Published studies used for the product analysis and the top-ranked studies for each ingredient and goal.
- Efficacy and Safety of Topical or Oral Hydrolyzed Collagen in Women with Dermatoporosis: A Randomized, Double-Blind, Factorial Design Study.
Guadanhim LRS; Miot HA; Soares JLM; Silva SAM; Leonardi GR; Lopes RD; Bagatin E · Dermatology and therapy · 2023
Randomized trial56 participantsflagSkin Health forscienceCollagen
- The Sustained Effects of Bioactive Collagen Peptides on Skin Health: A Randomized, Double-Blind, Placebo-Controlled Clinical Study.
Wang Y; Zhu W; Luo W; Ma Y; Zhou Y · Journal of cosmetic dermatology · 2025
Randomized trial77 participantsflagSkin Health forscienceCollagen
- Exploring the Impact of Hydrolyzed Collagen Oral Supplementation on Skin Rejuvenation: A Systematic Review and Meta-Analysis.
Dewi DAR; Arimuko A; Norawati L; Yenny SW; Setiasih NL; Perdiyana A; Arkania N; Nadhira F; Wiliantari N · Cureus · 2024
Meta-analysis967 participants14 studies pooledflagSkin Health forscienceCollagen
- Effects of collagen-based supplements on skin's hydration and elasticity: A systematic review and meta-analysis.
Danessa G; Notario D; Regina R · Indian journal of dermatology, venereology and leprology · 2025
Meta-analysis646 participants10 studies pooledflagSkin Health forscienceCollagen
- Oral intake of specific bioactive collagen peptides reduces skin wrinkles and increases dermal matrix synthesis.
Proksch E; Schunck M; Zague V; Segger D; Degwert J; Oesser S · Skin pharmacology and physiology · 2014
Randomized trial114 participantsflagSkin Health flagAnti-Aging forscienceCollagen
- Oral Supplementation of Low-Molecular-Weight Collagen Peptides Reduces Skin Wrinkles and Improves Biophysical Properties of Skin: A Randomized, Double-Blinded, Placebo-Controlled Study.
Kim J; Lee SG; Lee J; Choi S; Suk J; Lee JH; Yang JH; Yang JS; Kim J · Journal of medicinal food · 2022
Randomized trial100 participantsflagSkin Health forscienceCollagen
- Oral supplementation of specific collagen peptides has beneficial effects on human skin physiology: a double-blind, placebo-controlled study.
Proksch E; Segger D; Degwert J; Schunck M; Zague V; Oesser S · Skin pharmacology and physiology · 2014
Randomized trial69 participantsflagSkin Health flagAnti-Aging forscienceCollagen
- Oral intake of collagen peptide NS improves hydration, elasticity, desquamation, and wrinkling in human skin: a randomized, double-blinded, placebo-controlled study.
Lee M; Kim E; Ahn H; Son S; Lee H · Food & function · 2023
Randomized trial100 participantsflagSkin Health flagAnti-Aging forscienceCollagen
- Oral Intake of Low-Molecular-Weight Collagen Peptide Improves Hydration, Elasticity, and Wrinkling in Human Skin: A Randomized, Double-Blind, Placebo-Controlled Study.
Kim DU; Chung HC; Choi J; Sakai Y; Lee BY · Nutrients · 2018
Randomized trial64 participantsflagSkin Health forscienceCollagen
- Effects of Oral Collagen for Skin Anti-Aging: A Systematic Review and Meta-Analysis.
Pu SY; Huang YL; Pu CM; Kang YN; Hoang KD; Chen KH; Chen C · Nutrients · 2023
Meta-analysis1,721 participants26 studies pooledflagSkin Health forscienceCollagen
- Effects of hydrolyzed collagen supplementation on skin aging: a systematic review and meta-analysis.
de Miranda RB; Weimer P; Rossi RC · International journal of dermatology · 2021
Meta-analysis1,125 participants19 studies pooledflagAnti-Aging flagSkin Health forscienceCollagen
- Skin Anti-Aging and Moisturizing Effects of Low-Molecular-Weight Collagen Peptide Supplementation in Healthy Adults: A Randomized, Double-Blind, Placebo-Controlled Clinical Trial.
