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DefensePlus

NutriBiotic
4.9
★ ★ ★ ★ ★
(4211 ratings)
Ginger
Maitake Mushroom 50 mg
Astragalus 100 mg
Reishi mushroom 100 mg
Shiitake Mushroom 50 mg
Product Image
Score96

A comprehensive daily tablet featuring GSE, astragalus, and mushrooms for immune support.

How scoring works
Quantity:45 Tablet(s) • (45 servings)
Goals:

Score 96

A comprehensive daily tablet featuring GSE, astragalus, and mushrooms for immune support.

How scoring works

Also available as

1 option
90 servings 1 Tablet(s) • 90 Tablet(s) • 90 servings $22.25 ($0.24 per serving)
$13.12($0.29 per serving)
iHerb
$ 9.18
Amazon
$ 13.49
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Analysis

This formula packs in a lot of variety, including grapefruit seed extract, astragalus, and various mushroom extracts. These ingredients are frequently used to support a healthy immune response and overall systemic resilience.

With added zinc and vitamin C, it provides the basic building blocks for immune health alongside more specialized botanical support. It’s a smart choice for people who want a broad-spectrum daily support tablet.

Pros

  • Broad variety of 11 active ingredients
  • Good value for a complex formula
  • Includes both minerals and herbs
  • Simple once-daily tablet

Cons

  • Tablets can be large
  • Many ingredients are at lower doses
  • Echinacea is not suitable for everyone

Warnings

  • Consult a professional if you have an autoimmune condition
  • May cause mild stomach upset if taken on empty stomach
  • Keep in a dry place

Nutrient quality

91 Highest impact

Wide array of concentrated botanical and fungal extracts provides broad immune pathway support. Dosages are moderate but synergistically aligned for comprehensive seasonal wellness.

Ingredient transparency

99 Highest impact

Full milligram Weights for each of the eleven active components are clearly Quantification. High transparency levels allow users to accurately assess the dose of every botanical in the complex.

Customer satisfaction

98 Highest impact

Exceptional average rating across thousands of reviews confirms the product's effectiveness for immune defense. High reliability is evident from the consistent positive user reports.

Value for money

97 Highest impact

Outstanding affordability for a complex eleven-ingredient immune responder makes this an excellent value choice. The low price per serving makes high-quality multi-botanical support highly accessible.

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Ingredients

IngredientAmount per serving
Vitamin C (Meta-C)
 125 mg
Zinc (Zinc Gluconate)
 5 mg
Grapefruit seed extract
250 mg
Astragalus
100 mg
Reishi Mushroom Extract
100 mg
Echinacea angustifolia extract
50 mg
Ginger root extract
50 mg
Maitake Mushroom Extract
50 mg
Oregon grape
50 mg
Shiitake Extract
50 mg
Yarrow extract
50 mg
Gluten Free Adults 18–50 Dairy Free Children 4+
Report overview
Ginger · 50 mg OverallScore76
C+ Active Ingredient Quality & BioavailabilityB+ Dose, Safety & Label TransparencyB+ Value
This multi-ingredient defense tablet includes a concentrated ginger root extract for added therapeutic support. It is a well-formulated and cost-efficient supplement for immune and digestive wellness.
View ingredientView products
Maitake Mushroom · 50 mg OverallScore57
F Active Ingredient Quality & BioavailabilityC- Dose, Safety & Label TransparencyA+ Value
This formula contains a low 50mg dose of Maitake extract alongside several other immune-supporting ingredients. While the extraction process aids bioavailability, the dosage is too low to provide the primary benefits typically associated with Maitake.
View ingredientView products
Astragalus · 100 mg OverallScore47
F Active Ingredient Quality & BioavailabilityB Dose, Safety & Label TransparencyF Value
This formula offers a broad variety of herbs and nutrients to support the body's natural defenses. It is a cost-effective way to get multiple supportive ingredients in a single tablet.
View ingredientView products
88 Value

Immune Support

NaturesPlus
4.8
★★★★★
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Significant doses of astragalosides and andrographolides support broad immune resilience and cell activity. Inclusion of zinc bisglycinate provides foundational support for metabolic and antioxidant status.
Other sellers (2)
92 Value

