600 + D3 plus Minerals

600 + D3 plus Minerals

21st Century4.8 (1,665 ratings)
Format:Tablet Quantity: 120 Tablet(s) · 120 servings
Goals
$5.49 $0.04 per serving

Product analysis

68 out of 100

600 + D3 plus Minerals combines calcium and vitamin D to help fill nutritional gaps that matter for normal bone health. Copper oxide is a weak choice for absorption, which limits the appeal of the added minerals.

AI assessment of the formula, label and price. How scoring works

Nutrient Quality36

Calcium carbonate offers moderate absorption potential, while copper oxide is a weak choice for absorption. The quality of the other named mineral sources remains uncertain.

Ingredient Transparency100

Amounts and forms are disclosed for all listed ingredients. That makes the mineral sources and serving contents straightforward to compare.

Value For Money60

The low serving cost is favorable when buying the formula for calcium or copper. Value for the other nutrients remains uncertain, and the low cost does not resolve the copper form’s limitations.

Customer Satisfaction86

Customer feedback is very favorable across a substantial number of ratings. Those ratings describe satisfaction without establishing bone benefits.

Product Focus82

Calcium and vitamin D give the formula a clear bone-health purpose, especially when nutritional intake is low. The small magnesium contribution and added trace minerals do not establish extra bone benefits when needs are already met.

Format
Tablet
Container
120 Tablet(s)
Per serving
$0.04
Customer rating
4.8 · 1,665 ratings
Report analysis

Goals

Bone Health
Impact
Highest effect
B Ingredient FitC PathwaysA+ EvidenceA+ Formulation Logic
Magnesium · 50 mgCalcium · 600 mgVitamin D · 20 mcgCopper · 1 mgManganese · 1.8 mgBoron · 250 mcgZinc · 7.5 mg
Study evidence
Boron Supportive 5 studies
Calcium Supportive 144 studies
Copper Disputed 20 studies
Magnesium Supportive 48 studies
Manganese Adverse 12 studies
Vitamin D Supportive 202 studies
Zinc Supportive 33 studies

Ingredients

IngredientAmount per servingScore
Vitamin D3 (Cholecalciferol)
20 mcg
Calcium (Calcium Carbonate)
600 mg 70
Magnesium (Magnesium Oxide)
50 mg
Zinc (Zinc Oxide)
7.5 mg
Copper (Copper Oxide)
1 mg 60
Manganese (Manganese Sulfate)
1.8 mg
Boron (Sodium Borate)
250 mcg
Gluten Free Adults 18–50
Report overview
C+ Active Ingredient Quality & BioavailabilityC Dose, Safety & Label TransparencyA+ Value
The serving provides 600 mg of calcium per serving at a low cost per serving. It uses Calcium Carbonate. The Other Ingredients include an artificial additive.
How this ingredient is rated

Active Ingredient Quality & Bioavailability65

It uses Calcium Carbonate. The calcium amount is stated.
Calcium Form & Absorption Potential
It uses Calcium Carbonate.
Elemental Calcium Transparency
The calcium amount is stated as 600 mg per serving.

Dose, Safety & Label Transparency60

The serving provides 600 mg of calcium. That provides a substantial amount. The Other Ingredients include an artificial additive.
Absorption-Optimized Serving Dose
The serving provides 600 mg of calcium. That provides a substantial amount.
Formulation Purity & Additives
The Other Ingredients include an artificial additive.

Value100

The cost per serving is low.
Price Per Serving Efficiency
The cost per serving is low.
F Active Ingredient Quality & BioavailabilityB- Dose, Safety & Label TransparencyA+ Value
The serving provides 1 mg of copper. The cost per serving is low. Copper Oxide has very poor copper availability in humans.
How this ingredient is rated

Active Ingredient Quality & Bioavailability30

Copper Oxide has very poor copper availability in humans.
Copper Form Bioavailability
Copper Oxide has very poor copper availability in humans.
Elemental Copper Labeling Clarity
The label states the copper amount and names copper oxide.

Dose, Safety & Label Transparency71

The serving provides 1 mg of copper. The serving also provides 7.5 mg of zinc.
Copper Dosage Safety & Efficacy
The serving provides 1 mg of copper.
Zinc-to-Copper Balance
The serving also provides 7.5 mg of zinc.

Value100

The cost per serving is low.
Price Per Serving Efficiency
The cost per serving is low.
Report alternatives

Sources

Published studies used for the product analysis and the top-ranked studies for each ingredient and goal.

