Society of Sports Nutrition position stand: sodium bicarbonate and exercise performance.
    Grgic J; Pedisic Z; Saunders B; Artioli GG; Schoenfeld BJ; McKenna MJ; Bishop DJ; Kreider RB; Stout JR; Kalman DS; Arent SM; VanDusseldorp TA; Lopez HL; Ziegenfuss TN; Burke LM; Antonio J; Campbell BI · Journal of the International Society of Sports Nutrition · 2021
    Guideline / consensusFitness forSodium
  54. The effects of sodium bicarbonate ingestion on swimming interval performance in trained competitive swimmers.
    Gough LA; Newbury JW; Price M · European journal of applied physiology · 2023
    Randomized trial14 participantsFitness forSodium
  55. Taurine supplementation enhances anaerobic power in elite speed skaters: A double-blind, randomized, placebo-controlled, crossover study.
    Buzdağlı Y; Eyipınar CD; Öget F; Şıktar E; Forbes SC; Tekin A · Biology of sport · 2023
    Randomized trial30 participantsFitness forTaurine
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    Balshaw TG; Bampouras TM; Barry TJ; Sparks SA · Amino acids · 2013
    Randomized trial8 participantsFitness forTaurine
  57. Effects of different doses of taurine supplementation on repeated-sprint performance after exhaustive exercise in a high temperature and humidity environment.
    Cheng X; Lin Y; Li Z · Frontiers in nutrition · 2026
    Randomized trial16 participantsFitness forTaurine
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    Waldron M; Patterson SD; Jeffries O · Amino acids · 2020
    Randomized trial12 participantsFitness forTaurine
  59. Acute taurine supplementation enhances thermoregulation and endurance cycling performance in the heat.
    Page LK; Jeffries O; Waldron M · European journal of sport science · 2019
    Randomized trial11 participantsFitness forTaurine
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    Randomized trial32 participantsMental Focus forCaffeine
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    Smith AP; Christopher G; Sutherland D · Journal of psychopharmacology (Oxford, England) · 2013
    Randomized trial70 participantsMental Focus forCaffeine
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    Wesensten NJ; Killgore WD; Balkin TJ · Journal of sleep research · 2006
    Randomized trial48 participantsMental Focus forCaffeine
  63. Effects of caffeine on mood and performance: a study of realistic consumption.
    Brice CF; Smith AP · Psychopharmacology · 2003
    Clinical trial24 participantsMental Focus forCaffeine
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    Randomized trial24 participantsMental Focus forCaffeine
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    Randomized trial60 participantsMetabolism Boost forCaffeine
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    Rumpler W; Seale J; Clevidence B; Judd J; Wiley E; Yamamoto S; Komatsu T; Sawaki T; Ishikura Y; Hosoda K · The Journal of nutrition · 2001
    Randomized trial12 participantsMetabolism Boost forCaffeine
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    Gutiérrez-Hellín J; Aguilar-Navarro M; Ruiz-Moreno C; Muñoz A; Varillas-Delgado D; Amaro-Gahete FJ; Del Coso J · European journal of nutrition · 2023
    Randomized trial18 participantsMetabolism Boost forCaffeine
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    Koot P; Deurenberg P · Annals of nutrition & metabolism · 1995
    Randomized trial12 participantsMetabolism Boost forCaffeine
  69. Caffeine Increases Work Done above Critical Power, but Not Anaerobic Work.
    Silveira R; Andrade-Souza VA; Arcoverde L; Tomazini F; Sansonio A; Bishop DJ; Bertuzzi R; Lima-Silva AE · Medicine and science in sports and exercise · 2018
    Randomized trial9 participantsMetabolism Boost forCaffeine
  70. Creatine target engagement with brain bioenergetics: a dose-ranging phosphorus-31 magnetic resonance spectroscopy study of adolescent females with SSRI-resistant depression.
    Kondo DG; Forrest LN; Shi X; Sung YH; Hellem TL; Huber RS; Renshaw PF · Amino acids · 2017
    Randomized trialMetabolism Boost forCreatine
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    Pinto CL; Botelho PB; Pimentel GD; Campos-Ferraz PL; Mota JF · Amino acids · 2017
    Systematic reviewMetabolism Boost forCreatine
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    Andrews R; Greenhaff P; Curtis S; Perry A; Cowley AJ · European heart journal · 1998
    Clinical trialMetabolism Boost forCreatine
  73. A comprehensive review of the physiology and evidence base to guide the use of ergogenic and medical supplements for enhanced cycling performance.
    Rowland A; Edwards S; Prieto-Bellver G; Menz B; Rowland A; Cornelisse E; Karapetis CS; Wallen MP; Hopkins AM · Journal of the International Society of Sports Nutrition · 2026
    Narrative reviewMetabolism Boost forCreatine
  74. Creatine Supplementation Beyond Athletics: Benefits of Different Types of Creatine for Women, Vegans, and Clinical Populations-A Narrative Review.