Lee E; Ahn DK; Kim JH; Lee S; Kim HJ; Lee HK; Shin JH · Journal of microbiology and biotechnology · 2025
Randomized trial70 participantsflagAnti-Aging forscienceCollagen
- Study on the Multiple Efficacies of Vitamin C Serum in Anti-Glycation, Anti-Carbonylation, Antioxidation, and Anti-Inflammation of Human Skin Based on In Vivo Tests.
Zi Y; Liu J; Liu Q; Pan Y; Jiang X · Journal of cosmetic dermatology · 2026
Randomized trial66 participantsflagAnti-Aging forscienceVitamin C
- Evaluation of the anti-wrinkle effect of a lipophilic pro-vitamin C derivative, tetra-isopalmitoyl ascorbic acid.
Yokota M; Yahagi S · Journal of cosmetic dermatology · 2022
Randomized trial69 participantsflagAnti-Aging forscienceVitamin C
- The role of vitamin C in pushing back the boundaries of skin aging: an ultrasonographic approach.
Crisan D; Roman I; Crisan M; Scharffetter-Kochanek K; Badea R · Clinical, cosmetic and investigational dermatology · 2015
Clinical trial60 participantsflagAnti-Aging forscienceVitamin C
- In vivo evaluation of topical ascorbic acid application on skin aging by 50 MHz ultrasound.
Vergilio MM; Aiello LM; Furlan AS; Caritá AC; Azevedo JR; Bolzinger MA; Chevalier Y; Leonardi GR · Journal of cosmetic dermatology · 2022
Randomized trial25 participantsflagAnti-Aging forscienceVitamin C
- Clinical Applications of Vitamin C in Dermatology: A Systematic Review.
Boghosian T; Mendez H; Boghosian N; Sayegh M; Beer J; Tosti A · The Journal of clinical and aesthetic dermatology · 2026
Systematic review44 studies pooledflagAnti-Aging forscienceVitamin C
- Low-Molecular-Weight Collagen Peptide Supplementation Improves Cellulite Severity, Skin Elasticity, and Hair Shaft Diameter: A Clinical Study with Pharmacokinetic Evaluation.
Hwang S; Won J; Kim S; Kang W; Park M · Journal of medicinal food · 2026
Randomized trial114 participantsflagHair Health forscienceCollagen
- Calcium and Vitamin D Supplementation with and Without Collagen on Bone Density and Skin Elasticity in Menopausal Women-A Randomized Controlled Study.
Duangjai A; Srivilai J; Nangola S; Amornlerdpison D · Clinics and practice · 2025
Randomized trialflagHair Health forscienceCollagen
- Dietary Collagen Supplementation as a Strategy for Skin Health: A Narrative Review of Clinical Effects on Skin, Hair, Nails, and Wound Healing.
Biełach-Bazyluk A; Jurga M; Flisiak I; Zbroch E · Nutrients · 2026
Narrative reviewflagHair Health forscienceCollagen
- Management of hair loss associated with endocrine therapy in patients with breast cancer: an overview.
Karatas F; Sahin S; Sever AR; Altundag K · SpringerPlus · 2016
Narrative reviewflagHair Health forscienceVitamin C
- Elucidating causal relationships of diet-derived circulating antioxidants and the risk of non-scarring alopecia: A Mendelian randomization study.
Ba Y; Shen L; Peng X; Zhang Y; Wang J · Medicine · 2024
Methods validation study201,019 participantsflagHair Health forscienceVitamin C
- Alterations of plasma antioxidants and mitochondrial DNA mutation in hair follicles of smokers.
