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Vitamin C Powder 5000 mg

4.3
★ ★ ★ ★ ★
(60 ratings)
Vitamin C 5000 mg
Calcium 610 mg
Product Image
Score69
A clean buffered vitamin C powder with flexible measuring. The full 5,000 mg serving is excessive for routine use and may be difficult to tolerate.
How scoring works
Powder
Quantity:8 Liquid(s) • (37 servings)
Goals:
Immunity
Skin Health
General Health

Score 69

A clean buffered vitamin C powder with flexible measuring. The full 5,000 mg serving is excessive for routine use and may be difficult to tolerate.
How scoring works
$22.89($0.61 per serving)
iHerb
$ 22.89
Vitacost
$ 22.89
Walmart
$ 22.89
Pure Formulas
$ 22.89
Report prices

Analysis

Calcium ascorbate is a buffered form that some people may find gentler than plain ascorbic acid. The simple two-ingredient profile is easy to understand, and the powder allows serving adjustment.

A full serving supplies 5,000 mg of vitamin C and 610 mg of calcium. Those amounts make the labeled serving unnecessarily aggressive for routine supplementation and reduce flexibility for users already taking calcium.

The product is most sensible for people who specifically want a customizable buffered powder and plan to measure smaller servings. It is a poor fit for anyone seeking a moderate maintenance dose or taking other high-calcium products.

Who is it for
  • People who specifically prefer calcium ascorbate
  • Users comfortable measuring a smaller powder serving
Best for
  • Customizable buffered vitamin C dosing
  • Avoiding plain ascorbic acid

Pros

  • Single clearly identified vitamin C form
  • Buffered with calcium
  • Powder allows dose adjustment
  • No proprietary blend

Cons

  • Full serving is extremely large
  • Adds a substantial calcium amount
  • Poor fit for moderate daily dosing
  • Liquid-form labeling for a powder may be confusing

Warnings

  • A 5,000 mg vitamin C serving can cause diarrhea, cramping, or nausea.
  • The 610 mg calcium contribution should be considered by people with high calcium intake or calcium-related medical concerns.
  • People prone to kidney stones should discuss very high vitamin C intake with a qualified clinician.

Nutrient quality

64 Moderate impact

Buffered calcium ascorbate is a favorable and focused ingredient choice. The unusually large serving weakens dose quality and tolerability.

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Ingredient transparency

83 Highest impact

The active formula is simple, specific, and fully quantified. Missing measuring directions and non-active ingredients leave practical label gaps.

.

Customer satisfaction

60 Moderate impact

The aggregate rating is good but not exceptional and supported by a limited feedback count. No complaint-level evidence was supplied to identify recurring issues or confirm purpose-specific experiences.

.

Value for money

66 High impact

The focused formula avoids low-value extras and uses a buffered form. An oversized serving limits cost efficiency because much of the dose may offer little added benefit.

.
Report analysis

Goals

Immunity
Immunity
Impact
High effect
A Goal FitC Strength of SupportC- CoverageA Formula Quality
Vitamin C · 5000 mg

Calcium ascorbate provides a fully buffered vitamin C form with clear elemental calcium disclosure. Vitamin C directly supports immune-cell function and antioxidant protection.

The very large serving greatly exceeds efficient absorption needs and may cause diarrhea or abdominal discomfort. A much smaller measured amount would fit routine immune support better, but the supplied serving itself is poorly balanced.

Study evidence
Vitamin C Supportive 53 studies
Skin Health
Skin Health
Impact
High effect
B Goal FitC Strength of SupportD CoverageA- Formula Quality
Vitamin C · 5000 mg

Buffered calcium ascorbate directly supports collagen synthesis and antioxidant defense. The powder clearly identifies both vitamin C and its accompanying calcium.

The serving provides far more vitamin C than the body absorbs efficiently at one time. Such a large amount may cause diarrhea or stomach cramping, so a much smaller measured serving would be more practical.