    Gutiérrez-Hellín J; Del Coso J; Franco-Andrés A; Gamonales JM; Espada MC; González-García J; López-Moreno M; Varillas-Delgado D · Nutrients · 2025
    Narrative reviewMetabolism Boost forCreatine
  75. Taurine supplementation as a therapeutic strategy for cellular senescence and chronic inflammation in long COVID: a systematic review and meta-analysis.
    Wang K; Ma CH; Khoramjoo M; Kung JY; Oudit GY · BMC infectious diseases · 2026
    Meta-analysis1,030 participants27 studies pooledMetabolism Boost forTaurine
  76. Effect of Long-Term Taurine Supplementation on the Lipid and Glycaemic Profile in Adults with Overweight or Obesity: A Systematic Review and Meta-Analysis.
    Sun Q; Wang J; Wang H; Yu H; Wan K; Ma F; Wang R · Nutrients · 2025
    Meta-analysis9 studies pooledMetabolism Boost forTaurine
  77. The effects of taurine supplementation on obesity, blood pressure and lipid profile: A meta-analysis of randomized controlled trials.
    Guan L; Miao P · European journal of pharmacology · 2021
    Meta-analysis12 studies pooledMetabolism Boost forTaurine
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    Zhang M; Bi LF; Fang JH; Su XL; Da GL; Kuwamori T; Kagamimori S · Amino acids · 2005
    Randomized trial30 participantsMetabolism Boost forTaurine
  79. Use of skeletal muscle fiber composition to assess relationship between amino acid metabolism and insulin sensitivity.
    Magnusson TE; Blackwood SJ; Tischer D; Strmeň T; Pontén M; Edman S; Horwath O; Apró W; Moberg M; Chorell E; Katz A · European journal of endocrinology · 2025
    Cross-sectional study36 participantsMetabolism Boost forTaurine
  80. The effect of 6 days of alpha glycerylphosphorylcholine on isometric strength
    David Bellar, Nina R LeBlanc, Brian Campbell · Journal of the International Society of Sports Nutrition · 2015
    Randomized trial13 participantsMuscle Gain forAlpha-GPC
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    Wu W; Chen Z; Zhou H; Wang L; Li X; Lv Y; Sun T; Yu L · Nutrients · 2024
    Meta-analysis14 studies pooledMuscle Gain forCaffeine
  82. Acute caffeine intake improves muscular strength, power, and endurance performance, reversing the time-of-day effect regardless of muscle activation level in resistance-trained males: a randomized controlled trial.
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    Randomized trial13 participantsMuscle Gain forCaffeine
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    Grgic J; Grgic I; Pickering C; Schoenfeld BJ; Bishop DJ; Pedisic Z · British journal of sports medicine · 2020
    Systematic review21 studies pooledMuscle Gain forCaffeine
  84. Effects of caffeine intake on muscle strength and power: a systematic review and meta-analysis.
    Grgic J; Trexler ET; Lazinica B; Pedisic Z · Journal of the International Society of Sports Nutrition · 2018
    Meta-analysis20 studies pooledMuscle Gain forCaffeine
  85. Caffeine increases strength and power performance in resistance-trained females during early follicular phase.
    Norum M; Risvang LC; Bjørnsen T; Dimitriou L; Rønning PO; Bjørgen M; Raastad T · Scandinavian journal of medicine & science in sports · 2021
    Randomized trial15 participantsMuscle Gain forCaffeine
  86. The Effect of Creatine Supplementation on Resistance Training-Based Changes to Body Composition: A Systematic Review and Meta-analysis.
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    Meta-analysis362 participants12 studies pooledMuscle Gain Weight Loss forCreatine
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    Wang Z; Qiu B; Li R; Han Y; Petersen C; Liu S; Zhang Y; Liu C; Candow DG; Del Coso J · Nutrients · 2024
    Meta-analysis509 participants23 studies pooledMuscle Gain forCreatine
  88. Comparative Effects of Dietary Protein, Creatine, and Omega-3 Supplementation on Muscle Strength, Endurance, and Recovery in Trained Athletes: A Systematic Review and Network Meta-Analysis.
