Published studies used for the product analysis and the top-ranked studies for each ingredient and goal.
- Folic Acid Supplementation and the Risk of Cardiovascular Diseases: A Meta-Analysis of Randomized Controlled Trials.
Li Y; Huang T; Zheng Y; Muka T; Troup J; Hu FB · Journal of the American Heart Association · 2018
Meta-analysis82,334 participants30 studies pooledflagHeart Health forscienceFolate
- Intake of vitamin B6, folate, and vitamin B12 and risk of coronary heart disease: a systematic review and dose-response meta-analysis of prospective cohort studies.
Jayedi A; Zargar MS · Critical reviews in food science and nutrition · 2020
Meta-analysis369,746 participants11 studies pooledflagHeart Health forscienceVitamin B12
- A comprehensive investigation of biochemical status in patients with telogen effluvium: Analysis of Hb, ferritin, vitamin B12, vitamin D, thyroid function tests, zinc, copper, biotin, and selenium levels.
Durusu Turkoglu IN; Turkoglu AK; Soylu S; Gencer G; Duman R · Journal of cosmetic dermatology · 2024
Case-control study180 participantsflagHair Health forscienceVitamin B12
- Trace element levels in alopecia areata.
Bhat YJ; Manzoor S; Khan AR; Qayoom S · Indian journal of dermatology, venereology and leprology · 2009
Case-control study100 participantsflagHair Health forscienceCopper
- Comparative Analysis of Postoperative Hair Loss and Micronutrient Deficiencies After One-Anastomosis Gastric Bypass Versus Sleeve Gastrectomy.
Chinisaz F; Maleki T; Najjari K; Miratashi Yazdi SA · Obesity surgery · 2026
Cohort study261 participantsflagHair Health forscienceFolate flagHair Health forscienceIron
- Subclinical atherosclerosis and impaired cardiac autonomic control in pediatric patients with Vitamin B12 deficiency.
Celik SF; Celik E · Nigerian journal of clinical practice · 2018
Case-control study100 participantsflagHeart Health forscienceVitamin B12
- MTHFR 677C-->T polymorphism and risk of coronary heart disease: a meta-analysis.
Klerk M; Verhoef P; Clarke R; Blom HJ; Kok FJ; Schouten EG; MTHFR Studies Collaboration Group · JAMA · 2002
Meta-analysis23,920 participants40 studies pooledflagHeart Health forscienceFolate
- Retrospective Review of 2851 Female Patients With Telogen Effluvium: A Single-Center Experience.
Karakoyun Ö; Ayhan E; Yıldız İ · Journal of cosmetic dermatology · 2025
Cohort study2,851 participantsflagHair Health forscienceVitamin B12
- UV damage to hair and the effect of antioxidants and metal chelators.
Millington KR; Marsh JM · International journal of cosmetic science · 2021
In vitro / ex vivo studyflagHair Health forscienceCopper
- Twelve weeks of protracted venous infusion of fluorouracil (5-FU) is as effective as 6 months of bolus 5-FU and folinic acid as adjuvant treatment in colorectal cancer.
Saini A; Norman AR; Cunningham D; Chau I; Hill M; Tait D; Hickish T; Iveson T; Lofts F; Jodrell D; Ross PJ; Oates J · British journal of cancer · 2003
Randomized trialflagHair Health forscienceFolate
- Nonlinear associations of serum cobalamin with risk of all-cause and cardiovascular mortality in hypertensive adults.
Zhu X; Tang Y; Cheang I; Gao R; Liao S; Yao W; Zhou Y; Zhang H; Li X · Hypertension research : official journal of the Japanese Society of Hypertension · 2023
Cohort study9,934 participantsflagHeart Health forscienceVitamin B12
- Dietary Intake and Plasma Concentration of B Vitamins in Relation to Incident Coronary Artery Disease in African-American Adults: The Jackson Heart Study.
Huo C; Thiagarajah K; Tekwe CD; Tucker KL; Bidulescu A · The Journal of nutrition · 2026
Cohort study4,906 participantsflagHeart Health forscienceFolate
- Hair Loss After Metabolic and Bariatric Surgery: a Systematic Review and Meta-analysis.
Zhang W; Fan M; Wang C; Mahawar K; Parmar C; Chen W; Yang W; Global Bariatric Research Collaborative · Obesity surgery · 2021
Meta-analysis2,538 participants18 studies pooledflagHair Health forscienceFolate
- Quantitative Analysis of Selected Circulating Hematological Biomarkers, Essential Minerals, Vitamins, and Thyroid Hormones in Females Affected by Hair Loss.
Al-Fawaeir S; Al-Odat I · Diseases (Basel, Switzerland) · 2025
Case-control study200 participantsflagHair Health forscienceVitamin B12 flagHair Health forscienceFolate
- Menkes disease and response to copper histidine: An Indian case series.