Study evidence
Vitamin C Supportive 53 studies
General Health
General Health
Impact
High effect
B+ Goal FitC- Strength of SupportD- CoverageB Formula Quality
Vitamin C · 5000 mg

Calcium ascorbate provides a fully buffered vitamin C source with clear mineral disclosure. Vitamin C has an established role in antioxidant defense, immune function, and collagen formation.

The 5,000 mg labeled serving greatly exceeds routine needs and may cause diarrhea or abdominal discomfort. A smaller measured portion would be more practical, but the supplied serving directions make dose control awkward.

Study evidence
Vitamin C Supportive 56 studies
Bone Health
Bone Health
Impact
Moderate effect
B- Goal FitC+ Strength of SupportD- CoverageB- Formula Quality
Calcium · 610 mgVitamin C · 5000 mg

Calcium ascorbate supplies a large calcium amount alongside vitamin C, which supports collagen formation. The two ingredients address both mineral and organic-matrix needs, but calcium exceeds the most efficient single-dose range.

Vitamin D, vitamin K, magnesium, and trace minerals are absent, limiting calcium use and distribution support. The very large vitamin C amount may cause diarrhea, and calcium should be separated from levothyroxine and tetracycline or quinolone antibiotics.

Study evidence
Calcium Supportive 144 studies
Vitamin C Supportive 46 studies
Anti-Inflammatory Support
Anti-Inflammatory Support
Impact
Moderate effect
B- Goal FitC- Strength of SupportF CoverageA Formula Quality
Vitamin C · 5000 mg

Buffered calcium ascorbate provides direct antioxidant support that may help limit oxidative inflammatory stress. The very large serving exceeds efficient absorption needs and may cause osmotic diarrhea.

The disclosed 5000 mg amount gives the main antioxidant pathway meaningful depth. The single-antioxidant formula is lean but does not cover multiple inflammatory pathways..

Study evidence
Vitamin C Supportive 50 studies
Vision Support
Vision Support
Impact
Moderate effect
C Goal FitD Strength of SupportF CoverageB Formula Quality
Vitamin C · 5000 mg

Vitamin C provides ocular antioxidant support, but the product lacks other core vision nutrients. The calcium ascorbate form is buffered and clearly disclosed.

The very large amount exceeds efficient absorption needs and may cause diarrhea or stomach upset. A lower measured serving would be more practical, while carotenoid and structural-lipid pathways remain absent.

Study evidence
Vitamin C Disputed 24 studies

Ingredients

IngredientAmount per serving
Vitamin C (Calcium Ascorbate)
 5000 mg
Calcium (Calcium Ascorbate)
 610 mg
Adults 18–50
Report overview
Vitamin C (Calcium Ascorbate) · 5000 mg OverallScore75
B+ Active Ingredient Quality & BioavailabilityC+ Dose, Safety & Label TransparencyB+ Value

Buffered calcium ascorbate is gentle on the stomach and clearly identifies its accompanying calcium. The very large serving exceeds efficient absorption needs and may cause osmotic diarrhea. Cost per gram is favorable, but a much smaller measured serving would be more practical for routine use.

View ingredientView products
Calcium (Calcium Ascorbate) · 610 mg OverallScore70
A- Active Ingredient Quality & BioavailabilityC Dose, Safety & Label TransparencyD+ Value

Calcium ascorbate is a soluble form, though less established than premium bone-mineral forms. The 610 mg serving exceeds the most efficient single-dose absorption range. Calcium can reduce absorption of levothyroxine and tetracycline or quinolone antibiotics, so doses should be separated.

