Grapeseed Extract 100 mg
Life Extension
Grapeseed Extract 100 mg
Resveratrol 20 mg
Score 65.0
A supplement combining a moderate dose of Vitamin C with a modest amount of trans-resveratrol and a proprietary grapeseed blend for general antioxidant support.
Quantity: 60 Capsule(s) • (60 servings)
Goals:
Heart Health
Anti-Aging
Cardiovascular Support
Anti-Inflammatory Support
Score 65.0
A supplement combining a moderate dose of Vitamin C with a modest amount of trans-resveratrol and a proprietary grapeseed blend for general antioxidant support.
Analysis
This Life Extension product focuses primarily on Grapeseed Extract (implied by the name and proprietary blend, though the quantity is for the blend), but also includes 40mg of Trans-Resveratrol (20mg from Japanese Knotweed and 20mg from Grape fruit extract). The addition of 250mg of Vitamin C is a positive for general antioxidant support. However, 40mg of resveratrol is on the lower side for significant effects, and the 'Proprietary Blend' of Grapeseed Extract makes it difficult to assess the exact quantity of active flavonoid compounds. It's a decent antioxidant supplement, but perhaps not the strongest choice if high-dose resveratrol is the primary goal.
Pros
- Includes a decent dose of Vitamin C (250mg) for additional antioxidant benefits.
- Contains Trans-Resveratrol from two sources, enhancing its spectrum.
- Life Extension is a reputable brand known for research-backed formulations.
Cons
- The 40mg combined Trans-Resveratrol dose is relatively low for pronounced benefits.
- Utilizes a 'Proprietary Blend' for Grapeseed Extract, obscuring specific active ingredient amounts.
- Price per serving is relatively high for the resveratrol dosage provided.
Warnings
- Consumers should be aware that the primary resveratrol dose is modest.
$26.25($0.43 per serving)
 Pure Formulas | $ 26.25 | |
 iHerb | $ 26.25 | |
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 Amazon | $ 26.25 |
Effectiveness for goals
Some research suggests Resveratrol may contribute to heart health by improving blood vessel function and reducing oxidative stress. However, human studies have shown mixed results, and more research is needed to confirm these benefits.
Early laboratory and animal studies indicate Resveratrol might activate pathways associated with aging and cellular health. Evidence for these effects in humans for anti-aging is currently limited and requires further investigation.
Resveratrol is generally associated with antioxidant, anti-inflammatory, and cardioprotective properties based on preclinical and some human studies. These broad effects are thought to contribute to its potential overall health support.
Resveratrol possesses antioxidant properties, which means it can help protect cells from damage caused by free radicals. This cellular protection is one of its most studied mechanisms.
Some preclinical studies suggest Resveratrol may have neuroprotective effects and support cognitive function by reducing inflammation and oxidative stress in the brain. Human research on these specific benefits is ongoing but still limited.
Dosage, timing & forms
Doses often range from 250 mg to 1000 mg per day, though some studies have explored higher amounts. The appropriate dosage can vary based on individual needs and specific health goals. It is advisable to consult a healthcare professional for personalized guidance.
There is no universally established "best" time to take Resveratrol. Some individuals prefer to take it with meals to enhance absorption, especially if the supplement contains fat-soluble compounds. Consistency in timing, such as taking it at the same time daily, may be more important than the specific time of day.
Taking Resveratrol with a meal, particularly one containing some fat, may improve its absorption. Resveratrol is fat-soluble, and dietary fats can help with its bioavailability. However, some formulations are designed for enhanced absorption and may not strictly require food.
There is no official daily recommended dietary allowance (RDA) for Resveratrol. While studies have explored dosages up to several grams per day with varying results regarding safety and efficacy, very high doses may be associated with increased risk of side effects. It is best to adhere to the dosage instructions provided by the manufacturer or consult a healthcare professional.
Resveratrol is commonly available in capsule and tablet forms. It can also be found in powders, liquids, and topical applications. Most supplements contain `trans-resveratrol`, which is considered the most biologically active form.
Safety & interactions
Yes, resveratrol may have anti-platelet effects and could potentially increase the risk of bleeding when taken with anticoagulant or antiplatelet medications. It is advisable to consult a healthcare professional before combining them. Monitoring by a physician is recommended to adjust medication dosages if necessary.
Resveratrol is generally well-tolerated at typical doses. Some individuals might experience mild gastrointestinal issues such as nausea, diarrhea, or abdominal discomfort. These effects are usually temporary and diminish with continued use or a lower dose.
Due to its potential anti-platelet effects, resveratrol may increase the risk of bleeding during and after surgery. It is generally recommended to discontinue resveratrol supplements at least two weeks before any scheduled surgical procedure. Always inform your surgeon and anesthesiologist about all supplements you are taking.
There is insufficient reliable evidence regarding the safety of resveratrol supplementation during pregnancy or breastfeeding. Therefore, it is generally advised to avoid its use during these periods. Always consult with a healthcare provider before taking any supplements if pregnant or nursing.
Resveratrol can inhibit certain cytochrome P450 enzymes (e.g., CYP3A4, CYP2C9) in the liver, which are responsible for metabolizing many drugs. This inhibition could potentially alter the effectiveness or increase the side effects of medications processed by these enzymes. It is important to discuss all current medications with a healthcare provider before starting resveratrol.
Ingredients
| Ingredient | Amount per serving |
|---|---|
Vitamin C | 250 mg |
Calcium | 25 mg |
Proprietary Blend | 100 mg |
Trans-Resveratrol | 20 mg |
Adults 18–50
Report overviewCategories
Resveratrol 65.0
While it contains resveratrol and other beneficial compounds, its lower resveratrol dosage and proprietary blend nature make it less focused as a dedicated resveratrol product within the collection.
Goals
Heart Health 65.0
The combination of resveratrol, grape extract (including grapeseed in the blend), and Vitamin C provides a good range of antioxidants beneficial for cardiovascular protection and endothelial health, despite the moderate resveratrol dose.
Anti-Aging 60.0
The 40mg resveratrol, though trans-form, is a lower dose for significant anti-aging effects. The added Vitamin C and grape seed extract contribute to overall antioxidant defense, but a stronger resveratrol focus would be ideal.
Skin Health 60.0
Antioxidants like resveratrol and Vitamin C are crucial for skin health by protecting against oxidative damage, though a higher resveratrol concentration might offer more targeted benefits for aging skin concerns.
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