Liu CS; Chen HW; Lii CK; Tsai CS; Kuo CL; Wei YH · Environmental and molecular mutagenesis · 2002
Observational studyflagHair Health forscienceVitamin C
- Removal of synthetic hair dye using formamidine sulfinic acid and other sulfinate precursors.
Hawkes JA; Lewis DM; Mama J; Murray J · International journal of cosmetic science · 2026
Methods validation studyflagHair Health forscienceVitamin C
- A Zinc Sulphate-Resistant Acrodermatitis Enteropathica Patient with a Novel Mutation in SLC39A4 Gene.
Kilic M; Taskesen M; Coskun T; Gürakan F; Tokatli A; Sivri HS; Dursun A; Schmitt S; Küry S · JIMD reports · 2013
Case reportflagHair Health forscienceVitamin C
- Oral supplementation with specific bioactive collagen peptides improves nail growth and reduces symptoms of brittle nails.
Hexsel D; Zague V; Schunck M; Siega C; Camozzato FO; Oesser S · Journal of cosmetic dermatology · 2018
Single-arm trial25 participantsflagNail Health forscienceCollagen
- Influence of collagen peptide supplementation on visible signs of skin and nail health and -aging in an East Asian population: A double blind, randomized, placebo-controlled trial.
Vleminckx S; Virgilio N; Asserin J; Prawitt J; Silva CIF · Journal of cosmetic dermatology · 2024
Randomized trial85 participantsflagNail Health forscienceCollagen
- Nail Supplements: When, How, and Why?
Zaraa I; Richert B · Skin appendage disorders · 2026
Narrative reviewflagNail Health forscienceCollagen
- Expanding the COL7A1 mutation database: novel and recurrent mutations and unusual genotype-phenotype constellations in 41 patients with dystrophic epidermolysis bullosa.
Kern JS; Kohlhase J; Bruckner-Tuderman L; Has C · The Journal of investigative dermatology · 2006
Observational study41 participantsflagNail Health forscienceCollagen
- Vitamin C Deficiency in Inflammatory Bowel Disease: The Forgotten Micronutrient.
Dunleavy KA; Ungaro RC; Manning L; Gold S; Novak J; Colombel JF · Crohn's & colitis 360 · 2023
Other20 participantsflagNail Health forscienceVitamin C
- Evaluation of the anti-wrinkle effect of an ascorbic acid-loaded dissolving microneedle patch via a double-blind, placebo-controlled clinical study.
Lee C; Yang H; Kim S; Kim M; Kang H; Kim N; An S; Koh J; Jung H · International journal of cosmetic science · 2017
Randomized trial23 participantsflagSkin Health forscienceVitamin C
- Comparative Study on the Outcome of Periorbital Wrinkles Treated with Laser-Assisted Delivery of Vitamin C or Vitamin C Plus Growth Factors: A Randomized, Double-blind, Clinical Trial.
Machado BHB; Frame J; Zhang J; Najlah M · Aesthetic plastic surgery · 2021
Randomized trial149 participantsflagSkin Health forscienceVitamin C
- Randomized trial of topical ascorbic acid in DMSO versus imiquimod for the treatment of basal cell carcinoma.
Burke B; Bailie JE · Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie · 2022
Randomized trial25 participantsflagSkin Health forscienceVitamin C
- Vitamin C improves healing of foot ulcers: a randomised, double-blind, placebo-controlled trial.
Gunton JE; Girgis CM; Lau T; Vicaretti M; Begg L; Flood V · The British journal of nutrition · 2022
Randomized trial16 participantsflagSkin Health forscienceVitamin C
- Dietary nutrient intakes and skin-aging appearance among middle-aged American women.
Cosgrove MC; Franco OH; Granger SP; Murray PG; Mayes AE · The American journal of clinical nutrition · 2007
Cross-sectional study4,025 participantsflagSkin Health forscienceVitamin C