View ingredientView products
Loading alternative details
82 Performance

Liposomal Vitamin C 1000 mg

SunLipid
Buffered sodium ascorbate, a disclosed phospholipid complex, and MCT create a more purposeful delivery system at a moderate vitamin C amount. The sodium contribution may matter on a strict sodium limit, but the dose is more practical than the original very large calcium ascorbate serving.
89 Performance

Pure Buffered Calcium Ascorbate

NOW
Buffered calcium ascorbate preserves the original product's two core nutrients at a much more practical vitamin C amount. Clear active dosing and favorable serving value improve usability, though complete directions and inactive ingredients are not supplied.
82 Performance

Meta-C 1000 mg Tablets

NutriBiotic Immunity
Meta-C combines buffered vitamin C, calcium, and named metabolites in a moderate serving with strong disclosure. Spirulina adds limited clarity, but the formula is easier to use routinely than the original high-dose powder.
87 Budget

100% Pure Vitamin C Powder

Swanson Premium Brand
A flexible vitamin C powder provides a meaningful amount without the original product's unnecessarily large routine serving. Plain ascorbic acid is less buffered and supplies no calcium, but its clear formula and favorable serving value suit users without stomach sensitivity.
83 Budget

C 500 mg

21st Century
A moderate vitamin C tablet avoids the digestive burden that may accompany the original very large serving. The ascorbic acid form is basic and calcium is only a small addition, but the long supply offers strong practical value.
85 Budget

Gold C Vitamin C 1000 mg

California Gold Nutrition
A simple liquid provides a substantial vitamin C amount at favorable serving value while avoiding the original product's extreme dose. It is unbuffered and carrier details are missing, so sensitive users may still prefer a mineral ascorbate.
87 Value

Pure Buffered Magnesium Ascorbate

NOW
Fully buffered magnesium ascorbate offers a substantial vitamin C amount and a clearly disclosed mineral contribution at favorable serving value. It replaces calcium with magnesium, but the routine dose is more measured and likely easier to tolerate.
87 Value

C 500 mg

Mason Natural
A simple moderate-dose vitamin C tablet provides strong everyday value and avoids the original product's aggressive serving size. Generic ascorbic acid is not buffered and calcium is absent, so the value advantage comes with a simpler ingredient profile.
82 Value

C 500 mg

Swanson
A practical vitamin C amount and small rose hip extract provide focused support at a low serving cost. The formula is unbuffered and does not replace the original calcium contribution, but it is easier to fit into routine use.
Report alternatives

Sources

Published studies used for the product analysis and the top-ranked studies for each ingredient and goal.