    Wang Z; Qin G; Kim BM · Nutrients · 2026
    Meta-analysis1,211 participants35 studies pooledMuscle Gain forCreatine
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    Chilibeck PD; Kaviani M; Candow DG; Zello GA · Open access journal of sports medicine · 2020
    Meta-analysis721 participants22 studies pooledMuscle Gain forCreatine
  90. Creatine supplementation during resistance training in older adults-a meta-analysis.
    Devries MC; Phillips SM · Medicine and science in sports and exercise · 2014
    Meta-analysis357 participantsMuscle Gain forCreatine
  91. Treatment of dementia with neurotransmission modulation.
    Doggrell SA; Evans S · Expert opinion on investigational drugs · 2004
    Narrative reviewProductivity Boost forAlpha-GPC
  92. Effects of caffeine on alertness.
    Zwyghuizen-Doorenbos A; Roehrs TA; Lipschutz L; Timms V; Roth T · Psychopharmacology · 1990
    Randomized trial24 participantsProductivity Boost forCaffeine
  93. Effects of Different Sources of Low-Dose Caffeine on Mood/Arousal and Cognitive Performance.
    Irwin C; McCartney D; Grant G; Delang N; Bartrim K; Cox GR; Desbrow B · Perceptual and motor skills · 2023
    Randomized trial22 participantsProductivity Boost forCaffeine
  94. Effects of caffeine, sleep loss, and stress on cognitive performance and mood during U.S. Navy SEAL training. Sea-Air-Land.
    Lieberman HR; Tharion WJ; Shukitt-Hale B; Speckman KL; Tulley R · Psychopharmacology · 2003
    Randomized trial68 participantsProductivity Boost forCaffeine
  95. A review of caffeine's effects on cognitive, physical and occupational performance.
    McLellan TM; Caldwell JA; Lieberman HR · Neuroscience and biobehavioral reviews · 2017
    Narrative reviewProductivity Boost forCaffeine
  96. Acute caffeine supplementation as a nutrition-based strategy to mitigate sleep-loss-related cognitive and operational performance impairments in military personnel: a systematic review and meta-analysis.
    Wang R; Wang W; Meng L; Hao G; Gu G · Frontiers in nutrition · 2026
    Meta-analysis7 studies pooledProductivity Boost forCaffeine
  97. Changes in caffeine intake and long-term weight change in men and women.
    Lopez-Garcia E; van Dam RM; Rajpathak S; Willett WC; Manson JE; Hu FB · The American journal of clinical nutrition · 2006
    Cohort study58,157 participantsWeight Loss forCaffeine
  98. Does caffeine ingestion before a short-term sprint interval training promote body fat loss?
    Ferreira GA; Felippe LC; Bertuzzi R; Bishop DJ; Ramos IS; De-Oliveira FR; Lima-Silva AE · Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas · 2020
    Randomized trial20 participantsWeight Loss forCaffeine
  99. Eight Weeks of Sprint Interval Training With Adding Caffeine Ingestion Leads to Greater Improvements in Health-Related Physiological Parameters in Obese Male Adults.
    Zhiang J; Song Q · Physiological research · 2026
    Randomized trial30 participantsWeight Loss forCaffeine
  100. Caffeine treatment prevented from weight regain after calorie shifting diet induced weight loss.
    Davoodi SH; Hajimiresmaiel SJ; Ajami M; Mohseni-Bandpei A; Ayatollahi SA; Dowlatshahi K; Javedan G; Pazoki-Toroudi H · Iranian journal of pharmaceutical research : IJPR · 2014
    Non-randomized trial60 participantsWeight Loss forCaffeine
  101. The effects of caffeine intake on weight loss: a systematic review and dos-response meta-analysis of randomized controlled trials.
    Tabrizi R; Saneei P; Lankarani KB; Akbari M; Kolahdooz F; Esmaillzadeh A; Nadi-Ravandi S; Mazoochi M; Asemi Z · Critical reviews in food science and nutrition · 2020
    Meta-analysis606 participants13 studies pooledWeight Loss forCaffeine
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    Forbes SC; Candow DG; Krentz JR; Roberts MD; Young KC · Journal of functional morphology and kinesiology · 2021
    Meta-analysis609 participants19 studies pooledWeight Loss forCreatine
  103. Effects of creatine supplementation with and without exercise and diet intervention on body composition, cognitive function, and markers of health in middle-aged and older adults.
    Chun J; Liu Y; Kibler GL; Lee H; Babakhani K; Rhoades N; Bivins I; Ko J; Dickerson B; Gonzalez DE; Sowinski RJ; Rasmussen CJ; Kreider RB · Journal of the International Society of Sports Nutrition · 2026
    Randomized trial64 participantsWeight Loss forCreatine
  104. Creatine supplementation protocols with or without training interventions on body composition: a GRADE-assessed systematic review and dose-response meta-analysis.
    Pashayee-Khamene F; Heidari Z; Asbaghi O; Ashtary-Larky D; Goudarzi K; Forbes SC; Candow DG; Bagheri R; Ghanavati M; Dutheil F · Journal of the International Society of Sports Nutrition · 2024
    Meta-analysis3,655 participants143 studies pooledWeight Loss forCreatine
  105. Effects of Creatine Monohydrate Gummies on Performance and Body Composition in Female Beach Volleyball Athletes.
    Pereira F; Forbes SC; Romano V; Christopher P; Santana JC; Antonio J · Journal of functional morphology and kinesiology · 2026
    Randomized trial32 participantsWeight Loss forCreatine