Stress Relief

Mental & Cognitive Health

Reducing stress levels and promoting relaxation; key for mental health and well-being.

Best effective

Ashwagandha
Botanical
Studies have shown ashwagandha can reduce cortisol levels, a hormone associated with stress, and improve overall well-being in people under stress.
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Rhodiola
Botanical
As an adaptogen, Rhodiola has demonstrated effectiveness in helping the body adapt to stress and reduce its negative effects.
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Very effective

Eleuthero
Botanical
Eleuthero is known for its ability to support the adrenal glands, which play a crucial role in managing stress hormones. It helps regulate cortisol levels, thereby reducing the negative effects of chronic stress. Users often notice a greater sense of calm and resilience to stressors.
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GABA
Other
When the body is under stress, the nervous system can become overstimulated. GABA can counteract this by inhibiting the firing of neurons, thus lessening the physiological response to stress.
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Magnesium
Mineral
Magnesium is involved in the hypothalamic-pituitary-adrenal (HPA) axis, which regulates the body's stress response. Insufficient magnesium can exacerbate stress symptoms, and supplementation may contribute to stress reduction.
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St. John's Wort
Botanical
While not a primary anti-anxiety herb, the mood-regulating properties of St. John's Wort may also reduce stress levels. When mood is elevated and stabilized, individuals are more resilient to daily stressors and perceive them less intensely.
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Theanine
Amino Acid
Studies suggest L-theanine can increase alpha brain waves, which are associated with a state of relaxed alertness, and it may also modulate neurotransmitters involved in the stress response.
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Valerian
Botanical
Valerian's ability to interact with GABA receptors suggests that it can help reduce feelings of stress and anxiety by promoting a sense of calmness and relaxation, it might also assist in easing symptoms linked to anxiety, such as restlessness and nervousness.
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Decently effective

5-HTP
Amino Acid
Serotonin plays a crucial role in regulating mood and emotional responses, with higher levels associated with a sense of well-being and calmness. 5-HTP supplementation can support these effects, but results may vary between individuals and are not equivalent to medical treatment.
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Apigenin
Other
Research indicates that apigenin can modulate the hypothalamic-pituitary-adrenal (HPA) axis, a key component of the stress response system. This modulation can lead to a reduction in anxiety and stress levels.
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Bacopa
Botanical
Bacopa may influence stress hormones and calm the nervous system, though it's not as powerful as dedicated anti-stress agents. Regular use may have mild to moderate impact for stress reduction.
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Glycine
Amino Acid
Glycine acts as an inhibitory neurotransmitter, which can help to calm the nervous system and reduce feelings of stress and anxiety. It also helps regulate levels of cortisol in the body, which is often released in response to stress.
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Tryptophan
Amino Acid
Serotonin plays a role in reducing the body's stress response. While not a direct stress reducer, it promotes a sense of calm that can help in stressful situations. Tryptophan supplementation may support this process.
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Vitamin B5
Vitamin
Pantothenic acid is required for the synthesis of coenzyme A (CoA), which is crucial for the functioning of the adrenal glands. The adrenal glands produce hormones that help the body manage stress, including cortisol. B5 deficiency can contribute to adrenal fatigue, impacting the stress response.
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Partially effective

Melatonin
Other
Improved sleep quality due to melatonin supplementation can indirectly lower stress levels, although it's not a direct stress reliever.
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