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SelenoExcell Selenium 200 mcg

Natural Factors
4.8
★ ★ ★ ★ ★
(2418 ratings)
Selenium 200 mcg
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Score86
A focused, clearly dosed selenium supplement using selenium yeast. It offers good value, but the substantial amount should not be casually stacked.
How scoring works
Quantity:90 Capsule(s) • (90 servings)
Goals:
General Health
Immunity

Score 86

A focused, clearly dosed selenium supplement using selenium yeast. It offers good value, but the substantial amount should not be casually stacked.
How scoring works
$9.77($0.10 per serving)
Vitacost
$ 9.77
Amazon
$ 9.77
iHerb
$ 9.77
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Analysis

The single active provides 200 mcg of selenium, a substantial supplemental amount that supports antioxidant enzymes and normal thyroid function. Selenium yeast generally provides organic selenium, though its exact selenium compounds are not identified.

A one-ingredient formula is easy to fit around other supplements and avoids unrelated actives. The yeast source can contain a mixture of organic selenium compounds, but their proportions are not shown.

One capsule per serving keeps use simple, and good value strengthens the practical case. The amount is high enough that overlap with multivitamins and other selenium products needs attention.

Who is it for
  • Adults specifically seeking selenium support
  • People who prefer a simple single-active formula
Best for
  • Targeted selenium intake
  • Antioxidant-enzyme support
  • Filling a known selenium gap

Pros

  • Uses selenium yeast
  • Clearly discloses the 200 mcg amount
  • Simple one-capsule serving
  • Offers good value

Cons

  • Provides only one nutrient
  • Amount may be unnecessary for people with adequate selenium intake
  • Exact selenium compounds are not identified

Warnings

  • Two hundred micrograms is a substantial amount, so it should not be combined casually with another selenium supplement or a high-selenium multivitamin.
  • Chronic excess selenium can cause brittle hair or nails, nausea, or a garlic-like breath odor; these signs warrant stopping use and seeking advice.
  • People already being treated for a thyroid disorder should account for total selenium intake with their clinician rather than adding a high-dose product automatically.

Nutrient quality

90 Highest impact

SelenoExcell is a clearly identified high-selenium yeast with strong food-form quality. The selenium amount remains below the adult upper limit but requires accounting for other selenium sources.

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Ingredient transparency

83 Highest impact

The selenium amount and source are clearly stated. Complete directions and inactive ingredients are not supplied.

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Customer satisfaction

73 High impact

The supplied aggregate rating indicates very strong customer satisfaction. Specific comments are unavailable, so complaint patterns and intended-use fit cannot be verified.

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Value for money

97 Highest impact

A recognized yeast source and low serving cost create excellent value. The simple formula compares strongly within the category.

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Report analysis

Goals

General Health
Impact
Highest effect
A- Goal FitA- Strength of SupportC- CoverageA+ Formula Quality
Selenium · 200 mcg

Selenium yeast supplies an essential trace mineral for antioxidant enzymes and thyroid-related functions. The substantial amount can support selenium status when dietary intake is low.

The single-mineral design is narrow, and the yeast source is less chemically specific than L-selenomethionine. The amount leaves limited room for additional selenium supplements, so stacking should be avoided.

Study evidence
Selenium Supportive 70 studies
Immunity
Impact
High effect
B+ Goal FitB+ Strength of SupportD+ CoverageA Formula Quality
Selenium · 200 mcg

Selenium supports antioxidant enzymes and normal immune-cell function at a substantial amount. The single active is fully disclosed and directly relevant to oxidative-stress control.

The yeast source may provide organic selenium, but the precise selenium species is not stated. Coverage remains narrow because no barrier nutrients or other direct immune actives are included.

Study evidence
Selenium Mixed 37 studies

Ingredients

IngredientAmount per serving
Selenium (Saccharomyces cerevisiae)
200 mcg
Gluten Free Adults 18–50 Dairy Free Sugar Free
Report overview
A Active Ingredient Quality & BioavailabilityA+ Dose, Safety & Label TransparencyA+ Value

The 200 mcg serving matches the commonly studied target for selenium support. SelenoExcell provides a high-selenium yeast matrix with strong food-form quality. The trademarked SelenoExcell source is clearly identified on the product label. The full selenium dose costs very little compared with the collection benchmark.

