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L-Glutathione (Reduced) 500 mg

California Gold Nutrition
4.6
★ ★ ★ ★ ★
(17143 ratings)
Gluthathione 500 mg
Product Image
Score84
A high-dose reduced-glutathione capsule with a long supply offers strong everyday value. Standard delivery and limited sourcing detail are the main compromises.
How scoring works
Quantity:120 Capsule(s) • (120 servings)
Goals:
Skin Health

Score 84

A high-dose reduced-glutathione capsule with a long supply offers strong everyday value. Standard delivery and limited sourcing detail are the main compromises.
How scoring works

Also available as

1 option
30 servings Gluthathione 500 mg • 30 Capsule(s) • 30 servings $12.05 ($0.40 per serving)
$42.34($0.35 per serving)
iHerb
$ 42.34
Amazon
$ 42.34
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Analysis

Reduced glutathione is clearly named at 500 mg, giving the formula strong dose and form transparency. The single-active capsule keeps the purpose focused and avoids low-dose padding.

Standard oral delivery is less protected than verified liposomal or acetylated formats, so individual absorption can vary. No branded source or purity standard is disclosed, which leaves sourcing confidence behind the otherwise clear label.

The long supply suits adults who want consistent antioxidant support and may appeal to skin-focused users. It remains narrower than a complete skin formula because collagen, hydration, and barrier-lipid pathways are not addressed.

Who is it for
  • Adults seeking high-dose reduced glutathione
  • Users who want a long-supply single-active product
  • Skin-focused users covering structural support elsewhere
Best for
  • Focused antioxidant routines
  • Clear reduced-form dosing
  • Long-term daily supplementation

Pros

  • Clearly identifies reduced glutathione
  • Provides 500 mg per serving
  • Large serving count
  • Single-active formula
  • Strong serving efficiency

Cons

  • No verified liposomal or acetylated delivery
  • No branded purity source
  • Absorption may vary with standard oral delivery
  • Does not address collagen or skin hydration

Nutrient quality

84 Highest impact

Reduced glutathione is the preferred redox form, though standard oral delivery lacks enhanced protection. The substantial reduced glutathione amount provides meaningful dose depth.

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Ingredient transparency

83 Highest impact

Every listed active ingredient has a specific amount. Usage and inactive-ingredient details remain incomplete.

.

Customer satisfaction

71 High impact

The average rating is positive but not exceptional. The very large feedback pool makes the average highly dependable.

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Value for money

98 Highest impact

The substantial reduced dose and large format strongly support the price. Long-term serving value is excellent for the disclosed dose.

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Goals

Skin Health
Skin Health
Impact
High effect
B Goal FitB+ Strength of SupportC- CoverageA+ Formula Quality
Gluthathione · 500 mg

Reduced glutathione provides direct antioxidant support and may help skin tone and oxidative resilience. Human evidence is promising but less established than the evidence for collagen peptides or vitamin C as structural support.

The capsule supplies a substantial, clearly labeled amount. Standard oral delivery is less dependable than verified liposomal or acetylated forms, which limits absorption confidence.

Study evidence
Gluthathione Supportive 13 studies

Ingredients

IngredientAmount per serving
L-Glutathione, Reduced
500 mg
Gluten Free Adults 18–50 Dairy Free
Report overview
Gluthathione · 500 mg OverallScore77
D- Active Ingredient Quality & BioavailabilityA+ Dose, Safety & Label TransparencyA+ Value

Reduced glutathione is supplied at a strong direct dose with clear single-capsule labeling. Standard oral delivery is less absorbable than acetylated or verified liposomal forms, and no branded purity source is named. Its low serving cost creates excellent value for a high-dose reduced formula.

