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Yeast-Free Selenium 100 mcg L-Selenomethionine

Solgar
4.9
★ ★ ★ ★ ★
(20183 ratings)
Selenium 100 mcg
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Score86
Yeast-Free Selenium 100 mcg L-Selenomethionine offers a clearly identified, well-absorbed organic form at 100 mcg per serving. It fits targeted selenium use, but buyers seeking broader daily nutrient support will need a different formula.
How scoring works
Quantity:100 Tablet(s) • (100 servings)
Goals:
General Health
Immunity

Score 86

Yeast-Free Selenium 100 mcg L-Selenomethionine offers a clearly identified, well-absorbed organic form at 100 mcg per serving. It fits targeted selenium use, but buyers seeking broader daily nutrient support will need a different formula.
How scoring works
$6.79($0.06 per serving)
iHerb
$ 6.79
Pure Formulas
$ 7.19
Daily Vita
$ 7.91
Vitacost
$ 7.23
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Analysis

A 100 mcg serving provides a clearly identified, well-absorbed organic form in a focused selenium formula. The maintenance-oriented amount is clearly disclosed and suits people who have a specific reason to supplement selenium.

Selenium supports antioxidant enzymes, normal thyroid hormone conversion, and immune function. The single-active formula is easy to understand, but it does not cover the broader nutrient pathways involved in general wellness or immune support.

100 servings and very efficient serving value make the format practical for consistent use. The moderate amount leaves more room for selenium from food than a higher-dose product, while combined intake still deserves attention.

Who is it for
  • Adults seeking a 100 mcg selenium supplement
  • People who prefer tablets for routine use
  • Users who want a simple, single-active formula
Best for
  • Targeted selenium supplementation
  • Antioxidant enzyme support
  • Normal thyroid and immune function support

Pros

  • 100 mcg selenium amount is fully disclosed
  • L-Selenomethionine clearly identifies the active form
  • 100 servings per container support routine use
  • Very efficient serving value

Cons

  • The supplied label details do not describe inactive ingredients or other formulation features.
  • The focused formula does not provide vitamin D, zinc, vitamin C, or other complementary nutrients.
  • The maintenance amount may be less suitable for someone specifically advised to use a higher dose.

Warnings

  • The 100 mcg selenium serving is moderate; include other selenium supplements when calculating total daily intake.
  • Frequent Brazil-nut intake or another selenium-rich product can materially increase the total alongside this 100 mcg serving.
  • Persistent hair or nail changes, a metallic taste, or a garlic-like breath odor can signal excessive selenium intake and warrant stopping use and seeking advice.

Nutrient quality

94 Highest impact

The focused selenium formula provides a meaningful amount for antioxidant, thyroid, and immune support. Form quality and dose balance determine the main strengths and trade-offs.

Ingredient transparency

82 Highest impact

The active amount is clearly disclosed without a hidden blend. Intake directions and non-active ingredients are not included, while form specificity varies by product.

Customer satisfaction

74 High impact

The aggregate rating is favorable and the response base provides useful context. No review text is supplied, so repeated complaints and specific product experiences cannot be verified.

Value for money

91 Highest impact

The formula provides meaningful selenium at a reasonable ongoing cost. Form quality and focused design support competitive category value.

Report analysis

Goals

General Health
Impact
Highest effect
A- Goal FitA Strength of SupportC CoverageA+ Formula Quality
Selenium · 100 mcg

Selenium supports antioxidant enzymes, thyroid hormone conversion, and immune function, giving it a sound foundational role. L-selenomethionine is a clearly identified and well-absorbed form.

The maintenance serving leaves a broad safety margin for most adults. Coverage is intentionally narrow, but the single active is strong and fully disclosed.

Study evidence
Selenium Supportive 70 studies
Immunity
Impact
High effect
B- Goal FitA Strength of SupportD+ CoverageA+ Formula Quality
Selenium · 100 mcg

Selenium supports antioxidant enzymes that help protect normal immune function. The focused serving is most relevant when dietary selenium intake is low.

L-selenomethionine is a clearly identified, well-absorbed organic selenium form. The narrow formula does not replace direct immune nutrients such as vitamin D, zinc, or vitamin C.

Study evidence
Selenium Mixed 37 studies

Ingredients

IngredientAmount per serving
Selenium (L-Selenomethionine)
100 mcg
Gluten Free Adults 18–50 Vegan Kosher Dairy Free Sugar Free Vegetarian
Report overview
A+ Active Ingredient Quality & BioavailabilityA- Dose, Safety & Label TransparencyB+ Value

L-selenomethionine provides a clearly identified, highly bioavailable organic form. The 100 mcg amount is suitable for daily maintenance and leaves a broad safety margin. Its standardized cost provides good value rather than the lowest-cost tier.

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Sources

Published studies used for the product analysis and the top-ranked studies for each ingredient and goal.

