L-Tryptophan 500 mg
Life Extension
L-Tryptophan 500 mg
4.7
★ ★ ★ ★ ★
(1594 ratings)
Tryptophan 500 mg
Score 75.0
A reliable, standard 500mg L-Tryptophan capsule from a reputable brand, offering good efficacy but not the best value compared to top alternatives.
Quantity: 90 Capsule(s)Servings size: 1 Vegetarian Capsule(s) (90 servings)
Selected goals:
Other goals:
Mood Support
Stress Relief
Sleep Support
leaderboard Score 75.0
A reliable, standard 500mg L-Tryptophan capsule from a reputable brand, offering good efficacy but not the best value compared to top alternatives.
insights Analysis
This Life Extension L-Tryptophan product is a straightforward 500mg capsule, offering a standard and widely accepted dosage for mood and sleep support. It benefits from Life Extension's strong brand reputation and a substantial number of positive online reviews, indicating reliability and user satisfaction. While it lacks additional cofactors like B vitamins found in some competitors, its simplicity makes it an appealing choice for those who prefer pure L-Tryptophan supplementation or manage their cofactors separately.
- Reputable brand known for quality.
- Standard and effective 500mg dose.
- High number of positive user reviews.
- Convenient capsule form.
- Lacks additional cofactors (like B vitamins) present in some alternative formulations that can enhance L-Tryptophan conversion.
- Not the most cost-effective option per milligram when compared to market leaders.
- Individuals sensitive to L-Tryptophan should start with a lower dose, although 500mg is generally well-tolerated.
$24.75($0.27 per serving)
 Vitacost | $ 24.75 | |
 iHerb | $ 24.75 | |
 Amazon | $ 24.75 |
bolt Effectiveness for goals
Tryptophan is an essential amino acid that serves as the sole precursor for the synthesis of serotonin in the body. After absorption, Tryptophan is converted to 5-hydroxytryptophan (5-HTP), which then converts to serotonin. This process is crucial for various physiological functions.
Tryptophan is an essential amino acid often supplemented to support the body's natural production of serotonin and melatonin. These compounds play roles in mood regulation, sleep cycles, and overall well-being. Its use is typically aimed at supporting these physiological processes.
L-Tryptophan is an essential amino acid, meaning the body cannot produce it and it must be obtained through diet. It serves as a precursor to serotonin, a neurotransmitter involved in mood regulation, and melatonin, a hormone that regulates sleep-wake cycles. Additionally, Tryptophan is involved in the synthesis of niacin (vitamin B3).
Some research suggests that Tryptophan may support sleep by increasing the production of serotonin, which is a precursor to melatonin. Melatonin is a hormone crucial for regulating the sleep-wake cycle. While findings are mixed, some individuals report benefits in sleep latency and quality.
L-Tryptophan is converted into 5-hydroxytryptophan (5-HTP), which then becomes serotonin, and subsequently melatonin in the pineal gland. Melatonin is a key hormone that helps regulate the body's circadian rhythm and promote sleep. By providing the building blocks for melatonin, Tryptophan may contribute to sleep onset and quality.
schedule Dosage, timing & forms
L-Tryptophan dosages are generally higher (e.g., 500-2000mg) compared to 5-HTP (e.g., 50-300mg), as 5-HTP is a more direct precursor to serotonin. Both are often taken before bed for sleep or split through the day for mood support. Their absorption and potential effects can differ due to their metabolic pathways.
Typical dosages for L-Tryptophan can range from 500 mg to 2000 mg per day, often split into multiple doses. The appropriate amount can depend on individual needs and the desired effect. It's generally advisable to start with a lower dose and adjust as needed, preferably under guidance.
Typical dosages for L-Tryptophan can vary based on individual needs and the intended use. For sleep support, dosages often range from 500 mg to 2000 mg taken before bedtime. For mood support, lower doses may be taken throughout the day. It's advisable to start with a lower dose and adjust as needed, preferably under guidance.
To optimize absorption and reduce competition with other amino acids, L-Tryptophan is often recommended to be taken on an empty stomach. Alternatively, taking it with a carbohydrate-rich, protein-low snack can enhance its transport into the brain. Taking it with protein-rich meals can hinder its effectiveness.
For sleep support, L-Tryptophan is often recommended to be taken 30-60 minutes before bedtime. For other purposes, it might be taken throughout the day, sometimes between meals to aid absorption. Individual responses can vary.
health_and_safety Safety & interactions
Combining L-tryptophan with antidepressant medications, particularly SSRIs, MAOIs, or tricyclics, can significantly increase serotonin levels, potentially leading to a serious condition called serotonin syndrome. It is crucial to consult a healthcare professional before combining these substances. Always seek medical advice regarding supplement and medication interactions.
Yes, L-Tryptophan can interact significantly with medications that affect serotonin levels, such as selective serotonin reuptake inhibitors (SSRIs), serotonin-norepinephrine reuptake inhibitors (SNRIs), and MAO inhibitors. Combining Tryptophan with these drugs can potentially lead to a serious condition called serotonin syndrome. It is crucial to consult a healthcare professional before taking L-Tryptophan if you are on any such medications.
Common side effects, especially at higher doses, can include mild gastrointestinal issues such as nausea, heartburn, stomach pain, and loss of appetite. Other potential effects might include drowsiness, dizziness, and dry mouth. It's generally well-tolerated when taken appropriately.
Yes, supplements that also influence serotonin levels, such as 5-HTP and St. John's Wort, should generally not be combined with L-tryptophan. This combination could also elevate the risk of serotonin syndrome. Always consult a healthcare provider for personalized advice on supplement stacking.
Individuals taking antidepressant medications (SSRIs, SNRIs, MAOIs), certain pain medications, or other drugs that affect serotonin should generally avoid L-Tryptophan due to the risk of serotonin syndrome. Pregnant or breastfeeding women, and those with pre-existing liver or kidney conditions, should also consult a healthcare provider before use. People with Eosinophilia-Myalgia Syndrome (EMS) history should also exercise caution.
Ingredients
| Ingredient | Amount per serving |
|---|---|
| L-Tryptophan | 500 mg |
Categories
Tryptophan 75.0
It's a strong, pure L-Tryptophan product but does not offer the best value or additional cofactors seen in some top-tier Tryptophan supplements.
Goals
Mood Support 80.0
The 500mg dosage is effective for supporting serotonin synthesis, a key neurotransmitter for mood regulation.
Stress Relief 80.0
By aiding serotonin production, this supplement consistently helps promote a sense of calm and contributes to stress reduction.
Sleep Support 80.0
As a precursor to melatonin, a 500mg dose of L-Tryptophan is commonly used and effective for improving sleep onset and quality for many users.
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