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Sources

Published studies used for the product analysis and the top-ranked studies for each ingredient and goal.

  1. Associations of selenium status with all-cause and cause-specific mortality: a systematic review and meta-analysis of cohort studies.
    Cui Z; Xie R; Lu X; Schomburg L; Brenner H; Schöttker B · Redox biology · 2025
    Meta-analysis95 participants20 studies pooledGeneral Health forSelenium
  2. Dietary Antioxidants, Circulating Antioxidant Concentrations, Total Antioxidant Capacity, and Risk of All-Cause Mortality: A Systematic Review and Dose-Response Meta-Analysis of Prospective Observational Studies.
    Jayedi A; Rashidy-Pour A; Parohan M; Zargar MS; Shab-Bidar S · Advances in nutrition (Bethesda, Md.) · 2019
    Meta-analysis507,251 participants41 studies pooledGeneral Health forSelenium
  3. The efficacy and safety of selenium supplementation versus placebo in the treatment of Graves' orbitopathy: A systematic review and meta-analysis of randomised controlled trials.
    Sharabati I; Qafesha RM; Hindawi MD; Amro S; Ayesh BM · Clinical endocrinology · 2024
    Meta-analysis4 studies pooledGeneral Health forSelenium
  4. Associations of plasma metal concentrations with the risks of all-cause and cardiovascular disease mortality in Chinese adults.
    Shi L; Yuan Y; Xiao Y; Long P; Li W; Yu Y; Liu Y; Liu K; Wang H; Zhou L; Yang H; Li X; He M; Wu T · Environment international · 2021
    Cohort study6,155 participantsGeneral Health forSelenium
  5. Updates on clinical studies of selenium supplementation in radiotherapy.
    Puspitasari IM; Abdulah R; Yamazaki C; Kameo S; Nakano T; Koyama H · Radiation oncology (London, England) · 2015
    Systematic review16 studies pooledGeneral Health forSelenium
  6. Effects of selenium supplementation on selenoprotein gene expression and response to influenza vaccine challenge: a randomised controlled trial.
    Goldson AJ; Fairweather-Tait SJ; Armah CN; Bao Y; Broadley MR; Dainty JR; Furniss C; Hart DJ; Teucher B; Hurst R · PloS one · 2011
    Randomized trial119 participantsImmunity forSelenium
  7. Effect of selenium on immune response against hepatitis B vaccine with accelerated method in insulin-dependent diabetes mellitus patients.
    Janbakhsh A; Mansouri F; Vaziri S; Sayad B; Afsharian M; Rahimi M; Shahebrahimi K; Salari F · Caspian journal of internal medicine · 2013
    Randomized trial62 participantsImmunity forSelenium
  8. Chemoprevention trial of human hepatitis with selenium supplementation in China.
    Yu SY; Li WG; Zhu YJ; Yu WP; Hou C · Biological trace element research · 1990
    Non-randomized trial20,847 participantsImmunity forSelenium
  9. Selenium nanoparticles as adjunctive therapy in sepsis: A pilot randomized clinical trial.
    Gu WJ; Huang W; Zhao FZ; Yuan XK; Jin K; Chen JL; Zhang CY; Huang Y; He L; Zhuang H; Yin HY; Chen T · Drug resistance updates : reviews and commentaries in antimicrobial and anticancer chemotherapy · 2026
    Randomized trial70 participantsImmunity forSelenium
  10. Selenium supplementation in patients with autoimmune thyroiditis decreases thyroid peroxidase antibodies concentrations.
    Gärtner R; Gasnier BC; Dietrich JW; Krebs B; Angstwurm MW · The Journal of clinical endocrinology and metabolism · 2002
    Randomized trial70 participantsImmunity forSelenium