View ingredientView products
Loading alternative details
84 Performance

L-Glutathione (Reduced) 500 mg

California Gold Nutrition
<p>Its label clearly provides 500 mg of L-Glutathione, making it a more clearly defined glutathione option. Compared with the original, its ingredient and goal alignment is stronger, although the input does not provide independent testing or absorption evidence.</p>
76 Performance

Reduced Glutathione 250 mg

Source Naturals
<p>Its label clearly provides 250 mg of L-Glutathione, Reduced, making it a more clearly defined glutathione option. Compared with the original, its ingredient and goal alignment is stronger, although the input does not provide independent testing or absorption evidence.</p>
74 Performance

Optimal Liposomal Glutathione Plus

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<p>Its label clearly provides 350 mg of L-Glutathione, making it a more clearly defined glutathione option. Compared with the original, its ingredient and goal alignment is stronger, although the input does not provide independent testing or absorption evidence.</p>
79 Budget

Glutathione 500 mg

Nutricost
<p>Its label clearly provides 500 mg of L-Glutathione, preserving relevant glutathione coverage. Compared with the original, it lowers the serving cost, although the input does not provide independent testing or absorption evidence.</p>
76 Budget

L-Glutathione 500 mg

AN Amazing Nutrition Amazing Formulas
<p>Its label clearly provides 500 mg of L-Glutathione, preserving relevant glutathione coverage. Compared with the original, it lowers the serving cost, although the input does not provide independent testing or absorption evidence.</p>
73 Budget

Chem-Defense Orange Flavored

Source Naturals
<p>Its label clearly provides 50 mg of L-Glutathione, preserving relevant glutathione coverage. Compared with the original, it lowers the serving cost, although the input does not provide independent testing or absorption evidence.</p>
72 Value

L-Glutathione 100 mg

Bluebonnet
<p>Its label clearly provides 100 mg of L-Glutathione, Reduced, keeping the formula relevant to glutathione. Compared with the original, the somewhat higher serving cost and ingredient detail create a useful quality-to-cost balance, although the input does not provide independent testing or absorption evidence.</p>
79 Value

Mega-Liposomal Glutathione+ 750 mg Organic Fruit Flavor

Aurora NutraScience
<p>Its label clearly provides 750 mg of L-Glutathione, keeping the formula relevant to glutathione. Compared with the original, the somewhat higher serving cost and ingredient detail create a useful quality-to-cost balance, although the input does not provide independent testing or absorption evidence.</p>
75 Value

Reduced Glutathione Complex 50 mg Orange Flavored

Source Naturals
<p>Its label clearly provides 50 mg of L-Glutathione, keeping the formula relevant to glutathione. Compared with the original, the lower serving cost and ingredient detail create a useful quality-to-cost balance, although the input does not provide independent testing or absorption evidence.</p>
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Sources

Published studies used for the product analysis and the top-ranked studies for each ingredient and goal.

  1. The effects of the oral supplementation of L-Cystine associated with reduced L-Glutathione-GSH on human skin pigmentation: a randomized, double-blinded, benchmark- and placebo-controlled clinical trial.
    Duperray J; Sergheraert R; Chalothorn K; Tachalerdmanee P; Perin F · Journal of cosmetic dermatology · 2022
    Randomized trial124 participantsSkin Health forGluthathione
  2. Skin-whitening and skin-condition-improving effects of topical oxidized glutathione: a double-blind and placebo-controlled clinical trial in healthy women.
    Watanabe F; Hashizume E; Chan GP; Kamimura A · Clinical, cosmetic and investigational dermatology · 2014
    Randomized trial30 participantsSkin Health forGluthathione
  3. Systematic Review of the Efficacy and Safety of Topical Glutathione in Dermatology.
    Khanna R; Rambhia P; Chapas A · The Journal of clinical and aesthetic dermatology · 2025
    Systematic review5 studies pooledSkin Health forGluthathione
  4. Effects of antioxidants on glutathione levels and clinical recovery from the malnutrition syndrome kwashiorkor--a pilot study.
    Becker K; Pons-Kühnemann J; Fechner A; Funk M; Gromer S; Gross HJ; Grünert A; Schirmer RH · Redox report : communications in free radical research · 2006
    Randomized trialSkin Health forGluthathione
  5. Glutathione and its antiaging and antimelanogenic effects.
    Weschawalit S; Thongthip S; Phutrakool P; Asawanonda P · Clinical, cosmetic and investigational dermatology · 2020
    Randomized trial57 participantsSkin Health forGluthathione