Reduced Glutathione 250 mg
Source Naturals
Reduced Glutathione 250 mg
4.6
★ ★ ★ ★ ★
(567 ratings)
Gluthathione 250 mg
Score 78.0
This product delivers a moderate 250mg dose of reduced L-Glutathione, directly targeting detoxification and antioxidant support. It's an affordable single-ingredient option, though the oral bioavailability of traditional glutathione is a known limitation.
Quantity: 60 Tablet(s)Servings size: 1 Tablet(s) (60 servings)
Selected goals:
Other goals:
Immunity
Anti-Aging
Detoxification
Skin Health
Anti-Inflammatory Support
leaderboard Score 78.0
This product delivers a moderate 250mg dose of reduced L-Glutathione, directly targeting detoxification and antioxidant support. It's an affordable single-ingredient option, though the oral bioavailability of traditional glutathione is a known limitation.
insights Analysis
Source Naturals Reduced Glutathione 250 mg is a focused supplement designed to provide a direct dose of L-Glutathione, the body's master antioxidant. At 250mg per serving, it offers a much more meaningful quantity than the nominal amounts present in multi-ingredient formulas, making it more relevant for individuals specifically targeting detoxification, anti-aging, or immune support through glutathione pathways. While 'reduced' indicates the active form, a widely acknowledged challenge with standard oral L-Glutathione is its relatively poor bioavailability, as it can be broken down in the digestive tract. This product is a cost-effective option for those who prefer a single-ingredient approach, but consumers seeking maximal absorption might consider more advanced forms like liposomal or S-acetyl glutathione.
- Provides a dedicated and more substantial dose of L-Glutathione (250mg) compared to multi-ingredient formulations.
- Relatively inexpensive per serving, making it an accessible option for regular glutathione supplementation.
- Contains 'reduced' glutathione, which is the active and bioavailable form within the body, if absorbed.
- Standard oral L-Glutathione has documented issues with bioavailability due to degradation in the digestive system, meaning a significant portion may not reach systemic circulation.
- Some individuals might require higher dosages (e.g., 500mg or more) for therapeutic effects, depending on their health goals.
- The inclusion of Calcium as dibasic calcium phosphate is an inactive ingredient, though generally benign.
- Individuals taking medications, especially chemotherapy, should consult a healthcare professional before supplementing with glutathione, as it might interact with certain treatments.
- While generally safe, some people may experience mild digestive upset.
$20.68($0.34 per serving)
 iHerb | $ 20.68 | |
 Vitacost | $ 23.09 | |
 Amazon | $ 27.98 |
bolt Effectiveness for goals
Yes, glutathione is often referred to as the "master antioxidant" due to its central role in neutralizing free radicals and regenerating other antioxidants like Vitamin C and E. It directly scavenges reactive oxygen species, protecting cells and tissues from oxidative damage. This is one of its most well-established functions.
Glutathione is a powerful antioxidant naturally produced in the body's cells, composed of three amino acids: glutamine, glycine, and cysteine. It plays a crucial role in detoxification, immune function, and protecting cells from oxidative damage. Levels of glutathione can decline due to aging, stress, and environmental toxins.
Glutathione is a powerful antioxidant naturally produced by the body, crucial for neutralizing free radicals and protecting cells from oxidative damage. It plays a key role in various metabolic processes and supports immune system function. It is also involved in detoxification by helping to eliminate harmful substances.
Some studies suggest that glutathione supplementation may contribute to skin brightening and a reduction in hyperpigmentation. This effect is thought to occur through its ability to inhibit melanin production and its antioxidant properties. However, more extensive research is needed to fully establish its efficacy for various skin concerns.
Glutathione is crucial for the body's detoxification system, particularly in the liver. It binds to toxins, heavy metals, and other harmful compounds, converting them into forms that can be more easily excreted from the body. This process helps protect cells from damage caused by these substances.
schedule Dosage, timing & forms
Recommended daily dosages for oral glutathione supplements can vary widely, often ranging from 250 mg to 1000 mg per day for adults. The appropriate dose may depend on the specific form, individual needs, and the advice of a healthcare professional.
Glutathione supplements are available in several forms to enhance absorption, including reduced L-glutathione (GSH), liposomal glutathione, and S-acetyl glutathione. Other delivery methods include topical creams, intravenous (IV) infusions, and nebulized forms. The best form often depends on individual needs and desired bioavailability.
Glutathione supplements come in various forms, including reduced L-glutathione, liposomal glutathione, S-acetyl glutathione, and topical creams. Intravenous (IV) administration is also an option, typically in clinical settings. Each form is designed to optimize absorption in the body.
Typical oral dosages for glutathione supplements can range from 250 mg to 1000 mg per day, depending on the specific form and individual needs. Some studies on skin brightening have used dosages around 500 mg daily. It's best to consult product labels or a healthcare professional for personalized guidance.
Liposomal glutathione encapsulates glutathione molecules within lipid spheres, which are believed to protect the glutathione from degradation in the digestive tract. This encapsulation aims to enhance its absorption and bioavailability compared to traditional reduced glutathione.
health_and_safety Safety & interactions
Glutathione is generally well-tolerated when taken orally. Some individuals may experience mild gastrointestinal discomfort such as abdominal cramps, bloating, or nausea. Allergic reactions like rashes are also possible, though rare.
Glutathione supplements are generally considered safe for most people when taken at recommended dosages. Potential mild side effects can include abdominal cramps, bloating, or allergic reactions like skin rashes in sensitive individuals. Rare cases of asthma exacerbation have been reported with inhaled glutathione.
While major drug interactions with glutathione are not widely documented, it is advisable to consult a healthcare professional if you are taking prescription medications. Glutathione's role in detoxification could theoretically influence the metabolism of certain drugs. This is especially important for those undergoing chemotherapy or taking immunosuppressants.
Individuals with asthma should exercise caution, as inhaled glutathione has been reported to trigger bronchospasm in some cases. People with known hypersensitivity or allergies to glutathione or its components should avoid taking it. Always consult a healthcare professional if you have pre-existing medical conditions before starting any new supplement.
While glutathione is generally well-tolerated, there is limited research on its interactions with specific medications. It is theoretically possible for glutathione to interact with chemotherapy drugs or immunosuppressants due to its role in cellular detoxification and immune modulation. Always consult a healthcare professional before combining glutathione with prescription medications, especially if you have chronic health conditions.
Ingredients
| Ingredient | Amount per serving |
|---|---|
| Calcium (Dibasic Calcium Phosphate) | 94 mg |
| L-Glutathione, Reduced | 250 mg |
Categories
Gluthathione 80.0
This product directly provides a substantial dose of reduced L-Glutathione, making it a dedicated source for those seeking to specifically supplement this compound. The score reflects its direct provision of glutathione but acknowledges the general bioavailability challenge of this form.
Goals
Immunity 80.0
Glutathione is a potent antioxidant and critical for immune cell function, directly supporting the body's defense mechanisms. The 250mg dose provides a good foundation, though bioavailability can limit its ultimate impact.
Anti-Aging 80.0
As the body's master antioxidant, glutathione plays a crucial role in combating oxidative stress and cellular damage, key factors in the aging process. Regular supplementation can support cellular longevity, assuming adequate absorption.
Detoxification 80.0
Glutathione is central to the body's detoxification pathways, particularly in the liver, by neutralizing toxins and supporting their elimination. A 250mg dose contributes to this process, though for intensive detoxification, higher doses or more bioavailable forms might be preferred.
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