  1. Calcium supplementation during pregnancy and maternal and offspring bone health: a systematic review and meta-analysis.
    Tihtonen K; Korhonen P; Isojärvi J; Ojala R; Ashorn U; Ashorn P; Tammela O · Annals of the New York Academy of Sciences · 2022
    Meta-analysis1,566 participants7 studies pooledBone Health forCalcium
  2. Calcium supplementation and bone mineral density in postmenopausal women using estrogen replacement therapy.
    Haines CJ; Chung TK; Leung PC; Hsu SY; Leung DH · Bone · 1995
    Randomized trialBone Health forCalcium
  3. Calcium supplementation provides an extended window of opportunity for bone mass accretion after menarche.
    Rozen GS; Rennert G; Dodiuk-Gad RP; Rennert HS; Ish-Shalom N; Diab G; Raz B; Ish-Shalom S · The American journal of clinical nutrition · 2003
    Randomized trial100 participantsBone Health forCalcium
  4. Relationship between bone mineral density changes and risk of fractures among patients receiving calcium with or without vitamin D supplementation: a meta-regression.
    Rabenda V; Bruyère O; Reginster JY · Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2011
    Meta-analysis47,365 participants15 studies pooledBone Health forCalcium
  5. Treatment with alendronate plus calcium, alendronate alone, or calcium alone for postmenopausal low bone mineral density.
    Bonnick S; Broy S; Kaiser F; Teutsch C; Rosenberg E; DeLucca P; Melton M · Current medical research and opinion · 2007
    Randomized trial701 participantsBone Health forCalcium
  6. Efficacy of Vitamin C as Glucocorticoid Substitute for Reducing Pain and Inflammation After Total Hip Arthroplasty: A Randomized Controlled Trial.
    Jiang W; Xu H; Jiang X; Zhan Y; Ju Y; Xie J; Huang Z; Huang Q; Pei F · The Journal of bone and joint surgery. American volume · 2025
    Randomized trial107 participantsAnti-Inflammatory Support forVitamin C
  7. The Impact of Vitamin C on Analgesic, Anti-inflammatory, and Hemostatic Outcomes After Total Hip and Knee Arthroplasty: A Systematic Review and Meta-Analysis.
    Moftakhari Hajimirzaei S; Bagherzadeh Cham M; Dolikhani M; Tabatabaee SM; Ebrahimpour A · The archives of bone and joint surgery · 2026
    Meta-analysis1,162 participants10 studies pooledAnti-Inflammatory Support forVitamin C
  8. The impact of vitamin C supplementation on the perioperative outcomes after total hip and knee arthroplasty: a systematic review and meta-analysis.
    Liu X; Guo J; Li Y; Yang Y; Liu M; Gao Q; Yang Y; Wu X; Yue C · BMC musculoskeletal disorders · 2026
    Meta-analysis852 participants8 studies pooledAnti-Inflammatory Support forVitamin C
  9. Therapeutic Impact of Ascorbic Acid on Oral and Periodontal Tissues: A Systematic Literature Review.
    Ruzijevaite G; Acaite E; Jagelaviciene E · Medicina (Kaunas, Lithuania) · 2025
    Systematic review811 participants17 studies pooledAnti-Inflammatory Support forVitamin C
  10. Oral vitamin C administration reduces early recurrence rates after electrical cardioversion of persistent atrial fibrillation and attenuates associated inflammation.
    Korantzopoulos P; Kolettis TM; Kountouris E; Dimitroula V; Karanikis P; Pappa E; Siogas K; Goudevenos JA · International journal of cardiology · 2005
    Randomized trial44 participantsAnti-Inflammatory Support forVitamin C
  11. What is the impact of daily oral supplementation of vitamin D3 (cholecalciferol) plus calcium on the incidence of hip fracture in older people? A systematic review and meta-analysis.
    Manoj P; Derwin R; George S · International journal of older people nursing · 2023
    Meta-analysis12,620 participants7 studies pooledBone Health forCalcium
  12. Calcium supplementation prevents seasonal bone loss and changes in biochemical markers of bone turnover in elderly New England women: a randomized placebo-controlled trial.
    Storm D; Eslin R; Porter ES; Musgrave K; Vereault D; Patton C; Kessenich C; Mohan S; Chen T; Holick MF; Rosen CJ · The Journal of clinical endocrinology and metabolism · 1998
    Randomized trial60 participantsBone Health forCalcium
  13. The effects of calcium supplementation (milk powder or tablets) and exercise on bone density in postmenopausal women.
