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Collagen 6000 mg

youtheory
4.6
★ ★ ★ ★ ★
(94961 ratings)
Collagen 6000 mg
Product Image
Score85
A substantial 6 g hydrolyzed collagen serving with vitamin C and strong value, balanced by a high tablet count and limited quality disclosure.
How scoring works
Quantity:290 Tablet(s) • (48 servings)
Goals:
Skin Health
Nail Health
Joint Health
Hair Health
Anti-Aging
Bone Health
Anti-Inflammatory Support
General Health

Score 85

A substantial 6 g hydrolyzed collagen serving with vitamin C and strong value, balanced by a high tablet count and limited quality disclosure.
How scoring works
$18.39($0.38 per serving)
iHerb
$ 19.99
Pure Formulas
$ 18.39
Vitacost
$ 21.93
Amazon
$ 19.99
Walmart
$ 19.99
Report prices

Analysis

Hydrolyzed collagen provides 6 g per serving, a useful midrange amount for structural support. Vitamin C adds a clearly disclosed companion nutrient, although the serving requires several tablets.

Animal source, collagen types, matching protein, and amino acid details are missing. The large tablet supply supports consistent use but may be cumbersome compared with powder.

Cost efficiency is strong for the collagen amount delivered. It works for users who want a substantial tablet serving and place quantity above sourcing detail.

Who is it for
  • People seeking a substantial tablet serving
  • Value-focused collagen users
Best for
  • Regular multi-gram intake
  • Users who do not want powder

Pros

  • 6 g of hydrolyzed collagen
  • Includes vitamin C
  • Strong collagen-specific value

Cons

  • Several tablets per serving
  • Animal source and collagen types are missing
  • No protein or amino acid verification

Nutrient quality

93 Highest impact

Hydrolyzed collagen supports digestion, and calcium ascorbate is a buffered vitamin C form. The 6,000 mg collagen amount is substantial, while 90 mg of vitamin C provides a useful cofactor.

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Ingredient transparency

77 High impact

Both active ingredients have clearly stated amounts. Serving count is supplied, but complete directions and inactive ingredients are not shown.

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Customer satisfaction

71 High impact

The supplied aggregate average is favorable and comes from a very large response pool. No specific firsthand feedback is provided to assess recurring complaints or whether experience matches the intended use.

.

Value for money

97 Highest impact

A substantial collagen amount is delivered at very low cost. The simple formula compares favorably despite its large tablet serving.

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Report analysis

Goals

Skin Health
Impact
Highest effect
A Goal FitA Strength of SupportB+ CoverageA+ Formula Quality
Vitamin C · 90 mgCollagen · 6000 mg

Hydrolyzed collagen at a useful amount provides strong structural support for skin. Vitamin C complements the body's collagen-building process.

The animal source, collagen types, and amino acid profile are not disclosed, limiting quality verification. Even so, the focused formula supplies meaningful amounts without unrelated ingredients.

Study evidence
Collagen Supportive 62 studies
Vitamin C Supportive 53 studies
Nail Health
Impact
Highest effect
A- Goal FitA- Strength of SupportB- CoverageA+ Formula Quality
Collagen · 6000 mg

Hydrolyzed collagen supplies a substantial structural-protein amount, and vitamin C supports collagen formation. The combination is directly relevant to nail plate strength but does not add biotin, zinc, or silicon.

The 6 g collagen amount is clearly disclosed and hydrolysis supports digestion. Missing animal source, collagen types, protein match, and amino acid details limit quality verification.

Study evidence
Collagen Supportive 4 studies
Vitamin C Supportive 1 study
Joint Health
Impact
Highest effect
A Goal FitA- Strength of SupportB- CoverageA+ Formula Quality
Collagen · 6000 mg

Hydrolyzed collagen provides a useful structural dose for cartilage and connective tissue. Vitamin C supports collagen synthesis and complements the peptide supply.

Reaching the full serving requires six tablets, which may be inconvenient. The animal source, collagen types, and amino acid profile are not disclosed.

Study evidence
Collagen Supportive 49 studies
Vitamin C Disputed 24 studies
Hair Health
Impact
Highest effect
B- Goal FitA Strength of SupportC+ CoverageA+ Formula Quality
Vitamin C · 90 mgCollagen · 6000 mg

Hydrolyzed collagen supplies amino acids that may support hair fiber and the scalp dermis. Evidence for direct hair growth is less established than evidence for skin structure.

