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Glutathione 500 mg

NOW
4.6
★ ★ ★ ★ ★
(102289 ratings)
Glutathione 500 mg
Milk Thistle 100 mg
Product Image
Score80
A strong, transparent glutathione and milk thistle capsule with a useful add-on and ordinary delivery.
How scoring works
Quantity:60 Capsule(s) • (60 servings)
Goals:
Anti-Inflammatory Support

Score 80

A strong, transparent glutathione and milk thistle capsule with a useful add-on and ordinary delivery.
How scoring works

Also available as

2 options
120 servings Milk Thistle 100 mg, Glutathione 500 mg • 120 Capsule(s) • 120 servings $37.30 ($0.31 per serving) 30 servings Milk Thistle 100 mg, Glutathione 500 mg • 30 Capsule(s) • 30 servings $13.90 ($0.46 per serving)
$23.21($0.38 per serving)
Amazon
$ 23.21
Daily Vita
$ 25.50
Vitacost
$ 28.47
Pure Formulas
$ 25.37
iHerb
$ 26.93
Walmart
$ 23.99
iHerb
$ 26.93
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Analysis

The capsule provides 500 mg glutathione with 100 mg standardized milk thistle extract. Fifty milligrams of alpha-lipoic acid adds another antioxidant pathway.

The active amounts are clear and the formula avoids a proprietary blend. Glutathione delivery is not described as liposomal or otherwise enhanced, so absorption is less predictable than with specialized formats.

The simple combination fits users seeking antioxidant and milk thistle support in one capsule. People using glucose-lowering medicines should monitor compatibility with alpha-lipoic acid.

Who is it for
  • Adults seeking oral glutathione
  • People wanting glutathione with milk thistle
Best for
  • Antioxidant support
  • Simple liver-focused routines

Pros

  • Provides 500 mg glutathione
  • Includes standardized milk thistle
  • No proprietary blend

Cons

  • No enhanced glutathione delivery
  • Alpha-lipoic acid amount is modest
  • Not targeted specifically to inflammation

Warnings

  • Alpha-lipoic acid may add to insulin or diabetes medicines and increase low-blood-sugar risk.

Nutrient quality

80 Highest impact

Glutathione is not identified as reduced or enhanced-delivery, and milk thistle lacks a standardization percentage. The glutathione amount is meaningful, while milk thistle and alpha-lipoic acid are supportive but modest.

Ingredient transparency

79 High impact

All three active ingredients have clear amounts. Excipients and daily directions are absent from the supplied data, which leaves some label details uncertain.

Customer satisfaction

71 High impact

The aggregate satisfaction average is favorable, though no detailed feedback is supplied. The very large volume makes the aggregate satisfaction signal stable.

Value for money

89 Highest impact

A meaningful core dose and focused supporting ingredients justify the formula well. The serving provides favorable cost efficiency for the glutathione amount.

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Goals

Anti-Inflammatory Support
Anti-Inflammatory Support
Impact
Highest effect
B+ Goal FitB- Strength of SupportB CoverageA Formula Quality
Glutathione · 500 mg

Glutathione directly supports antioxidant control, while milk thistle and alpha lipoic acid add complementary redox support. Human and mechanistic evidence supports glutathione-related oxidative balance, although oral benefit depends on formulation and absorption.

The 500 mg glutathione amount is meaningful, while milk thistle at 100 mg and alpha lipoic acid at 50 mg are supportive but modest. All amounts are disclosed, but the glutathione form and milk-thistle standardization are not specified.

Study evidence
Glutathione Disputed 2 studies

Ingredients

IngredientAmount per serving
Glutathione
500 mg
Milk Thistle extract (Silymarin Flavonoids)
 100 mg
Alpha Lipoic Acid
50 mg
Gluten Free Adults 18–50 Vegan Kosher Dairy Free Vegetarian
Report overview
Glutathione · 500 mg OverallScore54
F Active Ingredient Quality & BioavailabilityA+ Dose, Safety & Label TransparencyB- Value

The single capsule delivers a substantial, clearly disclosed glutathione amount with supportive milk thistle and alpha-lipoic acid. The glutathione state and delivery method are not specified, so absorption quality remains uncertain. Cost efficiency is still favorable for the amount provided.

