Product Image

DefensePlus

NutriBiotic
4.8
★ ★ ★ ★ ★
(5406 ratings)
Ginger
Maitake Mushroom 50 mg
Astragalus 100 mg
Reishi mushroom 100 mg
Shiitake Mushroom 50 mg
Product Image
Score96

A high-value bulk bottle for broad-spectrum daily immune and wellness support.

How scoring works
Quantity:90 Tablet(s) • (90 servings)
Goals:

Score 96

A high-value bulk bottle for broad-spectrum daily immune and wellness support.

How scoring works

Also available as

1 option
45 servings 1 Tablet(s) • 45 Tablet(s) • 45 servings $13.12 ($0.29 per serving)
$22.25($0.24 per serving)
iHerb
$ 22.49
Vitacost
$ 22.49
Amazon
$ 22.49
Report prices

Analysis

This bulk size is ideal for families or individuals who want to maintain their immune health consistently over the long term. The formula covers many bases by combining grapefruit seed extract with traditional herbs like astragalus and echinacea.

Each tablet is packed with different botanical extracts that support your body's natural defenses. It's a sturdy, well-reviewed option that focuses on variety and affordability.

Pros

  • Excellent price for 90 servings
  • Broad mix of 11 active ingredients
  • Includes reishi and maitake mushrooms
  • Simple once-daily dosage

Cons

  • Tablet size may be an issue for some
  • Contains ginger which some find spicy
  • Includes many small-dose ingredients

Warnings

  • Consult a professional if pregnant
  • Take with food to prevent stomach upset
  • Keep bottle tightly sealed

Nutrient quality

91 Highest impact

Broad-spectrum complex featuring eleven concentrated extracts provides multi-faceted immune support. Synergistic botanical and fungal levels are appropriately balanced for systemic resilience.

Ingredient transparency

99 Highest impact

Labeling is exceptionally detailed, Quantification the milligram Weights for each botanical in the complex. Full transparency levels allow users to precisely evaluate the dosage of all eleven actives.

Customer satisfaction

97 Highest impact

Exceptional average ratings confirm high efficacy for seasonal and acute immune support. High reliability across thousands of reviews indicates high consumer consensus on performance.

Value for money

97 Highest impact

This larger bottle count provides outstanding affordability for a complex multi-herb immune responder. The price per serving is exceptional for the variety and dose of active extracts provided.

Report analysis

Ingredients

IngredientAmount per serving
Vitamin C (Meta-C)
 125 mg
Zinc (Zinc Gluconate)
 5 mg
Grapefruit seed extract
250 mg
Astragalus
100 mg
Reishi Mushroom Extract
100 mg
Echinacea angustifolia extract
50 mg
Ginger root extract
50 mg
Maitake Mushroom Extract
50 mg
Oregon grape
50 mg
Shiitake Mushroom Extract
50 mg
Yarrow extract
50 mg
Gluten Free Adults 18–50 Vegan Dairy Free Women Children 4+ Vegetarian
Report overview
Ginger · 50 mg OverallScore78
D Active Ingredient Quality & BioavailabilityA+ Dose, Safety & Label TransparencyA+ Value
This immune support supplement provides an effective dose of ginger root extract alongside botanical and fungal extracts. Its concentrated form and competitive pricing make it a high-value option for those looking to include ginger in their wellness routine.
View ingredientView products
Maitake Mushroom · 50 mg OverallScore57
F Active Ingredient Quality & BioavailabilityC- Dose, Safety & Label TransparencyA+ Value
This immune support complex contains 50mg of Maitake extract, which is at the low end of the potency scale. While the use of an extract is good for absorption, the dosage is likely too small for significant standalone Maitake benefits.
View ingredientView products
Astragalus · 100 mg OverallScore47
F Active Ingredient Quality & BioavailabilityB Dose, Safety & Label TransparencyF Value
This multi-herb tablet is designed for supportive immune care with a focus on grapefruit seed and Astragalus. It is a cost-effective way to get a wide variety of extracts in a single serving.
View ingredientView products
88 Value

Immune Support

NaturesPlus
4.8
★★★★★
(279 ratings)
Combinations of astragalus, maitake mushroom, and andrographis support broad immune resilience. Bioavailable zinc bisglycinate provides foundational support for metabolic and antioxidant health during seasonal demand.
Other sellers (2)
92 Value