A substantial hydrolyzed collagen amount provides the main structural contribution. Vitamin C is a logical cofactor, though the large tablet serving may be inconvenient.

Study evidence
Collagen Supportive 3 studies
Vitamin C Mixed 5 studies
Anti-Aging
Impact
High effect
B Goal FitB Strength of SupportC+ CoverageA+ Formula Quality
Collagen · 6000 mg

Six grams of hydrolyzed collagen offers direct structural support for skin and connective tissue. Human evidence is most relevant to skin, connective tissue, and joint function rather than cellular aging.

The collagen amount is useful and vitamin C provides a relevant synthesis cofactor. Source, collagen types, and amino acid composition are not supplied.

Study evidence
Collagen Supportive 33 studies
Vitamin C Supportive 30 studies
Bone Health
Impact
High effect
B Goal FitB Strength of SupportC- CoverageA- Formula Quality
Vitamin C · 90 mgCollagen · 6000 mg

Six grams of hydrolyzed collagen supplies meaningful protein-matrix material for bone resilience. Vitamin C supports normal collagen formation and complements the peptide ingredient.

The label omits animal source, collagen types, branded sourcing, and an amino acid profile. Calcium, magnesium, vitamin D, and vitamin K are absent, leaving mineralization and calcium regulation outside the formula.

Study evidence
Collagen Supportive 16 studies
Vitamin C Supportive 46 studies

Ingredients

IngredientAmount per serving
Vitamin C (Calcium Ascorbate)
90 mg
Collagen, Hydrolyzed
6000 mg
Gluten Free Adults 18–50 Dairy Free Women
Report overview
Collagen · 6000 mg OverallScore59
D+ Active Ingredient Quality & BioavailabilityD Dose, Safety & Label TransparencyA+ Value

Hydrolyzed collagen at six grams combines an absorbable form with a useful midrange amount. Source, type, protein-match, and amino acid details are missing, so the label offers limited quality verification. The amount delivered at each serving makes the cost per gram highly efficient.

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Sources

Published studies used for the product analysis and the top-ranked studies for each ingredient and goal.

