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Melatonin Lozenge 2.5 mg

Nature's Way
4.7
★ ★ ★ ★ ★
(1079 ratings)
Melatonin 2.5 mg
Product Image
Score86
2.5 mg of melatonin is a strong single-ingredient option with strong value. Its main trade-off is the low dose, which may be either convenient or restrictive depending on the intended routine.
How scoring works
Quantity:100 Liquid(s) • (100 servings)
Goals:
Sleep Support

Score 86

2.5 mg of melatonin is a strong single-ingredient option with strong value. Its main trade-off is the low dose, which may be either convenient or restrictive depending on the intended routine.
How scoring works
$6.61($0.06 per serving)
iHerb
$ 7.59
Vitacost
$ 7.59
Vitacost
$ 7.59
iHerb
$ 7.59
Pure Formulas
$ 6.61
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Analysis

The 2.5 mg serving provides melatonin in liquid(s), giving a clear and focused option. The amount is best suited to people looking for a low intake rather than a broad multi-ingredient formula.

The amount is stated, but the supplied information leaves some formulation detail unspecified. Value is favorable for the supplied amount and serving count, and the simple formula makes comparison with other CoQ10 products easier.

The strongest practical fit is sleep support, with related assessments also supporting sleep-timing routines. The main decision is whether 2.5 mg and the liquid(s) format match the user's preferred routine and budget.

Who is it for
  • Adults seeking a low-dose Melatonin supplement
  • People who prefer liquid(s) for melatonin
  • Users focused on sleep support
Best for
  • Sleep Support support

Pros

  • Clearly stated 2.5 mg amount
  • Focused melatonin formula
  • Serving amount is easy to identify
  • Favorable value for the supplied quantity

Cons

  • 2.5 mg may require multiple servings for higher-intake routines
  • Liquid(s) may not suit every user's format preference
  • Single-active formula provides no complementary nutrients

Warnings

  • Melatonin can cause next-day drowsiness; avoid driving or other alertness-dependent tasks if that effect occurs.
  • Combining melatonin with alcohol or other sedating products can increase drowsiness.

Nutrient quality

94 Highest impact

Lozenge delivery supports prompt sleep initiation but does not provide sustained release. The melatonin amount is well aligned with common sleep-onset use.

Ingredient transparency

81 Highest impact

The melatonin amount and any listed active companions are specifically disclosed. A basic carbohydrate amount is disclosed, but the complete lozenge excipients are not provided.

Customer satisfaction

72 High impact

The supplied average rating is strong. The large rating sample provides strong statistical confidence.

Value for money

97 Highest impact

Appropriate dosing and prompt delivery provide strong quality. The very low serving cost provides excellent value.

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Goals

Sleep Support
Impact
Highest effect
A+ Goal FitA+ Strength of SupportC- CoverageA+ Formula Quality
Melatonin · 2.5 mg

The 2.5 mg melatonin amount directly supports sleep onset and circadian timing within a practical range. The lozenge can dissolve quickly and is well suited to sleep onset.

No sustained-release system is stated for overnight maintenance. The focused formula does not address muscle relaxation or other barriers to staying asleep.

Study evidence
Melatonin Supportive 181 studies

Ingredients

IngredientAmount per serving
Total Carbohydrates
0 Gram(s)
Melatonin
2.5 mg
Gluten Free Adults 18–50 Vegan Dairy Free Sugar Free Women Vegetarian
Report overview
Melatonin · 2.5 mg OverallScore76
F Active Ingredient Quality & BioavailabilityA+ Dose, Safety & Label TransparencyA+ Value

The 2.5 mg amount is well aligned with the preferred physiological range and comes in a clear one-lozenge serving. A lozenge can dissolve quickly for sleep initiation, but no sustained-release system is stated. The low serving cost supports good value, while independent purity certification is not documented.

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Sources

Published studies used for the product analysis and the top-ranked studies for each ingredient and goal.

