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Milk Thistle Liver Detox

Irwin Naturals
4.7
★ ★ ★ ★ ★
(1175 ratings)
Milk Thistle 150 mg
Turmeric 100 mg
Protein 1 Gram(s)
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Score70
A coherent liver-support blend offers useful ingredient breadth. Missing silymarin and curcuminoid standardization keeps dose quality uncertain.
How scoring works
Quantity:60 Liquid(s) • (30 servings)
Goals:
Detoxification

Score 70

A coherent liver-support blend offers useful ingredient breadth. Missing silymarin and curcuminoid standardization keeps dose quality uncertain.
How scoring works
$18.99($0.63 per serving)
iHerb
$ 22.99
Pure Formulas
$ 22.99
Vitacost
$ 24.87
Amazon
$ 18.99
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Analysis

Milk thistle seed extract at 150 mg is the lead botanical, supported by artichoke, dandelion, turmeric, and schisandra. The combination covers a recognizable liver, bile, and antioxidant theme without relying on a single proprietary blend.

Milk thistle lacks a stated silymarin yield, and turmeric has no curcuminoid standardization. Boldo, schisandra, beet, licorice, and BioPerine are present at modest or small amounts, so their independent contribution is uncertain.

Flaxseed oil provides an oil-based delivery matrix and all active quantities are disclosed. The many botanicals increase interaction complexity, while the unstandardized lead ingredients limit confidence in potency.

Who is it for
  • Adults seeking a broad liver-support botanical blend
  • People who want milk thistle with artichoke and dandelion
  • Users comfortable with a multi-herb formula
Best for
  • General liver-support routines
  • Botanical antioxidant support
  • Users who value ingredient breadth over standardized potency

Pros

  • Combines several liver-focused botanicals
  • Includes 100 mg vitamin C
  • Uses an oil-based softgel matrix
  • Discloses each active amount

Cons

  • Milk thistle silymarin yield is not stated
  • Turmeric is not standardized
  • Several supporting herbs are lightly dosed
  • Complex formula raises interaction burden

Warnings

  • Licorice may raise blood pressure or lower potassium in susceptible users
  • Turmeric may add to bleeding risk with anticoagulant or antiplatelet medicines
  • Milk thistle and dandelion may trigger reactions in people sensitive to ragweed-family plants
  • BioPerine and the multi-herb blend can alter medication exposure and warrant interaction review

Nutrient quality

68 High impact

The formula covers several relevant liver and digestive pathways. Generic extract forms, unknown active yields, and modest supporting doses limit nutrient quality.

Ingredient transparency

76 High impact

Every active has a stated amount and no proprietary blend obscures the formula. Missing standardization, directions, and excipients prevent confident dose interpretation.

Customer satisfaction

71 High impact

The supplied average is exceptionally strong and supported by a very large review base. No qualitative experience details verify repeated benefits or complaints.

Value for money

63 Moderate impact

The moderate serving cost buys a broad, coherent botanical blend. Unknown main active yields and several token additions keep value from being stronger.

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Goals

Detoxification
Detoxification
Impact
Moderate effect
B- Goal FitD- Strength of SupportC CoverageC- Formula Quality
Milk Thistle · 150 mgVitamin C · 100 mg

Milk thistle, artichoke, dandelion, turmeric, and schisandra create a recognizable liver-and-bile support theme. The formula reaches several relevant antioxidant and digestive pathways.

Milk thistle lacks silymarin standardization, and most supporting herbs are present at modest or token amounts. Licorice can raise blood pressure or lower potassium in susceptible users, although its amount here is small.