  1. Oral intake of collagen peptide NS improves hydration, elasticity, desquamation, and wrinkling in human skin: a randomized, double-blinded, placebo-controlled study.
    Lee M; Kim E; Ahn H; Son S; Lee H · Food & function · 2023
    Randomized trial100 participantsAnti-Aging Skin Health forCollagen
  2. Effects of hydrolyzed collagen supplementation on skin aging: a systematic review and meta-analysis.
    de Miranda RB; Weimer P; Rossi RC · International journal of dermatology · 2021
    Meta-analysis1,125 participants19 studies pooledAnti-Aging Skin Health forCollagen
  3. Oral supplementation of specific collagen peptides has beneficial effects on human skin physiology: a double-blind, placebo-controlled study.
    Proksch E; Segger D; Degwert J; Schunck M; Zague V; Oesser S · Skin pharmacology and physiology · 2014
    Randomized trial69 participantsAnti-Aging forCollagen
  4. Skin Anti-Aging and Moisturizing Effects of Low-Molecular-Weight Collagen Peptide Supplementation in Healthy Adults: A Randomized, Double-Blind, Placebo-Controlled Clinical Trial.
    Lee E; Ahn DK; Kim JH; Lee S; Kim HJ; Lee HK; Shin JH · Journal of microbiology and biotechnology · 2025
    Randomized trial70 participantsAnti-Aging forCollagen
  5. Oral intake of specific bioactive collagen peptides reduces skin wrinkles and increases dermal matrix synthesis.
    Proksch E; Schunck M; Zague V; Segger D; Degwert J; Oesser S · Skin pharmacology and physiology · 2014
    Randomized trial114 participantsAnti-Aging forCollagen
  6. Study on the Multiple Efficacies of Vitamin C Serum in Anti-Glycation, Anti-Carbonylation, Antioxidation, and Anti-Inflammation of Human Skin Based on In Vivo Tests.
    Zi Y; Liu J; Liu Q; Pan Y; Jiang X · Journal of cosmetic dermatology · 2026
    Randomized trial66 participantsAnti-Aging forVitamin C
  7. Evaluation of the anti-wrinkle effect of a lipophilic pro-vitamin C derivative, tetra-isopalmitoyl ascorbic acid.
    Yokota M; Yahagi S · Journal of cosmetic dermatology · 2022
    Randomized trial69 participantsAnti-Aging forVitamin C
  8. The role of vitamin C in pushing back the boundaries of skin aging: an ultrasonographic approach.
    Crisan D; Roman I; Crisan M; Scharffetter-Kochanek K; Badea R · Clinical, cosmetic and investigational dermatology · 2015
    Clinical trial60 participantsAnti-Aging forVitamin C
  9. In vivo evaluation of topical ascorbic acid application on skin aging by 50 MHz ultrasound.
    Vergilio MM; Aiello LM; Furlan AS; Caritá AC; Azevedo JR; Bolzinger MA; Chevalier Y; Leonardi GR · Journal of cosmetic dermatology · 2022
    Randomized trial25 participantsAnti-Aging forVitamin C
  10. Clinical Applications of Vitamin C in Dermatology: A Systematic Review.
    Boghosian T; Mendez H; Boghosian N; Sayegh M; Beer J; Tosti A · The Journal of clinical and aesthetic dermatology · 2026
    Systematic review44 studies pooledAnti-Aging forVitamin C
  11. Undenatured type II collagen for knee osteoarthritis.
    Gupta A; Maffulli N · Annals of medicine · 2025
    Systematic review12 studies pooledAnti-Inflammatory Support forCollagen
  12. Anti-inflammatory effect of collagen tripeptide in atopic dermatitis.
    Hakuta A; Yamaguchi Y; Okawa T; Yamamoto S; Sakai Y; Aihara M · Journal of dermatological science · 2018
    Randomized trial17 participantsAnti-Inflammatory Support forCollagen
  13. [Points of undenatured type II collagen application in musculoskeletal pain syndromes treatment].
    Shavlovskaya OA; Gromova OA; Torshin IY · Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova · 2022
    Narrative reviewAnti-Inflammatory Support forCollagen
  14. Ultrasound Guided Injection of Collagen for Elbow Lateral Epicondylitis - A Pilot Study.
    Porta F; Filippucci E; Barni X; Dinescu SC; Vreju FA · Current health sciences journal · 2026
    Single-arm trial13 participantsAnti-Inflammatory Support forCollagen
  15. Effects of porcine-derived collagen hydrolysates on 24 h blood pressure profiles, markers for endothelial dysfunction and low-grade inflammation and the retinal vasculature in adults with overweight/obesity: a randomized, controlled trial.
    Chavez-Alfaro MA; Mensink RP; Joris PJ; Plat J · Food & function · 2025
    Randomized trial56 participantsAnti-Inflammatory Support forCollagen