  1. Meta-analysis: melatonin for the treatment of primary sleep disorders.
    Ferracioli-Oda E; Qawasmi A; Bloch MH · PloS one · 2013
    Meta-analysis1,683 participants19 studies pooledSleep Support forMelatonin
  2. Exogenous melatonin as a treatment for secondary sleep disorders: A systematic review and meta-analysis.
    Li T; Jiang S; Han M; Yang Z; Lv J; Deng C; Reiter RJ; Yang Y · Frontiers in neuroendocrinology · 2019
    Meta-analysis205 participants7 studies pooledSleep Support forMelatonin
  3. Efficacy of melatonin with behavioural sleep-wake scheduling for delayed sleep-wake phase disorder: A double-blind, randomised clinical trial.
    Sletten TL; Magee M; Murray JM; Gordon CJ; Lovato N; Kennaway DJ; Gwini SM; Bartlett DJ; Lockley SW; Lack LC; Grunstein RR; Rajaratnam SMW; Delayed Sleep on Melatonin (DelSoM) Study Group · PLoS medicine · 2019
    Randomized trial116 participantsSleep Support forMelatonin
  4. Melatonin treatment for age-related insomnia.
    Zhdanova IV; Wurtman RJ; Regan MM; Taylor JA; Shi JP; Leclair OU · The Journal of clinical endocrinology and metabolism · 2001
    Randomized trial30 participantsSleep Support forMelatonin
  5. Efficacy on sleep parameters and tolerability of melatonin in individuals with sleep or mental disorders: A systematic review and meta-analysis.
    Salanitro M; Wrigley T; Ghabra H; de Haan E; Hill CM; Solmi M; Cortese S · Neuroscience and biobehavioral reviews · 2022
    Meta-analysis1,998 participants34 studies pooledSleep Support forMelatonin
  6. Effects of Melatonin Treatment on Perioperative Sleep Quality: A Systematic Review and Meta-Analysis with Trial Sequential Analysis of Randomized Controlled Trials.
    Gao Y; Chen X; Zhou Q; Song J; Zhang X; Sun Y; Yu M; Li Y · Nature and science of sleep · 2022
    Meta-analysis725 participants10 studies pooledSleep Support forMelatonin
  7. Effects of melatonin on postoperative sleep quality: a systematic review, meta-analysis, and trial sequential analysis.
    Tsukinaga A; Mihara T; Takeshima T; Tomita M; Goto T · Canadian journal of anaesthesia = Journal canadien d'anesthesie · 2023
    Meta-analysis516 participants8 studies pooledSleep Support forMelatonin
  8. Unintended consequences: college students' melatonin usage, sleep disturbance, and depressive symptoms.
    Peltz JS; Rogge R · Sleep and biological rhythms · 2025
    Cohort study331 participantsSleep Support forMelatonin
  9. The Effectiveness of Melatonin for Sleep Disturbances in Parkinson' Disease: Systematic Review and Meta-Analysis.
    Yousef O; Abouelmagd ME; Khaddam H; Shbani A; Yousef R; Meshref M; Hanafi I · Journal of sleep research · 2026
    Meta-analysis409 participants8 studies pooledSleep Support forMelatonin
  10. Nightly treatment of primary insomnia with prolonged release melatonin for 6 months: a randomized placebo controlled trial on age and endogenous melatonin as predictors of efficacy and safety.
    Wade AG; Ford I; Crawford G; McConnachie A; Nir T; Laudon M; Zisapel N · BMC medicine · 2010
    Randomized trial791 participantsSleep Support forMelatonin
  11. Effects of exogenous melatonin on sleep: a meta-analysis.
    Brzezinski A; Vangel MG; Wurtman RJ; Norrie G; Zhdanova I; Ben-Shushan A; Ford I · Sleep medicine reviews · 2005
    Meta-analysis284 participants8 studies pooledSleep Support forMelatonin