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Detox Formula

Vital Nutrients
4.7
★ ★ ★ ★ ★
(79 ratings)
Glycine 250 mg
Taurine 250 mg
Glutamine 250 mg
Turmeric 100 mg
Milk Thistle 200 mg
Green Tea 25 mg
Product Image
Score58
A broad antioxidant and liver-support blend with sensible ingredients but mostly modest doses.
How scoring works
Quantity:60 Capsule(s) • (30 servings)
Goals:
Detoxification

Score 58

A broad antioxidant and liver-support blend with sensible ingredients but mostly modest doses.
How scoring works
$29.99($0.99 per serving)
iHerb
$ 29.99
Pure Formulas
$ 29.99
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Analysis

Glutamine, glycine, and taurine each provide 250 mg, while milk thistle contributes 200 mg. NAC, alpha-lipoic acid, turmeric, and several plant extracts broaden antioxidant support.

The formula covers many pathways but spreads the serving across numerous ingredients. Green tea catechins, grape seed, schisandra, broccoli, and other additions are present at relatively small amounts.

The blend suits people who prefer broad coverage over high doses of a few actives. It should be viewed as nutritional support, not a way to remove unspecified toxins.

Who is it for
  • Adults wanting a broad liver-support formula
  • People seeking amino acids plus botanicals
Best for
  • Milk thistle and NAC combinations
  • Broad antioxidant support

Pros

  • Provides glycine, glutamine, and taurine
  • Includes milk thistle and NAC
  • Adds standardized curcuminoids

Cons

  • Many ingredients are modestly dosed
  • Several extracts lack standardization
  • Not focused on one clear need

Warnings

  • Alpha-lipoic acid may add to glucose-lowering effects from insulin or diabetes medicines.
  • Turmeric and grape seed may increase bleeding tendency with anticoagulant or antiplatelet medicines.

Nutrient quality

56 Moderate impact

Several extracts name a target fraction, but standardization percentages and absorption support are missing. Most amino acids, NAC, botanicals, and antioxidants are well below common standalone amounts.

Ingredient transparency

76 High impact

Every listed active has an individual amount. Excipients and daily directions are absent from the supplied data, which leaves some label details uncertain.

Customer satisfaction

66 High impact

The aggregate satisfaction average is strong, though no detailed feedback is supplied. The available volume is useful but not extensive.

Value for money

30 Situational impact

The formula is coherent, yet weak dose depth limits the quality delivered per serving. The serving cost is high relative to the modest amounts.

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Goals

Detoxification
Detoxification
Impact
Moderate effect
A- Goal FitF Strength of SupportC+ CoverageD+ Formula Quality
Milk Thistle · 200 mgGlutamine · 250 mgTaurine · 250 mgGlycine · 250 mg

Milk thistle, NAC, glycine, taurine, glutamine, curcumin, and alpha-lipoic acid reach many relevant detoxification pathways. The ingredient selection is more purposeful than a generic greens cleanse.

Most actives are too lightly dosed for strong pathway depth, and key extracts lack standardization. The crowded formula favors label breadth over meaningful exposure.

Study evidence
Glutamine Supportive 8 studies
Glycine Supportive 5 studies
Green Tea Disputed 16 studies
Milk Thistle Supportive 46 studies
Taurine Supportive 2 studies

Ingredients

IngredientAmount per serving
Glutamine
250 mg
Glycine
250 mg
Taurine
250 mg
Milk Thistle seed extract
200 mg
Curcuma longa rhizome extract (Total Curcuminoids)
 100 mg
N-Acetyl Cysteine
100 mg
Alpha Lipoic Acid
100 mg
Grape seed extract
50 mg
MSM
50 mg
Broccoli sprout powder
50 mg
Yellow Dock
50 mg
Schisandra berry extract
50 mg
Green Tea leaf extract (Catechins)
 25 mg
Gluten Free Adults 18–50 Dairy Free Sugar Free
Report overview
Glycine · 250 mg OverallScore64
C Active Ingredient Quality & BioavailabilityC+ Dose, Safety & Label TransparencyB- Value

The glycine amount is clear, but no premium grade, branded source, or purity certification is provided. Its 250 mg contribution is modest alone but works as part of the multi-active antioxidant formula. Other well-chosen actives improve formula-level value despite weak glycine-only economics.

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Taurine · 250 mg OverallScore44
C- Active Ingredient Quality & BioavailabilityD- Dose, Safety & Label TransparencyF Value

The taurine amount is modest and falls below the general-maintenance tier. Its grade, source, and independent testing are undisclosed, and the amount is stated only for two capsules. The many other actives drive the formula, leaving poor value for someone primarily seeking taurine.

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Glutamine · 250 mg OverallScore36
D+ Active Ingredient Quality & BioavailabilityF Dose, Safety & Label TransparencyF Value

The label uses generic glutamine wording and supplies only a very small amount. Reaching a targeted intake would require an impractical number of capsules. The complex detox blend is especially poor value when judged as a glutamine source.