  16. Efficacy of Vitamin C as Glucocorticoid Substitute for Reducing Pain and Inflammation After Total Hip Arthroplasty: A Randomized Controlled Trial.
    Jiang W; Xu H; Jiang X; Zhan Y; Ju Y; Xie J; Huang Z; Huang Q; Pei F · The Journal of bone and joint surgery. American volume · 2025
    Randomized trial107 participantsAnti-Inflammatory Support Joint Health forVitamin C
  17. The Impact of Vitamin C on Analgesic, Anti-inflammatory, and Hemostatic Outcomes After Total Hip and Knee Arthroplasty: A Systematic Review and Meta-Analysis.
    Moftakhari Hajimirzaei S; Bagherzadeh Cham M; Dolikhani M; Tabatabaee SM; Ebrahimpour A · The archives of bone and joint surgery · 2026
    Meta-analysis1,162 participants10 studies pooledAnti-Inflammatory Support forVitamin C
  18. The impact of vitamin C supplementation on the perioperative outcomes after total hip and knee arthroplasty: a systematic review and meta-analysis.
    Liu X; Guo J; Li Y; Yang Y; Liu M; Gao Q; Yang Y; Wu X; Yue C · BMC musculoskeletal disorders · 2026
    Meta-analysis852 participants8 studies pooledAnti-Inflammatory Support forVitamin C
  19. Therapeutic Impact of Ascorbic Acid on Oral and Periodontal Tissues: A Systematic Literature Review.
    Ruzijevaite G; Acaite E; Jagelaviciene E · Medicina (Kaunas, Lithuania) · 2025
    Systematic review811 participants17 studies pooledAnti-Inflammatory Support forVitamin C
  20. Oral vitamin C administration reduces early recurrence rates after electrical cardioversion of persistent atrial fibrillation and attenuates associated inflammation.
    Korantzopoulos P; Kolettis TM; Kountouris E; Dimitroula V; Karanikis P; Pappa E; Siogas K; Goudevenos JA · International journal of cardiology · 2005
    Randomized trial44 participantsAnti-Inflammatory Support forVitamin C
  21. Effect of Calcium and Vitamin D Supplementation With and Without Collagen Peptides on Volumetric and Areal Bone Mineral Density, Bone Geometry and Bone Turnover in Postmenopausal Women With Osteopenia.
    Lampropoulou-Adamidou K; Karlafti E; Argyrou C; Makris K; Trovas G; Dontas IA; Tournis S; Triantafyllopoulos IK · Journal of clinical densitometry : the official journal of the International Society for Clinical Densitometry · 2022
    Randomized trial51 participantsBone Health forCollagen
  22. Bone turnover and bone collagen maturation in osteoporosis: effects of antiresorptive therapies.
    Byrjalsen I; Leeming DJ; Qvist P; Christiansen C; Karsdal MA · Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2008
    Randomized trialBone Health forCollagen
  23. A calcium-collagen chelate dietary supplement attenuates bone loss in postmenopausal women with osteopenia: a randomized controlled trial.
    Elam ML; Johnson SA; Hooshmand S; Feresin RG; Payton ME; Gu J; Arjmandi BH · Journal of medicinal food · 2015
    Randomized trial39 participantsBone Health forCollagen
  24. Assessment of Osteoporosis in Lumbar Spine: In Vivo Quantitative MR Imaging of Collagen Bound Water in Trabecular Bone.
    Liu J; Liao JW; Li W; Chen XJ; Feng JX; Yao L; Huang PH; Su ZH; Lu H; Liao YT; Li SL; Ma YJ · Frontiers in endocrinology · 2022
    Methods validation study189 participantsBone Health forCollagen
  25. Effect of calcium and vitamin D supplementation with and without collagen peptides on bone turnover in postmenopausal women with osteopenia.
    Argyrou C; Karlafti E; Lampropoulou-Adamidou K; Tournis S; Makris K; Trovas G; Dontas I; Triantafyllopoulos IK · Journal of musculoskeletal & neuronal interactions · 2021
    Randomized trial51 participantsBone Health forCollagen
  26. Can Dietary Intake of Vitamin C-Oriented Foods Reduce the Risk of Osteoporosis, Fracture, and BMD Loss? Systematic Review With Meta-Analyses of Recent Studies.
    Zeng LF; Luo MH; Liang GH; Yang WY; Xiao X; Wei X; Yu J; Guo D; Chen HY; Pan JK; Huang HT; Liu Q; Guan ZT; Han YH; Zhao D; Zhao JL; Hou SR; Wu M; Lin JT; Li JH; Liang WX; Ou AH; Wang Q; Li ZP; Liu J · Frontiers in endocrinology · 2020
    Meta-analysis19,484 participants17 studies pooledBone Health forVitamin C
  27. Dietary vitamin C intake and the risk of hip fracture: a dose-response meta-analysis.
    Sun Y; Liu C; Bo Y; You J; Zhu Y; Duan D; Cui H; Lu Q · Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2019