Study evidence
Milk Thistle Supportive 46 studies

Ingredients

IngredientAmount per serving
Calories
15 Calorie(s)
Total Fat
1 Gram(s)
Total Carbohydrates
1 Gram(s)
Protein
1 Gram(s)
Vitamin C (Ascorbic Acid)
 100 mg
Flaxseed Oil
1000 mg
Milk Thistle Seed Extract
150 mg
Artichoke Leaf Extract
100 mg
Dandelion Root Extract (Taraxacum mongolicum Root Extract)
 100 mg
Turmeric Root Extract
100 mg
Boldo leaf extract
60 mg
Schisandra Fruit Extract (Schisandra chinensis fruit extract)
 60 mg
Beet, Powder
40 mg
Licorice, Powder
20 mg
BioPerine Complex
3 mg
Adults 18–50 Women
Report overview
Milk Thistle · 150 mg OverallScore28
C Active Ingredient Quality & BioavailabilityF Dose, Safety & Label TransparencyF Value

A 150 mg seed extract is supplied in an oil-based softgel that may improve solubility. The active silymarin yield is not disclosed, so dose adequacy remains uncertain. The serving cost is high for an extract with unknown potency.

View ingredientView products
Turmeric · 100 mg OverallScore20
F Active Ingredient Quality & BioavailabilityF Dose, Safety & Label TransparencyD- Value

Turmeric root extract is included, but its curcuminoid strength and active yield are not disclosed. The flaxseed-oil softgel may modestly support absorption, though the black pepper complex is below the amount needed for the strongest enhancement. Value is limited because the serving costs more than the median without a verified active dose.

View ingredientView products
Loading alternative details
81 Performance

Milk Thistle Phytosome 150 mg

Natural Factors HerbalFactors
<p>A silymarin phytosome gives the main ingredient a defined delivery form while retaining dandelion, turmeric, and artichoke. The serving cost is lower and the formula avoids licorice, although the supplied details do not state the exact silymarin yield.</p>
78 Performance

Silymarin Milk Thistle Extract 150 mg

NOW
<p>A declared silymarin-flavonoid form and a larger turmeric amount make the two principal botanicals easier to assess than in the original. The simpler formula is lower in serving cost but does not include artichoke, dandelion, schisandra, or black pepper.</p>
74 Performance

Active Liver

New Nordic
<p>Clearly stated silymarin, artichoke, and turmeric amounts create a focused liver-support formula with stronger core doses than the original. It costs slightly more per serving and leaves out dandelion, schisandra, black pepper, and the original vitamin and oil components.</p>
80 Budget

Silymarin Complex

California Gold Nutrition
<p>The much lower serving cost provides a standardized silymarin amount that is twice the original milk-thistle quantity, while retaining dandelion, artichoke, turmeric, ginger, and black pepper. It omits schisandra, boldo, beet, flaxseed oil, and vitamin C, but the main milk-thistle active is more clearly defined.</p>
74 Budget

Liv-Gall Cleanse

Natural Factors HerbalFactors
<p>A much lower serving cost keeps milk thistle, artichoke, turmeric, and dandelion in a compact formula with all amounts disclosed. The milk-thistle amount is lower and no active yields are stated, yet it avoids the original licorice and crowded supporting blend.</p>
76 Budget

Silymarin Milk Thistle Extract 150 mg

NOW
<p>The lower-cost serving doubles the stated milk-thistle amount and supplies substantially more turmeric in a simple two-ingredient formula. The form does not specify a silymarin yield, and the product drops artichoke, dandelion, schisandra, and the original absorption support.</p>
79 Value

Silymarin Complex

California Gold Nutrition
<p>A much lower serving cost pairs a defined silymarin amount with dandelion, artichoke, turmeric, ginger, and piperine. It closely covers the original core botanicals while omitting licorice, though it does not include schisandra, boldo, flaxseed oil, or vitamin C.</p>
69 Value

Liver Detox & Blood Refresh

Irwin Naturals
<p>A defined silymarin amount with dandelion, turmeric, burdock, and well-chosen mineral forms provides broader disclosed support at a similar serving cost. The larger formula introduces many extra botanicals and nutrients, while artichoke and schisandra from the original are absent.</p>
65 Value

Super Thisilyn

Nature's Way
<p>A defined silymarin amount is joined by artichoke, dandelion, curcuminoids, N-acetyl cysteine, methionine, and alpha-lipoic acid at a lower serving cost. Several supporting doses are modest, but the formula avoids the original licorice and states more active forms.</p>
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Sources

Published studies used for the product analysis and the top-ranked studies for each ingredient and goal.