Pure Defense Mushroom-8 Immune Support

Irwin Naturals
4.5
★★★★★
(291 ratings)
Eight organic mushroom powders are combined with essential oils and elderberry for deep immune support. High label transparency for primary active components ensures a reliable choice for maintaining resilience.
Other sellers (3)
92 Value

Beyond Wellness

KAL
4.8
★★★★★
(176 ratings)
Standardized extracts of andrographis and astragalus are paired with 1000 mg of Vitamin C for seasonal wellness. This formula role in promoting general resilience is reflected in its diverse blend of botanical markers.
Other sellers (1)
92 Performance

Wellness Formula

Source Naturals
4.8
★★★★★
(4830 ratings)
Potent doses of 2,600 mg of Vitamin C and zinc ascorbate provide powerful support for seasonal immune resilience. Multilayered botanical support from andrographis, garlic, and propolis targets numerous systemic defense pathways.
Other sellers (1)
91 Performance

Global Wellness Immuno-Shield with Elderberry

Irwin Naturals
4.6
★★★★★
(175 ratings)
Essential oils and botanical extracts are delivered in a liquid softgel for multi-faceted immune support. Individual weights for active components like elderberry and reishi reflect a high standard for resilience and wellness.
Other sellers (2)
94 Performance

Leaky Gut Formula

Codeage
4.8
★★★★★
(4201 ratings)
L-glutamine and zinc l-carnosine support the integrity of the intestinal lining, which is crucial for immune health. Probiotics like saccharomyces boulardii contribute to maintaining a healthy gut barrier and inflammatory balance.
Other sellers (5)
96 Budget

DefensePlus

NutriBiotic
4.8
★★★★★
(5406 ratings)
This larger bottle count provides the same blend of grapefruit seed and astragalus at a lower price per serving. Standardized extracts of reishi and echinacea ensure consistent potency for seasonal immune maintenance.
Other sellers (2)
92 Budget

Beyond Wellness

KAL
4.8
★★★★★
(176 ratings)
High doses of Vitamin C and zinc are combined with garlic and olive leaf extract for broad immune wellness. Modest dosages of elderberry and mushrooms provide secondary support within this multi-nutrient profile.
Other sellers (1)
87 Budget

Immune Support System

Pure Essence
4.7
★★★★★
(111 ratings)
A wide array of medicinal mushrooms like cordyceps and reishi offer broad immune system resilience. Botanical extracts including astragalus and andrographis contribute to multifaceted defense and overall vitality.
Other sellers (1)
88 Value

Immune Support

NaturesPlus
4.8
★★★★★
(279 ratings)
Significant doses of astragalosides and andrographolides support broad immune resilience and cell activity. Inclusion of zinc bisglycinate provides foundational support for metabolic and antioxidant status.
Other sellers (2)
92 Value

Pure Defense Mushroom-8 Immune Support

Irwin Naturals
4.5
★★★★★
(291 ratings)
Eight organic mushroom powders are combined with essential oils and elderberry for deep immune support. High label transparency for primary active components ensures a reliable choice for maintaining resilience.
Other sellers (3)
92 Value

Beyond Wellness

KAL
4.8
★★★★★
(176 ratings)
Standardized extracts of andrographis and astragalus are paired with 1000 mg of Vitamin C for seasonal wellness. This formula role in promoting general resilience is reflected in its diverse blend of botanical markers.
Other sellers (1)
92 Performance

Wellness Formula

Source Naturals
4.8
★★★★★
(4830 ratings)
Potent doses of 2,600 mg of Vitamin C and zinc ascorbate provide powerful support for seasonal immune resilience. Multilayered botanical support from andrographis, garlic, and propolis targets numerous systemic defense pathways.
Other sellers (1)
91 Performance

Global Wellness Immuno-Shield with Elderberry

Irwin Naturals
4.6
★★★★★
(175 ratings)
Essential oils and botanical extracts are delivered in a liquid softgel for multi-faceted immune support. Individual weights for active components like elderberry and reishi reflect a high standard for resilience and wellness.
Other sellers (2)
94 Performance

Leaky Gut Formula

Codeage
4.8
★★★★★
(4201 ratings)
L-glutamine and zinc l-carnosine support the integrity of the intestinal lining, which is crucial for immune health. Probiotics like saccharomyces boulardii contribute to maintaining a healthy gut barrier and inflammatory balance.
Other sellers (5)
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