    Meta-analysis6 studies pooledBone Health forVitamin C
  28. Smoking, antioxidant vitamins, and the risk of hip fracture.
    Melhus H; Michaëlsson K; Holmberg L; Wolk A; Ljunghall S · Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research · 1999
    Cohort study66,651 participantsBone Health forVitamin C
  29. Micronutrients and the risk of hip fracture: Case-control study.
    Torbergsen AC; Watne LO; Wyller TB; Frihagen F; Strømsøe K; Bøhmer T; Mowe M · Clinical nutrition (Edinburgh, Scotland) · 2018
    Case-control study189 participantsBone Health forVitamin C
  30. Favorable effect of dietary vitamin C on bone mineral density in postmenopausal women (KNHANES IV, 2009): discrepancies regarding skeletal sites, age, and vitamin D status.
    Kim YA; Kim KM; Lim S; Choi SH; Moon JH; Kim JH; Kim SW; Jang HC; Shin CS · Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2016
    Cross-sectional study1,196 participantsBone Health forVitamin C
  31. A double-blind, placebo-controlled, randomised, clinical study on the effectiveness of collagen peptide on osteoarthritis.
    Kumar S; Sugihara F; Suzuki K; Inoue N; Venkateswarathirukumara S · Journal of the science of food and agriculture · 2015
    Randomized trialGeneral Health forCollagen
  32. Efficacy and safety of native type II collagen in modulating knee osteoarthritis symptoms: a randomised, double-blind, placebo-controlled trial.
    Luo C; Su W; Song Y; Srivastava S · Journal of experimental orthopaedics · 2023
    Randomized trial101 participantsGeneral Health Joint Health forCollagen
  33. Healing Process, Pain, and Health-Related Quality of Life in Patients with Venous Leg Ulcers Treated with Fish Collagen Gel: A 12-Week Randomized Single-Center Study.
    Mościcka P; Cwajda-Białasik J; Szewczyk MT; Jawień A · International journal of environmental research and public health · 2022
    Randomized trial100 participantsGeneral Health forCollagen
  34. Efficacy and Safety of Dietary Undenatured Type II Collagen on Joint and Motor Function in Healthy Volunteers: A Randomized, Double-Blind, Placebo-Controlled, Parallel-Group Study.
    Shiojima Y; Takahashi M; Takahashi R; Maruyama K; Moriyama H; Bagchi D; Bagchi M; Akanuma M · Journal of the American Nutrition Association · 2023
    Randomized trial64 participantsGeneral Health forCollagen
  35. The use of a collagen matrix in hard-to-heal venous leg ulcers.
    Romanelli M; Mulder G; Paggi B; Macchia M; Panduri S; Dini V · Journal of wound care · 2016
    Randomized trial40 participantsGeneral Health forCollagen
  36. Dietary intake and blood concentrations of antioxidants and the risk of cardiovascular disease, total cancer, and all-cause mortality: a systematic review and dose-response meta-analysis of prospective studies.
    Aune D; Keum N; Giovannucci E; Fadnes LT; Boffetta P; Greenwood DC; Tonstad S; Vatten LJ; Riboli E; Norat T · The American journal of clinical nutrition · 2019
    Meta-analysis69 studies pooledGeneral Health forVitamin C
  37. Scientific Opinion on the substantiation of a health claim related to vitamin C and increasing non haem iron absorption pursuant to Article 14 of Regulation (EC) No 1924/2006.
    EFSA Panel on Dietetic Products, Nutrition and Allergies (NDA) · EFSA journal. European Food Safety Authority · 2026
    Guideline / consensusGeneral Health forVitamin C
  38. Vitamin C Depletion and All-Cause Mortality in Renal Transplant Recipients.
    Sotomayor CG; Eisenga MF; Gomes Neto AW; Ozyilmaz A; Gans ROB; Jong WHA; Zelle DM; Berger SP; Gaillard CAJM; Navis GJ; Bakker SJ · Nutrients · 2018
    Cohort study598 participantsGeneral Health forVitamin C
  39. Associations of Serum Biomarkers of Fruit and Vegetable Intake With the Risk of Cause-Specific Mortality and All-Cause Mortality: A National Prospective Cohort Study.
    Pu L; Zhang R; Wang X; Zhao T; Sun H; Han L · Frontiers in nutrition · 2022
    Cohort study12,530 participantsGeneral Health forVitamin C
  40. Relation between plasma ascorbic acid and mortality in men and women in EPIC-Norfolk prospective study: a prospective population study. European Prospective Investigation into Cancer and Nutrition.
    Khaw KT; Bingham S; Welch A; Luben R; Wareham N; Oakes S; Day N · Lancet (London, England) · 2001