  1. [Comparative study of the urinary excretion of boron, calcium, magnesium and phosphorus in postmenopausal women with and without osteoporosis].
    José Ramón V; Mora Mora M; Marino Alarcón O; Hernández G; Josefina Linares L; Urdaneta Romero H; Arévalo González E · Investigacion clinica · 2013
    Case-control study45 participantsBone Health forBoron
  2. Effect of dietary boron on mineral, estrogen, and testosterone metabolism in postmenopausal women.
    Nielsen FH; Hunt CD; Mullen LM; Hunt JR · FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 1987
    Single-arm trial12 participantsBone Health forBoron
  3. The relationship between boron and magnesium status and bone mineral density in the human: a review.
    Volpe SL; Taper LJ; Meacham S · Magnesium research · 1994
    Narrative reviewBone Health forBoron
  4. Effects of boron supplementation on bone mineral density and dietary, blood, and urinary calcium, phosphorus, magnesium, and boron in female athletes.
    Meacham SL; Taper LJ; Volpe SL · Environmental health perspectives · 1995
    Randomized trial28 participantsBone Health forBoron
  5. Metabolic responses of postmenopausal women to supplemental dietary boron and aluminum during usual and low magnesium intake: boron, calcium, and magnesium absorption and retention and blood mineral concentrations
    C D Hunt, J L Herbel, F H Nielsen · The American Journal of Clinical Nutrition · 1997
    Non-randomized trial11 participantsBone Health forBoron
  6. What is the impact of daily oral supplementation of vitamin D3 (cholecalciferol) plus calcium on the incidence of hip fracture in older people? A systematic review and meta-analysis.
    Manoj P; Derwin R; George S · International journal of older people nursing · 2023
    Meta-analysis12,620 participants7 studies pooledBone Health forCalcium
  7. Calcium supplementation prevents seasonal bone loss and changes in biochemical markers of bone turnover in elderly New England women: a randomized placebo-controlled trial.
    Storm D; Eslin R; Porter ES; Musgrave K; Vereault D; Patton C; Kessenich C; Mohan S; Chen T; Holick MF; Rosen CJ · The Journal of clinical endocrinology and metabolism · 1998
    Randomized trial60 participantsBone Health forCalcium
  8. The effects of calcium supplementation (milk powder or tablets) and exercise on bone density in postmenopausal women.
    Prince R; Devine A; Dick I; Criddle A; Kerr D; Kent N; Price R; Randell A · Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research · 1995
    Randomized trial168 participantsBone Health forCalcium
  9. The efficacy of calcium supplementation alone in elderly Thai women over a 2-year period: a randomized controlled trial.
    Rajatanavin R; Chailurkit L; Saetung S; Thakkinstian A; Nimitphong H · Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2014
    Randomized trial404 participantsBone Health forCalcium
  10. Calcium-enriched foods and bone mass growth in prepubertal girls: a randomized, double-blind, placebo-controlled trial.
    Bonjour JP; Carrie AL; Ferrari S; Clavien H; Slosman D; Theintz G; Rizzoli R · The Journal of clinical investigation · 1997
    Randomized trial149 participantsBone Health forCalcium
  11. The Association between Dietary and Circulating Copper Levels and Osteoporosis: a Scoping Review.
    Ju Y; Xiong W; Pang Y; Chen Z; Hou J; Zheng S; Li Z; Liu T; Xia H; Xia M; Zhong Y; Li J; Jiang X · Biological trace element research · 2026
    Scoping review18 studies pooledBone Health forCopper
  12. Association between dietary copper, iron, zinc, selenium intake and osteopenia or osteoporosis in elderly hypertensive patients: a retrospective cohort study.
    Chen M; Jia L; Gao R · Frontiers in nutrition · 2024
    Cohort study5,286 participantsBone Health forCopper
  13. Associations of dietary copper intake with total bone mineral density and lumbar spine bone mineral density in American adults.
    Hu M; Wang Z; Li C; Zheng Y; Hu J · Medicine · 2025
    Cross-sectional studyBone Health forCopper
  14. The association between dietary mineral intake and bone mineral density: a cross-sectional study.
    Wei M; Wei J; Huang S · Journal of health, population, and nutrition · 2025
    Cross-sectional study11,520 participantsBone Health forCopper
  15. Association between dietary copper intake and bone mineral density in children and adolescents aged 8-19 years: A cross-sectional study.
    Cui A; Yan J; Li H; Fan Z; Wei X; Wang H; Zhuang Y · PloS one · 2024
    Cross-sectional study6,965 participantsBone Health forCopper
  16. Association between Serum Magnesium and Fractures: A Systematic Review and Meta-Analysis of Observational Studies.
    Dominguez LJ; Veronese N; Ciriminna S; Pérez-Albela JL; Vásquez-López VF; Rodas-Regalado S; Di Bella G; Parisi A; Tagliaferri F; Barbagallo M · Nutrients · 2023
    Meta-analysis119,755 participants4 studies pooledBone Health forMagnesium
  17. Bioabsorbable Magnesium-Based Materials Potential and Safety in Bone Surgery: A Systematic Review.
    Hung CH; Kwok YC; Yip J; Wong HH; Leung YY · Craniomaxillofacial trauma & reconstruction · 2025
    Systematic review386 participants8 studies pooledBone Health forMagnesium
  18. Vascularized bone grafting fixed by biodegradable magnesium screw for treating osteonecrosis of the femoral head.
    Zhao D; Huang S; Lu F; Wang B; Yang L; Qin L; Yang K; Li Y; Li W; Wang W; Tian S; Zhang X; Gao W; Wang Z; Zhang Y; Xie X; Wang J; Li J · Biomaterials · 2016
    Randomized trial48 participantsBone Health forMagnesium
  19. An update on magnesium and bone health.
    Rondanelli M; Faliva MA; Tartara A; Gasparri C; Perna S; Infantino V; Riva A; Petrangolini G; Peroni G · Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine · 2022
    Narrative reviewBone Health forMagnesium
  20. Sex-specific differences in the association of magnesium intake with femoral neck bone mineral density among older adults.
    Wang B; Tan X; Yao X; Zhu Z · Endocrine connections · 2025
    Cross-sectional study1,343 participantsBone Health forMagnesium