View ingredientView products
Loading alternative details
85 Performance

Trancor

Metagenics
<p>Taurine is doubled to 500 mg, NAC is tripled to 300 mg, and decaffeinated green-tea extract reaches 150 mg. Magnesium and vitamin B6 add useful support, though milk thistle, turmeric, glycine, and glutamine are not included.</p>
83 Performance

Glutathione Booster

Carlson
<p>NAC, milk thistle, glutamine, glycine, glutathione, alpha-lipoic acid, selenium, and antioxidant vitamins closely match the original pathways. Glutamine, glycine, and glutathione amounts are modest, but the formula improves cofactor support and ingredient coherence.</p>
81 Performance

EstroSense

Natural Factors WS WomenSense
<p>Standardized green tea, curcuminoids, silymarin, calcium-D-glucarate, indole-3-carbinol, and DIM provide more specialized conjugation and antioxidant support. The hormone-metabolism focus is narrower, and it does not retain the original amino-acid blend.</p>
73 Budget

Liv-Gall Cleanse

Natural Factors HerbalFactors
<p>Milk thistle, artichoke, turmeric, and dandelion provide a focused liver and gallbladder blend at a much lower serving cost. It lacks the original amino acids and antioxidant cofactors, so the value comes from simplicity rather than pathway breadth.</p>
78 Budget

Active Liver

New Nordic
<p>Artichoke, silymarin, and turmeric are supplied in larger, clearly stated amounts while remaining less costly per serving. Amino acids, NAC, and alpha-lipoic acid are absent, making it a cleaner botanical alternative rather than a full replacement.</p>
75 Budget

Milk Thistle Liver Detox

Irwin Naturals
<p>Milk thistle, artichoke, dandelion, turmeric, and schisandra create broader botanical liver support for less per serving. The formula does not cover glutamine, glycine, taurine, or NAC, but offers better depth in its selected herbs.</p>
88 Value

Silymarin Complex

California Gold Nutrition
<p>A focused blend supplies 300 mg silymarin with dandelion, artichoke, turmeric, ginger, and piperine at very low serving cost. It gives up the original amino acids and NAC, but offers much stronger value for botanical liver support.</p>
86 Value

Silymarin Milk Thistle Extract 150 mg

NOW
<p>Milk-thistle extract and 700 mg turmeric provide far more depth in two of the original collections while costing much less per serving. The narrow formula omits amino acids and other antioxidants, so it fits users prioritizing these two botanicals.</p>
84 Value

Milk Thistle Phytosome 150 mg

Natural Factors HerbalFactors
<p>A phytosome form of silymarin is paired with dandelion, turmeric, and artichoke in a highly affordable serving. Broader amino-acid and antioxidant pathways are absent, but the delivery form and concise liver focus improve value.</p>
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Sources

Published studies used for the product analysis and the top-ranked studies for each ingredient and goal.