    Prince R; Devine A; Dick I; Criddle A; Kerr D; Kent N; Price R; Randell A · Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research · 1995
    Randomized trial168 participantsBone Health forCalcium
  14. The efficacy of calcium supplementation alone in elderly Thai women over a 2-year period: a randomized controlled trial.
    Rajatanavin R; Chailurkit L; Saetung S; Thakkinstian A; Nimitphong H · Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2014
    Randomized trial404 participantsBone Health forCalcium
  15. Calcium-enriched foods and bone mass growth in prepubertal girls: a randomized, double-blind, placebo-controlled trial.
    Bonjour JP; Carrie AL; Ferrari S; Clavien H; Slosman D; Theintz G; Rizzoli R · The Journal of clinical investigation · 1997
    Randomized trial149 participantsBone Health forCalcium
  16. Can Dietary Intake of Vitamin C-Oriented Foods Reduce the Risk of Osteoporosis, Fracture, and BMD Loss? Systematic Review With Meta-Analyses of Recent Studies.
    Zeng LF; Luo MH; Liang GH; Yang WY; Xiao X; Wei X; Yu J; Guo D; Chen HY; Pan JK; Huang HT; Liu Q; Guan ZT; Han YH; Zhao D; Zhao JL; Hou SR; Wu M; Lin JT; Li JH; Liang WX; Ou AH; Wang Q; Li ZP; Liu J · Frontiers in endocrinology · 2020
    Meta-analysis19,484 participants17 studies pooledBone Health forVitamin C
  17. Dietary vitamin C intake and the risk of hip fracture: a dose-response meta-analysis.
    Sun Y; Liu C; Bo Y; You J; Zhu Y; Duan D; Cui H; Lu Q · Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2019
    Meta-analysis6 studies pooledBone Health forVitamin C
  18. Smoking, antioxidant vitamins, and the risk of hip fracture.
    Melhus H; Michaëlsson K; Holmberg L; Wolk A; Ljunghall S · Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research · 1999
    Cohort study66,651 participantsBone Health forVitamin C
  19. Micronutrients and the risk of hip fracture: Case-control study.
    Torbergsen AC; Watne LO; Wyller TB; Frihagen F; Strømsøe K; Bøhmer T; Mowe M · Clinical nutrition (Edinburgh, Scotland) · 2018
    Case-control study189 participantsBone Health forVitamin C
  20. Favorable effect of dietary vitamin C on bone mineral density in postmenopausal women (KNHANES IV, 2009): discrepancies regarding skeletal sites, age, and vitamin D status.
    Kim YA; Kim KM; Lim S; Choi SH; Moon JH; Kim JH; Kim SW; Jang HC; Shin CS · Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2016
    Cross-sectional study1,196 participantsBone Health forVitamin C
  21. Dietary intake and blood concentrations of antioxidants and the risk of cardiovascular disease, total cancer, and all-cause mortality: a systematic review and dose-response meta-analysis of prospective studies.
    Aune D; Keum N; Giovannucci E; Fadnes LT; Boffetta P; Greenwood DC; Tonstad S; Vatten LJ; Riboli E; Norat T · The American journal of clinical nutrition · 2019
    Meta-analysis69 studies pooledGeneral Health forVitamin C
  22. Scientific Opinion on the substantiation of a health claim related to vitamin C and increasing non haem iron absorption pursuant to Article 14 of Regulation (EC) No 1924/2006.
    EFSA Panel on Dietetic Products, Nutrition and Allergies (NDA) · EFSA journal. European Food Safety Authority · 2026
    Guideline / consensusGeneral Health forVitamin C
  23. Vitamin C Depletion and All-Cause Mortality in Renal Transplant Recipients.
    Sotomayor CG; Eisenga MF; Gomes Neto AW; Ozyilmaz A; Gans ROB; Jong WHA; Zelle DM; Berger SP; Gaillard CAJM; Navis GJ; Bakker SJ · Nutrients · 2018
    Cohort study598 participantsGeneral Health forVitamin C
  24. Associations of Serum Biomarkers of Fruit and Vegetable Intake With the Risk of Cause-Specific Mortality and All-Cause Mortality: A National Prospective Cohort Study.
    Pu L; Zhang R; Wang X; Zhao T; Sun H; Han L · Frontiers in nutrition · 2022
    Cohort study12,530 participantsGeneral Health forVitamin C
  25. Relation between plasma ascorbic acid and mortality in men and women in EPIC-Norfolk prospective study: a prospective population study. European Prospective Investigation into Cancer and Nutrition.
    Khaw KT; Bingham S; Welch A; Luben R; Wareham N; Oakes S; Day N · Lancet (London, England) · 2001
    Cohort study19,496 participantsGeneral Health forVitamin C