Yoganathan S; Sudhakar SV; Arunachal G; Thomas M; Subramanian A; George R; Danda S · Annals of Indian Academy of Neurology · 2022
Case series4 participantsflagHair Health forscienceCopper
- Folic Acid Therapy Reduces the First Stroke Risk Associated With Hypercholesterolemia Among Hypertensive Patients.
Qin X; Li J; Spence JD; Zhang Y; Li Y; Wang X; Wang B; Sun N; Chen F; Guo J; Yin D; Sun L; Tang G; He M; Fu J; Cai Y; Shi X; Ye P; Chen H; Zhao S; Chen M; Gao C; Kong X; Hou FF; Huang Y; Huo Y · Stroke · 2017
Randomized trial20,702 participantsflagHeart Health forscienceFolate
- Methylmalonic acid, vitamin B12, and mortality risk in patients with preexisting coronary heart disease: a prospective cohort study.
Guo J; Liu X; Wang Z; Lu R; Liu Y; Zhang Y; Tian W; Fang S; Wang S; Yu B · Nutrition journal · 2023
Cohort study1,755 participantsflagHeart Health forscienceVitamin B12
- Micronutrient levels and thyroid functions in scarring alopecias: Do they play a role in disease pathogenesis?
Gönülal Bak R; Çetin C; Kılınç F; Akbaş A; Aksoy Saraç G · Cutaneous and ocular toxicology · 2025
Case-control study136 participantsflagHair Health forscienceVitamin B12
- Preserving fibre health: reducing oxidative stress throughout the life of the hair fibre.
Marsh JM; Davis MG; Lucas RL; Reilman R; Styczynski PB; Li C; Mamak M; McComb DW; Williams RE; Godfrey S; Navqi KR; Chechik V · International journal of cosmetic science · 2016
In vitro / ex vivo studyflagHair Health forscienceCopper
- Beneficial effects of folic acid supplementation on lipid markers in adults: A GRADE-assessed systematic review and dose-response meta-analysis of data from 21,787 participants in 34 randomized controlled trials.
Asbaghi O; Ashtary-Larky D; Bagheri R; Nazarian B; Pourmirzaei Olyaei H; Rezaei Kelishadi M; Nordvall M; Wong A; Dutheil F; Naeini AA · Critical reviews in food science and nutrition · 2022
Meta-analysis21,787 participants34 studies pooledflagHeart Health forscienceFolate
- Vitamin B12 deficiency is associated with cardiovascular autonomic neuropathy in patients with type 2 diabetes.
Hansen CS; Jensen JS; Ridderstråle M; Vistisen D; Jørgensen ME; Fleischer J · Journal of diabetes and its complications · 2018
Cross-sectional study469 participantsflagHeart Health forscienceVitamin B12
- Factors Associated with Premature Hair Graying in a Young Indian Population.
Chakrabarty S; Krishnappa PG; Gowda DG; Hiremath J · International journal of trichology · 2016
Case-control study74 participantsflagHair Health forscienceVitamin B12
- Serum ferritin and vitamin D levels should be evaluated in patients with diffuse hair loss prior to treatment.
Tamer F; Yuksel ME; Karabag Y · Postepy dermatologii i alergologii · 2023
Case-control study109 participantsflagHair Health forscienceFolate
- A Meta-Analysis of Folic Acid in Combination with Anti-Hypertension Drugs in Patients with Hypertension and Hyperhomocysteinemia.
Wang WW; Wang XS; Zhang ZR; He JC; Xie CL · Frontiers in pharmacology · 2020
Meta-analysis7,887 participants65 studies pooledflagHeart Health forscienceFolate
- Effects of 2-year vitamin B12 and folic acid supplementation in hyperhomocysteinemic elderly on arterial stiffness and cardiovascular outcomes within the B-PROOF trial.
van Dijk SC; Enneman AW; Swart KM; van Wijngaarden JP; Ham AC; Brouwer-Brolsma EM; van der Zwaluw NL; Blom HJ; Feskens EJ; Geleijnse JM; van Schoor NM; Dhonukshe-Rutten RA; de Jongh RT; Lips P; de Groot LC; Uitterlinden AG; Smulders YM; van den Meiracker AH; Mattace Raso FU; van der Velde N · Journal of hypertension · 2016
Randomized trial2,919 participantsflagHeart Health forscienceVitamin B12
- Hair Loss After Laparoscopic Sleeve Gastrectomy.
Katsogridaki G; Tzovaras G; Sioka E; Perivoliotis K; Zachari E; Magouliotis D; Tasiopoulou V; Chatedaki C; Zacharoulis D · Obesity surgery · 2019
Cohort study50 participantsflagHair Health forscienceVitamin B12
- Phase I-II study of vinorelbine in combination with 5-fluorouracil and folinic acid as first-line chemotherapy in metastatic breast cancer: a regimen with a low subjective toxic burden.