  1. Are alterations needed in Silybum marianum (Silymarin) administration practices? A novel outlook and meta-analysis on randomized trials targeting liver injury.
    Shahsavari K; Ardekani SS; Ardekani MRS; Esfahani MM; Kazemizadeh H; Jamialahmadi T; Iranshahi M; Khanavi M; Hasanpour M · BMC complementary medicine and therapies · 2025
    Meta-analysis3,545 participants55 studies pooledDetoxification forMilk Thistle
  2. Impact of Silymarin Supplements on Liver Enzyme Levels: A Systematic Review.
    Calderon Martinez E; Herrera D; Mogan S; Hameed Z; Jangda AA; Khan TJ; Mroke P; Sajid S; Shah YR; Baig I · Cureus · 2023
    Systematic review3,846 participants29 studies pooledDetoxification forMilk Thistle
  3. The effect of silymarin on liver enzymes in patients taking isotretinoin: A randomized clinical trial.
    Mirnezami M; Jafarimanesh H; Rezagholizamenjany M; Alimoradian A; Ranjbaran M · Dermatologic therapy · 2021
    Randomized trial74 participantsDetoxification forMilk Thistle
  4. A double-blinded randomized controlled trial of silymarin for the prevention of antituberculosis drug-induced liver injury.
    Luangchosiri C; Thakkinstian A; Chitphuk S; Stitchantrakul W; Petraksa S; Sobhonslidsuk A · BMC complementary and alternative medicine · 2016
    Randomized trial55 participantsDetoxification forMilk Thistle
  5. Effect of 8 Weeks milk thistle powder (silymarin extract) supplementation on fatty liver disease in patients candidates for bariatric surgery.
    Mirhashemi SH; Hakakzadeh A; Yeganeh FE; Oshidari B; Rezaee SP · Metabolism open · 2022
    Observational studyDetoxification forMilk Thistle
  6. A randomized controlled trial to assess the safety and efficacy of silymarin on symptoms, signs and biomarkers of acute hepatitis.
    El-Kamary SS; Shardell MD; Abdel-Hamid M; Ismail S; El-Ateek M; Metwally M; Mikhail N; Hashem M; Mousa A; Aboul-Fotouh A; El-Kassas M; Esmat G; Strickland GT · Phytomedicine : international journal of phytotherapy and phytopharmacology · 2009
    Randomized trial105 participantsDetoxification forMilk Thistle
  7. Evaluation of Hepatoprotective Effect of Silymarin Among Under Treatment Tuberculosis Patients: A Randomized Clinical Trial.
    Marjani M; Baghaei P; Kazempour Dizaji M; Gorji Bayani P; Fahimi F; Tabarsi P; Velayati AA · Iranian journal of pharmaceutical research : IJPR · 2016
    Randomized trial70 participantsDetoxification forMilk Thistle
  8. The hepatorenal protective effects of silymarin in cancer patients receiving chemotherapy: a randomized, placebo-controlled trial.
    Erfanian SS; Ansari H; Javanmard SH; Amini Z; Hajigholami A · BMC complementary medicine and therapies · 2024
    Randomized trial100 participantsDetoxification forMilk Thistle
  9. A randomized double-blind, placebo-controlled study of therapeutic effects of silymarin in β-thalassemia major patients receiving desferrioxamine.
    Moayedi B; Gharagozloo M; Esmaeil N; Maracy MR; Hoorfar H; Jalaeikar M · European journal of haematology · 2013
    Randomized trial97 participantsDetoxification forMilk Thistle
  10. Effect of aerobic training with silymarin consumption on glycemic indices and liver enzymes in men with type 2 diabetes.
    Ghalandari K; Shabani M; Khajehlandi A; Mohammadi A · Archives of physiology and biochemistry · 2023
    Randomized trial60 participantsDetoxification forMilk Thistle
  11. Impact of silymarin-supplemented cookies on liver enzyme and inflammatory markers in non-alcoholic fatty liver disease patients.
    Jaffar HM; Bader Ul Ain H; Tufail T; Hanif A; Malik T · Food science & nutrition · 2024
    Clinical trial64 participantsDetoxification forMilk Thistle