Pure Defense Mushroom-8 Immune Support

Irwin Naturals
4.5
★★★★★
(291 ratings)
Meaningful doses of eight organic mushrooms and essential oils provide comprehensive support for resilience. High label transparency allows for full awareness of the weights for each botanical component used.
Other sellers (3)
92 Value

Beyond Wellness

KAL
4.8
★★★★★
(176 ratings)
Vitamin C and zinc are paired with standardized andrographolides for consistent potency. This multi-herb approach appears well-aligned for holistic wellness and maintaining health during seasonal changes.
Other sellers (1)
92 Performance

Wellness Formula

Source Naturals
4.8
★★★★★
(4830 ratings)
High-potency Vitamin C and zinc ascorbate provide robust seasonal support for defense mechanisms. Multi-layered botanical support from propolis, andrographis, and garlic targets several systemic pathways for better resilience.
Other sellers (1)
91 Performance

Global Wellness Immuno-Shield with Elderberry

Irwin Naturals
4.6
★★★★★
(175 ratings)
Essential oils and organic mushroom powders provide deep support for maintaining immune health. This formula uses liquid softgels to deliver elderberry and astragalus extracts more efficiently for systemic resilience.
Other sellers (2)
94 Performance

Leaky Gut Formula

Codeage
4.8
★★★★★
(4201 ratings)
Intestinal lining support from L-glutamine and zinc l-carnosine is essential for long-term immune wellness. Probiotics and medicinal mushrooms like maitake contribute to a healthy microbiome and gut barrier function.
Other sellers (5)
96 Budget

DefensePlus

NutriBiotic
4.9
★★★★★
(4211 ratings)
Grapefruit seed, astragalus, and reishi extracts support immune defense through multiple pathways. This formula assists in maintaining resilience during seasonal changes with consistent levels of echinacea and ginger.
Other sellers (1)
92 Budget

Beyond Wellness

KAL
4.8
★★★★★
(176 ratings)
Potassium ascorbate provides a high dose of Vitamin C combined with zinc and olive leaf for general health. Extracts of elderberry and garlic provide additional supportive layers for maintaining wellness.
Other sellers (1)
87 Budget

Immune Support System

Pure Essence
4.7
★★★★★
(111 ratings)
Spirulina and bovine colostrum are paired with a variety of mushrooms like shiitake and turkey tail for broad defense. This system is designed for individuals seeking multifaceted botanical support for a resilient immune response.
Other sellers (1)
88 Value

Immune Support

NaturesPlus
4.8
★★★★★
(279 ratings)
Combinations of astragalus, maitake mushroom, and andrographis support broad immune resilience. Bioavailable zinc bisglycinate provides foundational support for metabolic and antioxidant health during seasonal demand.
Other sellers (2)
92 Value

Pure Defense Mushroom-8 Immune Support

Irwin Naturals
4.5
★★★★★
(291 ratings)
Meaningful doses of eight organic mushrooms and essential oils provide comprehensive support for resilience. High label transparency allows for full awareness of the weights for each botanical component used.
Other sellers (3)
92 Value

Beyond Wellness

KAL
4.8
★★★★★
(176 ratings)
Vitamin C and zinc are paired with standardized andrographolides for consistent potency. This multi-herb approach appears well-aligned for holistic wellness and maintaining health during seasonal changes.
Other sellers (1)
92 Performance

Wellness Formula

Source Naturals
4.8
★★★★★
(4830 ratings)
High-potency Vitamin C and zinc ascorbate provide robust seasonal support for defense mechanisms. Multi-layered botanical support from propolis, andrographis, and garlic targets several systemic pathways for better resilience.
Other sellers (1)
91 Performance

Global Wellness Immuno-Shield with Elderberry

Irwin Naturals
4.6
★★★★★
(175 ratings)
Essential oils and organic mushroom powders provide deep support for maintaining immune health. This formula uses liquid softgels to deliver elderberry and astragalus extracts more efficiently for systemic resilience.
Other sellers (2)
94 Performance

Leaky Gut Formula

Codeage
4.8
★★★★★
(4201 ratings)
Intestinal lining support from L-glutamine and zinc l-carnosine is essential for long-term immune wellness. Probiotics and medicinal mushrooms like maitake contribute to a healthy microbiome and gut barrier function.
Other sellers (5)
Report alternatives