View ingredientView products
Milk Thistle (Silymarin Flavonoids) · 100 mg OverallScore19
F Active Ingredient Quality & BioavailabilityF Dose, Safety & Label TransparencyD- Value

The formula identifies silymarin flavonoids but does not state their percentage or resulting active amount. One dry capsule is convenient, although it offers no special absorption support and does not name the plant part. The low serving cost helps, but potency remains uncertain.

View ingredientView products
Loading alternative details
78 Performance

Glutathione 500 mg

NOW
<p>Compared with the original, it retains Milk Thistle, and Glutathione and remains aligned with anti-inflammatory support. A substantial glutathione amount with milk thistle and alpha-lipoic acid creates a focused antioxidant formula. The glutathione state and milk-thistle standardization are not specified, and this package offers only moderate value compared with larger versions.</p>
84 Performance

L-Glutathione Reduced 500 mg

Healthy Origins
<p>Compared with the original, it retains Glutathione and remains aligned with anti-inflammatory support. A substantial branded reduced-glutathione amount provides strong dose and source quality. Comparatively mixed customer sentiment contrasts with economical servings and excellent formula value.</p>
83 Performance

Glutathione Reduced 500 mg

Jarrow Formulas
<p>Compared with the original, it retains Glutathione and remains aligned with anti-inflammatory support. A substantial reduced-glutathione amount provides strong antioxidant depth. Extensive customer evidence is mixed, while favorable serving economics support good value.</p>
85 Budget

Glutathione 500 mg

NOW
<p>It lowers recurring cost while retaining Milk Thistle, and Glutathione from the original's ingredient focus. Reduced glutathione is clearly identified at a substantial amount, with milk thistle and alpha-lipoic acid providing focused antioxidant support at strong value. Standard capsule delivery leaves some absorption uncertainty, and alpha-lipoic acid may add to glucose-lowering effects from insulin or diabetes medicines.</p>
77 Budget

Milk Thistle 30:1 Extract

Jarrow Formulas
<p>It lowers recurring cost while retaining Milk Thistle from the original's ingredient focus. A concentrated milk thistle extract uses relevant seed and fruit sourcing and offers especially accessible serving value. The focused design is appealing, though repeated label entries and incomplete active-flavonoid detail keep potency somewhat uncertain.</p>
84 Budget

Milk Thistle

Kroeger Herb Products Co.
<p>It lowers recurring cost while retaining Milk Thistle from the original's ingredient focus. A separate silymarin amount from milk thistle seed makes potency unusually easy to assess. Favorable serving value and a sizeable aggregate customer base strengthen the case.</p>
85 Value

Milk Thistle

Paradise
<p>It combines a lower recurring cost with Milk Thistle, supporting a practical value case against the original. A substantial stated silymarin amount provides focused milk thistle potency in a simple formula. Strong aggregate customer metrics and favorable serving value make it competitive among conventional options.</p>
82 Value

Glutathione 250 mg

NOW
<p>It combines a lower recurring cost with Glutathione, supporting a practical value case against the original. A meaningful glutathione amount provides focused antioxidant support at favorable serving value. Extensive customer evidence supports good practical value despite that limitation.</p>
82 Value

L-Glutathione 100 mg

Swanson
<p>It combines a lower recurring cost with Glutathione, supporting a practical value case against the original. Branded Setria glutathione supports ingredient confidence at a modest amount. Extensive customer evidence and exceptionally economical servings support good value.</p>
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Sources

Published studies used for the product analysis and the top-ranked studies for each ingredient and goal.

  1. Serum type III procollagen, procollagen V, tumour necrosis factor-a, interleukin-6 in liver cirrhosis after antiviral treatment.
    Li W; Liu X; Bi F · Journal of medical biochemistry · 2025
    Randomized trial92 participantsAnti-Inflammatory Support forGlutathione
  2. Evaluation of the antioxidant and anti-inflammatory effect of sublingual glutathione on COPD patients.
    Farag A; Abass W; Qassem H · Journal of medicine and life · 2024
    Cohort study50 participantsAnti-Inflammatory Support forGlutathione