    Cohort study19,496 participantsGeneral Health forVitamin C
  41. Low-Molecular-Weight Collagen Peptide Supplementation Improves Cellulite Severity, Skin Elasticity, and Hair Shaft Diameter: A Clinical Study with Pharmacokinetic Evaluation.
    Hwang S; Won J; Kim S; Kang W; Park M · Journal of medicinal food · 2026
    Randomized trial114 participantsHair Health forCollagen
  42. Calcium and Vitamin D Supplementation with and Without Collagen on Bone Density and Skin Elasticity in Menopausal Women-A Randomized Controlled Study.
    Duangjai A; Srivilai J; Nangola S; Amornlerdpison D · Clinics and practice · 2025
    Randomized trialHair Health forCollagen
  43. Dietary Collagen Supplementation as a Strategy for Skin Health: A Narrative Review of Clinical Effects on Skin, Hair, Nails, and Wound Healing.
    Biełach-Bazyluk A; Jurga M; Flisiak I; Zbroch E · Nutrients · 2026
    Narrative reviewHair Health forCollagen
  44. Management of hair loss associated with endocrine therapy in patients with breast cancer: an overview.
    Karatas F; Sahin S; Sever AR; Altundag K · SpringerPlus · 2016
    Narrative reviewHair Health forVitamin C
  45. Elucidating causal relationships of diet-derived circulating antioxidants and the risk of non-scarring alopecia: A Mendelian randomization study.
    Ba Y; Shen L; Peng X; Zhang Y; Wang J · Medicine · 2024
    Methods validation study201,019 participantsHair Health forVitamin C
  46. Alterations of plasma antioxidants and mitochondrial DNA mutation in hair follicles of smokers.
    Liu CS; Chen HW; Lii CK; Tsai CS; Kuo CL; Wei YH · Environmental and molecular mutagenesis · 2002
    Observational studyHair Health forVitamin C
  47. Removal of synthetic hair dye using formamidine sulfinic acid and other sulfinate precursors.
    Hawkes JA; Lewis DM; Mama J; Murray J · International journal of cosmetic science · 2026
    Methods validation studyHair Health forVitamin C
  48. A Zinc Sulphate-Resistant Acrodermatitis Enteropathica Patient with a Novel Mutation in SLC39A4 Gene.
    Kilic M; Taskesen M; Coskun T; Gürakan F; Tokatli A; Sivri HS; Dursun A; Schmitt S; Küry S · JIMD reports · 2013
    Case reportHair Health forVitamin C
  49. Management and Amelioration of Knee Joint Osteoarthritis in Adults Using a Novel High-Functional Bovine Collagen Peptide as a Nutritional Therapy: A Double-Blind, Prospective, Multicentric, Randomized, Active and Placebo Controlled, Five-Arm, Clinical Study to Evaluate the Efficacy, Safety, and Tolerability.
    Devasia S; Joseph JT; P S S; Koizumi S; Clarke L; V T S; Kailas AP; Madhavan S · Cartilage · 2024
    Randomized trial100 participantsJoint Health forCollagen
  50. Efficacy and tolerability of an undenatured type II collagen supplement in modulating knee osteoarthritis symptoms: a multicenter randomized, double-blind, placebo-controlled study.
    Lugo JP; Saiyed ZM; Lane NE · Nutrition journal · 2016
    Randomized trial191 participantsJoint Health forCollagen
  51. [Efficacy and safety of undenatured type II collagen in patients with knee osteoarthritis: a multicenter, prospective, double-blind, placebo-controlled, randomized trial].
    Alekseeva LI; Kashevarova NG; Taskina EA; Strebkova EA; Korotkova TA; Sharapova EP; Savushkina NM; Lila AM; Shostak NA; Mazurov VI; Nesterovich II; Dedkova VA; Vasilyuk VB; Egorova NV; Leontyeva MA; Yakupova SP; Vinogradova IB; Sorotskaya VN; Shirokova LY · Terapevticheskii arkhiv · 2024
    Randomized trial212 participantsJoint Health forCollagen
  52. The Influence of Specific Bioactive Collagen Peptides on Knee Joint Discomfort in Young Physically Active Adults: A Randomized Controlled Trial.
    Zdzieblik D; Brame J; Oesser S; Gollhofer A; König D · Nutrients · 2021
    Randomized trial180 participantsJoint Health forCollagen
  53. Effects of Multiple Intravenous Doses of Perioperative Vitamin C on Pain Management Following Total Hip Arthroplasty.
    Han G; Ye Y; Kang P · Drug design, development and therapy · 2025
    Randomized trial100 participantsJoint Health forVitamin C
  54. Osteoarthritis prevalence and modifiable factors: a population study.
    Plotnikoff R; Karunamuni N; Lytvyak E; Penfold C; Schopflocher D; Imayama I; Johnson ST; Raine K · BMC public health · 2016