Nolè F; de Braud F; Aapro M; Minchella I; De Pas TM; Zampino MG; Monti S; Andreoni G; Goldhirsch A · Annals of oncology : official journal of the European Society for Medical Oncology · 1997
Randomized trialflagHair Health forscienceFolate
- Folate Biomarkers, Folate Intake, and Risk of Death From All Causes, Cardiovascular Disease, and Cancer: A Systematic Review and Dose-Response Meta-Analysis of Prospective Cohort Studies.
Fallah M; Karim Dehnavi M; Lotfi K; Aminianfar A; Azadbakht L; Esmaillzadeh A · Nutrition reviews · 2025
Meta-analysis423,304 participants25 studies pooledflagHeart Health forscienceFolate
- Evaluating treatment options for cardiovascular autonomic neuropathy in patients with diabetes mellitus: a systematic review.
Goh JK; Koh L · Diabetology international · 2024
Systematic review724 participants13 studies pooledflagHeart Health forscienceVitamin B12
- Dermatological findings of vitamin B12 deficiency and resolving time of these symptoms.
Demir N; Doğan M; Koç A; Kaba S; Bulan K; Ozkol HU; Doğan SZ · Cutaneous and ocular toxicology · 2014
Single-arm trial57 participantsflagHair Health forscienceVitamin B12
- Sequential administration of cyclophosphamide, methotrexate, 5-fluorouracil, and folinic acid as salvage treatment in metastatic breast cancer.
Pronzato P; Amoroso D; Ardizzoni A; Bertelli G; Canobbio L; Conte PF; Cusimano MP; Fusco V; Gulisano M; Lionetto R · American journal of clinical oncology · 1987
Randomized trialflagHair Health forscienceFolate
- Efficacy of folic acid supplementation on endothelial function and plasma homocysteine concentration in coronary artery disease: A meta-analysis of randomized controlled trials.
Yi X; Zhou Y; Jiang D; Li X; Guo Y; Jiang X · Experimental and therapeutic medicine · 2021
Meta-analysis377 participantsflagHeart Health forscienceFolate
- Vitamin B12 Status and Cardiovascular Risk: Novel Insights from NMR-Based Lipoprotein Profiling in 20,665 Adults.
Eken Y; Tekin N; Şahin F; Tay İ; Yıldırım Saral N; Serteser M; Baykal AT · Journal of clinical medicine · 2026
Cross-sectional study20,665 participantsflagHeart Health forscienceVitamin B12
- Risk Factors for Pediatric Alopecia Areata: Clinical and Biochemical Findings from a Case - Control Study.
İritaş SY · Dermatology practical & conceptual · 2026
Case-control study600 participantsflagHair Health forscienceVitamin B12
- Factors Associated with the Severity of Female Pattern Hair Loss: A Retrospective Study.
Jian M; Zhang D; Fu X; Cheng Y; Sun X; Wang Z; Li L · Aesthetic plastic surgery · 2026
Observational study289 participantsflagHair Health forscienceFolate
- Periconception Red Blood Cell Folate and Offspring Congenital Heart Disease : Nested Case-Control and Mendelian Randomization Studies.
Chen H; Zhang Y; Wang D; Chen X; Li M; Huang X; Jiang Y; Dou Y; Wang Y; Ma X; Sheng W; Jia B; Yan W; Huang G; SPCC (Shanghai Preconception Cohort) Group · Annals of internal medicine · 2022
Case-control study985 participantsflagHeart Health forscienceFolate
- Methylmalonic acid and vitamin B12 in patients with heart failure.
Polytarchou K; Dimitroglou Y; Varvarousis D; Christodoulis N; Psachoulia C; Pantziou C; Mourouzis I; Pantos C; Manolis AS · Hellenic journal of cardiology : HJC = Hellenike kardiologike epitheorese · 2021
Case-control study156 participantsflagHeart Health forscienceVitamin B12
- Demographic Characteristics and Association of Serum Vitamin B12, Ferritin and Thyroid Function with Premature Canities in Indian Patients from an Urban Skin Clinic of North India: A Retrospective Analysis of 71 Cases.
Sonthalia S; Priya A; Tobin DJ · Indian journal of dermatology · 2022
Cross-sectional study71 participantsflagHair Health forscienceVitamin B12
- A phase II study of paclitaxel, weekly, 24-hour continous infusion 5-fluorouracil, folinic acid and cisplatin in patients with advanced gastric cancer.
Kollmannsberger C; Quietzsch D; Haag C; Lingenfelser T; Schroeder M; Hartmann JT; Baronius W; Hempel V; Clemens M; Kanz L; Bokemeyer C · British journal of cancer · 2000
Observational studyflagHair Health forscienceFolate
- MTHFR and risk of stroke and heart disease in a low-folate population: a prospective study of 156 000 Chinese adults.