  26. Vitamin C and contribution to the normal function of the immune system: evaluation of a health claim pursuant to Article 14 of Regulation (EC) No 1924/2006.
    EFSA Panel on Dietetic Products, Nutrition and Allergies (NDA) · EFSA journal. European Food Safety Authority · 2026
    Guideline / consensusImmunity forVitamin C
  27. Therapeutic effects of high-dose vitamin C supplementation in patients with COVID-19: a meta-analysis.
    Sun L; Zhao JH; Fan WY; Feng B; Liu WW; Chen RQ; Ban C; Dang AG; Wang M; Luo KT; Zhou GY; Yu FF; Ba Y · Nutrition reviews · 2024
    Meta-analysis2,334 participants14 studies pooledImmunity forVitamin C
  28. Effect of micronutrient supplements on influenza and other respiratory tract infections among adults: a systematic review and meta-analysis.
    Abioye AI; Bromage S; Fawzi W · BMJ global health · 2021
    Meta-analysisImmunity forVitamin C
  29. New evidence for antioxidant properties of vitamin C.
    Vojdani A; Bazargan M; Vojdani E; Wright J · Cancer detection and prevention · 2001
    Randomized trial20 participantsImmunity forVitamin C
  30. Enhanced Vitamin C Delivery: A Systematic Literature Review Assessing the Efficacy and Safety of Alternative Supplement Forms in Healthy Adults.
    Calder PC; Kreider RB; McKay DL · Nutrients · 2025
    Systematic review13 studies pooledImmunity forVitamin C
  31. Evaluation of the anti-wrinkle effect of an ascorbic acid-loaded dissolving microneedle patch via a double-blind, placebo-controlled clinical study.
    Lee C; Yang H; Kim S; Kim M; Kang H; Kim N; An S; Koh J; Jung H · International journal of cosmetic science · 2017
    Randomized trial23 participantsSkin Health forVitamin C
  32. Comparative Study on the Outcome of Periorbital Wrinkles Treated with Laser-Assisted Delivery of Vitamin C or Vitamin C Plus Growth Factors: A Randomized, Double-blind, Clinical Trial.
    Machado BHB; Frame J; Zhang J; Najlah M · Aesthetic plastic surgery · 2021
    Randomized trial149 participantsSkin Health forVitamin C
  33. Randomized trial of topical ascorbic acid in DMSO versus imiquimod for the treatment of basal cell carcinoma.
    Burke B; Bailie JE · Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie · 2022
    Randomized trial25 participantsSkin Health forVitamin C
  34. Vitamin C improves healing of foot ulcers: a randomised, double-blind, placebo-controlled trial.
    Gunton JE; Girgis CM; Lau T; Vicaretti M; Begg L; Flood V · The British journal of nutrition · 2022
    Randomized trial16 participantsSkin Health forVitamin C
  35. Dietary nutrient intakes and skin-aging appearance among middle-aged American women.
    Cosgrove MC; Franco OH; Granger SP; Murray PG; Mayes AE · The American journal of clinical nutrition · 2007
    Cross-sectional study4,025 participantsSkin Health forVitamin C
  36. Role of Oral Vitamin 'C' on Astigmatic Errors in Phacoemulsification.
    Mohan S; Sah K; Khattri M; Ahmad L; Sachan SK · Current eye research · 2021
    Randomized trial400 participantsVision Support forVitamin C
  37. Ascorbic acid metabolites are involved in intraocular pressure control in the general population.
    Hysi PG; Khawaja AP; Menni C; Tamraz B; Wareham N; Khaw KT; Foster PJ; Benet LZ; Spector TD; Hammond CJ · Redox biology · 2019
    Observational studyVision Support forVitamin C
  38. Nutritional modulation of cataract.
    Weikel KA; Garber C; Baburins A; Taylor A · Nutrition reviews · 2014
    Narrative reviewVision Support forVitamin C
  39. Dietary n-3 Fatty Acid, α-Tocopherol, Zinc, vitamin D, vitamin C, and β-carotene are Associated with Age-Related Macular Degeneration in Japan.
    Aoki A; Inoue M; Nguyen E; Obata R; Kadonosono K; Shinkai S; Hashimoto H; Sasaki S; Yanagi Y · Scientific reports · 2017
    Case-control study530 participantsVision Support forVitamin C
  40. Adherence to a Mediterranean diet, lifestyle and age-related macular degeneration: the Coimbra Eye Study - report 3.
    Raimundo M; Mira F; Cachulo MDL; Barreto P; Ribeiro L; Farinha C; Laíns I; Nunes S; Alves D; Figueira J; Merle BM; Delcourt C; Santos L; Silva R · Acta ophthalmologica · 2019
    Case-control study883 participantsVision Support forVitamin C