    Cross-sectional study4,733 participantsJoint Health forVitamin C
  55. Anti-Inflammatory Effect of Vitamin C during the Postoperative Period in Patients Subjected to Total Knee Arthroplasty: A Randomized Controlled Trial.
    Ramón R; Holguín E; Chiriboga JD; Rubio N; Ballesteros C; Ezechieli M · Journal of personalized medicine · 2023
    Randomized trial110 participantsJoint Health forVitamin C
  56. Musculoskeletal manifestations of scurvy.
    Fain O · Joint bone spine · 2005
    Narrative reviewJoint Health forVitamin C
  57. Oral supplementation with specific bioactive collagen peptides improves nail growth and reduces symptoms of brittle nails.
    Hexsel D; Zague V; Schunck M; Siega C; Camozzato FO; Oesser S · Journal of cosmetic dermatology · 2018
    Single-arm trial25 participantsNail Health forCollagen
  58. Influence of collagen peptide supplementation on visible signs of skin and nail health and -aging in an East Asian population: A double blind, randomized, placebo-controlled trial.
    Vleminckx S; Virgilio N; Asserin J; Prawitt J; Silva CIF · Journal of cosmetic dermatology · 2024
    Randomized trial85 participantsNail Health forCollagen
  59. Nail Supplements: When, How, and Why?
    Zaraa I; Richert B · Skin appendage disorders · 2026
    Narrative reviewNail Health forCollagen
  60. Expanding the COL7A1 mutation database: novel and recurrent mutations and unusual genotype-phenotype constellations in 41 patients with dystrophic epidermolysis bullosa.
    Kern JS; Kohlhase J; Bruckner-Tuderman L; Has C · The Journal of investigative dermatology · 2006
    Observational study41 participantsNail Health forCollagen
  61. Vitamin C Deficiency in Inflammatory Bowel Disease: The Forgotten Micronutrient.
    Dunleavy KA; Ungaro RC; Manning L; Gold S; Novak J; Colombel JF · Crohn's & colitis 360 · 2023
    Other20 participantsNail Health forVitamin C
  62. Exploring the Impact of Hydrolyzed Collagen Oral Supplementation on Skin Rejuvenation: A Systematic Review and Meta-Analysis.
    Dewi DAR; Arimuko A; Norawati L; Yenny SW; Setiasih NL; Perdiyana A; Arkania N; Nadhira F; Wiliantari N · Cureus · 2024
    Meta-analysis967 participants14 studies pooledSkin Health forCollagen
  63. Effects of collagen-based supplements on skin's hydration and elasticity: A systematic review and meta-analysis.
    Danessa G; Notario D; Regina R · Indian journal of dermatology, venereology and leprology · 2025
    Meta-analysis646 participants10 studies pooledSkin Health forCollagen
  64. Oral Intake of Low-Molecular-Weight Collagen Peptide Improves Hydration, Elasticity, and Wrinkling in Human Skin: A Randomized, Double-Blind, Placebo-Controlled Study.
    Kim DU; Chung HC; Choi J; Sakai Y; Lee BY · Nutrients · 2018
    Randomized trial64 participantsSkin Health forCollagen
  65. Evaluation of the anti-wrinkle effect of an ascorbic acid-loaded dissolving microneedle patch via a double-blind, placebo-controlled clinical study.
    Lee C; Yang H; Kim S; Kim M; Kang H; Kim N; An S; Koh J; Jung H · International journal of cosmetic science · 2017
    Randomized trial23 participantsSkin Health forVitamin C
  66. Comparative Study on the Outcome of Periorbital Wrinkles Treated with Laser-Assisted Delivery of Vitamin C or Vitamin C Plus Growth Factors: A Randomized, Double-blind, Clinical Trial.
    Machado BHB; Frame J; Zhang J; Najlah M · Aesthetic plastic surgery · 2021
    Randomized trial149 participantsSkin Health forVitamin C
  67. Randomized trial of topical ascorbic acid in DMSO versus imiquimod for the treatment of basal cell carcinoma.
    Burke B; Bailie JE · Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie · 2022
    Randomized trial25 participantsSkin Health forVitamin C
  68. Vitamin C improves healing of foot ulcers: a randomised, double-blind, placebo-controlled trial.
    Gunton JE; Girgis CM; Lau T; Vicaretti M; Begg L; Flood V · The British journal of nutrition · 2022
    Randomized trial16 participantsSkin Health forVitamin C
  69. Dietary nutrient intakes and skin-aging appearance among middle-aged American women.
    Cosgrove MC; Franco OH; Granger SP; Murray PG; Mayes AE · The American journal of clinical nutrition · 2007
    Cross-sectional study4,025 participantsSkin Health forVitamin C