Bennett DA; Parish S; Millwood IY; Guo Y; Chen Y; Turnbull I; Yang L; Lv J; Yu C; Davey Smith G; Wang Y; Wang Y; Peto R; Collins R; Walters RG; Li L; Chen Z; Clarke R; China Kadoorie Biobank (CKB) Study Collaborative Group · International journal of epidemiology · 2023
Cohort study156,253 participantsflagHeart Health forscienceFolate
- Vitamin B12 and folate status in early pregnancy and cardiometabolic risk factors in the offspring at age 5-6 years: findings from the ABCD multi-ethnic birth cohort.
Krikke GG; Grooten IJ; Vrijkotte TG; van Eijsden M; Roseboom TJ; Painter RC · BJOG : an international journal of obstetrics and gynaecology · 2016
Cohort study1,950 participantsflagHeart Health forscienceVitamin B12
- Micronutrient Deficiencies and Digital Computerized Phototrichogram Analysis in Telogen Effluvium: a Retrospective Correlation Study in a Tertiary Medical Center.
Arslan H; Gündüz Ö · Dermatology practical & conceptual · 2023
Observational study973 participantsflagHair Health forscienceVitamin B12
- Continuous infusion of a large dose of CF (folinic acid) and 5-FU combined with CDDP in the treatment of advanced esophageal cancer.
Zhu ZQ; Zhu ZA; Cai HX · International journal of clinical pharmacology and therapeutics · 2017
Observational studyflagHair Health forscienceFolate
- Role of oxaliplatin combined with 5-fluorouracil and folinic acid in the first- and second-line treatment of advanced colorectal cancer.
Jonker D; Rumble RB; Maroun J; Gastrointestinal Cancer Disease Site Groupof Cancer Care Ontario’s Program in Evidence-Based Care · Current oncology (Toronto, Ont.) · 2012
Randomized trialflagHair Health forscienceFolate
- The Association Between Alopecia Areata and Iron Deficiency Anemia: A Large-Scale Population-Based Case-Control Study.
Davidovici B; Drutin Y; Ben-Tov A; Mimouni D; Wohl Y · Journal of personalized medicine · 2026
Case-control study100,203 participantsflagHair Health forscienceIron
- Iron Deficiency and Nonscarring Alopecia in Women: Systematic Review and Meta-Analysis.
Treister-Goltzman Y; Yarza S; Peleg R · Skin appendage disorders · 2022
Meta-analysis10,029 participants36 studies pooledflagHair Health forscienceIron
- Assessment of Serum Ferritin Levels in Female Patients With Telogen Effluvium.
Thamotharan N; Harikumar MV; Sundaram M; Swaminathan A; Rangarajan S · Cureus · 2026
Cross-sectional study100 participantsflagHair Health forscienceIron
- Diagnosis and treatment of female alopecia: Focusing on the iron deficiency-related alopecia.
Lin CS; Chan LY; Wang JH; Chang CH · Tzu chi medical journal · 2023
Cohort study155 participantsflagHair Health forscienceIron
- Topical tretinoin for hair growth promotion.
Bazzano GS; Terezakis N; Galen W · Journal of the American Academy of Dermatology · 1986
Non-randomized trial56 participantsflagHair Health forscienceVitamin A
- A review of isotretinoin in the treatment of frontal fibrosing alopecia.
Shahpar A; Nezhad NZ; Sahaf AS; Ahramiyanpour N · Journal of cosmetic dermatology · 2024
Systematic review232 participants15 studies pooledflagHair Health forscienceVitamin A
- Efficacy of Isotretinoin and Acitretin in Treatment of Frontal Fibrosing Alopecia: Retrospective Analysis of 54 Cases.
Rakowska A; Gradzińska A; Olszewska M; Rudnicka L · Journal of drugs in dermatology : JDD · 2018
Cohort study54 participantsflagHair Health forscienceVitamin A
- Systemic Treatments for Lichen Planopilaris and Frontal Fibrosing Alopecia: A Retrospective Study of 315 Patients.
Willaert M; Van Dongen T; Dikrama P; Nijsten T; Hijnen D; Waalboer-Spuij R · Acta dermato-venereologica · 2025
Cohort study315 participantsflagHair Health forscienceVitamin A
- Tretinoin enhances minoxidil response in androgenetic alopecia patients by upregulating follicular sulfotransferase enzymes.
Sharma A; Goren A; Dhurat R; Agrawal S; Sinclair R; Trüeb RM; Vañó-Galván S; Chen G; Tan Y; Kovacevic M; Situm M; McCoy J · Dermatologic therapy · 2020
Single-arm trialflagHair Health forscienceVitamin A