L-Arginine + L-Citrulline 750 mg
Nutricost
L-Arginine + L-Citrulline 750 mg
4.7
★ ★ ★ ★ ★
(1239 ratings)
Citrulline 250 mg
Arginine 500 mg
Score 75.0
An extremely cost-effective L-Arginine and L-Citrulline supplement, offering great value for consistent nitric oxide support despite modest per-serving dosages.
Quantity: 240 Capsule(s)Servings size: 1 Capsule(s) (240 servings)
Selected goals:
Other goals:
Fitness
Muscle Gain
Cardiovascular Support
leaderboard Score 75.0
An extremely cost-effective L-Arginine and L-Citrulline supplement, offering great value for consistent nitric oxide support despite modest per-serving dosages.
insights Analysis
This Nutricost product provides a combination of 500mg L-Arginine and 250mg L-Citrulline per serving, totaling 750mg of active compounds. Its major advantage is its exceptional value, offering a very low price per serving compared to similar products on the market. While the individual dosages are modest compared to quantities used in some clinical studies for peak performance, it serves as a highly cost-effective option for consistent, daily supplementation to support nitric oxide pathways. Online reviews frequently highlight the brand's affordability and commitment to basic, effective formulations.
- Offers an incredibly low price per serving, making it one of the most cost-effective options for L-Arginine and L-Citrulline.
- The combination of both amino acids supports dual pathways for nitric oxide production.
- Comes in a large quantity (240 servings), providing a long-lasting supply for consistent daily use.
- The individual dosages of L-Arginine (500mg) and L-Citrulline (250mg) per capsule are relatively low, meaning multiple capsules are often needed to reach doses recommended for significant performance benefits.
- The L-Citrulline is not in the more researched L-Citrulline Malate form, which some users prefer for enhanced athletic performance.
- For individuals needing higher doses, taking multiple capsules might be less convenient than a higher-potency single-dose supplement.
- Individuals with very low blood pressure should consult a healthcare professional before use due to the vasodilating effects of nitric oxide boosters.
- If you are on prescription medications, especially for blood pressure or heart conditions, discuss supplementation with a doctor to avoid potential interactions.
$17.95($0.07 per serving)
 iHerb | $ 17.95 |
bolt Effectiveness for goals
Yes, L-Citrulline supplementation can lead to higher and more sustained plasma L-Arginine levels than Arginine supplementation alone. This is because Citrulline bypasses intestinal and liver metabolism, being efficiently converted to Arginine in the kidneys. This indirect pathway can more effectively increase nitric oxide production.
L-Citrulline is often considered more effective at increasing sustained L-Arginine and nitric oxide levels in the body than L-Arginine itself. This is because L-Citrulline bypasses significant metabolism in the gut and liver, converting to L-Arginine more efficiently in the kidneys. This leads to a more pronounced and prolonged increase in circulating L-Arginine.
L-Citrulline is converted to L-Arginine in the kidneys, which then increases nitric oxide production. This can lead to enhanced blood flow to muscles during exercise, potentially reducing fatigue and improving endurance. It's particularly studied for high-intensity activities and resistance training.
Combining L-Arginine and L-Citrulline may offer enhanced and more sustained nitric oxide production. L-Citrulline can recycle back into L-Arginine, creating a continuous supply for nitric oxide synthesis. This combined approach could potentially lead to greater and longer-lasting effects on blood flow compared to taking either supplement alone.
L-Citrulline is converted to L-Arginine in the body, leading to increased nitric oxide production. This can help improve blood flow to muscles during exercise, potentially enhancing endurance and reducing fatigue. Studies have shown L-Citrulline to be effective in improving performance in both aerobic and anaerobic exercises.
schedule Dosage, timing & forms
Yes, Arginine and Citrulline can be taken together, and some individuals choose to combine them. Citrulline is converted to Arginine in the body, which can effectively increase Arginine levels. Taking them together may offer a synergistic approach, potentially providing both immediate and sustained benefits.
Citrulline is generally considered more effective at increasing and sustaining blood Arginine levels when taken orally. This is because Arginine itself undergoes significant breakdown in the gut and liver (first-pass metabolism) before reaching systemic circulation. Citrulline bypasses this metabolism and is efficiently converted to Arginine in the kidneys.
For exercise performance, dosages of L-Citrulline typically range from 6 to 8 grams per day. If using Citrulline Malate (often a 2:1 ratio of Citrulline to Malate), a common dose is 8 to 12 grams, providing an equivalent amount of L-Citrulline. For general cardiovascular support, lower doses around 3-4 grams may be suggested.
For exercise performance, typical dosages are 6 to 8 grams of L-Citrulline, or 8 to 12 grams of Citrulline Malate. Citrulline Malate is often a 2:1 ratio (6-8g L-Citrulline). It's generally recommended to take it about 60 minutes before physical activity.
When combining them, it's generally recommended to start with conservative doses for each. Since Citrulline effectively raises Arginine levels, you might consider slightly lower individual Arginine doses than if taking it alone. Monitoring your body's response is key to finding the optimal combined dosage.
health_and_safety Safety & interactions
Yes, L-Arginine and L-Citrulline can generally be taken together. L-Citrulline is a precursor to L-Arginine, and combining them may lead to sustained increases in nitric oxide levels. However, potential additive effects on blood pressure should be considered.
Yes, L-Arginine can interact with medications for blood pressure, erectile dysfunction (e.g., sildenafil), and nitrates, potentially causing blood pressure to drop too low. It may also interact with blood thinners and diabetes medications. Consulting a healthcare professional is crucial, especially if taking other medications.
Common side effects of L-Arginine can include abdominal pain, bloating, diarrhea, and nausea, especially at higher doses. These effects are generally mild and temporary. Individuals may also experience a drop in blood pressure.
L-Citrulline is generally well-tolerated, but some individuals may experience mild gastrointestinal discomfort, such as nausea or diarrhea. These side effects are more likely at higher doses. It can also potentially lower blood pressure.
Yes, L-Arginine can interact with medications for high blood pressure. Because L-Arginine can lower blood pressure, taking it with antihypertensive drugs might cause blood pressure to drop too low. It is advisable to consult a healthcare professional before combining them.
Ingredients
| Ingredient | Amount per serving |
|---|---|
| L-Arginine | 500 mg |
| L-Citrulline | 250 mg |
Categories
Arginine 75.0
Offers a good amount of L-Arginine per serving at an exceptionally low price, providing excellent value for arginine supplementation.
Citrulline 70.0
Delivers L-Citrulline at a very attractive price per serving, making it a cost-effective option for consistent citrulline intake, though not in the malate form.
Goals
The very low price per serving makes it a strong contender for long-term, economical daily cardiovascular support through nitric oxide pathways, contributing to overall circulatory health.
Fitness 68.0
While individual doses are moderate, its low price per serving allows users to take multiple capsules more economically to approach dosages that could support workout performance and pumps.
Muscle Gain 65.0
Provides an affordable way to support blood flow for nutrient delivery to muscles, offering a cost-effective background supplement for those pursuing muscle gain, although direct impact on hypertrophy is limited.
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