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DefensePlus

NutriBiotic
4.8
★ ★ ★ ★ ★
(5493 ratings)
Ginger
Maitake Mushroom 50 mg
Astragalus 100 mg
Reishi mushroom 100 mg
Shiitake Mushroom 50 mg
Product Image
Score73
Strong convenience and full amount disclosure support this broad seasonal blend, while modest unstandardized botanicals limit focused effects.
How scoring works
Quantity:90 Tablet(s) • (90 servings)
Goals:

Score 73

Strong convenience and full amount disclosure support this broad seasonal blend, while modest unstandardized botanicals limit focused effects.
How scoring works

Also available as

1 option
45 servings 1 Tablet(s) • 45 Tablet(s) • 45 servings $13.12 ($0.29 per serving)
$22.25($0.24 per serving)
iHerb
$ 22.49
Vitacost
$ 22.49
Amazon
$ 22.25
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Analysis

Grapefruit seed extract leads the blend, supported by vitamin C, zinc, astragalus, and reishi. Every active amount is visible, which makes the busy formula easier to assess.

Ginger, maitake, shiitake, echinacea, Oregon grape, and yarrow appear at modest amounts. The label does not state extract ratios or active markers for these supporting botanicals.

A one-tablet serving and ninety-day supply provide better routine value than the smaller presentation. The formula suits broad seasonal supplementation rather than concentrated mushroom or ginger use.

Who is it for
  • Adults wanting a long-supply immune blend
  • People who prefer one tablet daily
Best for
  • Routine seasonal supplementation
  • Vitamin C and zinc plus botanicals

Pros

  • Ninety one-tablet servings
  • Vitamin C and zinc are included
  • Every botanical amount is stated
  • Grapefruit seed extract has the lead amount

Cons

  • Mushroom extracts are lightly dosed
  • No active-marker standardization
  • Astragalus form details are incomplete
  • Broad formula favors breadth over potency

Warnings

  • Grapefruit seed extract may interact with medicines affected by grapefruit-sensitive metabolism.
  • Echinacea can trigger allergy symptoms in people sensitive to ragweed-family plants.
  • Medicinal mushrooms may conflict with immunosuppressant therapy by influencing immune activity.

Nutrient quality

69 High impact

A coherent immune theme and safe core nutrients provide basic quality. Missing standardization and many lightly dosed botanicals make the formula shallow and padding-prone.

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Ingredient transparency

77 High impact

Every active amount is explicit without a proprietary blend. Missing potency markers, timing, and excipient details limit the usefulness of that disclosure.

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Customer satisfaction

73 High impact

The aggregate rating is very favorable, but it provides no specific experience evidence. The very large review count gives the broad signal a useful volume base, while no detailed feedback supports taste, tolerance, or recurring-problem assessment.

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Value for money

75 High impact

A long supply and low relative serving cost provide good practical value. Shallow botanical dosing remains the main category weakness.

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Ingredients

IngredientAmount per serving
Vitamin C (Meta-C)
 125 mg
Zinc (Zinc Gluconate)
 5 mg
Grapefruit seed extract
250 mg
Astragalus
100 mg
Reishi Mushroom Extract
100 mg
Echinacea angustifolia extract
50 mg
Ginger root extract
50 mg
Maitake Mushroom Extract
50 mg
Oregon grape
50 mg
Shiitake Mushroom Extract
50 mg
Yarrow extract
50 mg
Gluten Free Adults 18–50 Vegan Dairy Free Women Children 4+ Vegetarian
Report overview
Ginger · 50 mg OverallScore45
D- Active Ingredient Quality & BioavailabilityD Dose, Safety & Label TransparencyD+ Value

The label identifies ginger root extract but gives no extract ratio or gingerol standardization. Naming the root improves botanical specificity, while the extraction method remains unknown. The dose is low, though the inexpensive serving partly limits the value concern.

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Maitake Mushroom · 50 mg OverallScore41
F Active Ingredient Quality & BioavailabilityC- Dose, Safety & Label TransparencyB- Value

The low-cost serving includes a clearly stated amount of Maitake extract. Potency remains limited because the amount is low and the mushroom part, extraction method, and active markers are not disclosed. It fits better as a broad multi-ingredient immune formula than as a concentrated Maitake supplement.

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Astragalus · 100 mg OverallScore36
F Active Ingredient Quality & BioavailabilityB- Dose, Safety & Label TransparencyF Value

The disclosed amount is clear, but the label does not identify a root extract, species, or active marker. No organic or other purity claim is provided, and additive quality cannot be checked from the available label data. Cost per standardized extract equivalent is high for such limited form detail.

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79 Performance

Shiitake Maitake 250 mg

Nature's Way
Clearly dosed maitake and shiitake extracts provide a concise alternative to the original’s lightly dosed multi-botanical blend. Polysaccharides are named, but mushroom parts, extraction method, and beta-glucan yield remain missing.
79 Performance

M/R/S Mushroom Formula

Pure Encapsulations
Equal amounts of maitake, reishi, and shiitake fruiting-body extracts provide stronger mushroom-part disclosure and focused coverage. Extraction method and beta-glucan yield are still unknown, and the formula omits vitamin C, zinc, ginger, and astragalus.
79 Performance

Reishi Shiitake Maitake Mushroom Extract

Solgar
Organic reishi, shiitake, and maitake extracts provide a focused mushroom blend, with extra reishi marker details improving confidence. Maitake and shiitake remain modest, while mushroom parts and extraction methods are unclear.
79 Budget

Rei-Shi Mushrooms 270 mg

NOW
Reishi powder and extract with shiitake provide focused mushroom coverage at lower serving cost than the broad immune blend. Missing fruiting-body, extraction-ratio, and standardization details limit confidence in potency.
72 Budget

Immune Action

NaturesPlus
Astragalus, shiitake, echinacea, schisandra, and ligustrum preserve a broad botanical immune strategy at lower serving cost. Most amounts are modest and the label lacks plant parts, extract details, and active-marker standardization.
73 Budget

Mushroom Immune Complex with Maitake Reishi & Shiitake

Solaray
Maitake, reishi, and shiitake provide a coherent mushroom formula with favorable serving economics and disclosed species. Repeated entries make totals less clear, while mushroom parts, extraction, and beta-glucans are missing.
76 Value

Immune Essentials Comprehensive Formula

Swanson
Larch arabinogalactan, bovine colostrum, oat beta-glucan, elderberry, maitake, and shiitake provide broad immune coverage with good serving value. The mushrooms are lightly dosed and bovine colostrum makes the formula unsuitable for people with a milk allergy.
72 Value

Beyond Wellness

KAL
Buffered vitamin C, zinc picolinate, echinacea, standardized andrographis, elderberry, astragalus, and mushrooms create broad immune support with clearer marker disclosure. Many mushroom and herbal additions are modest, but the core actives provide reasonable effective value.
75 Value

Brain & Body

Host Defense MycoBotanicals
Substantial lion’s mane plus turmeric, reishi, ginger, cinnamon, and black pepper provide broader mushroom and botanical depth than the original’s many small additions. Active-marker and processing details are limited, but the disclosed amounts support fair value for broad use.
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