  1. Efficacy of glutamine supplementation in postoperative patients undergoing hepatic surgery: a systematic review and meta-analysis of randomized controlled trials.
    Meng X; Zhang M; Wang X · Clinics (Sao Paulo, Brazil) · 2026
    Meta-analysis1,198 participants18 studies pooledDetoxification forGlutamine
  2. Glutamine supplementation in preterm infants receiving parenteral nutrition leads to an early improvement in liver function.
    Wang Y; Cai W; Tao YX; Tang QY; Feng Y; Wu J · Asia Pacific journal of clinical nutrition · 2014
    Randomized trial30 participantsDetoxification forGlutamine
  3. Parenteral glutamine protects hepatic function during bone marrow transplantation.
    Brown SA; Goringe A; Fegan C; Davies SV; Giddings J; Whittaker JA; Burnett AK; Poynton CH · Bone marrow transplantation · 1998
    Randomized trial34 participantsDetoxification forGlutamine
  4. Protective effect of parenteral glutamine supplementation on hepatic function in very low birth weight infants.
    Wang Y; Tao YX; Cai W; Tang QY; Feng Y; Wu J · Clinical nutrition (Edinburgh, Scotland) · 2010
    Randomized trial30 participantsDetoxification forGlutamine
  5. A multistrain probiotic increases the serum glutamine/glutamate ratio in patients with cirrhosis: a metabolomic analysis.
    Laghi L; Román E; Lan Q; Nieto JC; Canalda-Baltrons A; Poca M; Sánchez-Rodríguez MB; Clària J; Alvarado E; Cuyàs B; Sánchez E; Vidal S; Guarner C; Escorsell À; Manichanh C; Soriano G · Hepatology communications · 2023
    Randomized trial32 participantsDetoxification forGlutamine
  6. The impact of obesity-associated glycine deficiency on the elimination of endogenous and exogenous metabolites via the glycine conjugation pathway.
    Tan HC; Hsu JW; Tai ES; Chacko S; Kovalik JP; Jahoor F · Frontiers in endocrinology · 2024
    Cohort study42 participantsDetoxification forGlycine
  7. Metabolic impact of dietary glycine supplementation in individuals with severe obesity.
    Tan HC; Hsu JW; Tai ES; Chacko S; Wu V; Yen PM; Kovalik JP; Jahoor F · Scientific reports · 2025
    Single-arm trial19 participantsDetoxification forGlycine
  8. Contribution towards a Metabolite Profile of the Detoxification of Benzoic Acid through Glycine Conjugation: An Intervention Study.
    Irwin C; van Reenen M; Mason S; Mienie LJ; Westerhuis JA; Reinecke CJ · PloS one · 2017
    Non-randomized trial21 participantsDetoxification forGlycine
  9. Glycine conjugation of para-aminobenzoic acid (PABA): a quantitative test of liver function.
    Furuya KN; Durie PR; Roberts EA; Soldin SJ; Verjee Z; Yung-Jato L; Giesbrecht E; Ellis L · Clinical biochemistry · 1996
    Methods validation study74 participantsDetoxification forGlycine
  10. The treatment of isovaleric acidemia with glycine supplement
    M Naglak, R Salvo, K Madsen, P Dembure, L Elsas · Pediatric research · 1988
    Non-randomized trial2 participantsDetoxification forGlycine
  11. Therapeutic benefits of green tea extract on various parameters in non-alcoholic fatty liver disease patients.
    Hussain M; Habib-Ur-Rehman; Akhtar L · Pakistan journal of medical sciences · 2024
    Randomized trial80 participantsDetoxification forGreen Tea
  12. The Effect of Green Tea Extract Supplementation on Liver Enzymes in Patients with Nonalcoholic Fatty Liver Disease.
    Pezeshki A; Safi S; Feizi A; Askari G; Karami F · International journal of preventive medicine · 2016
    Randomized trial80 participantsDetoxification forGreen Tea
  13. Green tea with high-density catechins improves liver function and fat infiltration in non-alcoholic fatty liver disease (NAFLD) patients: a double-blind placebo-controlled study.
    Sakata R; Nakamura T; Torimura T; Ueno T; Sata M · International journal of molecular medicine · 2014
    Randomized trial17 participantsDetoxification forGreen Tea
  14. Green tea consumption is associated with decreased DNA damage among GSTM1-positive smokers regardless of their hOGG1 genotype.
    Hakim IA; Chow HH; Harris RB · The Journal of nutrition · 2008
    Randomized trialDetoxification forGreen Tea
  15. Modulation of human glutathione s-transferases by polyphenon e intervention.
    Chow HH; Hakim IA; Vining DR; Crowell JA; Tome ME; Ranger-Moore J; Cordova CA; Mikhael DM; Briehl MM; Alberts DS · Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology · 2007
    Single-arm trial42 participantsDetoxification forGreen Tea
  16. The effect of silymarin on liver enzymes in patients taking isotretinoin: A randomized clinical trial.
    Mirnezami M; Jafarimanesh H; Rezagholizamenjany M; Alimoradian A; Ranjbaran M · Dermatologic therapy · 2021
    Randomized trial74 participantsDetoxification forMilk Thistle
  17. A randomized double-blind, placebo-controlled study of therapeutic effects of silymarin in β-thalassemia major patients receiving desferrioxamine.
    Moayedi B; Gharagozloo M; Esmaeil N; Maracy MR; Hoorfar H; Jalaeikar M · European journal of haematology · 2013
    Randomized trial97 participantsDetoxification forMilk Thistle
  18. Effect of aerobic training with silymarin consumption on glycemic indices and liver enzymes in men with type 2 diabetes.
    Ghalandari K; Shabani M; Khajehlandi A; Mohammadi A · Archives of physiology and biochemistry · 2023
    Randomized trial60 participantsDetoxification forMilk Thistle
  19. Impact of silymarin-supplemented cookies on liver enzyme and inflammatory markers in non-alcoholic fatty liver disease patients.
    Jaffar HM; Bader Ul Ain H; Tufail T; Hanif A; Malik T · Food science & nutrition · 2024
    Clinical trial64 participantsDetoxification forMilk Thistle
  20. Impact of Silymarin Supplements on Liver Enzyme Levels: A Systematic Review.
    Calderon Martinez E; Herrera D; Mogan S; Hameed Z; Jangda AA; Khan TJ; Mroke P; Sajid S; Shah YR; Baig I · Cureus · 2023
    Systematic review3,846 participants29 studies pooledDetoxification forMilk Thistle
  21. Dietary amino acid taurine ameliorates liver injury in chronic hepatitis patients.
    Hu YH; Lin CL; Huang YW; Liu PE; Hwang DF · Amino acids · 2008
    Non-randomized trial24 participantsDetoxification forTaurine
  22. Taurine status and response to intravenous taurine supplementation in adults with short-bowel syndrome undergoing long-term parenteral nutrition: a pilot study.
    Schneider SM; Joly F; Gehrardt MF; Badran AM; Myara A; Thuillier F; Coudray-Lucas C; Cynober L; Trivin F; Messing B · The British journal of nutrition · 2006
    Single-arm trial32 participantsDetoxification forTaurine