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L-Tryptophan 500 mg

Bluebonnet
4.7
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(343 ratings)
Tryptophan 500 mg
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Score78
500 mg of L-tryptophan offers a focused serotonin-precursor approach with moderate value, though the formula covers only one pathway.
How scoring works
Quantity:60 Capsule(s) • (60 servings)
Goals:
Mood Support
Sleep Support
Stress Relief

Score 78

500 mg of L-tryptophan offers a focused serotonin-precursor approach with moderate value, though the formula covers only one pathway.
How scoring works
$24.76($0.41 per serving)
Daily Vita
$ 24.76
iHerb
$ 24.76
Amazon
$ 24.76
Vitacost
$ 24.76
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Analysis

L-tryptophan supplies a precursor used in serotonin and melatonin production. The 500 mg amount is a practical starting serving in a capsule.

The generic source does not disclose purity grade or fermentation details. Effects can vary with timing, diet, and individual metabolism.

No competing amino acids are listed, which supports focused timing away from protein-heavy meals. The formula is focused on one neurotransmitter pathway and does not provide broad sleep, stress, or mood coverage.

Who is it for
  • Adults seeking targeted sleep or mood support
  • Users starting with a moderate tryptophan amount
Best for
  • Evening or mood-support routines
  • Standalone tryptophan supplementation

Pros

  • Provides 500 mg of L-tryptophan
  • Contains no competing amino acids
  • Capsule format
  • Moderate value

Cons

  • Purity and fermentation details are not disclosed
  • Covers only one neurotransmitter pathway
  • Response may depend on meal timing and individual metabolism

Warnings

  • Do not combine L-tryptophan with SSRIs, SNRIs, MAO inhibitors, tramadol, triptans, or other serotonin-raising medicines without prescriber guidance.
  • Seek urgent care for agitation, confusion, heavy sweating, tremor, or a rapid heartbeat after a serotonergic combination because these can signal excessive serotonin.
  • L-tryptophan may cause drowsiness, so avoid driving or other alertness-dependent tasks until its effects are clear.

Nutrient quality

93 Highest impact

The standalone L-form avoids competing amino acids, but source-grade details are not supplied. The tryptophan amount is substantial for targeted supplementation.

Ingredient transparency

83 Highest impact

Every listed active has an individual amount and no proprietary blend hides key doses. Daily directions and the complete inactive-ingredient list are not supplied.

Customer satisfaction

65 High impact

The supplied average is favorable and the aggregate pool is limited. No specific feedback is provided to assess recurring complaints or whether experience matches the intended use.

Value for money

65 Moderate impact

Serving cost is high for the disclosed active amount. The focused design avoids paying for unnecessary active ingredients.

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Goals

Mood Support
Impact
Highest effect
B Goal FitA Strength of SupportC+ CoverageA+ Formula Quality

L-tryptophan supplies a serotonin and melatonin precursor with plausible relevance to mood and sleep. The 500 mg amount is a meaningful introductory serving, though human evidence for mood improvement is less consistent than its mechanism suggests.

The active form and amount are clearly disclosed in a single-ingredient product. Combining tryptophan with SSRIs, SNRIs, MAO inhibitors, tramadol, or other serotonergic drugs can increase serotonin-toxicity risk.

Study evidence
Tryptophan Mixed 1 study
Sleep Support
Impact
Highest effect
B+ Goal FitB+ Strength of SupportC CoverageA+ Formula Quality

The focused capsule supports the serotonin-to-melatonin pathway without extra actives. It provides 500 mg of clearly disclosed L-tryptophan for a defined sleep-related pathway.

The amount is at the lower end of common supplemental use and evidence for sleep improvement is mixed. L-tryptophan can add to serotonin activity when combined with SSRIs, MAO inhibitors, or other serotonergic medicines.

Study evidence
Tryptophan Mixed 1 study
Stress Relief
Impact
Highest effect
B- Goal FitA Strength of SupportC- CoverageA+ Formula Quality
Tryptophan · 500 mg

A 500 mg L-tryptophan serving may support serotonin production, mood balance, and relaxation under stress. Evidence is relevant for sleep and mood support, though effects depend on individual diet and serotonin biology.

The standalone format avoids competition from other large neutral amino acids and clearly states the dose. Tryptophan can add to the effects of SSRIs, MAO inhibitors, tramadol, or other serotonin-raising agents and may increase the risk of excessive serotonin.

Study evidence

Ingredients

IngredientAmount per serving
L-Tryptophan
500 mg
Gluten Free Adults 18–50 Vegan Kosher Dairy Free Sugar Free Women No Allergies Vegetarian
Report overview
Tryptophan · 500 mg OverallScore80
B- Active Ingredient Quality & BioavailabilityA+ Dose, Safety & Label TransparencyC Value

The standalone 500 mg dose is well aligned with common tryptophan use for sleep and mood support. The capsule lists the active amount clearly, but the source lacks added purity or fermentation details. Its cost per effective dose is moderate rather than especially economical.

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Sources

Published studies used for the product analysis and the top-ranked studies for each ingredient and goal.

  1. A systematic review of the effect of L-tryptophan supplementation on mood and emotional functioning
    Kikuchi AM, Tanabe A, Iwahori Y · Journal of Dietary Supplements · 2021
    Systematic review11 studies pooledMood Support forTryptophan
  2. The impact of tryptophan supplementation on sleep quality: a systematic review, meta-analysis, and meta-regression
    Clarinda N Sutanto, Wen Wei Loh, Jung Eun Kim · Nutrition Reviews · 2022
    Meta-analysis4 studies pooledSleep Support forTryptophan