  1. Selenium intake and multiple health-related outcomes: an umbrella review of meta-analyses.
    Wang P; Chen B; Huang Y; Li J; Cao D; Chen Z; Li J; Ran B; Yang J; Wang R; Wei Q; Dong Q; Liu L · Frontiers in nutrition · 2024
    Systematic reviewGeneral Health forSelenium
  2. Mortality in randomized trials of antioxidant supplements for primary and secondary prevention: systematic review and meta-analysis.
    Bjelakovic G; Nikolova D; Gluud LL; Simonetti RG; Gluud C · JAMA · 2007
    Meta-analysis232,606 participants68 studies pooledGeneral Health forSelenium
  3. Effect of long-term selenium supplementation on mortality: Results from a multiple-dose, randomised controlled trial.
    Rayman MP; Winther KH; Pastor-Barriuso R; Cold F; Thvilum M; Stranges S; Guallar E; Cold S · Free radical biology & medicine · 2019
    Randomized trial491 participantsGeneral Health forSelenium
  4. Selenium and immune function: a systematic review and meta-analysis of experimental human studies.
    Filippini T; Fairweather-Tait S; Vinceti M · The American journal of clinical nutrition · 2023
    Meta-analysis9 studies pooledImmunity forSelenium
  5. Selenium supplementation has beneficial and detrimental effects on immunity to influenza vaccine in older adults.
    Ivory K; Prieto E; Spinks C; Armah CN; Goldson AJ; Dainty JR; Nicoletti C · Clinical nutrition (Edinburgh, Scotland) · 2018
    Randomized trial117 participantsImmunity forSelenium
  6. Humoral immune response to COVID-19 mRNA vaccination in relation to selenium status.
    Demircan K; Chillon TS; Sun Q; Heller RA; Klingenberg GJ; Hirschbil-Bremer IM; Seemann P; Diegmann J; Bachmann M; Moghaddam A; Schomburg L · Redox biology · 2022
    Cohort study126 participantsImmunity forSelenium
  7. Associations of selenium status with all-cause and cause-specific mortality: a systematic review and meta-analysis of cohort studies.
    Cui Z; Xie R; Lu X; Schomburg L; Brenner H; Schöttker B · Redox biology · 2025
    Meta-analysis95 participants20 studies pooledGeneral Health forSelenium
  8. Dietary Antioxidants, Circulating Antioxidant Concentrations, Total Antioxidant Capacity, and Risk of All-Cause Mortality: A Systematic Review and Dose-Response Meta-Analysis of Prospective Observational Studies.
    Jayedi A; Rashidy-Pour A; Parohan M; Zargar MS; Shab-Bidar S · Advances in nutrition (Bethesda, Md.) · 2019
    Meta-analysis507,251 participants41 studies pooledGeneral Health forSelenium
  9. The efficacy and safety of selenium supplementation versus placebo in the treatment of Graves' orbitopathy: A systematic review and meta-analysis of randomised controlled trials.
    Sharabati I; Qafesha RM; Hindawi MD; Amro S; Ayesh BM · Clinical endocrinology · 2024
    Meta-analysis4 studies pooledGeneral Health forSelenium
  10. Associations of plasma metal concentrations with the risks of all-cause and cardiovascular disease mortality in Chinese adults.
    Shi L; Yuan Y; Xiao Y; Long P; Li W; Yu Y; Liu Y; Liu K; Wang H; Zhou L; Yang H; Li X; He M; Wu T · Environment international · 2021
    Cohort study6,155 participantsGeneral Health forSelenium
  11. Updates on clinical studies of selenium supplementation in radiotherapy.
    Puspitasari IM; Abdulah R; Yamazaki C; Kameo S; Nakano T; Koyama H · Radiation oncology (London, England) · 2015
    Systematic review16 studies pooledGeneral Health forSelenium
  12. Effects of selenium supplementation on selenoprotein gene expression and response to influenza vaccine challenge: a randomised controlled trial.
    Goldson AJ; Fairweather-Tait SJ; Armah CN; Bao Y; Broadley MR; Dainty JR; Furniss C; Hart DJ; Teucher B; Hurst R · PloS one · 2011
    Randomized trial119 participantsImmunity forSelenium
  13. Effect of selenium on immune response against hepatitis B vaccine with accelerated method in insulin-dependent diabetes mellitus patients.
    Janbakhsh A; Mansouri F; Vaziri S; Sayad B; Afsharian M; Rahimi M; Shahebrahimi K; Salari F · Caspian journal of internal medicine · 2013
    Randomized trial62 participantsImmunity forSelenium
  14. Chemoprevention trial of human hepatitis with selenium supplementation in China.
    Yu SY; Li WG; Zhu YJ; Yu WP; Hou C · Biological trace element research · 1990
    Non-randomized trial20,847 participantsImmunity forSelenium
  15. Selenium nanoparticles as adjunctive therapy in sepsis: A pilot randomized clinical trial.
    Gu WJ; Huang W; Zhao FZ; Yuan XK; Jin K; Chen JL; Zhang CY; Huang Y; He L; Zhuang H; Yin HY; Chen T · Drug resistance updates : reviews and commentaries in antimicrobial and anticancer chemotherapy · 2026
    Randomized trial70 participantsImmunity forSelenium
  16. Selenium supplementation in patients with autoimmune thyroiditis decreases thyroid peroxidase antibodies concentrations.
    Gärtner R; Gasnier BC; Dietrich JW; Krebs B; Angstwurm MW · The Journal of clinical endocrinology and metabolism · 2002
    Randomized trial70 participantsImmunity forSelenium